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Volumn 280, Issue 1750, 2013, Pages

Evolution of a contagious cancer: Epigenetic variation in Devil Facial Tumour Disease

Author keywords

Cancer; DNA methylation; Epigenetic; Evolution; Marsupial; Tasmanian devil (Sarcophilus harrisii)

Indexed keywords

CANCER; ENZYME ACTIVITY; GENETIC ANALYSIS; HOMEOSTASIS; MARSUPIAL; METHYLATION; MUTATION; PHENOTYPIC PLASTICITY; TUMOR;

EID: 84869795645     PISSN: 09628452     EISSN: 14712954     Source Type: Journal    
DOI: 10.1098/rspb.2012.1720     Document Type: Article
Times cited : (17)

References (61)
  • 1
    • 56349163843 scopus 로고    scopus 로고
    • Lessons from the looming extinction of the Tasmanian devil
    • Lunney D, Jones M, McCallum H. 2008 Lessons from the looming extinction of the Tasmanian devil. Pac. Conserv. Biol. 14, 151-153.
    • (2008) Pac. Conserv. Biol. , vol.14 , pp. 151-153
    • Lunney, D.1    Jones, M.2    McCallum, H.3
  • 2
    • 35148823199 scopus 로고    scopus 로고
    • Conservation management of Tasmanian devils in the context of an emerging, extinction-threatening disease: Devil facial tumor disease
    • (doi:10.1007/ s10393-007-0120-6)
    • Jones ME et al. 2007 Conservation management of Tasmanian devils in the context of an emerging, extinction-threatening disease: devil facial tumor disease. EcoHealth 4, 326-337. (doi:10.1007/ s10393-007-0120-6)
    • (2007) EcoHealth , vol.4 , pp. 326-337
    • Jones, M.E.1
  • 3
    • 53649100391 scopus 로고    scopus 로고
    • Tasmanian devil facial tumour disease: Lessons for conservation biology
    • (doi:10.1016/j.tree. 2008.07.001)
    • McCallum H. 2008 Tasmanian devil facial tumour disease: lessons for conservation biology. Trends Ecol. Evol. 23, 631-637. (doi:10.1016/j.tree. 2008.07.001)
    • (2008) Trends Ecol. Evol. , vol.23 , pp. 631-637
    • McCallum, H.1
  • 4
    • 33744936007 scopus 로고    scopus 로고
    • Emerging disease and population decline of an island endemic, the Tasmanian devil Sarcophilus harrisii
    • (doi:10.1016/j.biocon.2006.04.010)
    • Hawkins CE et al. 2006 Emerging disease and population decline of an island endemic, the Tasmanian devil Sarcophilus harrisii. Biol. Conserv. 131, 307-324. (doi:10.1016/j.biocon.2006.04.010)
    • (2006) Biol. Conserv. , vol.131 , pp. 307-324
    • Hawkins, C.E.1
  • 6
    • 33751253421 scopus 로고    scopus 로고
    • The pathology of devil facial tumor disease (DFTD) in Tasmanian devils (Sarcophilus harrisii)
    • (doi:10.1354/vp.43-6-890)
    • Loh R, Bergfeld J, Hayes D, O'Hara A, Pyecroft S, Raidal S, Sharpe R. 2006 The pathology of devil facial tumor disease (DFTD) in Tasmanian devils (Sarcophilus harrisii). Vet. Pathol. 43, 890-895. (doi:10.1354/vp.43-6-890)
    • (2006) Vet. Pathol. , vol.43 , pp. 890-895
    • Loh, R.1    Bergfeld, J.2    Hayes, D.3    O'Hara, A.4    Pyecroft, S.5    Raidal, S.6    Sharpe, R.7
  • 7
    • 35148823198 scopus 로고    scopus 로고
    • Towards a case definition for devil facial tumour disease: What is it?
    • (doi:10.1007/s10393-007-0126-0)
    • Pyecroft SB et al. 2007 Towards a case definition for devil facial tumour disease: what is it? EcoHealth 4, 346-351. (doi:10.1007/s10393-007-0126-0)
    • (2007) EcoHealth , vol.4 , pp. 346-351
    • Pyecroft, S.B.1
  • 8
    • 31844442380 scopus 로고    scopus 로고
    • Allograft theory: Transmission of devil facial-tumour disease
    • (doi:10.1038/439549a)
    • Pearse AM, Swift K. 2006 Allograft theory: transmission of devil facial-tumour disease. Nature 439, 549. (doi:10.1038/439549a)
    • (2006) Nature , vol.439 , pp. 549
    • Pearse, A.M.1    Swift, K.2
  • 9
    • 62949200919 scopus 로고    scopus 로고
    • Research priorities in the Tasmanian devil facial tumour debate
    • Obendorf DL, McGlashan ND. 2008 Research priorities in the Tasmanian devil facial tumour debate. Eur. J. Oncol. 13, 229-238.
    • (2008) Eur. J. Oncol. , vol.13 , pp. 229-238
    • Obendorf, D.L.1    McGlashan, N.D.2
  • 10
    • 74949085550 scopus 로고    scopus 로고
    • The Tasmanian devil transcriptome reveals Schwann cell origins of a clonally transmissible cancer
    • (doi:10.1126/science.1180616)
    • Murchison EP et al. 2010 The Tasmanian devil transcriptome reveals Schwann cell origins of a clonally transmissible cancer. Science 327, 84-87. (doi:10.1126/science.1180616)
    • (2010) Science , vol.327 , pp. 84-87
    • Murchison, E.P.1
  • 11
    • 33751344783 scopus 로고    scopus 로고
    • The immunohistochemical characterization of devil facial tumor disease (DFTD) in the Tasmanian devil (Sarcophilus harrisii)
    • (doi:10.1354/vp.43-6-896)
    • Loh R, Hayes D, Mahjoor A, O'Hara A, Pyecroft S, Raidal S. 2006 The immunohistochemical characterization of devil facial tumor disease (DFTD) in the Tasmanian devil (Sarcophilus harrisii). Vet. Pathol. 43, 896-903. (doi:10.1354/vp.43-6-896)
    • (2006) Vet. Pathol. , vol.43 , pp. 896-903
    • Loh, R.1    Hayes, D.2    Mahjoor, A.3    O'Hara, A.4    Pyecroft, S.5    Raidal, S.6
  • 12
    • 79951551364 scopus 로고    scopus 로고
    • The role of the major histocompatibility complex in the spread of contagious cancers
    • (doi:10.1007/s00335-010-9294-2)
    • Belov K. 2011 The role of the major histocompatibility complex in the spread of contagious cancers. Mamm. Genome 22, 83-90. (doi:10.1007/s00335-010-9294-2)
    • (2011) Mamm. Genome , vol.22 , pp. 83-90
    • Belov, K.1
  • 13
    • 3242688188 scopus 로고    scopus 로고
    • Genetic diversity and population structure of Tasmanian devils, the largest marsupial carnivore
    • (doi:10.1111/j. 1365-294X.2004.02239.x)
    • Jones ME, Paetkau D, Geffen E, Moritz C. 2004 Genetic diversity and population structure of Tasmanian devils, the largest marsupial carnivore. Mol. Ecol. 13, 2197-2209. (doi:10.1111/j. 1365-294X.2004.02239.x)
    • (2004) Mol. Ecol. , vol.13 , pp. 2197-2209
    • Jones, M.E.1    Paetkau, D.2    Geffen, E.3    Moritz, C.4
  • 14
    • 36048990073 scopus 로고    scopus 로고
    • Transmission of a fatal clonal tumor by biting occurs due to depleted MHC diversity in a threatened carnivorous marsupial
    • (doi:10.1073/pnas.0704580104)
    • Siddle HV, Kreiss A, Eldridge MDB, Noonan E, Clarke CJ, Pyecroft S, Woods GM, Belov K. 2007 Transmission of a fatal clonal tumor by biting occurs due to depleted MHC diversity in a threatened carnivorous marsupial. Proc Natl Acad. Sci. USA 104, 16 221-16 226. (doi:10.1073/pnas.0704580104)
    • (2007) Proc Natl Acad. Sci. USA , vol.104 , pp. 16221-16226
    • Siddle, H.V.1    Kreiss, A.2    Eldridge, M.D.B.3    Noonan, E.4    Clarke, C.J.5    Pyecroft, S.6    Woods, G.M.7    Belov, K.8
  • 15
    • 77955355152 scopus 로고    scopus 로고
    • MHC gene copy number variation in Tasmanian devils: Implications for the spread of a contagious cancer
    • (doi:10.1098/rspb.2009.2362)
    • Siddle HV, Marzec J, Cheng Y, Jones M, Belov K. 2012 MHC gene copy number variation in Tasmanian devils: implications for the spread of a contagious cancer. Proc. R. Soc. B 277, 2001-2006. (doi:10.1098/rspb.2009.2362)
    • (2012) Proc. R. Soc. B , vol.277 , pp. 2001-2006
    • Siddle, H.V.1    Marzec, J.2    Cheng, Y.3    Jones, M.4    Belov, K.5
  • 16
    • 79961044560 scopus 로고    scopus 로고
    • Genetic diversity and population structure of the endangered marsupial Sarcophilus harrisii (Tasmanian devil)
    • (doi:10.1073/ pnas.1102838108)
    • Miller W et al. 2011 Genetic diversity and population structure of the endangered marsupial Sarcophilus harrisii (Tasmanian devil). Proc. Natl Acad. Sci. USA 198, 12 348-12 353. (doi:10.1073/ pnas.1102838108)
    • (2011) Proc. Natl Acad. Sci. USA , vol.198 , pp. 12348-12353
    • Miller, W.1
  • 17
    • 84863115547 scopus 로고    scopus 로고
    • Genome sequencing and analysis of the Tasmanian devil and its transmissible cancer
    • (doi:10.1016/j.cell.2011. 11.065)
    • Murchison EP et al. 2012 Genome sequencing and analysis of the Tasmanian devil and its transmissible cancer. Cell 148, 780-791. (doi:10.1016/j.cell.2011. 11.065)
    • (2012) Cell , vol.148 , pp. 780-791
    • Murchison, E.P.1
  • 18
    • 84859201448 scopus 로고    scopus 로고
    • Genomic restructuring in the Tasmanian devil facial tumour: Chromosome painting and gene mapping provide clues to evolution of a transmissible tumour
    • (doi:10.1371/journal.pgen.1002483)
    • Deakin JE et al. 2012 Genomic restructuring in the Tasmanian devil facial tumour: chromosome painting and gene mapping provide clues to evolution of a transmissible tumour. PLoS Genet. 8, e1002483. (doi:10.1371/journal.pgen.1002483)
    • (2012) PLoS Genet. , vol.8
    • Deakin, J.E.1
  • 19
    • 84860261981 scopus 로고    scopus 로고
    • Evolution in a transmissible cancer: A study of the chromosomal changes in devil facial tumor (DFT) as it spreads through the wild Tasmanian devil population
    • (doi:10.1016/j.cancergen.2011.12.001)
    • Pearse A-M, Swift K, Hodson P, Hua B, McCallum H, Pyecroft S, Taylor R, Eldridge MDB, Belov K. 2012 Evolution in a transmissible cancer: a study of the chromosomal changes in devil facial tumor (DFT) as it spreads through the wild Tasmanian devil population. Cancer Genet. 205, 101-112. (doi:10.1016/j.cancergen.2011.12.001)
    • (2012) Cancer Genet. , vol.205 , pp. 101-112
    • Pearse, A-M.1    Swift, K.2    Hodson, P.3    Hua, B.4    McCallum, H.5    Pyecroft, S.6    Taylor, R.7    Eldridge, M.D.B.8    Belov, K.9
  • 20
    • 36549056015 scopus 로고    scopus 로고
    • Epigenetic changes in cancer
    • (doi:10. 1111/j.1600-0463.2007.apm_636.xml.x)
    • Gronbaek K, Hother C, Jones PA. 2007 Epigenetic changes in cancer. APMIS 115, 1039-1059. (doi:10. 1111/j.1600-0463.2007.apm_636.xml.x)
    • (2007) APMIS , vol.115 , pp. 1039-1059
    • Gronbaek, K.1    Hother, C.2    Jones, P.A.3
  • 21
    • 54749102754 scopus 로고    scopus 로고
    • Cause and consequences of genetic and epigenetic alterations in human cancer
    • (doi:10.2174/ 138920208785699580)
    • Sadikovic B, Al-Romaih K, Squire JA, Zielenska M. 2012 Cause and consequences of genetic and epigenetic alterations in human cancer. Curr. Genom. 9, 394-408. (doi:10.2174/ 138920208785699580)
    • (2012) Curr. Genom. , vol.9 , pp. 394-408
    • Sadikovic, B.1    Al-Romaih, K.2    Squire, J.A.3    Zielenska, M.4
  • 22
    • 84957846754 scopus 로고
    • The quantitative separation of purines, pyrimidines, and nucleosides by paper chromatography
    • Hotchkiss RD. 1948 The quantitative separation of purines, pyrimidines, and nucleosides by paper chromatography. J. Biol. Chem. 175, 315-332.
    • (1948) J. Biol. Chem. , vol.175 , pp. 315-332
    • Hotchkiss, R.D.1
  • 23
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
    • (doi:10.1016/ s0092-8674(00)81656-6)
    • Okano M, Bell DW, Haber DA, Li E. 1999 DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99, 247-257. (doi:10.1016/ s0092-8674(00)81656-6)
    • (1999) Cell , vol.99 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3    Li, E.4
  • 24
    • 2542548558 scopus 로고
    • The purine and pyrimidine composition of deoxypentose nucleic acids
    • Wyatt GR. 1951 The purine and pyrimidine composition of deoxypentose nucleic acids. Biochem. J. 48, 584-590.
    • (1951) Biochem. J. , vol.48 , pp. 584-590
    • Wyatt, G.R.1
  • 25
    • 43749098985 scopus 로고    scopus 로고
    • DNA methylation landscapes: Provocative insights from epigenomics
    • (doi:10.1038/ nrg2341)
    • Suzuki MM, Bird A. 2008 DNA methylation landscapes: provocative insights from epigenomics. Nat. Rev. Genet. 9, 465-476. (doi:10.1038/ nrg2341)
    • (2008) Nat. Rev. Genet. , vol.9 , pp. 465-476
    • Suzuki, M.M.1    Bird, A.2
  • 26
    • 0345357773 scopus 로고    scopus 로고
    • Gene silencing in cancer in association with promoter hypermethylation
    • (doi:10.1056/NEJMra023075)
    • Herman JG, Baylin SB. 2003 Gene silencing in cancer in association with promoter hypermethylation. N. Engl. J. Med. 349, 2042-2054. (doi:10.1056/NEJMra023075)
    • (2003) N. Engl. J. Med. , vol.349 , pp. 2042-2054
    • Herman, J.G.1    Baylin, S.B.2
  • 27
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones PA, Baylin SB. 2002 The fundamental role of epigenetic events in cancer. Nat. Rev. Genet. 3, 415-428.
    • (2002) Nat. Rev. Genet. , vol.3 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 28
    • 9744251005 scopus 로고    scopus 로고
    • Biochemistry and biology of mammalian DNA methyltransferases
    • (doi:10.1007/ s00018-004-4201-1)
    • Hermann A, Gowher H, Jeltsch A. 2004 Biochemistry and biology of mammalian DNA methyltransferases. Cell. Mol. Life Sci. 61, 2571-2587. (doi:10.1007/ s00018-004-4201-1)
    • (2004) Cell. Mol. Life Sci. , vol.61 , pp. 2571-2587
    • Hermann, A.1    Gowher, H.2    Jeltsch, A.3
  • 29
    • 43049105333 scopus 로고    scopus 로고
    • Demethylation of (Cytosine-5-C-methyl) DNA and regulation of transcription in the epigenetic pathways of cancer development
    • (doi:10.1007/s10555-008-9118-y)
    • Patra S, Patra A, Rizzi F, Ghosh T, Bettuzzi S. 2012 Demethylation of (Cytosine-5-C-methyl) DNA and regulation of transcription in the epigenetic pathways of cancer development. Cancer Metastasis Rev. 27, 315-334. (doi:10.1007/s10555-008-9118-y)
    • (2012) Cancer Metastasis Rev. , vol.27 , pp. 315-334
    • Patra, S.1    Patra, A.2    Rizzi, F.3    Ghosh, T.4    Bettuzzi, S.5
  • 30
  • 31
    • 77956095231 scopus 로고    scopus 로고
    • Active DNA demethylation: Many roads lead to Rome
    • (doi:10.1038/nrm2950)
    • Wu SC, Zhang Y. 2010 Active DNA demethylation: many roads lead to Rome. Nat. Rev. Mol. Cell Biol. 11, 607-620. (doi:10.1038/nrm2950)
    • (2010) Nat. Rev. Mol. Cell Biol. , vol.11 , pp. 607-620
    • Wu, S.C.1    Zhang, Y.2
  • 32
    • 24344497413 scopus 로고    scopus 로고
    • Methyl-CpG binding proteins in the nervous system
    • (doi:10.1038/sj.cr.7290294)
    • Fan G, Hutnick L. 2005 Methyl-CpG binding proteins in the nervous system. Cell Res. 15, 255-261. (doi:10.1038/sj.cr.7290294)
    • (2005) Cell Res. , vol.15 , pp. 255-261
    • Fan, G.1    Hutnick, L.2
  • 33
    • 0035914262 scopus 로고    scopus 로고
    • Loss of expression of HDACrecruiting methyl-CpG-binding domain proteins in human cancer
    • (doi:10.1054/bjoc.2001.2041)
    • Muller-Tidow C. 2001 Loss of expression of HDACrecruiting methyl-CpG-binding domain proteins in human cancer. Br. J. Cancer 85, 1168-1174. (doi:10.1054/bjoc.2001.2041)
    • (2001) Br. J. Cancer , vol.85 , pp. 1168-1174
    • Muller-Tidow, C.1
  • 34
    • 0033575886 scopus 로고    scopus 로고
    • The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites
    • (doi:10.1038/45843)
    • Hendrich B, Hardeland U, Ng HH, Jiricny J, Bird A. 2012 The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites. Nature 401, 301-304. (doi:10.1038/45843)
    • (2012) Nature , vol.401 , pp. 301-304
    • Hendrich, B.1    Hardeland, U.2    Ng, H.H.3    Jiricny, J.4    Bird, A.5
  • 36
    • 0028834605 scopus 로고
    • AFLP: A new technique for DNA fingerprinting
    • (doi:10.1093/nar/23.21.4407)
    • Vos P et al. 1995 AFLP: a new technique for DNA fingerprinting. Nucleic Acids Res. 23, 4407-4414. (doi:10.1093/nar/23.21.4407)
    • (1995) Nucleic Acids Res. , vol.23 , pp. 4407-4414
    • Vos, P.1
  • 37
    • 0036006355 scopus 로고    scopus 로고
    • Amplified fragment length polymorphism analysis identifies hybrids between two subspecies of warblers
    • (doi:10.1046/j. 0962-1083.2001.01455.x)
    • Bensch S, Helbig AJ, Salomon M, Seibold I. 2002 Amplified fragment length polymorphism analysis identifies hybrids between two subspecies of warblers. Mol. Ecol. 11, 473-481. (doi:10.1046/j. 0962-1083.2001.01455.x)
    • (2002) Mol. Ecol. , vol.11 , pp. 473-481
    • Bensch, S.1    Helbig, A.J.2    Salomon, M.3    Seibold, I.4
  • 38
    • 0034558663 scopus 로고    scopus 로고
    • AFLP-based detection of DNA methylation
    • (doi:10.1007/BF02825064)
    • Xu M, Li X, Korban S. 2000 AFLP-based detection of DNA methylation. Plant Mol. Biol. Rep. 18, 361-368. (doi:10.1007/BF02825064)
    • (2000) Plant Mol. Biol. Rep. , vol.18 , pp. 361-368
    • Xu, M.1    Li, X.2    Korban, S.3
  • 39
    • 41449103243 scopus 로고    scopus 로고
    • DNA methylation is widespread across social Hymenoptera
    • (doi:10.1016/j.cub.2008.02.015)
    • Kronforst MR, Gilley DC, Strassmann JE, Queller DC. 2012 DNA methylation is widespread across social Hymenoptera. Curr. Biol. 18, R287-R288. (doi:10.1016/j.cub.2008.02.015)
    • (2012) Curr. Biol. , vol.18
    • Kronforst, M.R.1    Gilley, D.C.2    Strassmann, J.E.3    Queller, D.C.4
  • 40
    • 84859761838 scopus 로고    scopus 로고
    • DNA methylation in the termite Coptotermes lacteus
    • (doi:10.1007/s00040-011-0213-7)
    • Lo N, Li B, Ujvari B. 2012 DNA methylation in the termite Coptotermes lacteus. Insect Soc. 59, 257-261. (doi:10.1007/s00040-011-0213-7)
    • (2012) Insect Soc. , vol.59 , pp. 257-261
    • Lo, N.1    Li, B.2    Ujvari, B.3
  • 41
    • 0002129975 scopus 로고    scopus 로고
    • Quantification on the LightCycler instrument
    • eds S Meuer, C Wittwer, K Nakagawara, Heidelberg, Germany: Springer
    • Rasmussen R. 2001 Quantification on the LightCycler instrument. In Rapid cycle real-time PCR: methods and applications (eds S Meuer, C Wittwer, K Nakagawara), pp. 21-34. Heidelberg, Germany: Springer.
    • (2001) Rapid cycle real-time PCR: Methods and applications , pp. 21-34
    • Rasmussen, R.1
  • 42
    • 1842483281 scopus 로고    scopus 로고
    • Determination of stable housekeeping genes, differentially regulated target genes and sample integrity: BESTKEEPER-EXCEL-based tool using pairwise correlations
    • (doi:10.1023/B:BILE.0000019559.84305.47)
    • Pfaffl MW, Tichopad A, Prgomet C, Neuvians TP. 2012 Determination of stable housekeeping genes, differentially regulated target genes and sample integrity: BESTKEEPER-EXCEL-based tool using pairwise correlations. Biotechnol. Lett. 26, 509-515. (doi:10.1023/B:BILE.0000019559.84305.47)
    • (2012) Biotechnol. Lett. , vol.26 , pp. 509-515
    • Pfaffl, M.W.1    Tichopad, A.2    Prgomet, C.3    Neuvians, T.P.4
  • 43
    • 0036581160 scopus 로고    scopus 로고
    • Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR
    • (doi:10.1093/nar/30.9.e36)
    • Pfaffl MW, Horgan GW, Dempfle L. 2002 Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res. 30, e36. (doi:10.1093/nar/30.9.e36)
    • (2002) Nucleic Acids Res. , vol.30
    • Pfaffl, M.W.1    Horgan, G.W.2    Dempfle, L.3
  • 45
    • 0037068353 scopus 로고    scopus 로고
    • DNA methylation in cancer: Too much, but also too little
    • (doi:10.1038/sj.onc.1205651)
    • Ehrlich M. 2002 DNA methylation in cancer: too much, but also too little. Oncogene 21, 5400-5413. (doi:10.1038/sj.onc.1205651)
    • (2002) Oncogene , vol.21 , pp. 5400-5413
    • Ehrlich, M.1
  • 46
    • 66449131479 scopus 로고    scopus 로고
    • Hemimethylation footprints of DNA demethylation in cancer
    • (doi:10.4161/epi. 4.3.8277)
    • Shao C, Lacey M, Dubeau L, Ehrlich M. 2009 Hemimethylation footprints of DNA demethylation in cancer. Epigenetics 4, 165-175. (doi:10.4161/epi. 4.3.8277)
    • (2009) Epigenetics , vol.4 , pp. 165-175
    • Shao, C.1    Lacey, M.2    Dubeau, L.3    Ehrlich, M.4
  • 47
    • 55349130961 scopus 로고    scopus 로고
    • DNA hypomethylation arises later in prostate cancer progression than CpG Island hypermethylation and contributes to metastatic tumor heterogeneity
    • (doi:10.1158/0008-.can-07-6088)
    • Yegnasubramanian S et al. 2008 DNA hypomethylation arises later in prostate cancer progression than CpG Island hypermethylation and contributes to metastatic tumor heterogeneity. Cancer Res. 68, 8954-8967. (doi:10.1158/0008-.can-07-6088)
    • (2008) Cancer Res. , vol.68 , pp. 8954-8967
    • Yegnasubramanian, S.1
  • 48
    • 77955271952 scopus 로고    scopus 로고
    • LINE-1 retrotransposons: Mediators of somatic variation in neuronal genomes?
    • (doi:10. 1016/j.tins.2010.04.001)
    • Singer T, McConnell MJ, Marchetto MCN, Coufal NG, Gage FH. 2010 LINE-1 retrotransposons: mediators of somatic variation in neuronal genomes? Trends Neurosci. 33, 345-354. (doi:10. 1016/j.tins.2010.04.001)
    • (2010) Trends Neurosci. , vol.33 , pp. 345-354
    • Singer, T.1    McConnell, M.J.2    Marchetto, M.C.N.3    Coufal, N.G.4    Gage, F.H.5
  • 49
    • 20044379205 scopus 로고    scopus 로고
    • Constitutional aneuploidy in the normal human brain
    • (doi:10.1523/jneurosci.4560-04.2005)
    • Rehen SK et al. 2005 Constitutional aneuploidy in the normal human brain. J. Neurosci. 25, 2176-2180. (doi:10.1523/jneurosci.4560-04.2005)
    • (2005) J. Neurosci. , vol.25 , pp. 2176-2180
    • Rehen, S.K.1
  • 50
    • 33845243362 scopus 로고    scopus 로고
    • Cancer as an evolutionary and ecological process
    • (doi:10.1038/nrc2013)
    • Merlo LMF, Pepper JW, Reid BJ, Maley CC. 2006 Cancer as an evolutionary and ecological process. Nat. Rev. Cancer 6, 924-935. (doi:10.1038/nrc2013)
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 924-935
    • Merlo, L.M.F.1    Pepper, J.W.2    Reid, B.J.3    Maley, C.C.4
  • 51
    • 79952579323 scopus 로고    scopus 로고
    • Petos Paradox: Evolutions prescription for cancer prevention
    • (doi:10.1016/j.tree. 2011.01.002)
    • Caulin AF, Maley CC. 2011 Petos Paradox: evolutions prescription for cancer prevention. Trends Ecol. Evol. 26, 175-182. (doi:10.1016/j.tree. 2011.01.002)
    • (2011) Trends Ecol. Evol. , vol.26 , pp. 175-182
    • Caulin, A.F.1    Maley, C.C.2
  • 53
    • 62949136571 scopus 로고    scopus 로고
    • Devils of the alpine project: Field monitoring program
    • Coupland C, Anthony W. 2007 Devils of the alpine project: field monitoring program. Tasmanian Nat. 129, 65-81.
    • (2007) Tasmanian Nat. , vol.129 , pp. 65-81
    • Coupland, C.1    Anthony, W.2
  • 55
    • 84862010465 scopus 로고    scopus 로고
    • New insights into the role of MHC diversity in devil facial tumour disease
    • (doi:10.1371/journal. pone.0036955)
    • Lane A, Cheng Y, Wright B, Hamede R, Levan L, Jones M, Ujvari B, Belov K. 2012 New insights into the role of MHC diversity in devil facial tumour disease. PLoS ONE 7, e36955. (doi:10.1371/journal. pone.0036955)
    • (2012) PLoS ONE , vol.7
    • Lane, A.1    Cheng, Y.2    Wright, B.3    Hamede, R.4    Levan, L.5    Jones, M.6    Ujvari, B.7    Belov, K.8
  • 56
    • 0036281006 scopus 로고    scopus 로고
    • Effect of tumor infiltrating lymphocytes on the expression of MHC molecules in canine transmissible venereal tumor cells
    • (doi:10.1016/S0165-2427(02)00026-0)
    • Hsiao YW, Liao KW, Hung SW, Chu RM. 2002 Effect of tumor infiltrating lymphocytes on the expression of MHC molecules in canine transmissible venereal tumor cells. Vet. Immunol. Immunopathol. 87, 19-27. (doi:10.1016/S0165-2427(02)00026-0)
    • (2002) Vet. Immunol. Immunopathol. , vol.87 , pp. 19-27
    • Hsiao, Y.W.1    Liao, K.W.2    Hung, S.W.3    Chu, R.M.4
  • 57
    • 0142153985 scopus 로고    scopus 로고
    • DNA methylation and expression of major histocompatibility complex class I and class II transactivator genes in human developmental tumor cells and in T cell malignancies
    • (doi:10.1016/s1521-6616(03)00200-6)
    • van den Elsen PJ, Holling TM, van der Stoep N, Boss JM. 2003 DNA methylation and expression of major histocompatibility complex class I and class II transactivator genes in human developmental tumor cells and in T cell malignancies. Clin. Immunol. 109, 46-52. (doi:10.1016/s1521-6616(03)00200-6)
    • (2003) Clin. Immunol. , vol.109 , pp. 46-52
    • van den Elsen, P.J.1    Holling, T.M.2    van der Stoep, N.3    Boss, J.M.4
  • 58
    • 77950504048 scopus 로고    scopus 로고
    • Testing the theory of immune selection in cancers that break the rules of transplantation
    • (doi:10.1007/s00262-009-0809-1)
    • Fassati A, Mitchison N. 2010 Testing the theory of immune selection in cancers that break the rules of transplantation. Cancer Immunol. Immunother. 59, 643-651. (doi:10.1007/s00262-009-0809-1)
    • (2010) Cancer Immunol. Immunother. , vol.59 , pp. 643-651
    • Fassati, A.1    Mitchison, N.2
  • 59
    • 79960648995 scopus 로고    scopus 로고
    • Allorecognition in the Tasmanian devil (Sarcophilus harrisii), an endangered marsupial species with limited genetic diversity
    • (doi:10.1371/journal. pone.0022402)
    • Kreiss A, Cheng Y, Kimble F, Wells B, Donovan S, Belov K, Woods GM. 2011 Allorecognition in the Tasmanian devil (Sarcophilus harrisii), an endangered marsupial species with limited genetic diversity. PLoS ONE 6, e22402. (doi:10.1371/journal. pone.0022402)
    • (2011) PLoS ONE , vol.6
    • Kreiss, A.1    Cheng, Y.2    Kimble, F.3    Wells, B.4    Donovan, S.5    Belov, K.6    Woods, G.M.7
  • 61
    • 40849109768 scopus 로고    scopus 로고
    • Phenotypically concordant and discordant monozygotic twins display different DNA copy-number-variation profiles
    • (doi:10.1016/j. ajhg.2007.12.011)
    • Bruder CEG et al. 2008 Phenotypically concordant and discordant monozygotic twins display different DNA copy-number-variation profiles. Am. J. Hum. Genet. 82, 763-771. (doi:10.1016/j. ajhg.2007.12.011)
    • (2008) Am. J. Hum. Genet. , vol.82 , pp. 763-771
    • Bruder, C.E.G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.