Synthesis and antitumor activity of N-sulfonyl-3,7-dioxo-5β-cholan-24- amides, ursodeoxycholic acid derivatives

Steroids

Volumn 78, Issue 1, 2013, Pages 53-58

  Ren, Jie ^b   Wang, Yongchao ^a   Wang, Junliang ^a   Lin, Jun ^a   Wei, Kun ^a   Huang, Rong ^a  

^a YUNNAN UNIVERSITY   (China)

^b CHANGZHOU UNIVERSITY   (China)

Author keywords

Anti Tumour; N sulfonyl 3,7 dioxo 5 cholan 24 amides

Indexed keywords

3,7 DIOXO 24 AZIDO 5BETA CHOLAN; 3,7 DIOXO 24 CHOLAN METHANSULFONATE; 3,7 DIOXO 5BETA CHOLAN 24 AMIDE; 3,7 DIOXO 5BETA CHOLAN 24 OL; FLUOROURACIL; N (1' PHENYLMETHANESULFONYL) 3,7 DIOXO 5BETA CHOLAN 24 AMIDE; N (2' FLUOROBENZENESULFONYL) 3,7 DIOXO 5BETA CHOLAN 24 AMIDE; N (3' FLUOROBENZENESULFONYL) 3,7 DIOXO 5BETA CHOLAN 24 AMIDE; N (4' BROMOBENZENESULFONYL) 3,7 DIOXO 5BETA CHOLAN 24 AMIDE; N (4' CHLOROBENZENESULFONYL) 3,7 DIOXO 5BETA CHOLAN 24 AMIDE; N (4' FLUOROBENZENESULFONYL) 3,7 DIOXO 5BETA CHOLAN 24 AMIDE; N (4' METHYLBENZENESULFONYL) 3,7 DIOXO 5BETA CHOLAN 24 AMIDE; N (4' NITROBENZENESULFONYL) 3,7 DIOXO 5BETA CHOLAN 24 AMIDE; N (THIOPHENE 2 SULFONYL) 3,7 DIOXO 5BETA CHOLAN 24 AMIDE; N [4' (ACETAMIDE)BENZENESULFONYL] 3,7 DIOXO 5BETA CHOLAN 24 AMIDE; N [4' (TRIFLUOROMETHOXY)BENZENESULFONYL] 3,7 DIOXO 5BETA CHOLAN 24 AMIDE; N BENZENESULFONYL 3,7 DIOXO 5BETA CHOLAN 24 AMIDE; N ETHANESULFONYL 3,7 DIOXO 5BETA CHOLAN 24 AMIDE; N METHANESULFONYL 3,7 DIOXO 5BETA CHOLAN 24 AMIDE; N N BUTANESULFONYL 3,7 DIOXO 5BETA CHOLAN 24 AMIDE; N SULFONYL 3,7 DIOXO 5BETA CHOLAN 24 AMIDE; UNCLASSIFIED DRUG; URSODEOXYCHOLIC ACID; URSODEOXYCHOLIC ACID DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL STRAIN HCT116; CELL STRAIN K 562; CELL STRAIN MCF 7; CYTOTOXICITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; INHIBITORY CONCENTRATION 50; OXIDATION-REDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES; URSODEOXYCHOLIC ACID;

EID: 84869867603     PISSN: 0039128X     EISSN: 18785867     Source Type: Journal    
DOI: 10.1016/j.steroids.2012.09.009     Document Type: Article

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