MHC gene copy number variation in Tasmanian devils: Implications for the spread of a contagious cancer

Proceedings of the Royal Society B: Biological Sciences

Volumn 277, Issue 1690, 2010, Pages 2001-2006

  Siddle, Hannah V ^a   Marzec, Jolanta ^a   Cheng, Yuanyuan ^a   Jones, Menna ^b   Belov, Katherine ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF TASMANIA   (Australia)

Author keywords

Cancer; Devil facial tumour disease; Marsupial; MHC; Tasmanian devil

Indexed keywords

ALLELE; ANTIGEN; CANCER; DISEASE SPREAD; ENDANGERED SPECIES; EXTINCTION; GENETIC DIFFERENTIATION; IMMUNE SYSTEM; MARSUPIAL; POPULATION STRUCTURE; TUMOR;

EID: 77955355152     PISSN: 09628452     EISSN: 14712970     Source Type: Journal    
DOI: 10.1098/rspb.2009.2362     Document Type: Article

References (38)

1. Amadou, C., Kumanovics, A., Jones, E. P., LambrachtWashington, D., Yoshino, M. & Lindahl, K. F. 1999 The mouse major histocompatibility complex: some assembly required. Immunol. Rev. 167, 211-221. (doi:10.1111/j.l600-065X.1999.tb01394.x) (Pubitemid 29178983)
2. Birch, J., Murphy, L., MacHugh, N. D. & Ellis, S. A. 2006 Generation and maintenance of diversity in the cattle MHC Class I region. Immunogenetics 58, 670-679. (doi: 10.1007/S00251-006-0137-y) (Pubitemid 44100414)
3. Cho, P. S. et al. 2007 Establishment of transplantable porcine tumour cell lines derived from MHC inbred miniature swine. Blood 110, 3996-4004. (doi:10.1182/blood2007-02-074450)
4. DPIW 2008 Save the Tasmanian devil. See http://www.dpiw. tas.gov.au/inter.nsf/WebPages/LBUN-SQF86?open.
5. Guiler, E. 1985 Thylacine: the tragedy of the Tasmanian tiger. Melbourne, Australia: Oxford University Press.
6. Guiler, E. 1992 The Tasmanian devil. Hobart, Tasmania: St. Davids Park Publishing.
7. Guiler, E. R. & Godard, P. 1998 Tasmanian Tiger: a lesson to be learnt. Perth, Australia: Abrolhos Publishing Pty Ltd.
8. Hedrick, P. W., Parker, K. M., Gutierrez-Espeleta, G. A., Rattink, A. & Lievers, K. 2000 Major histocompatibility complex variation in the Arabian oryx. Evolution 54, 2145-2151. (Pubitemid 32113840)
9. Holland, O. J., Cowan, P. E., Gleeson, D. M. & Chamley, L. W. 2008 High variability in the MHC Class II DA β chain of the brushtail possum (Trichosurus vulpecula).Immunogenetics 60, 775-781. (10.1007/s00251-008-0327-x)
10. Hughes, A. L. 1991 MHC polymorphism and the design of captive breeding programs. Conserv. Biol. 5, 249-251. (doi:10.1111/j.l523-1739.1991.tb00130.x)
11. Hughes, A. & Nei, M. 1988 Pattern of nucleotide substitution at the major histocompatibility complex Class I loci reveals overdominant selection. Nature 335, 167-170. (doi: 10.1038/335167a0)
12. Hughes, A. L. & Nei, M. 1992 Maintenance of MHC polymorphism. Nature 355, 402-403. (doi:10.1038/ 355402b0)
13. Jones, M. E., Paetkau, D., Geffen, E. & Moritz, C. 2004 Genetic diversity and population structure of Tasmanian devils, the largest marsupial carnivore. Mol. Ecol. 13, 2197-2209. (doi:10.1111/j.1365-294X.2004. 02239.x) (Pubitemid 38946410)
14. Kreiss, A., Fox, N., Bergfeld, J., Quinn, S. J., Pyecroft, S. & Woods, G. M. 2008 Assessment of cellular immune responses of healthy and diseased Tasmanian devils (Sarcophilus harrisii). Dev. Comp. Immunol. 32, 544-553. (doi:10.1016/j.dci.2007.09.002)
15. Kumar, S., Tamura, K. & Nei, M. 2004 MEGA3: integrated software for molecular evolutionary genetics analysis and sequence alignment. Brief Bioinform. 5, 150-163. (doi:10.1093/bib/5.2.150)
16. Lachish, S., Jones, M. & McCallum, H. 2007 The impact of disease on the survival and population growth rate of the Tasmanian devil. J. Anim. Ecol. 76, 926-936. (doi: 10. 1111/J.1365-2656.2007.01272.X)
17. Loh, R., Bergfeld, J., Hayes, D., O'Hara, A., Pyecroft, S., Raidal, S. & Sharpe, R. 2006a The pathology of devil facial tumor disease (DFTD) in Tasmanian devils (Sarcophilus harrisii). Vet. Pathol. 43, 890-895. (doi:10. 1354/vp.43-6-890)
18. Loh, R., Hayes, D., Mahjoor, A., O'Hara, A., Pyecroft, S. & Raidal, S. 2006b The immunohistochemical characterization of devil facial tumor disease (DFTD) in the Tasmanian devil (Sarcophilus harrisii). Vet. Pathol. 43, 896-903. (doi:10.1354/vp.43-6-896) (Pubitemid 44801381)
19. McCallum, H. & Jones, M. 2006 To lose both would look like carelessness: Tasmanian devil facial tumour disease. PLoS Biol. 4, e342. (doi:10.1371/journal.pbio. 0040342)
20. McCallum, H., Tompkins, D. M., Jones, M. E., Lachish, S., Marvenek, S., Lazenby, B., Hocking, G. J., Wiersma, J. & Hawkins, C. 2007 Distribution and impacts of Tasmanian devil facial tumour disease. EcoHealth 4, 318-325. (doi:10.1007/s10393-007-0118-0) (Pubitemid 47547117)
21. Meyer-Lucht, Y., Otten, C., Puttker, T & Sommer, S. 2008 Selection, diversity and evolutionary patterns of the MHC Class II DAB in free-ranging Neotropical marsupials. BMC Genet. 9, 39-53. (doi:10.1186/1471-2156-9-39)
22. Miller, P. S. 1995 Selective breeding programs for rare alleles: examples from the przewalski horse and California condor pedigrees. Conserv. Biol. 9, 1262-1273. (Pubitemid 3000874)
23. Miller, H. C., Andrews-Cookson, M. & Daugherty, C. H. 2007 Two patterns of variation among MHC Class I loci in Tuatara (Sphenodon punctatus). J. Hered. 98, 666-677. (doi: 10.1093/jhered/esm095)
24. Miska, K. B. & Miller, R. D. 1999 Marsupial MHC Class I: classical sequences from the opossum, Monodelphisdomestica. Immunogenetics 50, 89-93. (doi: 10.1007/ S002510050692)
25. O'Brien, S. & Evermann, J. 1988 Interactive influence of infectious disease and genetic diversity in natural populations. Trends Ecol. Evol. 3, 254-259.
26. Otting, N., Heijmans, C. M., Noort, R. C., de Groot, N. G., Doxiadis, G. G., Van Rood, J. J., Watkins, D. I. & Bontrop, R. E. 2005 Unparalleled complexity of the MHC Class I region in rhesus macaques. Proc. Natl Acad. Sci. USA 102, 1626-1631. (doi:10.1073/pnas. 0409084102)
27. Pearse, A. M. & Swift, K. 2006 Allograft theory: transmission of devil facial tumour disease. Nature 439, 549. (doi:10.1038/439549a) (Pubitemid 43185372)
28. Pyecroft, S. B. et al. 2007 Towards a case definition for devil facial tumor disease: what is it? EcoHealth 4, 346-351. (doi: 10.1007/s 10393-007-0126-0)
29. Roos, C. & Walter, L. 2005 Considerable haplotypic diversity in the RTl-CE Class I gene region of the rat major histocompatibility complex. Immunogenetics 56, 773-777. (doi: 10.1007/s00251-004-0744-4) (Pubitemid 40174974)
30. Sanford, B. H., Codingto, J. F, Jeanloz, R. W. & Palmer, P. D. 1973 Transplantability and antigenicity of 2 sublines of Ta3 tumor. J. Immunol. 110, 1233-1237.
31. Siddle, H. V., Deakin, J. E., Baker, M. L., Miller, R. D. & Belov, K. 2006 Isolation of major histocompatibility complex Class I genes from the tammar wallaby (Macropus eugenii). Immunogenetics 58, 487-493. (doi: 10.1007/ s00251-006-0107-4)
32. Siddle, H. V., Kreiss, A., Eldridge, M. D., Noonan, E., Clarke, C. J., Pyecroft, S., Woods, G. M. & Belov, K. 2007a Transmission of a fatal clonal tumor by biting occurs due to depleted MHC diversity in a threatened carnivorous marsupial. Proc. Natl Acad. Sci. USA 104, 16 221-16 226. (doi:10.1073/pnas. 0704580104)
33. Siddle, H. V., Sanderson, C. & Belov, K. 2007b Characterization of major histocompatibility complex Class I and Class II genes from the Tasmanian devil (Sarcophilus harrisii). Immunogenetics 59, 753-760. (doi:10.1007/s00251- 007-0238-2) (Pubitemid 47415564)
34. Siddle, H. V., Deakin, J. E., Coggill, P., Hart, E., Cheng, Y., Wong, E. S., Harrow, J., Beck, S. & Belov, K. 2009 MHC-linked and un-linked Class I genes in the wallaby. BMC Genom. 10, 310-325. (doi:10.1186/1471-2164-10-310)
35. Slade, R. W. 1992 Limited MHC polymorphism in the southern elephant seal: implications for MHC evolution and marine mammal population biology. Proc. R. Soc. Lond. B 249, 163-171. (doi:10.1098/rspb.1992.0099)
36. Stone, W. H., Manis, G. S., Hoffman, E. S., Saphire, D. G., Hubbard, G. B. & VandeBerg, J. L. 1997 Fate of allogeneic skin transplantations in a marsupial (Monodelphis domestica). Lab. Anim. Sci. 47, 283-287.
37. Tanaka-Matsuda, M., Ando, A., Rogel-Gaillard, C., Chardon, P. & Uenishi, H. 2009 Difference in number of loci of swine leukocyte antigen classical Class I genes among haplotypes. Genomics 93, 261-273. (doi: 10. 1016/j.ygeno.2008.10.004)
38. Woods, G. M., Kreiss, A., Belov, K., Siddle, H. V., Obendorf, D. L. & Muller, H. K. 2007 The immune response of the Tasmanian devil (Sarcophilus harrisii) and devil facial tumour disease. EcoHealth 4, 338-345. (doi:10.1007/s10393-007-0117-1) (Pubitemid 47547116)