Disclosure of a fundamental clue for the elucidation of the myricetin mechanism of action as amyloid aggregation inhibitor by mass spectrometry

Electrophoresis

Volumn 33, Issue 22, 2012, Pages 3380-3386

  Fiori, Jessica ^a   Naldi, Marina ^a   Bartolini, Manuela ^a   Andrisano, Vincenza ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Amyloid beta 1 42 aggregation; MALDI TOF; Myricetin; Nano LC ESI MS MS; Tryptic digest

Indexed keywords

FLAVONOIDS; GLYCOPROTEINS; MASS SPECTROMETRY; NEURODEGENERATIVE DISEASES; SELF ASSEMBLY;

AGGREGATION INHIBITORS; AMYLOID BETAS; AMYLOID-BETA 1-42 AGGREGATION; MALDI-TOF; MECHANISM OF ACTION; MYRICETIN; NANO-ESI; NANO-LC; NANO-LC-ESI-MS/MS; TRYPTIC DIGESTS;

MONOMERS;

AMYLOID BETA PROTEIN[1-42]; MONOMER; MYRICETIN;

AMINO ACID ANALYSIS; ARTICLE; CHEMICAL MODIFICATION; DRUG MECHANISM; DRUG SCREENING; ELECTROSPRAY IONISATION QUADRUPOLE TIME OF FLIGHT MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; OXIDATION REDUCTION STATE; PROTEIN AGGREGATION; PROTEIN ASSEMBLY; PROTEIN DETERMINATION;

EID: 84869817141     PISSN: 01730835     EISSN: 15222683     Source Type: Journal    
DOI: 10.1002/elps.201200186     Document Type: Article

References (20)

1. Naslund, J., Haroutunian, V., Mohs, R., Davis, K. L., Davies, P., Greengard, P., Bauxbaum, J. D., JAMA 2000, 283, 1571-1577.
2. Selkoe, D. J., J. Alzheimer's Dis. 2001, 3, 75-80.
3. Bartolini, M., Andrisano, V., Chembiochem. 2010, 11, 1018-1035.
4. Findeis, M. A., Pharmacol. Ther. 2007, 116, 266-286.
5. Ertekin-Taner, N., Graff-Radford, N., Younkin, L. H., Eckman, C., Baker, M., Adamson, J., Ronald, J., Blangero, J., Hutton, M., Younkin, S. G., Science 2000, 290, 2303-2304.
6. Bartolini, M., Naldi, M., Fiori, J., Valle, F., Biscarini, F., Nicolau, D. V., Andrisano, V., Anal. Biochem. 2011, 414, 215-225.
7. Bartolini, M., Bertucci, C., Bolognesi, M. L., Cavalli, A., Melchiorre, C., Andrisano, V., Chembiochem. 2007, 8, 2152-61.
8. Forester, S. C., Lambert, J., Mol. Nutr. Food Res. 2011, 55, 844-854.
9. Ono, K., Yoshiike, Y., Takashima, A., Hasegawa, K., Naiki, H., Yamada, M., J. Neurochem. 2003, 87, 172-181.
10. Hamaguchi, T., Ono, K., Murase, A., Yamada, M., Am. J. Pathol. 2009, 175, 2557-2565.
11. Shimmyo, Y., Kihara, T., Akaike, A., Niidome, T., Sugimoto, H., J. Neurosci. Res. 2008, 86, 368-377.
12. Necula, M., Kayed, R., Milton, S., Glabe, S. G., J. Biol. Chem. 2007, 282, 10311-10324.
13. Kuster, B., Mortensen, P., Andersen, J. S., Mann, M., Proteomics 2001, 1, 641-650.
14. Cheng, X., Van breemen, R. B., Anal. Chem. 2005, 77, 7012-7015.
15. Hou, L., Kang, I., Marchant, R. E., Zagorski, M. G., J. Biol. Chem. 2002, 277, 40173-40176.
16. Mochizuki, M., Yamazaki, S., Kano, K., Ikeda, T., Biochim. Biophys. Acta 2002, 1569, 35-44.
17. Bitan, G., Bogdan, T., Vollers S. S., Lashuel, H. A., Condron, M. M., Straub, J. E., Teplow, D. B., J. Am. Chem. Soc. 2003, 125, 15359-15365.
18. Varadarajan, S., Kanski, J., Aksenova, M., Lauderback, C. M., Butterfield, D. A., J. Am. Chem. Soc. 2001, 123, 5625-5631.
19. Butterfield, D. A., Kanski, J., Peptides 2002, 23, 1299-1309.
20. Schoneich, C., Arch. Biochem. Biophys. 2002, 397, 370-376.