Pathogenetic and therapeutic perspectives on neurocognitive models in psychiatry: A synthesis of behavioral, brain imaging, and biological studies

Indian Journal of Psychiatry

Volumn 54, Issue 3, 2012, Pages 217-222

  Rao, Naren P ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES   (India)

Author keywords

Bipolar disorder; cognition; neuropsychology; obsessive compulsive disorder; schizophrenia

Indexed keywords

ATOMOXETINE; DONEPEZIL;

ALZHEIMER DISEASE; ARTICLE; ATTENTION; BASAL GANGLION; BEHAVIOR; BIPOLAR DISORDER; BRAIN DYSFUNCTION; BRAIN SIZE; COGNITION; CORPUS CALLOSUM; CORRELATION ANALYSIS; DECISION MAKING; DERMATOGLYPHICS; DISEASE SEVERITY; ELECTROCONVULSIVE THERAPY; ENDOPHENOTYPE; EPISODIC MEMORY; FLUENCY DISORDER; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GRAY MATTER; HIPPOCAMPUS; HUMAN; INTELLIGENCE; LEARNING; MENTAL PATIENT; META ANALYSIS (TOPIC); METHODOLOGY; NEUROIMAGING; OBSESSIVE COMPULSIVE DISORDER; ORBITAL CORTEX; PATHOGENESIS; PERCEPTION; PREFRONTAL CORTEX; PSYCHIATRY; PSYCHOLOGICAL MODEL; SCHIZOPHRENIA; SUPERIOR TEMPORAL GYRUS; VERBAL MEMORY; VOLUMETRY; VOXEL BASED MORPHOMETRY; WORKING MEMORY;

EID: 84870037406     PISSN: 00195545     EISSN: 19983794     Source Type: Journal    
DOI: 10.4103/0019-5545.102410     Document Type: Article

References (65)

1. Keefe RS. The contribution of neuropsychology to psychiatry. Am J Psychiatry 1995;152:6-15.
2. Kuelz AK, Hohagen F, Voderholzer U. Neuropsychological performance in obsessive-compulsive disorder: A critical review. BiolPsychol 2004;65:185-236.
3. Savage CR, Baer L, Keuthen NJ, Brown HD, Rauch SL, Jenike MA. Organizational strategies mediate nonverbal memory impairment in obsessive-compulsive disorder. Biol Psychiatry 1999;45:905-16.
4. MacDonald PA, Antony MM, Macleod CM, Richter MA. Memory and confidence in memory judgements among individuals with obsessive compulsive disorder and non-clinical controls. Behav Res Ther 1997;35:497-505.
5. Muller J, Roberts JE. Memory and attention in Obsessive-Compulsive Disorder: A review. J Anxiety Disord 2005;19:1-28.
6. Rao NP, Arasappa R, Reddy NN, Venkatasubramanian G, Reddy YC. Emotional interference in obsessive-compulsive disorder: A neuropsychological study using optimized emotional Stroop test. Psychiatry Res 2010;180:99-104.
7. Bannon S, Gonsalvez CJ, Croft RJ, Boyce PM. Executive functions in obsessive-compulsive disorder: state or trait deficits? Aust N Z J Psychiatry 2006;40:1031-8.
8. Rao NP, Reddy YC, Kumar KJ, Kandavel T, Chandrashekar CR. Are neuropsychological deficits trait markers in OCD? Prog Neuropsychopharmacol Biol Psychiatry 2008;32:1574-9.
9. Chamberlain SR, Menzies L, Hampshire A, Suckling J, Fineberg NA, del Campo N, et al. Orbitofrontal dysfunction in patients with obsessive-compulsive disorder and their unaffected relatives. Science 2008;321:421-2.
10. Chamberlain SR, Blackwell AD, Fineberg NA, Robbins TW, Sahakian BJ. The neuropsychology of obsessive compulsive disorder: The importance of failures in cognitive and behavioural inhibition as candidate endophenotypic markers. NeurosciBiobehav Rev 2005;29:399-419.
11. Dickinson D, Gold JM. Less unique variance than meets the eye: Overlap among traditional neuropsychological dimensions in schizophrenia. Schizophr Bull 2008;34:423-34.
12. Palmer BW, Dawes SE, Heaton RK. What do we know about neuropsychological aspects of schizophrenia? Neuropsychol Rev 2009;19:365-84.
13. Barnett KJ. Schizophrenia and rightward bias in line bisection. Laterality 2006;11:36-42.
14. Zivotofsky AZ, Edelman S, Green T, Fostick L, Strous RD. Hemisphere asymmetry in schizophrenia as revealed through line bisection, line trisection, and letter cancellation. Brain Res 2007;1142:70-9.
15. Jones P, Rodgers B, Murray R, Marmot M. Child development risk factors for adult schizophrenia in the British 1946 birth cohort. Lancet 1994;344:1398-402.
16. Rund BR. A review of longitudinal studies of cognitive functions in schizophrenia patients. Schizophr Bull 1998;24:425-35.
17. Egan MF, Goldberg TE, Gscheidle T, Weirich M, Rawlings R, Hyde TM, et al. Relative risk for cognitive impairments in siblings of patients with schizophrenia. Biol Psychiatry 2001;50:98-107.
18. Kurtz MM, Gerraty RT. A meta-analytic investigation of neurocognitive deficits in bipolar illness: Profile and effects of clinical state. Neuropsychology 2009;23:551-62.
19. Joseph MF, Frazier TW, Youngstrom EA, Soares JC. A quantitative and qualitative review of neurocognitive performance in pediatric bipolar disorder. J Child AdolescPsychopharmacol 2008;18:595-605.
20. Bora E, Yucel M, Pantelis C, Berk M. Meta-analytic review of neurocognition in bipolar II disorder. ActaPsychiatr Scand. 2011;123:165-74.
21. Besnier N, Kaladjian A, Mazzola-Pomietto P, Adida M, Fakra E, Jeanningros R, et al. Differential responses to emotional interference in paranoid schizophrenia and bipolar mania. Psychopathology 2011;44:1-11.
22. Williams JM, Mathews A, MacLeod C. The emotional stroop task and psychopathology. Psychol Bull 1996;120:3-24.
23. Besnier N, Richard F, Zendjidjian X, Kaladjian A, Mazzola-Pomietto P, Adida M, et al. Stroop and emotional Stroop interference in unaffected relatives of patients with schizophrenic and bipolar disorders: Distinct markers of vulnerability? World J Biol Psychiatry 2009;10:809-18.
24. Jabben N, Arts B, van Os J, Krabbendam L. Neurocognitive functioning as intermediary phenotype and predictor of psychosocial functioning across the psychosis continuum: Studies in schizophrenia and bipolar disorder. J Clin Psychiatry 2010;71:764-74.
25. Rao NP, Arasappa R, Reddy NN, Venkatasubramanian G, Gangadhar BN. Antithetical asymmetry in schizophrenia and bipolar affective disorder: A line bisection study. Bipolar Disord 2010;12:221-9.
26. Jenike MA, Rauch SL, Cummings JL, Savage CR, Goodman WK. Recent developments in neurobiology of obsessive-compulsive disorder. J Clin Psychiatry 1996;57:492-503.
27. Calabrese G, Colombo C, Bonfanti A, Scotti G, Scarone S. Caudate nucleus abnormalities in obsessive-compulsive disorder: Measurements of MRI signal intensity. Psychiatry Res 1993;50:89-92.
28. Baxter LR, Jr. Neuroimaging studies of obsessive compulsive disorder. PsychiatrClin North Am. 1992;15:871-84.
29. Saxena S, Brody AL, Maidment KM, Dunkin JJ, Colgan M, Alborzian S, et al. Localized orbitofrontal and subcortical metabolic changes and predictors of response to paroxetine treatment in obsessive-compulsive disorder. Neuropsychopharmacology 1999;21:683-93.
30. Swedo SE, Pietrini P, Leonard HL, Schapiro MB, Rettew DC, Goldberger EL, et al. Cerebral glucose metabolism in childhood-onset obsessive-compulsive disorder. Revisualization during pharmacotherapy. Arch Gen Psychiatry. 1992;49:690-4.
31. McCarley RW, Wible CG, Frumin M, Hirayasu Y, Levitt JJ, Fischer IA, et al. MRI anatomy of schizophrenia. Biol Psychiatry. 1999;45:1099-119.
32. Buchanan RW, Francis A, Arango C, Miller K, Lefkowitz DM, McMahon RP, et al. Morphometric assessment of the heteromodal association cortex in schizophrenia. Am J Psychiatry 2004;161:322-31.
33. Woodruff PW, McManus IC, David AS. Meta-analysis of corpus callosum size in schizophrenia. J NeurolNeurosurg Psychiatry 1995;58:457-61.
34. Arasappa R, Rao NP, Venkatasubramanian G, Jayakumar P, Gangadhar BN. Structural cerebellar abnormalities in antipsychotic naïve schizophrenia: Evidence for cognitive dysmetria. Ind J Psychol Med 2008:83-9.
35. Rao NP, Venkatasubramanian G, Arasappa R, Gangadhar BN. Relationship between corpus callosum abnormalities and schneiderian first-rank symptoms in antipsychotic-naive schizophrenia patients. J Neuropsychiatry ClinNeurosci 2011;23:155-62.
36. Rao NP, Kalmady S, Arasappa R, Venkatasubramanian G. Clinical correlates of thalamus volume deficits in anti-psychotic-naive schizophrenia patients: A 3-Tesla MRI study. Indian J Psychiatry 2010;52:229-35.
37. Weinberger DR, Berman KF. Prefrontal function in schizophrenia: Confounds and controversies. Philos Trans R SocLond B Biol Sci. 1996;351:1495-503.
38. Weinberger DR, Mattay V, Callicott J, Kotrla K, Santha A, van Gelderen P, et al. FMRI applications in schizophrenia research. Neuroimage. 1996;4(3 Pt 3):S118-26.
39. Ganesan V, Hunter MD, Spence SA. Schneiderian first-rank symptoms and right parietal hyperactivation: A replication using FMRI. Am J Psychiatry 2005;162:1545.
40. Hunter MD, Ganesan V, Wilkinson ID, Spence SA. Impact of modafinil on prefrontal executive function in schizophrenia. Am J Psychiatry 2006;163:2184-6.
41. Danivas V, Kalmady S, Arasappa R, Behere RV, Rao NP, Venkatasubramanian G, et al. Inferior parietal lobule volume and schneiderian first-rank symptoms in antipsychotic-naive schizophrenia: A 3-tesla MRI study. Indian J Psychol Med 2009;31:82-7.
42. Drevets WC, Price JL, Simpson JR, Jr, Todd RD, Reich T, Vannier M, et al. Subgenual prefrontal cortex abnormalities in mood disorders. Nature 1997;386:824-7.
43. Doris A, Belton E, Ebmeier KP, Glabus MF, Marshall I. Reduction of cingulate gray matter density in poor outcome bipolar illness. Psychiatry Res 2004;130:153-9.
44. Blumberg HP, Krystal JH, Bansal R, Martin A, Dziura J, Durkin K, et al. Age, rapid-cycling, and pharmacotherapy effects on ventral prefrontal cortex in bipolar disorder: A cross-sectional study. Biol Psychiatry 2006;59:611-8.
45. Womer FY, Kalmar JH, Wang F, Blumberg HP. A ventral Prefrontal-amygdala neural system in bipolar disorder: A view from neuroimaging research. ActaNeuropsychiatr 2009;21:228-38.
46. Dickstein DP, Milham MP, Nugent AC, Drevets WC, Charney DS, Pine DS, et al. Frontotemporal alterations in pediatric bipolar disorder: Results of a voxel-based morphometry study. Arch Gen Psychiatry 2005;62:734-41.
47. Chepenik LG, Fredericks C, Papademetris X, Spencer L, Lacadie C, Wang F, et al. Effects of the brain-derived neurotrophic growth factor val66met variation on hippocampus morphology in bipolar disorder. Neuropsychopharmacology. 2009;34:944-51.
48. Del Bello MP, Strakowski SM, Zimmerman ME, Hawkins JM, Sax KW. MRI analysis of the cerebellum in bipolar disorder: A pilot study. Neuropsychopharmacology. 1999;21:63-8.
49. Hwang J, Lyoo IK, Dager SR, Friedman SD, Oh JS, Lee JY, et al. Basal ganglia shape alterations in bipolar disorder. Am J Psychiatry. 2006;163:276-85.
50. Lawrence NS, Williams AM, Surguladze S, Giampietro V, Brammer MJ, Andrew C, et al. Subcortical and ventral prefrontal cortical neural responses to facial expressions distinguish patients with bipolar disorder and major depression. Biol Psychiatry. 2004;55:578-87.
51. Blumberg HP, Martin A, Kaufman J, Leung HC, Skudlarski P, Lacadie C, et al. Frontostriatal abnormalities in adolescents with bipolar disorder: Preliminary observations from functional MRI. Am J Psychiatry 2003;160:1345-7.
52. Ketter TA, Kimbrell TA, George MS, Dunn RT, Speer AM, Benson BE, et al. Effects of mood and subtype on cerebral glucose metabolism in treatment-resistant bipolar disorder. Biol Psychiatry 2001;49:97-109.
53. Venkatasubramanian G, Arasappa R, Rao NP, Gangadhar BN. Digit ratio (2D:4D) asymmetry and schneiderian first rank symptoms: Implications for cerebral lateralisation theories of schizophrenia. Laterality 2010;16:499-512.
54. Rao NP, Venkatasubramanian G, Kalmady SV, Behere RV, Arasappa R, Gangadhar BN. Neuroanatomical correlates of dermatoglyphic complexity index in antipsychotic-naïve schizophrenia. Schizophr Res 2010;117:435-6.
55. Freedman M. Object alternation and orbitofrontal system dysfunction in Alzheimer's and Parkinson's disease. Brain Cogn 1990;14:134-43.
56. Zald DH, Curtis C, Folley BS, Pardo JV. Prefrontal contributions to delayed spatial and object alternation: A positron emission tomography study. Neuropsychology 2002;16:182-9.
57. van den Heuvel OA, Veltman DJ, Groenewegen HJ, Witter MP, Merkelbach J, Cath DC, et al. Disorder-specific neuroanatomical correlates of attentional bias in obsessive-compulsive disorder, panic disorder, and hypochondriasis. Arch GenPsychiatry 2005;62:922-33.
58. Reddy YC, Rao NP, Khanna S. An overview of Indian research in obsessive compulsive disorder. Indian J Psychiatry 2010;52:S200-9.
59. Cohen Y, Lachenmeyer JR, Springer C. Anxiety and selective attention in obsessive-compulsive disorder. Behav Res Ther 2003;41:1311-23.
60. Beck AT, Clark DA. An information processing model of anxiety: Automatic and strategic processes. Behav Res Ther 1997;35:49-58.
61. Salkovskis PM. Understanding and treating obsessive-compulsive disorder. Behav Res Ther 1999;37(Suppl 1):S29-52.
62. Frith CD, Blakemore S, Wolpert DM. Explaining the symptoms of schizophrenia: Abnormalities in the awareness of action. Brain Res Brain Res Rev 2000;31:357-63.
63. Rolls ET. The functions of the orbitofrontal cortex. Brain Cogn 2004;55:11-29.
64. Rao NP, Venkatasubramanian G, Gangadhar BN. Treatment of cognitive deficits in schizophrenia with atomoxetine: A case report. J Clin Psychiatry. 2007;68:1988-9.
65. Rao NP, Palaniyappan P, Chandur J, Venkatasubramanian G, Gangadhar BN. Successful use of donepezil in treatment of cognitive impairment caused by maintenance electroconvulsive therapy: A case report. J ECT 2009;25:216-8.