Epidermal growth factor (EGF) regulates α5β1 integrin activation state in human cancer cell lines through the p90RSK-dependent phosphorylation of filamin A

Journal of Biological Chemistry

Volumn 287, Issue 48, 2012, Pages 40371-40380

  Vial, Daniel ^a   McKeown Longo, Paula J ^a  

^a ALBANY MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION STATE; ACTIVE STATE; CELL LINES; CELL SURFACES; COLON CANCER CELLS; CYTOPLASMIC PROTEINS; EPIDERMAL GROWTH FACTORS; EXTRACELLULAR MATRICES; FUNCTIONAL ACTIVITIES; HUMAN CANCER CELLS; INHIBITORY EFFECT; INTEGRIN ACTIVATION; INTEGRIN RECEPTORS; INTEGRINS; INTRACELLULAR DOMAIN; LIGAND BINDING; SIGNALING PATHWAYS; SQUAMOUS CARCINOMA; TRANS-MEMBRANE PROTEINS; WILD TYPES;

CELL ADHESION; CELL CULTURE; CELL MEMBRANES; CLONE CELLS; ENZYMES; GLYCOPROTEINS; LIGANDS; PROTEINS;

PHOSPHORYLATION;

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; FIBRONECTIN; FILAMIN A; MITOGEN ACTIVATED PROTEIN KINASE; P90 RIBOSOMAL S6 KINASE; RHO FACTOR; RHO KINASE; S6 KINASE; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 5;

ARTICLE; CANCER CELL; CELL ADHESION; CELL SURFACE; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

AMINO ACID MOTIFS; CELL LINE, TUMOR; CONTRACTILE PROTEINS; EPIDERMAL GROWTH FACTOR; HUMANS; INTEGRIN ALPHA5BETA1; MICROFILAMENT PROTEINS; PHOSPHORYLATION; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA;

EID: 84870037413     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.389577     Document Type: Article

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