Digit ratio (2D:4D) asymmetry and schneiderian first rank symptoms: Implications for cerebral lateralisation theories of schizophrenia

Laterality

Volumn 16, Issue 4, 2011, Pages 499-512

  Venkatasubramanian, Ganesan ^a   Arasappa, Rashmi ^a   Rao, Naren P ^a   Gangadhar, Bangalore N ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES   (India)

Author keywords

Cerebral lateralisation; Digit ratio; Schizophrenia; Schneiderian first rank symptoms

Indexed keywords

ADULT; ARTICLE; FEMALE; FINGER; GROWTH, DEVELOPMENT AND AGING; HEMISPHERIC DOMINANCE; HUMAN; MALE; MORPHOGENESIS; PATHOPHYSIOLOGY; PHYSIOLOGY; PRENATAL DEVELOPMENT; SCHIZOPHRENIA;

ADULT; BODY PATTERNING; DOMINANCE, CEREBRAL; FEMALE; FINGERS; FUNCTIONAL LATERALITY; HUMANS; MALE; SCHIZOPHRENIA; YOUNG ADULT;

EID: 79960477765     PISSN: 1357650X     EISSN: 14640678     Source Type: Journal    
DOI: 10.1080/1357650X.2010.499910     Document Type: Article

References (49)

1. Annett, M. (1967). The binomial distribution of right, mixed and left handedness. The Quarterly Journal of Experimental Psychology, 19, 327-333.
2. Arato, M., Frecska, E., Beck, C, An, M., & Kiss, H. (2004). Digit length pattern in schizophrenia suggests disturbed prenatal hemispheric lateralisation. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 28, 191-194.
3. Blanco, P., Sargent, C. A., Boucher, C. A., Mitchell, M., & Affara, N. A. (2000). Conservation of PCDHX in mammals; expression of human X/Y genes predominantly in brain. Mammalian Genome, 11, 906-914.
4. Bleich-Cohen, M., Hendler, T., Kotler, M., & Strous, R. D. (2009). Reduced language lateralization in first-episode schizophrenia: An fMRI index of functional asymmetry. Psychiatry Research, 171, 82-93.
5. Bourne, V. J., & Gray, D. L. (2009). Hormone exposure and functional lateralisation: examining the contributions of prenatal and later life hormonal exposure. Psychoneuroendocrinology, 34, 1214-1221.
6. Broca, P. (1877). Rapport sur un memoire de M. Armand de Fleury intitule: de l'inegalite dynamique des deux hemispheres cerebraux. Bulletin de l'Academie de Medicine, 6, 508-539.
7. Buchanan, R. W., Francis, A., Arango, C, Miller, K., Lefkowitz, D. M., Mcmahon, R. P., et al. (2004). Morphometric assessment of the heteromodal association cortex in schizophrenia. The American Journal of Psychiatry, 161, 322-331.
8. Chura, L. R., Lombardo, M. V, Ashwin, E., Auyeung, B., Chakrabarti, B., Bullmore, E. T., et al. (2010). Organizational effects of fetal testosterone on human corpus callosum size and asymmetry. Psychoneuroendocrinology, 35, 122-132.
9. Crow, T. J. (2000). Schizophrenia as the price that Homo sapiens pays for language: A resolution of the central paradox in the origin of the species. Brain Research. Brain Research Reviews, 31, 118-129.
10. Crow, T. J. (2002). Handedness, language lateralisation and anatomical asymmetry: Relevance of protocadherin XY to hominid speciation and the aetiology of psychosis. Point of view. The British Journal of Psychiatry, 181, 295-297.
11. Crow, T. J. (2004). Cerebral asymmetry and the lateralisation of language: Core deficits in schizophrenia as pointers to the gene. Current Opinion in Psychiatry, 17, 97-106.
12. Crow, T. J. (2008). The 'big bang' theory of the origin of psychosis and the faculty of language. Schizophrenia Research, 102, 31-52.
13. Flor-Henry, P. (1983). Determinants of psychosis in epilepsy: Laterality and forced normalization. Biological Psychiatry, 18, 1045-1057.
14. Foundas, A. L., Leonard, C. M., & Heilman, K. M. (1995). Morphologic cerebral asymmetries and handedness. The pars triangularis and planum temporale. Archives of Neurology, 52, 501-508.
15. Geerts, M., Steyaert, J., & Fryns, J. P. (2003). The XYY syndrome: A follow-up study on 38 boys. Genetic Counseling, 14, 267-279.
16. Geschwind, N., & Galaburda, A. M. (1985a). Cerebral lateralisation. Biological mechanisms, associations, and pathology: I. A hypothesis and a program for research. Archives of Neurology, 42, 428-59.
17. Geschwind, N., & Galaburda, A. M. (1985b). Cerebral lateralisation. Biological mechanisms, associations, and pathology: II. A hypothesis and a program for research. Archives of Neurology, 42, 521-552.
18. Geschwind, N., & Galaburda, A. M. (1985c). Cerebral lateralisation. Biological mechanisms, associations, and pathology: III. A hypothesis and a program for research. Archives of Neurology, 42, 634-654.
19. Gobrogge, K. L., Breedlove, S. M., & Klump, K. L. (2008). Genetic and environmental influences on 2D:4D finger length ratios: A study of monozygotic and dizygotic male and female twins. Archives of Sexual Behavior, 37, 112-118.
20. Goldberg, D. P., Gater, R., Sartorius, N., Ustun, T. B., Piccinelli, M., Gureje, O., et al. (1997). The validity of two versions of the GHQ in the WHO study of mental illness in general health care. Psychological Medicine, 27, 191-197.
21. Highley, J. R., Walker, M. A., McDonald, B., Crow, T. J., & Esiri, M. M. (2003). Size of hippocampal pyramidal neurons in schizophrenia. The British Journal of Psychiatry, 183, 414-417.
22. Kallai, J., Csatho, A., Kover, F., Makany, T, Nemes, J., Horvath, K., et al. (2005). MRI-assessed volume of left and right hippocampi in females correlates with the relative length of the second and fourth fingers (the 2D:4D ratio). Psychiatry Research, 140, 199-210.
23. Kalmady, S. V., & Venkatasubramanian, G (2009). Evidence for positive selection on Protocadherin Y gene in Homo sapiens: Implications for schizophrenia. Schizophrenia Research, 108, 299-300.
24. Loberg, E. M., Jorgensen, H. A., Green, M. F., Rund, B. R., Lund, A., Diseth, A., et al. (2006). Positive symptoms and duration of illness predict functional laterality and attention modulation in schizophrenia. Acta Psychiatrica Scandinavica, 113, 322-331.
25. th digit ratios, fetal testosterone and estradiol. Early Human Development, 77, 23-28.
26. Manning, J. T, Barley, L., Walton, J., Lewis-Jones, D. I., Trivers, R. L., Singh, D., et al. (2000). The 2nd:4th digit ratio, sexual dimorphism, population differences, and reproductive success. evidence for sexually antagonistic genes? Evolution and Human Behavior, 21, 163-183.
27. Manning, J. T., & Bundred, P. E. (2000). The ratio of 2nd to 4th digit length: A new predictor of disease predisposition? Medical Hypotheses, 54, 855-857.
28. Manning, J. T., & Peters, M. (2009). Digit ratio (2D:4D) and hand preference for writing in the BBC Internet Study. Laterality, 14, 528-540.
29. Manning, J. T., Scutt, D., Wilson, J., & Lewis-Jones, D. I. (1998). The ratio of 2nd to 4th digit length: A predictor of sperm numbers and concentrations of testosterone, luteinizing hormone and oestrogen. Human Reproduction, 13, 3000-3004.
30. McIntyre, M. H. (2006). The use of digit ratios as markers for perinatal androgen action. Reproductive Biology and Endocrinology, 4, 10.
31. Mellor, C. S. (1970). First rank symptoms of schizophrenia. I. The frequnncy in schizophrenics on admission to hospital. II. Differences between individual first rank symptoms. The British Journal of Psychiatry, 117, 15-23.
32. Oertel, V, Knochel, C, Rotarska-Jagiela, A., Schonmeyer, R., Lindner, M., Van De Ven, V, et al. (2010). Reduced laterality as a trait marker of schizophrenia - evidence from structural and functional neuroimaging. The Journal of Neuroscience, 30, 2289-2299.
33. Priddle, T. H., & Crow, T. J. (2009). The protocadherin 11X/Y gene pair as a putative determinant of cerebral dominance in Homo sapiens. Future Neurology, 4, 509-518.
34. Procopio, M., Davies, R. J., & Marriott, P. (2006). The hormonal environment in utero as a potential aetiological agent for schizophrenia. European Archives of Psychiatry and Clinical Neuroscience, 256, 77-81.
35. Qiu, A., Wang, L., Younes, L., Harms, M. P., Ratnanather, J. T, Miller, M. I., et al. (2009). Neuroanatomical asymmetry patterns in individuals with schizophrenia and their non-psychotic siblings. Neuroimage, 47, 1221-1229.
36. Razafimandimby, A., Maiza, O., Herve, P. Y, Lecardeur, L., Delamillieure, P., Brazo, P., et al. (2007). Stability of functional language lateralisation over time in schizophrenia patients. Schizophrenia Research, 94, 197-206.
37. Sallet, P. C, Elkis, H., Alves, T. M., Oliveira, J. R., Sassi, E., De Castro, C. C, et al. (2003). Rightward cerebral asymmetry in subtypes of schizophrenia according to Leonhard's classification and to DSM-IV: A structural MRI study. Psychiatry Research, 123, 65-79.
38. Sheehan, D. V., Lecrubier, Y, Sheehan, K. H., Amorim, P., Janavs, J., Weiller, E., et al. (1998). The Mini-International Neuropsychiatric Interview (M.I.N.I.): The development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. The Journal of Clinical Psychiatry, 59(Suppl 20), 22-33; quiz 34-57.
39. Sims, A. (1991). An overview of the psychopathology of perception: First rank symptoms as a localizing sign in schizophrenia. Psychopathology, 24, 369-374.
40. Sommer, I., Ramsey, N., Kahn, R., Aleman, A., & Bouma, A. (2001). Handedness, language lateralisation and anatomical asymmetry in schizophrenia: Meta-analysis. The British Journal of Psychiatry, 178, 344-351.
41. Stoyanov, Z., Marinov, M., & Pashalieva, I. (2009). Finger length ratio (2D:4D) in left-and right-handed males. The International Journal of Neuroscience, 119, 1006-1013.
42. Suzuki, M., Zhou, S. Y, Hagino, H., Niu, L., Takahashi, T, Kawasaki, Y, et al. (2005). Morphological brain changes associated with Schneider's first-rank symptoms in schizophrenia: A MRI study. Psychological Medicine, 35, 549-560.
43. Verdoux, H., Liraud, F, Droulout, T, Theillay, G., Parrot, M., & Franck, N. (2004). Is the intensity of Schneiderian symptoms related to handedness and speech disorder in subjects with psychosis? Schizophrenia Research, 67, 167-173.
44. Voracek, M., & Dressler, S. G. (2009). Brief communication: Familial resemblance in digit ratio (2D:4D). American Journal of Physical Anthropology, 140, 376-380.
45. Walker, M. A., Highley, J. R., Esiri, M. M., McDonald, B., Roberts, H. C, Evans, S. P., et al. (2002). Estimated neuronal populations and volumes of the hippocampus and its subfields in schizophrenia. The American Journal of Psychiatry, 159, 821-828.
46. Weiss, E. M., Hofer, A., Golaszewski, S., Siedentopf, C, Felber, S., & Fleischhacker, W. W. (2006). Language lateralisation in unmedicated patients during an acute episode of schizophrenia: A functional MRI study. Psychiatry Research, 146, 185-190.
47. Williams, N. A., Close, J. P., Giouzeli, M., & Crow, T. J. (2006). Accelerated evolution of Protocadherin11X/Y: A candidate gene-pair for cerebral asymmetry and language. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics, 141B, 623-633.
48. Yoshida, K., & Sugano, S. (1999). Identification of a novel protocadherin gene (PCDH11) on the human XY homology region in Xq21.3. Genomics, 62, 540-543.
49. Ypsilanti, A., Ganou, M., Koidou, I., & Grouios, G (2008). Digit ratio (2D:4D) in individuals with intellectual disability: Investigating the role of testosterone in the establishment of cerebral lateralisation. Laterality, 13, 527-544.