Effect of purified β-glucans derived from Laminaria digitata, Laminaria hyperborea and Saccharomyces cerevisiae on piglet performance, selected bacterial populations, volatile fatty acids and pro-inflammatory cytokines in the gastrointestinal tract of pigs

British Journal of Nutrition

Volumn 108, Issue 7, 2012, Pages 1226-1234

  Sweeney, T ^a   Collins, C B ^a   Reilly, P ^a   Pierce, K M ^a   Ryan, M ^a   O'Doherty, J V ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

Glucans; Microbiota; Pigs; Pro inflammatory cytokines

Indexed keywords

BETA GLUCAN; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 1ALPHA; INTERLEUKIN 8; TUMOR NECROSIS FACTOR ALPHA; VOLATILE FATTY ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENTEROBACTERIACEAE; FATTY ACID SYNTHESIS; FOOD INTAKE; GASTROINTESTINAL TRACT; GENE EXPRESSION PROFILING; INTERLEUKIN 10 GENE; INTERLEUKIN 17A GENE; INTERLEUKIN 1ALPHA GENE; INTERLEUKIN 8 GENE; LAMINARIA; LAMINARIA DIGITATA; LAMINARIA HYPERBOREA; NONHUMAN; PIGLET; SACCHAROMYCES CEREVISIAE; TUMOR NECROSIS FACTOR ALPHA GENE; WEIGHT GAIN;

ANIMAL FEED; ANIMALS; BETA-GLUCANS; BIFIDOBACTERIUM; COLON; CYTOKINES; ENTEROBACTERIACEAE; FATTY ACIDS, VOLATILE; GENE EXPRESSION PROFILING; ILEUM; LACTOBACILLUS; LAMINARIA; LIPOPOLYSACCHARIDES; LOWER GASTROINTESTINAL TRACT; MICROBIAL VIABILITY; PREBIOTICS; SACCHAROMYCES CEREVISIAE; SOLUBILITY; SUS SCROFA; WEIGHT GAIN;

ANIMALIA; BACTERIA (MICROORGANISMS); ENTEROBACTERIACEAE; LAMINARIA DIGITATA; LAMINARIA HYPERBOREA; SACCHAROMYCES CEREVISIAE; SUIDAE;

EID: 84869478038     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114511006751     Document Type: Article

References (39)

1. Pluske JR, Hampson DJ & Williams IH (1997) Factors influencing the structure and function of the small intestine in the weaned pig. Livest Prod Sci 51, 215-236. (Pubitemid 127395778)
2. Hampson DJ (1986) Attempts to modify changes in the piglet small intestine after weaning. Res Vet Sci 40, 313-317.
3. Williams BA, Verstegen MWA & Tamminga S (2001) Fermentation in the large intestine of single stomached animals and its relationship to human health. Nut Res Rev 14, 207-227. (Pubitemid 34044758)
4. Hahn TW, Lohakare JD, Lee SL, et al. (2006) Effects of supplementation of b-glucans on growth performance, nutrient digestibility, and immunity in weanling pigs. J Anim Sci 84, 1422-1428. (Pubitemid 43844894)
5. Reilly P, O'Doherty JV, Pierce KM, et al. (2011) The effects of seaweed extract inclusion on gut morphology, selected intestinal microbiota, nutrient digestibility, volatile fatty acid concentrations and the immune status of the weaned pig. Animal 2, 1465-1473.
6. Smith AG, O'Doherty JV, Reilly P, et al. (2011) The effects of laminarin derived from Laminaria digitata on measurements of gut health: selected bacterial populations, intestinal fermentation, mucin gene expression and cytokine gene expression in the pig. Br J Nutr 105, 669-677.
7. MacArtain P, Gill CIR, Brooks M, et al. (2007) Nutritional value of edible seaweeds. Nutr Rev 65, 535-543. (Pubitemid 351804335)
8. Brown GD & Gordon S (2005) Immune recognition of fungal b-glucans. Cell Microbiol 7, 471-479.
9. Read SM, Currie G & Bacic A (1996) Analysis of the structural heterogeneity of laminarian by electrospray-ionisation-mass spectrometry. Carbohydr Res 281, 187-201. (Pubitemid 26070012)
10. Manners DJ, Masson AJ & Patterson JC (1973) The structure of a b-(1 ! 3)-D-glucan from yeast cell walls. Biochem J 135, 19-30.
11. Gahan DA, Lynch MB, Callan JJ, et al. (2009) Performance of weanling piglets offered low-, medium-or high-lactose diets supplemented with a seaweed extract from Laminaria spp. Animal 3, 24-31.
12. McDonnell P, Figat S & O'Doherty JV (2010) The effect of dietary laminarin and fucoidan in the diet of the weanling piglet on performance, selected faecal microbial populations and volatile fatty acid concentrations. Animal 4, 579-585.
13. Li J, Li DF, Xing JJ, et al. (2006) Effects of b-glucan extracted from Saccharomyces cerevisiae on growth performance, and immunological and somatotropic responses of pigs challenged with Escherichia coli lipopolysaccharide. J Anim Sci 84, 2374-2381. (Pubitemid 44367862)
14. Lynch MB, Sweeney T, Callan JJ, et al. (2010) The effect of dietary Laminaria-derived laminarin and fucoidan on nutrient digestibility, nitrogen utilisation, intestinal microflora and volatile fatty acid concentration in pigs. J Sci Food Agric 90, 430-437.
15. Friedlaender MHG, Cook WH & Martin WG (1954) Molecular weight and hydrodynamic properties of laminarin. Biochim Biophys Acta 14, 136-144.
16. Close WH (1994) Feeding new genotypes: establishing amino acid/energy requirements. In Principles of Pig Science, pp. 123-140 [DJA Cole, J Wiseman and MA Varley, editors]. Loughborough: Nottingham University Press.
17. Pierce KM, Sweeney T, Brophy PO, et al. (2005) Dietary manipulation post weaning to improve piglet performance and gastro-intestinal health. Anim Sci 81, 347-356. (Pubitemid 43067138)
18. Pierce KM, Sweeney T, Brophy PO, et al. (2006) The effect of lactose and inulin on intestinal morphology, selected microbial populations and volatile fatty acid concentrations in the gastro-intestinal tract of the weanling pig. Anim Sci 82, 311-318.
19. Ryan MT, Collins CB, O'Doherty JV, et al. (2010) Selection of stable reference genes for quantitative real-time PCR in porcine gastrointestinal tissues. Livest Sci 133, 42-44.
20. Vandesompele J, De Preter K, Pattyn F, et al. (2002) Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 3, research 0034.1-0034.11.
21. Statistical Analysis Systems Institute (1985) Statistical Analysis Systems, version 6.12. Cary, NC: SAS Institute, Inc.
22. Gardiner GE, Campbell AJ, O'Doherty JV, et al. (2008) Effect of Ascophyllum nodosum extract on growth performance, digestibility, carcass characteristics and selected intestinal microflora populations of grower-finisher pigs. Anim Feed Sci Technol 141, 259-273. (Pubitemid 351296379)
23. Muralidhara KS, Sheggeby GG, Elliker PR, et al. (1977) Effect of feeding lactobacilli on the coliform and Lactobacillus flora of intestinal tissue and feces from piglets. J Food Prot 40, 288-295.
24. Jørgensen L, Hansen CF & Kjærsgaard H, et al. (2002) Particle Size in Meal Feed to Slaughter Pigs. Effects on Productivity, Salmonella prevalence, and the Gastrointestinal Ecosystem Publication No. 580. The National Commitee for Pig Production, Copenhagen, Denmark
25. Mikkelsen LL, Naughton PJ, Hedemann MS, et al. (2004) Effects of physical properties of feed on microbial ecology and survival of Salmonella enterica serovar Typhimurium in the pig gastrointestinal tract. Appl Environ Microbiol 70, 3485-3492. (Pubitemid 38745894)
26. Leser TD, Amenuvor JZ, Jensen TK, et al. (2002) Cultureindependent analysis of gut bacteria: the pig gastrointestinal tract microbiota revisited. Appl Environ Microbiol 68, 673-690. (Pubitemid 34113056)
27. Macfarlane S & Macfarlane GT (2003) Regulation of shortchain fatty acid production. Proc Nutr Soc 62, 67-72.
28. Deville C, Damas J, Forget P, et al. (2004) Laminarin in the dietary fibre concept. J Sci Food Agric 84, 1030-1038. (Pubitemid 38852127)
29. Marounek M, Adamec T, Skrivanová V, et al. (2002) Nitrogen and in vitro fermentation of nitrogenous substrates in caecal contents of the pig. Acta Vet Brno 71, 429-433. (Pubitemid 36369072)
30. Ahern PP, Izcue A, Maloy KJ, et al. (2008) The interleukin-23 axis in intestinal inflammation. Immunol Rev 226, 147-159.
31. Ivanov Frutos II, Rde L, Manel N, et al. (2008) Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine. Cell Host Microbe 4, 337-349.
32. Maslowski KM & Mackay CR (2011) Diet, gut microbiota and immune responses. Nat Immunol 12, 5-9.
33. Russell JB, Sniffen CJ & Van Soest PJ (1983) Effect of carbohydrate limitation on degradation and utilization of casein by mixed rumen bacteria. J Dairy Sci 66, 763-775.
34. Aumaitre A, Peiniau J & Madec F (1995) Digestive adaptation after weaning and nutritional consequences in the piglet. Pig News Inf 16, 73N-79N.
35. Bhattacharyya S, Gill R, Chen ML, et al. (2008) Toll-like receptor 4 mediates induction of the Bc110-NFkB-interleukin-8 inflammatory pathway by carrageenan in human intestinal epithelial cells. J Biol Chem 283, 10550-10558.
36. Barton B (1996) The biological effects of interleukin 6. Med Res Rev 16, 87-109. (Pubitemid 26034189)
37. Reilly P, Sweeney T, O'Shea C, et al. (2010) The effect of cereal-derived beta-glucans and exogenous enzyme supplementation on intestinal microflora, nutrient digestibility, mineral metabolism and volatile fatty acid concentrations in finisher pigs. Anim Food Sci Technol 158, 165-176.
38. Brennan CS & Cleary LJ (2005) The potential use of cereal (1-3, 1-4)-b-D-glucans as functional food ingredients. J Cereal Sci 42, 1-13. (Pubitemid 40717556)
39. Sauvant D, Perez JM & Tran G (2004) Tables of Composition and Nutritional Value of Feed Materials: Pigs, Poultry, Cattle, Sheep, Goats, Rabbits, Horses, Fish. Wageningen, Netherlands and INRA Versailles: Wageningen Academic Publishers.