Top-down approach for the direct characterization of low molecular weight heparins using LC-FT-MS

Analytical Chemistry

Volumn 84, Issue 20, 2012, Pages 8822-8829

  Li, Lingyun ^a   Zhang, Fuming ^b   Zaia, Joseph ^d   Linhardt, Robert J ^a,b,c  

^a Research Rensselaer Polytechnic Institute   (United States)

^b RENSSELAER POLYTECHNIC INSTITUTE   (United States)

^c RENSSELAER POLYTECHNIC INSTITUTE   (United States)

^d BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANALYTICAL TECHNOLOGY; BIOINFORMATICS SOFTWARE; BIOLOGICAL SAMPLES; CHROMATOGRAPHIC SEPARATIONS; GLYCOMICS; HYDROPHILIC INTERACTION CHROMATOGRAPHY; ION-PAIRING CHROMATOGRAPHY; IONIZATION EFFICIENCY; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; LOW-MOLECULAR WEIGHT HEPARINS; MASS ACCURACY; METABOLOMICS; MOBILE PHASE; POLYDISPERSES; PROTEOMICS; REVERSED PHASE; SAMPLE PREPARATION; SIZE EXCLUSION; STRUCTURAL COMPLEXITY; TOP-DOWN APPROACH; TOPDOWN;

ACETONITRILE; AMIDES; BIOINFORMATICS; CHARACTERIZATION; CHROMATOGRAPHY; CROSSLINKING; ELECTROSPRAY IONIZATION; HIGH PRESSURE LIQUID CHROMATOGRAPHY; IONIZATION; MOLECULAR BIOLOGY; ORGANIC POLYMERS;

POLYSACCHARIDES;

ANTICOAGULANT AGENT; ENOXAPARIN; LOW MOLECULAR WEIGHT HEPARIN;

ANIMAL; ARTICLE; BIOLOGY; CARBOHYDRATE ANALYSIS; CHEMICAL PHENOMENA; COMPUTER PROGRAM; ELECTROSPRAY MASS SPECTROMETRY; FOURIER ANALYSIS; LIQUID CHROMATOGRAPHY; METHODOLOGY; MOLECULAR GENETICS; SWINE;

ANIMALS; ANTICOAGULANTS; CARBOHYDRATE SEQUENCE; CHROMATOGRAPHY, LIQUID; COMPUTATIONAL BIOLOGY; ENOXAPARIN; FOURIER ANALYSIS; HEPARIN, LOW-MOLECULAR-WEIGHT; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MOLECULAR SEQUENCE DATA; SOFTWARE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SWINE;

EID: 84869411674     PISSN: 00032700     EISSN: 15206882     Source Type: Journal    
DOI: 10.1021/ac302232c     Document Type: Article

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