Gestrinone inhibits growth of human uterine leiomyoma may relate to activity regulation of ERα, Src and P38 MAPK

Biomedicine and Pharmacotherapy

Volumn 66, Issue 8, 2012, Pages 569-577

  Zhu, Yan ^a   Zhang, Tingting ^b   Xie, Shuwu ^a   Tu, Ruiqin ^c   Cao, Yang ^b   Guo, Xiangjie ^a   Zhou, Jieyun ^a   Zhou, Xianying ^a   Cao, Lin ^a  

^a SHANGHAI INSTITUTE OF PLANNED PARENTHOOD RESEARCH   (China)

^b Shanghai Yueyang Hospital   (China)

^c FUDAN UNIVERSITY   (China)

Author keywords

C Src; ER ; Gestrinone; P38 MAPK; Uterine leiomyoma

Indexed keywords

ESTROGEN RECEPTOR ALPHA; GESTRINONE; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; PROTEIN TYROSINE KINASE;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE ARREST; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; FEMALE; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; NICK END LABELING; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UTERUS MYOMA; WESTERN BLOTTING;

APOPTOSIS; BLOTTING, WESTERN; CELL CULTURE TECHNIQUES; CELL CYCLE; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTROGEN RECEPTOR ALPHA; FEMALE; GESTRINONE; HUMANS; IN SITU NICK-END LABELING; LEIOMYOMA; MICROSCOPY, ELECTRON, TRANSMISSION; MOLECULAR STRUCTURE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; REAL-TIME POLYMERASE CHAIN REACTION; SRC-FAMILY KINASES; TIME FACTORS; TUMOR CELLS, CULTURED; UTERINE NEOPLASMS;

EID: 84869874128     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2012.02.003     Document Type: Article

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