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Volumn 48, Issue 18, 2012, Pages 3465-3474

Gemcitabine causes telomere attrition by stabilizing TRF2

Author keywords

Gemcitabine; Telomere; TRF2

Indexed keywords

EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; GEMCITABINE; PROTEIN; TELOMERIC REPEAT BINDING FACTOR 2; UNCLASSIFIED DRUG; XERODERMA PIGMENTOSUM GROUP F PROTEIN;

EID: 84869500777     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2012.04.015     Document Type: Article
Times cited : (10)

References (31)
  • 1
    • 0036311866 scopus 로고    scopus 로고
    • Gemcitabine and targeted therapy in metastatic breast cancer
    • G. Qu, and E.A. Perez Gemcitabine and targeted therapy in metastatic breast cancer Semin Oncol 29 3 Suppl. 11 2002 44 52 (Pubitemid 34816065)
    • (2002) Seminars in Oncology , vol.29 , Issue.3 SUPPL. 11 , pp. 44-52
    • Qu, G.1    Perez, E.A.2
  • 2
    • 0036314481 scopus 로고    scopus 로고
    • Gemcitabine induction chemotherapy in non-small cell lung cancer
    • A. Depierre, V. Westeel, and P. Jacoulet Gemcitabine induction chemotherapy in non-small cell lung cancer Semin Oncol 29 3 Suppl. 9 2002 55 60 (Pubitemid 34753286)
    • (2002) Seminars in Oncology , vol.29 , Issue.3 SUPPL. 9 , pp. 55-60
    • Depierre, A.1    Westeel, V.2    Jacoulet, P.3
  • 3
    • 0036314025 scopus 로고    scopus 로고
    • Present and future treatment of pancreatic cancer
    • V. Heinemann Present and future treatment of pancreatic cancer Semin Oncol 29 3 Suppl. 9 2002 23 31 (Pubitemid 34753280)
    • (2002) Seminars in Oncology , vol.29 , Issue.3 SUPPL. 9 , pp. 23-31
    • Heinemann, V.1
  • 5
    • 0034327360 scopus 로고    scopus 로고
    • Equilibrative-sensitive nucleoside transporter and its role in gemcitabine sensitivity
    • D.R. Rauchwerger, P.S. Firby, D.W. Hedley, and M.J. Moore Equilibrative-sensitive nucleoside transporter and its role in gemcitabine sensitivity Cancer Res 60 2000 6075 6079
    • (2000) Cancer Res , vol.60 , pp. 6075-6079
    • Rauchwerger, D.R.1    Firby, P.S.2    Hedley, D.W.3    Moore, M.J.4
  • 7
    • 0028105119 scopus 로고
    • Schedule dependence of sensitivity to 2′, 2′- difluorodeoxycytidine (Gemcitabine) in relation to accumulation and retention of its triphosphate in solid tumour cell lines and solid tumours
    • V.W. Ruiz van Haperen, G. Veerman, and E. Boven Schedule dependence of sensitivity to 2′, 2′-difluorodeoxycytidine (Gemcitabine) in relation to accumulation and retention of its triphosphate in solid tumour cell lines and solid tumours Biochem Pharmacol 48 1994 1327 1339
    • (1994) Biochem Pharmacol , vol.48 , pp. 1327-1339
    • Ruiz Van Haperen, V.W.1    Veerman, G.2    Boven, E.3
  • 8
    • 0028832342 scopus 로고
    • Gemcitabine: A modulator of intracellular nucleotide and deoxynucleotide metabolism
    • V. Heinemann, L. Schulz, R.D. Issels, and W. Plunkett Gemcitabine: A modulator of intracellular nucleotide and deoxynucleotide metabolism Semin Oncol 22 4 Suppl. 11 1995 11 18
    • (1995) Semin Oncol , vol.22 , Issue.4 SUPPL. 11 , pp. 11-18
    • Heinemann, V.1    Schulz, L.2    Issels, R.D.3    Plunkett, W.4
  • 9
    • 0026571795 scopus 로고
    • Cellular elimination of 2′,2′-difluorodeoxycytidine 5′-triphosphate: A mechanism of self-potentiation
    • V. Heinemann, Y.Z. Xu, and S. Chubb Cellular elimination of 2′,2′-difluorodeoxycytidine 5′-triphosphate: A mechanism of self-potentiation Cancer Res 52 1992 533 539
    • (1992) Cancer Res , vol.52 , pp. 533-539
    • Heinemann, V.1    Xu, Y.Z.2    Chubb, S.3
  • 10
    • 0025737572 scopus 로고
    • 2′-Deoxy-2′-methylenecytidine and 2′-deoxy-2′, 2′-difluorocytidine 5′-diphosphates: Potent mechanism-based inhibitors of ribonucleotide reductase
    • C.H. Baker, J. Banzon, and J.M. Bollinger 2′-Deoxy-2′- methylenecytidine and 2′-deoxy-2′, 2′-difluorocytidine 5′-diphosphates: potent mechanism-based inhibitors of ribonucleotide reductase J Med Chem 34 1991 1879 1884
    • (1991) J Med Chem , vol.34 , pp. 1879-1884
    • Baker, C.H.1    Banzon, J.2    Bollinger, J.M.3
  • 11
    • 0029563009 scopus 로고
    • Telomeres: Beginning to understand the end
    • V.A. Zakian Telomeres: beginning to understand the end Science 270 1995 1601 1607 (Pubitemid 26002435)
    • (1995) Science , vol.270 , Issue.5242 , pp. 1601-1607
    • Zakian, V.A.1
  • 12
    • 0025731583 scopus 로고
    • Structure and function of telomeres
    • E.H. Blackburn Structure and function of telomeres Nature 350 1991 569 573 (Pubitemid 21912269)
    • (1991) Nature , vol.350 , Issue.6319 , pp. 569-573
    • Blackburn, E.H.1
  • 13
    • 0013462065 scopus 로고
    • A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes
    • R.K. Moyzis, J.M. Buckingham, and L.S. Cram A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes Proc Natl Acad Sci U S A 85 1988 6622 6626
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 6622-6626
    • Moyzis, R.K.1    Buckingham, J.M.2    Cram, L.S.3
  • 15
    • 0024788528 scopus 로고
    • Structure and function of telomeres
    • V.A. Zakian Structure and function of telomeres Annu Rev Genet 23 1989 579 604 (Pubitemid 20033416)
    • (1989) Annual Review of Genetics , vol.23 , pp. 579-604
    • Zakian, V.A.1
  • 16
    • 0025115349 scopus 로고
    • Structure and variability of human chromosome ends
    • T. de Lange, L. Shiue, and R.M. Myers Structure and variability of human chromosome ends Mol Cell Biol 10 1990 518 527
    • (1990) Mol Cell Biol , vol.10 , pp. 518-527
    • De Lange, T.1    Shiue, L.2    Myers, R.M.3
  • 17
    • 0024325562 scopus 로고
    • The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats
    • DOI 10.1016/0092-8674(89)90035-4
    • G.B. Morin The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats Cell 59 1989 521 529 (Pubitemid 19284465)
    • (1989) Cell , vol.59 , Issue.3 , pp. 521-529
    • Morin, G.B.1
  • 18
    • 0026523228 scopus 로고
    • Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
    • C.M. Counter, A.A. Avilion, and C.E. LeFeuvre Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity EMBO J 11 1992 1921 1929
    • (1992) EMBO J , vol.11 , pp. 1921-1929
    • Counter, C.M.1    Avilion, A.A.2    Lefeuvre, C.E.3
  • 19
    • 0028564951 scopus 로고
    • Specific association of human telomerase activity with immortal cells and cancer
    • N.W. Kim, M.A. Piatyszek, and K.R. Prowse Specific association of human telomerase activity with immortal cells and cancer Science 266 1994 2011 2015
    • (1994) Science , vol.266 , pp. 2011-2015
    • Kim, N.W.1    Piatyszek, M.A.2    Prowse, K.R.3
  • 20
    • 84993876589 scopus 로고
    • Correlating telomerase activity levels with human neuroblastoma outcomes
    • E. Hiyama, K. Hiyama, and T. Yokoyama Correlating telomerase activity levels with human neuroblastoma outcomes Nat Med 1 1995 249 255
    • (1995) Nat Med , vol.1 , pp. 249-255
    • Hiyama, E.1    Hiyama, K.2    Yokoyama, T.3
  • 22
    • 0032531003 scopus 로고    scopus 로고
    • Close correlation between telomerase expression and adenomatous polyp progression in multistep colorectal carcinogenesis
    • R. Tang, A.J. Cheng, J.Y. Wang, and T.C. Wang Close correlation between telomerase expression and adenomatous polyp progression in multistep colorectal carcinogenesis Cancer Res 58 1998 4052 4054 (Pubitemid 28440553)
    • (1998) Cancer Research , vol.58 , Issue.18 , pp. 4052-4054
    • Tang, R.1    Cheng, A.-J.2    Wang, J.-Y.3    Wang, T.-C.V.4
  • 23
    • 6944241531 scopus 로고    scopus 로고
    • Telomere biology: A new player in the end zone
    • C. Colgin, and R. Reddel Telomere biology: A new player in the end zone Current Biology 14 2004 R901 R902
    • (2004) Current Biology , vol.14
    • Colgin, C.1    Reddel, R.2
  • 25
    • 2042429168 scopus 로고    scopus 로고
    • Regulation of telomerase by telomeric proteins
    • DOI 10.1146/annurev.biochem.73.071403.160049
    • A. Smogorzewska, and T. de Lange Regulation of telomerase by telomeric proteins Annu Rev Biochem 73 2004 177 208 (Pubitemid 39050367)
    • (2004) Annual Review of Biochemistry , vol.73 , pp. 177-208
    • Smogorzewska, A.1    De Lange, T.2
  • 27
    • 77954520138 scopus 로고    scopus 로고
    • Population pharmacokinetics of gemcitabine and its metabolite in Japanese cancer patients: Impact of genetic polymorphisms
    • E. Sugiyama, N. Kaniwa, and S.R. Kim Population pharmacokinetics of gemcitabine and its metabolite in Japanese cancer patients: impact of genetic polymorphisms J Clin Pharmacokinet 49 2010 549 558
    • (2010) J Clin Pharmacokinet , vol.49 , pp. 549-558
    • Sugiyama, E.1    Kaniwa, N.2    Kim, S.R.3
  • 28
    • 27144515686 scopus 로고    scopus 로고
    • XPF nuclease-dependent telomere loss and increased DNA damage in mice overexpressing TRF2 result in premature aging and cancer
    • DOI 10.1038/ng1633, PII N1633
    • P. Muñoz, R. Blanco, J.M. Flores, and M.A. Blasco XPF nuclease-dependent telomere loss and increased DNA damage in mice overexpressing TRF2 result in premature aging and cancer Nat Genet 37 2005 1063 1071 (Pubitemid 41486658)
    • (2005) Nature Genetics , vol.37 , Issue.10 , pp. 1063-1071
    • Munoz, P.1    Blanco, R.2    Flores, J.M.3    Blasco, M.A.4
  • 29
    • 33745288539 scopus 로고    scopus 로고
    • TERF2-XPF: Caught in the middle; beginnings from the end
    • DOI 10.1016/j.dnarep.2006.03.012, PII S1568786406001443
    • L.D. McDaniel, R.A. Schultz, and E.C. Friedberg TERF2-XPF: caught in the middle; beginnings from the end DNA Repair (Amst) 5 2006 868 872 (Pubitemid 43928892)
    • (2006) DNA Repair , vol.5 , Issue.7 , pp. 868-872
    • McDaniel, L.D.1    Schultz, R.A.2    Friedberg, E.C.3
  • 30
    • 33846517601 scopus 로고    scopus 로고
    • Telomerase abrogation dramatically accelerates TRF2-induced epithelial carcinogenesis
    • DOI 10.1101/gad.406207
    • R. Blanco, P. Muñoz, J.M. Flores, P. Klatt, and M.A. Blasco Telomerase abrogation dramatically accelerates TRF2-induced epithelial carcinogenesis Genes Dev 21 2007 206 220 (Pubitemid 46155814)
    • (2007) Genes and Development , vol.21 , Issue.2 , pp. 206-220
    • Blanco, R.1    Munoz, P.2    Flores, J.M.3    Klatt, P.4    Blasco, M.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.