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Volumn 35, Issue 4, 2012, Pages 243-257

Discovery of TP53 splice variants in two novel papillary urothelial cancer cell lines

Author keywords

133 isoform; Bladder cancer; FGFR3; P53 alternative promoter; Papillary urothelial carcinoma; Rs17878362 intronic polymorphism

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; DNA POLYMERASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE CA; PROTEIN P53; UNCLASSIFIED DRUG;

EID: 84870027169     PISSN: 22113428     EISSN: 22113436     Source Type: Journal    
DOI: 10.1007/s13402-012-0082-8     Document Type: Review
Times cited : (13)

References (37)
  • 1
    • 77955864162 scopus 로고    scopus 로고
    • Diagnosis and classification of flat, papillary, and invasive urothelial carcinoma: The who/isup consensus
    • J.I. Epstein, Diagnosis and classification of flat, papillary, and invasive urothelial carcinoma: the WHO/ISUP consensus. Int. J. Surg. Pathol. 18, 106S-111S (2010)
    • (2010) Int. J. Surg. Pathol , vol.18
    • Epstein, J.I.1
  • 2
    • 33747506490 scopus 로고    scopus 로고
    • Understanding urothelial carcinoma through cancer pathways
    • DOI 10.1002/ijc.21852
    • W.A. Schulz, Understanding urothelial carcinoma through cancer pathways. Int. J. Cancer 119, 1513-1518 (2006) (Pubitemid 44258755)
    • (2006) International Journal of Cancer , vol.119 , Issue.7 , pp. 1513-1518
    • Schulz, W.A.1
  • 3
    • 78650191856 scopus 로고    scopus 로고
    • Signal transduction in urothelial cancer : How exactly do we know the targets for targeted therapy?
    • G. Niegisch, A. Koch, J. Knievel, W.A. Schulz, P. Albers, Signal transduction in urothelial cancer : How exactly do we know the targets for targeted therapy?. Urologe A (2010)
    • (2010) Urologe A
    • Niegisch, G.1    Koch, A.2    Knievel, J.3    Schulz, W.A.4    Albers, P.5
  • 4
    • 77953819013 scopus 로고    scopus 로고
    • Bladder cancer or bladder cancers? Genetically distinct malignant conditions of the urothelium
    • P.J. Goebell, M.A. Knowles, Bladder cancer or bladder cancers? Genetically distinct malignant conditions of the urothelium. Urol. Oncol. 28, 409-428 (2010)
    • (2010) Urol. Oncol , vol.28 , pp. 409-428
    • Goebell, P.J.1    Knowles, M.A.2
  • 7
    • 73949117703 scopus 로고    scopus 로고
    • Massively regulated genes: The example of tp53
    • M. Hollstein, P. Hainaut, Massively regulated genes: the example of TP53. J. Pathol. 220, 164-173 (2010)
    • (2010) J. Pathol , vol.220 , pp. 164-173
    • Hollstein, M.1    Hainaut, P.2
  • 9
    • 77956935083 scopus 로고    scopus 로고
    • P53 isoforms gain functions
    • V. Olivares-Illana, R. Fahraeus, p53 isoforms gain functions. Oncogene 29, 5113-5119 (2010)
    • (2010) Oncogene , vol.29 , pp. 5113-5119
    • Olivares-Illana, V.1    Fahraeus, R.2
  • 10
    • 80052604378 scopus 로고    scopus 로고
    • Transcriptional and epigenetic regulation of the p53 tumor suppressor gene
    • R. Saldana-Meyer, F. Recillas-Targa, Transcriptional and epigenetic regulation of the p53 tumor suppressor gene. Epigenetics 6 (2011)
    • (2011) Epigenetics , vol.6
    • Saldana-Meyer, R.1    Recillas-Targa, F.2
  • 11
    • 80053015725 scopus 로고    scopus 로고
    • P53 isoforms: An intracellular microprocessor?
    • M.P. Khoury, J.C. Bourdon, p53 isoforms: an intracellular microprocessor? Genes Cancer. 2, 453-465 (2011)
    • (2011) Genes Cancer , vol.2 , pp. 453-465
    • Khoury, M.P.1    Bourdon, J.C.2
  • 12
    • 0037209115 scopus 로고    scopus 로고
    • Splice mutations in the p53 gene: Case report and review of the literature
    • R. Holmila, C. Fouquet, J. Cadranel, G. Zalcman, T. Soussi, Splice mutations in the p53 gene: case report and review of the literature. Hum. Mutat. 21, 101-102 (2003)
    • (2003) Hum. Mutat , vol.21 , pp. 101-102
    • Holmila, R.1    Fouquet, C.2    Cadranel, J.3    Zalcman, G.4    Soussi, T.5
  • 14
    • 0034603728 scopus 로고    scopus 로고
    • P53 splice acceptor site mutation and increased HsRAD51 protein expression in Bloom's syndrome GM1492 fibroblasts
    • DOI 10.1016/S0378-1119(00)00068-8, PII S0378111900000688
    • K.P. Magnusson, M. Sandstrom, M. Stahlberg, M. Larsson, J. Flygare, D. Hellgren, K.G. Wiman, S. Ljungquist, p53 splice acceptor site mutation and increased HsRAD51 protein expression in Bloom's syndrome GM1492 fibroblasts. Gene 246, 247-254 (2000) (Pubitemid 30190178)
    • (2000) Gene , vol.246 , Issue.1-2 , pp. 247-254
    • Magnusson, K.P.1    Sandstrom, M.2    Stahlberg, M.3    Larsson, M.4    Flygare, J.5    Hellgren, D.6    Wiman, K.G.7    Ljungquist, S.8
  • 16
    • 0028152842 scopus 로고
    • Normal human urothelial cells in vitro: Proliferation and induction of stratification
    • J. Southgate, K.A. Hutton, D.F. Thomas, L.K. Trejdosiewicz, Normal human urothelial cells in vitro: proliferation and induction of stratification. Lab Invest. 71, 583-594 (1994) (Pubitemid 24338167)
    • (1994) Laboratory Investigation , vol.71 , Issue.4 , pp. 583-594
    • Southgate, J.1    Hutton, K.A.R.2    Thomas, D.F.M.3    Trejdosiewicz, L.K.4
  • 17
    • 24744471011 scopus 로고    scopus 로고
    • Causes and consequences of DNA hypomethylation in human cancer
    • DOI 10.1139/o05-036
    • M.J. Hoffmann, W.A. Schulz, Causes and consequences of DNA hypomethylation in human cancer. Biochem. Cell Biol. 83, 296-321 (2005) (Pubitemid 41297199)
    • (2005) Biochemistry and Cell Biology , vol.83 , Issue.3 , pp. 296-321
    • Hoffmann, M.J.1    Schulz, W.A.2
  • 18
    • 0033787302 scopus 로고    scopus 로고
    • Dna methylation and the mechanisms of cdkn2a inactivation in transitional cell carcinoma of the urinary bladder
    • A.R. Florl, K.H. Franke, D. Niederacher, C.D. Gerharz, H.H. Seifert, W.A. Schulz, DNA methylation and the mechanisms of CDKN2A inactivation in transitional cell carcinoma of the urinary bladder. Lab Invest. 80, 1513-1522 (2000)
    • (2000) Lab Invest , vol.80 , pp. 1513-1522
    • Florl, A.R.1    Franke, K.H.2    Niederacher, D.3    Gerharz, C.D.4    Seifert, H.H.5    Schulz, W.A.6
  • 19
    • 70249105783 scopus 로고    scopus 로고
    • No mutations of fgfr3 in normal urothelium in the vicinity of urothelial carcinoma of the bladder harbouring activating fgfr3 mutations in patients with bladder cancer
    • W. Otto, S. Denzinger, S. Bertz, A. Gaumann, P.J. Wild, A. Hartmann, R. Stoehr, No mutations of FGFR3 in normal urothelium in the vicinity of urothelial carcinoma of the bladder harbouring activating FGFR3 mutations in patients with bladder cancer. Int. J. Cancer 125, 2205-2208 (2009)
    • (2009) Int. J. Cancer , vol.125 , pp. 2205-2208
    • Otto, W.1    Denzinger, S.2    Bertz, S.3    Gaumann, A.4    Wild, P.J.5    Hartmann, A.6    Stoehr, R.7
  • 22
    • 77949542183 scopus 로고    scopus 로고
    • Nomenclature evolution: Changes in the iscn from the 2005 to the 2009 edition
    • A.R. Brothman, D.L. Persons, L.G. Shaffer, Nomenclature evolution: changes in the ISCN from the 2005 to the 2009 edition. Cytogenet Genome Res. 127, 1-4 (2009)
    • (2009) Cytogenet Genome Res , vol.127 , pp. 1-4
    • Brothman, A.R.1    Persons, D.L.2    Shaffer, L.G.3
  • 23
    • 16344395666 scopus 로고    scopus 로고
    • CyDAS: A cytogenetic data analysis system
    • DOI 10.1093/bioinformatics/bti146
    • B. Hiller, J. Bradtke, H. Balz, H. Rieder, CyDAS: a cytogenetic data analysis system. Bioinformatics 21, 1282-1283 (2005) (Pubitemid 40467962)
    • (2005) Bioinformatics , vol.21 , Issue.7 , pp. 1282-1283
    • Hiller, B.1    Bradtke, J.2    Balz, H.3    Rieder, H.4
  • 25
    • 33747358598 scopus 로고    scopus 로고
    • Expression of htert immortalises normal human urothelial cells without inactivation of the p16/rb pathway
    • E.J. Chapman, C.D. Hurst, E. Pitt, P. Chambers, J.S. Aveyard, M.A. Knowles, Expression of hTERT immortalises normal human urothelial cells without inactivation of the p16/Rb pathway. Oncogene 25, 5037-5045 (2006)
    • (2006) Oncogene , vol.25 , pp. 5037-5045
    • Chapman, E.J.1    Hurst, C.D.2    Pitt, E.3    Chambers, P.4    Aveyard, J.S.5    Knowles, M.A.6
  • 26
    • 51649112247 scopus 로고    scopus 로고
    • Genes involved in differentiation, stem cell renewal, and tumorigenesis are modulated in telomerase-immortalized human urothelial cells
    • E.J. Chapman, G. Kelly, M.A. Knowles, Genes involved in differentiation, stem cell renewal, and tumorigenesis are modulated in telomerase-immortalized human urothelial cells. Mol. Cancer Res. 6, 1154-1168 (2008)
    • (2008) Mol. Cancer Res , vol.6 , pp. 1154-1168
    • Chapman, E.J.1    Kelly, G.2    Knowles, M.A.3
  • 27
    • 40749102501 scopus 로고    scopus 로고
    • Sensitivity of normal, paramalignant, and malignant human urothelial cells to inhibitors of the epidermal growth factor receptor signaling pathway
    • DOI 10.1158/1541-7786.MCR-07-0134
    • N.J. MacLaine, M.D. Wood, J.C. Holder, R.W. Rees, J. Southgate, Sensitivity of normal, paramalignant, and malignant human urothelial cells to inhibitors of the epidermal growth factor receptor signaling pathway. Mol. Cancer Res. 6, 53-63 (2008) (Pubitemid 351378166)
    • (2008) Molecular Cancer Research , vol.6 , Issue.1 , pp. 53-63
    • MacLaine, N.J.1    Wood, M.D.2    Holder, J.C.3    Rees, R.W.4    Southgate, J.5
  • 29
    • 77953815362 scopus 로고    scopus 로고
    • P53 immunohistochemistry in bladder cancer-A new approach to an old question
    • P.J. Goebell, S.G. Groshen, B.J. Schmitz-Drager, p53 immunohistochemistry in bladder cancer -a new approach to an old question. Urol. Oncol. 28, 377-388 (2010)
    • (2010) Urol. Oncol , vol.28 , pp. 377-388
    • Goebell, P.J.1    Groshen, S.G.2    Schmitz-Drager, B.J.3
  • 31
    • 77952239067 scopus 로고    scopus 로고
    • P53 regulates the transcription of its delta133p53 isoform through specific response elements contained within the tp53 p2 internal promoter
    • V. Marcel, V. Vijayakumar, L. Fernandez-Cuesta, H. Hafsi, C. Sagne, A. Hautefeuille, M. Olivier, P. Hainaut, p53 regulates the transcription of its Delta133p53 isoform through specific response elements contained within the TP53 P2 internal promoter. Oncogene 29, 2691-2700 (2010)
    • (2010) Oncogene , vol.29 , pp. 2691-2700
    • Marcel, V.1    Vijayakumar, V.2    Fernandez-Cuesta, L.3    Hafsi, H.4    Sagne, C.5    Hautefeuille, A.6    Olivier, M.7    Hainaut, P.8
  • 33
    • 59949088362 scopus 로고    scopus 로고
    • P53 isoform delta113p53 is a p53 target gene that antagonizes p53 apoptotic activity via bclxl activation in zebrafish
    • J. Chen, S.M. Ng, C. Chang, Z. Zhang, J.C. Bourdon, D.P. Lane, J. Peng, p53 isoform delta113p53 is a p53 target gene that antagonizes p53 apoptotic activity via BclxL activation in zebrafish. Genes Dev. 23, 278-290 (2009)
    • (2009) Genes Dev , vol.23 , pp. 278-290
    • Chen, J.1    Ng, S.M.2    Chang, C.3    Zhang, Z.4    Bourdon, J.C.5    Lane, D.P.6    Peng, J.7
  • 34
    • 52049108964 scopus 로고    scopus 로고
    • Genetic variants in cell cycle control pathway confer susceptibility to bladder cancer
    • Y. Ye, H. Yang, H.B. Grossman, C. Dinney, X. Wu, J. Gu, Genetic variants in cell cycle control pathway confer susceptibility to bladder cancer. Cancer 112, 2467-2474 (2008)
    • (2008) Cancer , vol.112 , pp. 2467-2474
    • Ye, Y.1    Yang, H.2    Grossman, H.B.3    Dinney, C.4    Wu, X.5    Gu, J.6
  • 36
    • 77950863858 scopus 로고    scopus 로고
    • Three common tp53 polymorphisms in susceptibility to breast cancer, evidence from meta-analysis
    • Z. Hu, X. Li, R. Yuan, B.Z. Ring, L. Su, Three common TP53 polymorphisms in susceptibility to breast cancer, evidence from meta-analysis. Breast Cancer Res. Treat. 120, 705-714 (2010)
    • (2010) Breast Cancer Res. Treat , vol.120 , pp. 705-714
    • Hu, Z.1    Li, X.2    Yuan, R.3    Ring, B.Z.4    Su, L.5
  • 37
    • 18844448732 scopus 로고    scopus 로고
    • Autocrine regulation of human urothelial cell proliferation and migration during regenerative responses in vitro
    • DOI 10.1016/j.yexcr.2005.02.004, PII S0014482705000558
    • C. Varley, G. Hill, S. Pellegrin, N.J. Shaw, P.J. Selby, L.K. Trejdosiewicz, J. Southgate, Autocrine regulation of human urothelial cell proliferation and migration during regenerative responses in vitro. Exp. Cell Res. 306, 216-229 (2005) (Pubitemid 40692785)
    • (2005) Experimental Cell Research , vol.306 , Issue.1 , pp. 216-229
    • Varley, C.1    Hill, G.2    Pellegrin, S.3    Shaw, N.J.4    Selby, P.J.5    Trejdosiewicz, L.K.6    Southgate, J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.