Inhibition of Notch1 signaling reduces abdominal aortic aneurysm in mice by attenuating macrophage-mediated inflammation

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 32, Issue 12, 2012, Pages 3012-3023

  Hans, Chetan P ^a,b   Koenig, Sara N ^a   Huang, Nianyuan ^a   Cheng, Jeeyun ^a   Beceiro, Susana ^a   Guggilam, Anuradha ^a,b   Kuivaniemi, Helena ^c   Partida Sánchez, Santiago ^a,b   Garg, Vidu ^a,b  

^a NATIONWIDE CHILDREN S HOSPITAL   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c WEIS CENTER FOR RESEARCH   (United States)

Author keywords

aneurysm; inflammation; macrophages; Notch1 signaling

Indexed keywords

ANGIOTENSIN II; APOLIPOPROTEIN E; NOTCH1 RECEPTOR;

ABDOMINAL AORTA ANEURYSM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CELL ISOLATION; CELL PROLIFERATION; CONTROLLED STUDY; FLOW CYTOMETRY; HAPLOINSUFFICIENCY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MACROPHAGE MIGRATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ANGIOTENSIN II; ANIMALS; AORTIC ANEURYSM, ABDOMINAL; APOLIPOPROTEINS E; ARTERITIS; DIPEPTIDES; DISEASE MODELS, ANIMAL; HAPLOINSUFFICIENCY; HUMANS; MACROPHAGES; MALE; MICE; MICE, KNOCKOUT; RECEPTOR, NOTCH1; SIGNAL TRANSDUCTION;

EID: 84870063353     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.112.254219     Document Type: Article

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