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Volumn 4, Issue , 2011, Pages 439-465

Heparin characterization: Challenges and solutions

Author keywords

CE; cITP; HPLC; mass spectrometry; microcoil; NMR; SEC

Indexed keywords

ASSEMBLY PROCESS; BOTTOM UP APPROACH; CITP; COMPONENT OLIGOSACCHARIDES; ENZYMATIC REACTION; EPIMERS; GLYCOSAMINOGLYCANS; HEPARAN SULFATES; HEXASACCHARIDES; HPLC; MICROCOILS; MICROHETEROGENEITY; MOLECULAR LEVELS; SEC; SENSITIVE MASS; SIZE POLYDISPERSITY; URONIC ACIDS;

EID: 79959526692     PISSN: 19361327     EISSN: 19361335     Source Type: Book Series    
DOI: 10.1146/annurev-anchem-061010-113911     Document Type: Review
Times cited : (88)

References (128)
  • 1
    • 56649100319 scopus 로고    scopus 로고
    • The structure of glycosaminoglycans and their interactions with proteins
    • Gandhi NS, Mancera RL. 2008. The structure of glycosaminoglycans and their interactions with proteins. Chem. Biol. Drug Des. 72:455-82
    • (2008) Chem. Biol. Drug Des. , vol.72 , pp. 455-82
    • Gandhi, N.S.1    Mancera, R.L.2
  • 2
    • 0035984272 scopus 로고    scopus 로고
    • Heparin and heparan sulfate: Structure and function
    • DOI 10.1039/b100916h
    • Rabenstein DL. 2002. Heparin and heparan sulfate: structure and function. Nat. Prod. Rep. 19:312-31 (Pubitemid 34656777)
    • (2002) Natural Product Reports , vol.19 , Issue.3 , pp. 312-331
    • Rabenstein, D.L.1
  • 3
    • 0038792320 scopus 로고    scopus 로고
    • 2003 Claude S. Hudson award address in carbohydrate chemistry. Heparin: Structure and activity
    • DOI 10.1021/jm030176m
    • Linhardt RJ. 2003. 2003 Claude S. Hudson Award address in carbohydrate chemistry. Heparin: structure and activity. J. Med. Chem. 46:2551-64 (Pubitemid 36702523)
    • (2003) Journal of Medicinal Chemistry , vol.46 , Issue.13 , pp. 2551-2564
    • Linhardt, R.J.1
  • 5
    • 0033959545 scopus 로고    scopus 로고
    • Heparan sulfate proteoglycans on the cell surface: Versatile coordinators of cellular functions
    • DOI 10.1016/S1357-2725(99)00116-8, PII S1357272599001168
    • Tumova S, Woods A, Couchman JR. 2000. Heparan sulfate proteoglycans on the cell surface: versatile coordinators of cellular functions. Int. J. Biochem. Cell Biol. 32:269-88 (Pubitemid 30069970)
    • (2000) International Journal of Biochemistry and Cell Biology , vol.32 , Issue.3 , pp. 269-288
    • Tumova, S.1    Woods, A.2    Couchman, J.R.3
  • 7
    • 0028851033 scopus 로고
    • Expression of the heparin-binding cytokines, midkine (MK) and HB-GAM (pleiotrophin) is associated with epithelialmesenchymal interactions during fetal development and organogenesis
    • Mitsiadis TA, Salmivirta M, Muramatsu T, Muramatsu H, Rauvala H, et al. 1995. Expression of the heparin-binding cytokines, midkine (MK) and HB-GAM (pleiotrophin) is associated with epithelialmesenchymal interactions during fetal development and organogenesis. Development 121:37-51
    • (1995) Development , vol.121 , pp. 37-51
    • Mitsiadis, T.A.1    Salmivirta, M.2    Muramatsu, T.3    Muramatsu, H.4    Rauvala, H.5
  • 8
    • 73949157671 scopus 로고    scopus 로고
    • Differential interactions of FGFs with heparan sulfate control gradient formation and branching morphogenesis
    • Makarenkova HP, Hoffman MP, Beenken A, Eliseenkova AV, Meech R, et al. 2009. Differential interactions of FGFs with heparan sulfate control gradient formation and branching morphogenesis. Sci. Signal. 2:ra55
    • (2009) Sci. Signal. , vol.2
    • Makarenkova, H.P.1    Hoffman, M.P.2    Beenken, A.3    Eliseenkova, A.V.4    Meech, R.5
  • 9
    • 0034904186 scopus 로고    scopus 로고
    • Heparan sulfate proteoglycans: Heavy hitters in the angiogenesis arena
    • DOI 10.1172/JCI200113738
    • Iozzo RV, San Antonio JD. 2001. Heparan sulfate proteoglycans: heavy hitters in the angiogenesis arena. J. Clin. Microbiol. 108:349-55 (Pubitemid 32730778)
    • (2001) Journal of Clinical Investigation , vol.108 , Issue.3 , pp. 349-355
    • Iozzo, R.V.1    San Antonio, J.D.2
  • 10
    • 50449111339 scopus 로고    scopus 로고
    • Glycosaminoglycan-binding cytokines as tumor markers
    • Muramatsu T, Muramatsu H. 2008. Glycosaminoglycan-binding cytokines as tumor markers. Proteomics 8:3350-59
    • (2008) Proteomics , vol.8 , pp. 3350-59
    • Muramatsu, T.1    Muramatsu, H.2
  • 11
    • 0035168796 scopus 로고    scopus 로고
    • Proteoglycans of the extracellular matrix and growth control
    • DOI 10.1002/jcp.10030
    • Kresse H, Schönherr E. 2001. Proteoglycans of the extracellular matrix and growth control. J. Cell. Physiol. 189:266-74 (Pubitemid 33063294)
    • (2001) Journal of Cellular Physiology , vol.189 , Issue.3 , pp. 266-274
    • Kresse, H.1    Schnherr, E.2
  • 12
    • 0031650702 scopus 로고    scopus 로고
    • Bio-specific sequences and domains in heparan sulphate and the regulation of cell growth and adhesion
    • DOI 10.1016/S0945-053X(98)90096-8
    • Lyon M, Gallagher JT. 1998. Bio-specific sequences and domains in heparan sulphate and the regulation of cell growth and adhesion. Matrix Biol. 17:485-93 (Pubitemid 28566883)
    • (1998) Matrix Biology , vol.17 , Issue.7 , pp. 485-493
    • Lyon, M.1    Gallagher, J.T.2
  • 13
    • 70449604674 scopus 로고    scopus 로고
    • Heparin, heparan sulfate and heparanase in inflammatory reactions
    • Li J-P, Vlodavsk I. 2009. Heparin, heparan sulfate and heparanase in inflammatory reactions. Thromb. Haemost. 102:823-28
    • (2009) Thromb. Haemost. , vol.102 , pp. 823-28
    • Li, J.-P.1    Vlodavsk, I.2
  • 14
    • 17444419693 scopus 로고    scopus 로고
    • Sugar codes for axons?
    • DOI 10.1016/j.neuron.2005.03.021
    • Holt CE, Dickson BJ. 2005. Sugar codes for axons? Neuron 46:169-72 (Pubitemid 40545773)
    • (2005) Neuron , vol.46 , Issue.2 , pp. 169-172
    • Holt, C.E.1    Dickson, B.J.2
  • 15
    • 0037704306 scopus 로고    scopus 로고
    • Extracellular matrix molecules and synaptic plasticity
    • DOI 10.1038/nrn1115
    • Dityatev A, Schachner M. 2003. Extracellular matrix molecules and synaptic plasticity. Nat. Rev. Neurosci. 4:456-68 (Pubitemid 37280167)
    • (2003) Nature Reviews Neuroscience , vol.4 , Issue.6 , pp. 456-468
    • Dityatev, A.1    Schachner, M.2
  • 16
    • 54149096721 scopus 로고    scopus 로고
    • Heparan sulfates from arteries and veins differ in their antithrombin-mediated anticoagulant activity
    • De Mattos DA, Stelling MP, Tovar AMF, Mourao PAS. 2008. Heparan sulfates from arteries and veins differ in their antithrombin-mediated anticoagulant activity. J. Thromb. Haemost. 6:1987-90
    • (2008) J. Thromb. Haemost. , vol.6 , pp. 1987-90
    • De Mattos, D.A.1    Stelling, M.P.2    Amf, T.3    Pas, M.4
  • 17
    • 0029027169 scopus 로고
    • Binding of syndecan-like cell surface proteoglycan receptors is required for Neisseria gonorrhoeae entry into human mucosal cells
    • Van Putten JPM, Paul SM. 1995. Binding of syndecan-like cell surface proteoglycan receptors is required for Neisseria gonorrhoeae entry into human mucosal cells. EMBO J. 14:2144-54
    • (1995) EMBO J. , vol.14 , pp. 2144-54
    • Van Putten Jpm1    Paul, S.M.2
  • 18
    • 0031023713 scopus 로고    scopus 로고
    • Microbial adherence to and invasion through proteoglycans
    • Rostand KS, Esko JD. 1997. Microbial adherence to and invasion through proteoglycans. Infect. Immun. 65:1-8 (Pubitemid 27008896)
    • (1997) Infection and Immunity , vol.65 , Issue.1 , pp. 1-8
    • Rostand, K.S.1    Esko, J.D.2
  • 19
    • 77953076127 scopus 로고    scopus 로고
    • Proteoglycans in host-pathogen interactions: Molecular mechanisms and therapeutic implications
    • Bartlett AH, Park PW. 2010. Proteoglycans in host-pathogen interactions: molecular mechanisms and therapeutic implications. Expert Rev. Mol. Med. 12:e5
    • (2010) Expert Rev. Mol. Med. , vol.12
    • Bartlett, A.H.1    Park, P.W.2
  • 20
    • 0029049674 scopus 로고
    • Low molecular weight heparin(s)
    • Barrowcliffe TW. 1995. Low molecular weight heparin(s). Br. J. Haematol. 90:1-7
    • (1995) Br. J. Haematol. , vol.90 , pp. 1-7
    • Barrowcliffe, T.W.1
  • 22
    • 79251612095 scopus 로고    scopus 로고
    • Analysis and characterization of heparin impurities
    • Beni S, Limtiaco JFK, Larive CK. 2011. Analysis and characterization of heparin impurities. Anal. Bioanal. Chem. 399:517-39
    • (2011) Anal. Bioanal. Chem. , vol.399 , pp. 517-39
    • Beni, S.1    Jfk, L.2    Larive, C.K.3
  • 24
    • 79251610234 scopus 로고    scopus 로고
    • Applications of isotopes in advancing structural and functional heparanomics
    • Tran V, Nguyen T, Raman K, Kuberan B. 2011. Applications of isotopes in advancing structural and functional heparanomics. Anal. Bioanal. Chem. 399:559-70
    • (2011) Anal. Bioanal. Chem. , vol.399 , pp. 559-70
    • Tran, V.1    Nguyen, T.2    Raman, K.3    Kuberan, B.4
  • 25
    • 79251643168 scopus 로고    scopus 로고
    • Hyphenated techniques for the analysis of heparin and heparan sulfate
    • Yang B, Solakyildrim K, Chang Y, Linhardt RJ. 2011. Hyphenated techniques for the analysis of heparin and heparan sulfate. Anal. Bioanal. Chem. 399:541-57
    • (2011) Anal. Bioanal. Chem. , vol.399 , pp. 541-57
    • Yang, B.1    Solakyildrim, K.2    Chang, Y.3    Linhardt, R.J.4
  • 26
    • 79959492943 scopus 로고    scopus 로고
    • Glycoaminoglycans: Oligosaccharide analysis by liquid chromatography/specific labeling
    • In press
    • Langesley DJ, Jones CJ, Beni S, Larive CK. 2011. Glycoaminoglycans: oligosaccharide analysis by liquid chromatography/specific labeling. Methods Mol. Biol. In press
    • (2011) Methods Mol. Biol.
    • Langesley, D.J.1    Jones, C.J.2    Beni, S.3    Larive, C.K.4
  • 27
    • 0028363168 scopus 로고
    • Action pattern of polysaccharide lyases on glycosaminoglycans
    • Jandik KA, Gu KA, Linhardt RJ. 1994. Action pattern of polysaccharide lyases on glycosaminoglycans. Glycobiology 4:289-96 (Pubitemid 24217245)
    • (1994) Glycobiology , vol.4 , Issue.3 , pp. 289-296
    • Jandik, K.A.1    Gu, K.2    Linhardt, R.J.3
  • 28
    • 0027236273 scopus 로고
    • Specificity studies on the heparin lyases from Flavobacterium heparinum
    • Desai UR, Wang HM, Linhardt RJ. 1993. Specificity studies on the heparin lyases from flavobacterium heparinum. Biochemistry 32:8140-45 (Pubitemid 23265801)
    • (1993) Biochemistry , vol.32 , Issue.32 , pp. 8140-8145
    • Desai, U.R.1    Wang, H.-M.2    Linhardt, R.J.3
  • 30
    • 0017189425 scopus 로고
    • Formation of anhydrosugars in chemical depolymerization of heparin
    • Shively JE, Conrad HE. 1976. Formation of anhydrosugars in chemical depolymerization of heparin. Biochemistry 15:3932-42
    • (1976) Biochemistry , vol.15 , pp. 3932-42
    • Shively, J.E.1    Conrad, H.E.2
  • 32
    • 77749254954 scopus 로고    scopus 로고
    • Low-molecular-weight heparin from Cu2+ and Fe2+ Fenton type depolymerisation processes
    • Vismara E, Pierini M, Mascellani G, Liverani L, Lima M, et al. 2010. Low-molecular-weight heparin from Cu2+ and Fe2+ Fenton type depolymerisation processes. Thromb. Haemost. 103:613-22
    • (2010) Thromb. Haemost. , vol.103 , pp. 613-22
    • Vismara, E.1    Pierini, M.2    Mascellani, G.3    Liverani, L.4    Lima, M.5
  • 34
    • 0031952152 scopus 로고    scopus 로고
    • Disaccharide analysis of heparin and heparan sulfate using deaminative cleavage with nitrous acid and subsequent labeling with paranitrophenyl hydrazine
    • Kariya Y, Herrmann J, Suzuki K, Isomura T, Ishihara M. 1998. Disaccharide analysis of heparin and heparan sulfate using deaminative cleavage with nitrous acid and subsequent labeling with paranitrophenyl hydrazine. J. Biochem. 123:240-46 (Pubitemid 28120756)
    • (1998) Journal of Biochemistry , vol.123 , Issue.2 , pp. 240-246
    • Kariya, Y.1    Herrmann, J.2    Suzuki, K.3    Isomura, T.4    Ishihara, M.5
  • 35
    • 0021913331 scopus 로고
    • Structural characterization of the oligosaccharides formed by depolymerization of heparin with nitrous acid
    • Bienkowski MJ, Conrad HE. 1985. Structural characterization of the oligosaccharides formed by depolymerization of heparin with nitrous acid. J. Biol. Chem. 260:356-65 (Pubitemid 15164059)
    • (1985) Journal of Biological Chemistry , vol.260 , Issue.1 , pp. 356-365
    • Bienkowski, M.J.1    Conrad, H.E.2
  • 37
    • 25144521846 scopus 로고    scopus 로고
    • Quantification of isomers from a mixture of twelve heparin and heparan sulfate disaccharides using tandem mass spectrometry
    • DOI 10.1002/rcm.2079
    • Behr JR, Matsumoto Y, White FM, Sasisekharan R. 2005. Quantification of isomers from a mixture of twelve heparin and heparan sulfate disaccharides using tandem mass spectrometry. Rapid Commun. Mass Spectrom. 19:2553-62 (Pubitemid 41338597)
    • (2005) Rapid Communications in Mass Spectrometry , vol.19 , Issue.18 , pp. 2553-2562
    • Behr, J.R.1    Matsumoto, Y.2    White, F.M.3    Sasisekharan, R.4
  • 38
    • 33947407183 scopus 로고    scopus 로고
    • Quantitative determination of disaccharide content in digested unfragmented heparin and low molecular weight heparin by direct-infusion electrospray mass spectrometry
    • DOI 10.1016/j.jpba.2007.01.006, PII S0731708507000271
    • Camara JE, Satterfield MB, Nelson BC. 2007. Quantitative determination of disaccharide content in digested unfragmented heparin and low molecular weight heparin by direct-infusion electrospray mass spectrometry. J. Pharm. Biomed. Anal. 43:1706-14 (Pubitemid 46453090)
    • (2007) Journal of Pharmaceutical and Biomedical Analysis , vol.43 , Issue.5 , pp. 1706-1714
    • Camara, J.E.1    Satterfield, M.B.2    Nelson, B.C.3
  • 39
    • 25144469685 scopus 로고    scopus 로고
    • Compositional profiling of heparin/heparan sulfate using mass spectrometry: Assay for specificity of a novel extracellular human endosulfatase
    • Saad OM, Ebel H, Uchimura K, Rosen SD, Bertozzi CR, Leary JA. 2005. Compositional profiling of heparin/heparan sulfate using mass spectrometry: assay for specificity of a novel extracellular human endosulfatase. Glycobiology 15:812-26
    • (2005) Glycobiology , vol.15 , pp. 812-26
    • Saad, O.M.1    Ebel, H.2    Uchimura, K.3    Rosen, S.D.4    Bertozzi, C.R.5    Leary, J.A.6
  • 40
    • 0038677409 scopus 로고    scopus 로고
    • Compositional analysis and quantification of heparin and heparan sulfate by electrospray ionization ion trap mass spectrometry
    • DOI 10.1021/ac0340455
    • Saad OM, Leary JA. 2003. Compositional analysis and quantification of heparin and heparan sulfate by electrospray ionization ion trap mass spectrometry. Anal. Chem. 75:2985-95 (Pubitemid 36830424)
    • (2003) Analytical Chemistry , vol.75 , Issue.13 , pp. 2985-2995
    • Saad, O.M.1    Leary, J.A.2
  • 41
    • 0035850796 scopus 로고    scopus 로고
    • Chromatographic methods for product-profile analysis and isolation of oligosaccharides produced by heparinase-catalyzed depolymerization of heparin
    • DOI 10.1016/S0021-9673(01)01241-9, PII S0021967301012419
    • Chuang W-L, McAllister H, Rabenstein DL. 2001. Chromatographicmethods for product-profile analysis and isolation of oligosaccharides produced by heparinase-catalyzed depolymerization of heparin. J. Chromatogr. A 932:65-74 (Pubitemid 32938187)
    • (2001) Journal of Chromatography A , vol.932 , Issue.1-2 , pp. 65-74
    • Chuang, W.-L.1    McAllister, H.2    Rabenstein, D.L.3
  • 44
    • 9144223196 scopus 로고    scopus 로고
    • On-line size-exclusion chromatography/mass spectrometry of low molecular mass heparin
    • DOI 10.1002/jms.723
    • Henriksen J, Ringborg LH, Roepstorrf P. 2004. On-line size-exclusion chromatography/mass spectrometry of low molecular mass heparin. J. Mass Spectrom. 39:1305-12 (Pubitemid 39545980)
    • (2004) Journal of Mass Spectrometry , vol.39 , Issue.11 , pp. 1305-1312
    • Henriksen, J.1    Ringborg, L.H.2    Roepstorrf, P.3
  • 45
    • 34250351975 scopus 로고    scopus 로고
    • Nonspecific electrostatic binding characteristics of the heparin-antithrombin interaction
    • DOI 10.1002/bip.20731
    • Seyrek E, Dubin PL, Henriksen J. 2007. Nonspecific electrostatic binding characteristics of the heparinantithrombin interaction. Biopolymers 86:249-59 (Pubitemid 46910396)
    • (2007) Biopolymers , vol.86 , Issue.3 , pp. 249-259
    • Seyrek, E.1    Dubin, P.L.2    Henriksen, J.3
  • 46
    • 0035863643 scopus 로고    scopus 로고
    • Compositional analysis of glycosaminoglycans by electrospray mass spectrometry
    • DOI 10.1021/ac000777a
    • Zaia J, Costello CE. 2001. Compositional analysis of glycosaminoglycans by electrospray mass spectrometry. Anal. Chem. 73:233-39 (Pubitemid 32061834)
    • (2001) Analytical Chemistry , vol.73 , Issue.2 , pp. 233-239
    • Zaia, J.1    Costello, C.E.2
  • 47
    • 33745399299 scopus 로고    scopus 로고
    • Overview on advances in capillary electrophoresis-mass spectrometry of carbohydrates: A tabulated review
    • DOI 10.1002/elps.200500960
    • Campa C, Coslovi A, Flamigni A, Rossi M. 2006. Overview on advances in capillary electrophoresis-mass spectrometry of carbohydrates: a tabulated review. Electrophoresis 27:2027-50 (Pubitemid 43942106)
    • (2006) Electrophoresis , vol.27 , Issue.11 , pp. 2027-2050
    • Campa, C.1    Coslovi, A.2    Flamigni, A.3    Rossi, M.4
  • 48
    • 0029996036 scopus 로고    scopus 로고
    • Recent advances in capillary electrophoresis of carbohydrates
    • DOI 10.1002/elps.1150170203
    • El Rassi Z, Mechref Y. 1996. Recent advances in capillary electrophoresis of carbohydrates. Electrophoresis 17:275-301 (Pubitemid 26089116)
    • (1996) Electrophoresis , vol.17 , Issue.2 , pp. 275-301
    • El Rassi, Z.1    Mechref, Y.2
  • 49
    • 0142157732 scopus 로고    scopus 로고
    • Capillary electrophoretic separation of heparin oligosaccharides under conditions amenable to mass spectrometric detection
    • DOI 10.1016/S0021-9673(03)01288-3
    • Gunay NS, Linhardt RJ. 2003. Capillary electrophoretic separation of heparin oligosaccharides under conditions amenable to mass spectrometric detection. J. Chromatogr. A 1014:225-33 (Pubitemid 37311174)
    • (2003) Journal of Chromatography A , vol.1014 , Issue.1-2 , pp. 225-233
    • Gunay, N.S.1    Linhardt, R.J.2
  • 50
    • 0032545378 scopus 로고    scopus 로고
    • Use of reversed polarity and a pressure gradient in the analysis of disaccharide composition of heparin by capillary electrophoresis
    • DOI 10.1016/S0021-9673(98)00662-1, PII S0021967398006621
    • Ruiz-Calero V, Puignou L, Galceran MT. 1998. Use of reversed polarity and a pressure gradient in the analysis of disaccharide composition of heparin by capillary electrophoresis. J. Chromatogr. A 828:497-508 (Pubitemid 29046451)
    • (1998) Journal of Chromatography A , vol.828 , Issue.1-2 , pp. 497-508
    • Ruiz-Calero, V.1    Puignou, L.2    Galceran, M.T.3
  • 51
    • 36749074927 scopus 로고    scopus 로고
    • A simple capillary electrophoresis method for the rapid separation and determination of intact low molecular weight and unfractionated heparins
    • DOI 10.1016/j.jpba.2007.10.009, PII S0731708507005742
    • Patel RP, Narkowicz C, Hutchinson JP, Hilder EF, Jacobson GA. 2008. A simple capillary electrophoresis method for the rapid separation and determination of intact low molecular weight and unfractionated heparins. J. Pharm. Biomed. Anal. 46:30-35 (Pubitemid 350216339)
    • (2008) Journal of Pharmaceutical and Biomedical Analysis , vol.46 , Issue.1 , pp. 30-35
    • Patel, R.P.1    Narkowicz, C.2    Hutchinson, J.P.3    Hilder, E.F.4    Jacobson, G.A.5
  • 52
    • 77952888996 scopus 로고    scopus 로고
    • High-resolution preparative separation of glycosaminoglycan oligosaccharides by polyacrylamide gel electrophoresis
    • Laremore TN, Ly M, Solakyildirim K, Zagorevski DV, Linhardt RJ. 2010. High-resolution preparative separation of glycosaminoglycan oligosaccharides by polyacrylamide gel electrophoresis. Anal. Biochem. 401:236-41
    • (2010) Anal. Biochem. , vol.401 , pp. 236-41
    • Laremore, T.N.1    Ly, M.2    Solakyildirim, K.3    Zagorevski, D.V.4    Linhardt, R.J.5
  • 53
    • 0028855668 scopus 로고
    • Preparation and structural characterization of large heparin-derived oligosaccharides
    • Pervin A, Gallo C, Jandik KA, Han XJ, Linhardt RJ. 1995. Preparation and structural characterization of large heparin-derived oligosaccharides. Glycobiology 5:83-95
    • (1995) Glycobiology , vol.5 , pp. 83-95
    • Pervin, A.1    Gallo, C.2    Jandik, K.A.3    Han, X.J.4    Linhardt, R.J.5
  • 54
    • 0023654989 scopus 로고
    • Fractionation of heparin-derived oligosaccharides by gradient polyacrylamide-gel electrophoresis
    • Rice KG, Rottink MK, Linhardt RJ. 1987. Fractionation of heparin-derived oligosaccharides by gradient polyacrylamide-gel electrophoresis. Biochem. J. 244:515-22
    • (1987) Biochem. J. , vol.244 , pp. 515-22
    • Rice, K.G.1    Rottink, M.K.2    Linhardt, R.J.3
  • 55
    • 68849110486 scopus 로고    scopus 로고
    • Focusing of low-molecular-mass heparins in polycationic polyacrylamide matrices
    • Zilberstein G, Shlar I, Korol L, Baskin E, Fasoli E, et al. 2009. Focusing of low-molecular-mass heparins in polycationic polyacrylamide matrices. Anal. Chem. 81:6966-71
    • (2009) Anal. Chem. , vol.81 , pp. 6966-71
    • Zilberstein, G.1    Shlar, I.2    Korol, L.3    Baskin, E.4    Fasoli, E.5
  • 56
    • 0030033340 scopus 로고    scopus 로고
    • High-performance liquid chromatographic analysis of glycosaminoglycan- derived oligosaccharides
    • DOI 10.1016/0021-9673(95)00338-X
    • Imanari T, Toida T, Koshiishi I, Toyoda H. 1996. High-performance liquid chromatographic analysis of glycosaminoglycan-derived oligosaccharides. J. Chromatogr. A 720:275-93 (Pubitemid 26037622)
    • (1996) Journal of Chromatography A , vol.720 , Issue.1-2 , pp. 275-293
    • Imanari, T.1    Toida, T.2    Koshiishi, I.3    Toyoda, H.4
  • 57
    • 0022341862 scopus 로고
    • High-performance liquid chromatographic separation of heparin-derived oligosaccharides
    • DOI 10.1016/0003-2697(85)90518-4
    • Rice KG, Kim YS, Merchant ZM, Linhardt RJ. 1985. High-performance liquid chromatographic separation of heparin-derived oligosaccharides. Anal. Biochem. 150:325-31 (Pubitemid 16201194)
    • (1985) Analytical Biochemistry , vol.150 , Issue.2 , pp. 325-331
    • Rice, K.G.1    Kim, Y.S.2    Grant, A.C.3
  • 58
    • 72449142595 scopus 로고    scopus 로고
    • Characterization of heparin impurities with HPLC-NMR using weak anion exchange chromatography
    • Limtiaco JFK, Jones CJ, Larive CK. 2009. Characterization of heparin impurities with HPLC-NMR using weak anion exchange chromatography. Anal. Chem. 81:10116-23
    • (2009) Anal. Chem. , vol.81 , pp. 10116-23
    • Jfk, L.1    Jones, C.J.2    Larive, C.K.3
  • 59
    • 42049122573 scopus 로고    scopus 로고
    • Comparative glycomics of connective tissue glycosaminoglycans
    • DOI 10.1002/pmic.200700787
    • Hitchcock AM, Yates EA, Costello CE, Zaia J. 2008. Comparative glycomics of connective tissue glycosaminoglycans. Proteomics 8:1384-97 (Pubitemid 351518550)
    • (2008) Proteomics , vol.8 , Issue.7 , pp. 1384-1397
    • Hitchcock, A.M.1    Yates, K.E.2    Costello, C.E.3    Zaia, J.4
  • 60
    • 60549113534 scopus 로고    scopus 로고
    • A chip-based amide-HILIC LC/MS platform for glycosaminoglycan glycomics profiling
    • Staples GO, Bowman MJ, Costello CE, Hitchcock AM, Lau JM, et al. 2009. A chip-based amide-HILIC LC/MS platform for glycosaminoglycan glycomics profiling. Proteomics 9:686-95
    • (2009) Proteomics , vol.9 , pp. 686-95
    • Staples, G.O.1    Bowman, M.J.2    Costello, C.E.3    Hitchcock, A.M.4    Lau, J.M.5
  • 62
    • 49149086654 scopus 로고    scopus 로고
    • Ion pairing chromatography
    • Cecchi T. 2008. Ion pairing chromatography. Crit. Rev. Anal. Chem. 38:161-213
    • (2008) Crit. Rev. Anal. Chem. , vol.38 , pp. 161-213
    • Cecchi, T.1
  • 63
    • 85056970231 scopus 로고    scopus 로고
    • Lochmüller CH, Cecchi T, eds Boca Raton: Taylor & Francis
    • Lochmüller CH, Cecchi T, eds. 2009. Ion-Pair Chromatography and Related Techniques. Boca Raton: Taylor & Francis. 215 pp.
    • (2009) Ion-Pair Chromatography and Related Techniques
  • 64
    • 0035356912 scopus 로고    scopus 로고
    • Extended thermodynamic approach to ion interaction chromatography
    • DOI 10.1021/ac001341y
    • Cecchi T, Pucciarelli F, Passamonti P. 2001. Extended thermodynamic approach to ion interaction chromatography. Anal. Chem. 73:2632-39 (Pubitemid 32880668)
    • (2001) Analytical Chemistry , vol.73 , Issue.11 , pp. 2632-2639
    • Cecchi, T.1    Pucciarelli, F.2    Passamonti, P.3
  • 65
    • 0030899830 scopus 로고    scopus 로고
    • Ion-pair high-performance liquid chromatography for determining disaccharide composition in heparin and heparan sulphate
    • DOI 10.1016/S0021-9673(96)00930-2, PII S0021967396009302
    • Karamanos NK, Vanky P, Tzanakakis GN, Tsegenidis T, Hjerpe A. 1997. Ion-pair high-performance liquid chromatography for determining disaccharide composition in heparin and heparan sulphate. J. Chromatogr. A 765:169-79 (Pubitemid 27152227)
    • (1997) Journal of Chromatography A , vol.765 , Issue.2 , pp. 169-179
    • Karamanos, N.K.1    Vanky, P.2    Tzanakakis, G.N.3    Tsegenidis, T.4    Hjerpe, A.5
  • 66
    • 0142188760 scopus 로고    scopus 로고
    • Separation of a complex mixture of heparin-derived oligosaccharides using reversed-phase high-performance liquid chromatography
    • DOI 10.1016/S0021-9673(03)00779-9
    • Thanawiroon C, Linhardt RJ. 2003. Separation of a complex mixture of heparin-derived oligosaccharides using reversed-phase high-performance liquid chromatography. J. Chromatogr. A 1014:215-23 (Pubitemid 37311173)
    • (2003) Journal of Chromatography A , vol.1014 , Issue.1-2 , pp. 215-223
    • Thanawiroon, C.1    Linhardt, R.J.2
  • 67
    • 1642453684 scopus 로고    scopus 로고
    • Liquid chromatography/mass spectrometry sequencing approach for highly sulfated heparin-derived oligosaccharides
    • DOI 10.1074/jbc.M304772200
    • Thanawiroon C, Rice KG, Toida T, Linhardt RJ. 2004. Liquid chromatography/mass spectrometry sequencing approach for highly sulfated heparin-derived oligosaccharides. J. Biol. Chem. 279:2608-15 (Pubitemid 38114247)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.4 , pp. 2608-2615
    • Thanawiroon, C.1    Rice, K.G.2    Toida, T.3    Linhardt, R.J.4
  • 68
    • 0032898874 scopus 로고    scopus 로고
    • Rapid and sensitive analysis of disaccharide composition in heparin and heparan sulfate by reversed-phase ion-pair chromatography on a 2 μm porous silica gel column
    • DOI 10.1016/S0021-9673(98)00854-1, PII S0021967398008541
    • Toyoda H, Yamamoto H, Ogino N, Toida T, Imanari T. 1999. Rapid and sensitive analysis of disaccharide composition in heparin and heparan sulfate by reversed-phase ion-pair chromatography on a 2 μm porous silica gel column. J. Chromatogr. A 830:197-201 (Pubitemid 29034693)
    • (1999) Journal of Chromatography A , vol.830 , Issue.1 , pp. 197-201
    • Toyoda, H.1    Yamamoto, H.2    Ogino, N.3    Toida, T.4    Imanari, T.5
  • 70
    • 0034723308 scopus 로고    scopus 로고
    • Structural analysis of glycosaminoglycans in Drosophila and Caenorhabditis elegans and demonstration that tout-velu, a Drosophila gene related to EXT tumor suppressors, affects heparan sulfate in vivo
    • DOI 10.1074/jbc.275.4.2269
    • Toyoda H, Kinoshita-Toyoda A, Selleck SB. 2000. Structural analysis of glycosaminoglycans in Drosophila and Caenorhabditis elegans and demonstration that tout-velu, a Drosophila gene related to EXT tumor suppressors, affects heparan sulfate in vivo. J. Biol. Chem. 275:2269-75 (Pubitemid 30081981)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.4 , pp. 2269-2275
    • Toyoda, H.1    Kinoshita-Toyoda, A.2    Selleck, S.B.3
  • 71
    • 66149100934 scopus 로고    scopus 로고
    • Analysis of oligosaccharides derived from heparin by ion-pair reversed-phase chromatography/mass spectrometry
    • Doneanu CE, Chen W, Gebler JC. 2009. Analysis of oligosaccharides derived from heparin by ion-pair reversed-phase chromatography/mass spectrometry. Anal. Chem. 81:3485-99
    • (2009) Anal. Chem. , vol.81 , pp. 3485-99
    • Doneanu, C.E.1    Chen, W.2    Gebler, J.C.3
  • 72
    • 30744447270 scopus 로고    scopus 로고
    • Ion-pairing reversed-phased chromatography/mass spectrometry of heparin
    • DOI 10.1016/j.carres.2005.11.030, PII S0008621505005707
    • Henriksen J, Roepstorff P, Ringborg LH. 2006. Ion-pairing reversed-phased chromatography/mass spectrometry of heparin. Carbohydr. Res. 341:382-87 (Pubitemid 43098777)
    • (2006) Carbohydrate Research , vol.341 , Issue.3 , pp. 382-387
    • Henriksen, J.1    Roepstorff, P.2    Ringborg, L.H.3
  • 73
    • 0037167009 scopus 로고    scopus 로고
    • Analysis of heparan sulfate oligosaccharides with ion pair-reverse phase capillary high performance liquid chromatography-microelectrospray ionization time-of-flight mass spectrometry
    • DOI 10.1021/ja0178867
    • Kuberan B, Lech M, Zhang L, Wu ZL, Beeler DL, Rosenberg RD. 2002. Analysis of heparan sulfate oligosaccharides with ion pair-reverse phase capillary high performance liquid chromatography- microelectrospray ionization time-of-flight mass spectrometry. J. Am. Chem. Soc. 124:8707-18 (Pubitemid 34791042)
    • (2002) Journal of the American Chemical Society , vol.124 , Issue.29 , pp. 8707-8718
    • Kuberan, B.1    Lech, M.2    Zhang, L.3    Wu, Z.L.4    Beeler, D.L.5    Rosenberg, R.D.6
  • 74
    • 66349123838 scopus 로고    scopus 로고
    • Quantification of heparan sulfate disaccharides using ionpairing reversed-phasemicroflow high-performance liquid chromatography with electrospray ionization trap mass spectrometry
    • Zhang Z, Xie J, Liu H, Liu J, Linhardt RJ. 2009. Quantification of heparan sulfate disaccharides using ionpairing reversed-phasemicroflow high-performance liquid chromatography with electrospray ionization trap mass spectrometry. Anal. Chem. 81:4349-55
    • (2009) Anal. Chem. , vol.81 , pp. 4349-55
    • Zhang, Z.1    Xie, J.2    Liu, H.3    Liu, J.4    Linhardt, R.J.5
  • 75
    • 39449139029 scopus 로고    scopus 로고
    • Ultraperformance ion-pair liquid chromatography coupled to electrospray time-of-flight mass spectrometry for compositional profiling and quantification of heparin and heparan sulfate
    • DOI 10.1021/ac702235u
    • Korir AK, Limtiaco JFK, Gutierrez SM, Larive CK. 2008. Ultraperformance ion-pair liquid chromatography coupled to electrospray time-of-flight mass spectrometry for compositional profiling and quantification of heparin and heparan sulfate. Anal. Chem. 80:1297-306 (Pubitemid 351272368)
    • (2008) Analytical Chemistry , vol.80 , Issue.4 , pp. 1297-1306
    • Korir, A.K.1    Limtiaco, J.F.K.2    Gutierrez, S.M.3    Larive, C.K.4
  • 76
    • 72949098148 scopus 로고    scopus 로고
    • Insights into the mechanism of separation of heparin and heparan sulfate disaccharides by reversed-phase ion-pair chromatography
    • Jones CJ, Membreno N, Larive CK. 2010. Insights into the mechanism of separation of heparin and heparan sulfate disaccharides by reversed-phase ion-pair chromatography. J. Chromatogr. A 1217:479-88
    • (2010) J. Chromatogr. A , vol.1217 , pp. 479-88
    • Jones, C.J.1    Membreno, N.2    Larive, C.K.3
  • 77
    • 33646023284 scopus 로고    scopus 로고
    • Mass spectrometry for the analysis of highly charged sulfated carbohydrates
    • Chi LL, Amster J, Linhardt RJ. 2005. Mass spectrometry for the analysis of highly charged sulfated carbohydrates. Curr. Anal. Chem. 1:223-40
    • (2005) Curr. Anal. Chem. , vol.1 , pp. 223-40
    • Chi, L.L.1    Amster, J.2    Linhardt, R.J.3
  • 78
    • 0038290630 scopus 로고    scopus 로고
    • Tandem mass spectrometry of sulfated heparin-like glycosaminoglycan oligosaccharides
    • DOI 10.1021/ac0263418
    • Zaia J, Costello CE. 2003. Tandem mass spectrometry of sulfated heparin-like glycosaminoglycan oligosaccharides. Anal. Chem. 75:2445-55 (Pubitemid 36582831)
    • (2003) Analytical Chemistry , vol.75 , Issue.10 , pp. 2445-2455
    • Zaia, J.1    Costello, C.E.2
  • 80
    • 0029068089 scopus 로고
    • Utility of noncovalent complexes in the matrix-assisted laser-desorption ionization mass spectrometry of heparin-derived oligosaccharides
    • Juhasz P, Biemann K. 1995. Utility of noncovalent complexes in the matrix-assisted laser-desorption ionization mass spectrometry of heparin-derived oligosaccharides. Carbohydr. Res. 270:131-47
    • (1995) Carbohydr. Res. , vol.270 , pp. 131-47
    • Juhasz, P.1    Biemann, K.2
  • 81
    • 20444446991 scopus 로고    scopus 로고
    • Analysis of acidic carbohydrates as their quaternary ammonium or phosphonium salts by matrix-assisted laser desorption/ionization mass spectrometry
    • DOI 10.1016/j.carres.2005.04.013, PII S0008621505002077
    • Ueki M, Yamaguchi M. 2005. Analysis of acidic carbohydrates as their quaternary ammonium or phosphonium salts by matrix-assisted laser desorption/ionization mass spectrometry. Carbohydr. Res. 340:1722-31 (Pubitemid 40828480)
    • (2005) Carbohydrate Research , vol.340 , Issue.10 , pp. 1722-1731
    • Ueki, M.1    Yamaguchi, M.2
  • 82
    • 33947716025 scopus 로고    scopus 로고
    • Improved matrix-assisted laser desorption/ionization mass spectrometric detection of glycosaminoglycan disaccharides as cesium salts
    • DOI 10.1002/rcm.2964
    • Laremore TN, Linhardt RJ. 2007. Improved matrix-assisted laser desorption/ionization mass spectrometric detection of glycosaminoglycan disaccharides as cesium salts. Rapid Commun. Mass Spectrom. 21:1315-20 (Pubitemid 46506587)
    • (2007) Rapid Communications in Mass Spectrometry , vol.21 , Issue.7 , pp. 1315-1320
    • Laremore, T.N.1    Linhardt, R.J.2
  • 84
    • 73449129325 scopus 로고    scopus 로고
    • UV-MALDI-TOFmass spectrometry analysis of heparin oligosaccharides obtained by nitrous acid controlled degradation and high performance anion exchange chromatography
    • Bultel L, Landoni M, Grand E, Couto AS, Kovensky J. 2010. UV-MALDI-TOFmass spectrometry analysis of heparin oligosaccharides obtained by nitrous acid controlled degradation and high performance anion exchange chromatography. J. Am. Soc. Mass Spectrom. 21:178-90
    • (2010) J. Am. Soc. Mass Spectrom. , vol.21 , pp. 178-90
    • Bultel, L.1    Landoni, M.2    Grand, E.3    Couto, A.S.4    Kovensky, J.5
  • 85
    • 62149152738 scopus 로고    scopus 로고
    • Differentiation of 3-Osulfated heparin disaccharide isomers: Identification of structural aspects of the heparin CCL2 binding motif
    • Meissen JK, Sweeney MD, Girardi M, Lawrence R, Esko JD, Leary JA. 2009. Differentiation of 3-Osulfated heparin disaccharide isomers: identification of structural aspects of the heparin CCL2 binding motif. J. Am. Soc. Mass Spectrom. 20:652-57
    • (2009) J. Am. Soc. Mass Spectrom. , vol.20 , pp. 652-57
    • Meissen, J.K.1    Sweeney, M.D.2    Girardi, M.3    Lawrence, R.4    Esko, J.D.5    Leary, J.A.6
  • 86
    • 31044443979 scopus 로고    scopus 로고
    • Systematic identification of N-acetylheparosan oligosaccharides by tandem mass spectrometric fragmentation
    • DOI 10.1002/rcm.2310
    • Minamisawa T, Suzuki K, Hirabayashi J. 2006. Systematic identification of N-acetylheparosan oligosaccharides by tandem mass spectrometric fragmentation. Rapid Commun. Mass Spectrom. 20:267-74 (Pubitemid 43121630)
    • (2006) Rapid Communications in Mass Spectrometry , vol.20 , Issue.2 , pp. 267-274
    • Minamisawa, T.1    Suzuki, K.2    Hirabayashi, J.3
  • 87
    • 33847612428 scopus 로고    scopus 로고
    • Distinguishing glucuronic from iduronic acid in glycosaminoglycan tetrasaccharides by using electron detachment dissociation
    • DOI 10.1021/ac061636x
    • Wolff JJ, Chi LL, Linhardt RJ, Amster IJ. 2007. Distinguishing glucuronic from iduronic acid in glycosaminoglycan tetrasaccharides by using electron detachment dissociation. Anal. Chem. 79:2015-22 (Pubitemid 46355233)
    • (2007) Analytical Chemistry , vol.79 , Issue.5 , pp. 2015-2022
    • Wolff, J.J.1    Chi, L.2    Linhardt, R.J.3    Amster, I.J.4
  • 88
    • 0034603710 scopus 로고    scopus 로고
    • An NMR and molecular modeling study of the site-specific binding of histamine by heparin, chemically modified heparin, and heparin-derived oligosaccharides
    • DOI 10.1021/bi9926025
    • Chuang WL, Christ MD, Peng J, Rabenstein DL. 2000. An NMR and molecular modeling study of the site-specific binding of histamine by heparin, chemically modified heparin, and heparin-derived oligosaccharides. Biochemistry 39:3542-55 (Pubitemid 30183835)
    • (2000) Biochemistry , vol.39 , Issue.13 , pp. 3542-3555
    • Chuang, W.-L.1    Christ, M.D.2    Peng, J.3    Rabenstein, D.L.4
  • 89
    • 0035872350 scopus 로고    scopus 로고
    • 1H NMR experiments
    • DOI 10.1021/ac0100291
    • Chuang WL, Christ MD, Rabenstein DL. 2001. Determination of the primary structures of heparin- and heparan sulfate-derived oligosaccharides using band-selective homonuclear-decoupled two-dimensional H-1 NMR experiments. Anal. Chem. 73:2310-16 (Pubitemid 32880699)
    • (2001) Analytical Chemistry , vol.73 , Issue.10 , pp. 2310-2316
    • Chuang, W.-L.1    Christ, M.D.2    Rabenstein, D.L.3
  • 90
    • 70350604445 scopus 로고    scopus 로고
    • Broadening of H-1 NMR signals in the spectra of heparin and OSCS by paramagnetic transition metal ions. The use of EDTA to sharpen the signals
    • McEwen I. 2010. Broadening of H-1 NMR signals in the spectra of heparin and OSCS by paramagnetic transition metal ions. The use of EDTA to sharpen the signals. J. Pharm. Biomed. Anal. 51:733-35
    • (2010) J. Pharm. Biomed. Anal. , vol.51 , pp. 733-35
    • McEwen, I.1
  • 91
    • 8444233148 scopus 로고    scopus 로고
    • Chromatographic analysis and sequencing approach of heparin oligosaccharides using cetyltrimethylammonium dynamically coated stationary phases
    • DOI 10.1016/j.ab.2004.06.020, PII S0003269704005366
    • Mourier PAJ, Viskov C. 2004. Chromatographic analysis and sequencing approach of heparin oligosaccharides using cetyltrimethylammonium dynamically coated stationary phases. Anal. Biochem. 332:299- 313 (Pubitemid 39485739)
    • (2004) Analytical Biochemistry , vol.332 , Issue.2 , pp. 299-313
    • Mourier, P.A.J.1    Viskov, C.2
  • 92
    • 33847256557 scopus 로고    scopus 로고
    • Characterization of di- and monosulfated, unsaturated heparin disaccharides with terminal N-sulfated 1, 6-anhydro-β-Dglucosamine or N-sulfated 1, 6-anhydro-β-D-mannosamine residues
    • Mascellani G, Guerrini M, Torri G, Liverani L, Spelta F, Bianchini P. 2007. Characterization of di- and monosulfated, unsaturated heparin disaccharides with terminal N-sulfated 1, 6-anhydro-β-Dglucosamine or N-sulfated 1, 6-anhydro-β-D-mannosamine residues. Carbohydr. Res. 342:835-42
    • (2007) Carbohydr. Res. , vol.342 , pp. 835-42
    • Mascellani, G.1    Guerrini, M.2    Torri, G.3    Liverani, L.4    Spelta, F.5    Bianchini, P.6
  • 93
    • 0026451167 scopus 로고
    • One- and two-dimensional 1H-NMR characterization of two series of sulfated disaccharides prepared from chondroitin sulfate and heparan-sulfate heparin by bacterial eliminase digestion
    • Yamada S, Yoshida K, Sugiura M, Sugahara K. 1992. One- and two-dimensional 1H-NMR characterization of two series of sulfated disaccharides prepared from chondroitin sulfate and heparan-sulfate heparin by bacterial eliminase digestion. J. Biochem. 112:440-47
    • (1992) J. Biochem. , vol.112 , pp. 440-47
    • Yamada, S.1    Yoshida, K.2    Sugiura, M.3    Sugahara, K.4
  • 94
    • 0029658229 scopus 로고    scopus 로고
    • 1Hand13CNMRspectral assignments of the major sequences of twelve systematically modified heparin derivatives
    • Yates EA, Santini F, Guerrini M, Naggi A, Torri G, Casu B. 1996. 1Hand13CNMRspectral assignments of the major sequences of twelve systematically modified heparin derivatives. Carbohydr. Res. 294:15-27
    • (1996) Carbohydr. Res. , vol.294 , pp. 15-27
    • Yates, E.A.1    Santini, F.2    Guerrini, M.3    Naggi, A.4    Torri, G.5    Casu, B.6
  • 95
    • 0036435401 scopus 로고    scopus 로고
    • 13 C-labeled acetyl groups
    • DOI 10.1139/v02-132
    • Bendiak B, Fang TT, Jones DNM. 2002. An effective strategy for structural elucidation of oligosaccharides through NMRspectroscopy combined with peracetylation using doubly 13C-labeled acetyl groups. Can. J. Chem. 80:1032-50 (Pubitemid 35373399)
    • (2002) Canadian Journal of Chemistry , vol.80 , Issue.8 , pp. 1032-1050
    • Bendiak, B.1    Fang, T.T.2    Jones, D.N.M.3
  • 96
    • 0032718996 scopus 로고    scopus 로고
    • Novel multi-dimensional heteronuclear NMR techniques for the study of 13C-O-acetylated oligosaccharides: Expanding the dimensions for carbohydrate structures
    • Jones DNM, Bendiak B. 1999. Novel multi-dimensional heteronuclear NMR techniques for the study of 13C-O-acetylated oligosaccharides: expanding the dimensions for carbohydrate structures. J. Biomol. NMR 15:157-68
    • (1999) J. Biomol. NMR , vol.15 , pp. 157-68
    • Dnm, J.1    Bendiak, B.2
  • 97
    • 0032351694 scopus 로고    scopus 로고
    • Polymer additives mixture analysis using pulsed-field gradient NMR spectroscopy
    • Jayawickrama DA, Larive CK, McCord EF, Roe DC. 1998. Polymer additives mixture analysis using pulsed-field gradient NMR spectroscopy. Magn. Reson. Chem. 36:755-60
    • (1998) Magn. Reson. Chem. , vol.36 , pp. 755-60
    • Jayawickrama, D.A.1    Larive, C.K.2    McCord, E.F.3    Roe, D.C.4
  • 98
    • 0347359145 scopus 로고    scopus 로고
    • Diffusion ordered nuclear magnetic resonance spectroscopy: Principles and applications
    • PII S0079656599000035
    • Johnson CS Jr. 1999. Diffusion ordered nuclear magnetic resonance spectroscopy: principles and applications. Prog. Nucl. Magn. Reson. Spectrosc. 34:203-56 (Pubitemid 129595218)
    • (1999) Progress in Nuclear Magnetic Resonance Spectroscopy , vol.34 , Issue.3-4 , pp. 203-256
    • Johnson Jr., C.S.1
  • 99
    • 0001098519 scopus 로고
    • Diffusion-ordered two-dimensional nuclear magnetic resonance spectroscopy
    • Morris KF, Johnson CS. 1992. Diffusion-ordered two-dimensional nuclear magnetic resonance spectroscopy. J. Am. Chem. Soc. 114:3139-41
    • (1992) J. Am. Chem. Soc. , vol.114 , pp. 3139-41
    • Morris, K.F.1    Johnson, C.S.2
  • 100
    • 0028327522 scopus 로고
    • Analysis ofmixtures based onmolecular size and hydrophobicity by means of diffusion-ordered 2D NMR
    • Morris KF, Stilbs P, Johnson CS. 1994. Analysis ofmixtures based onmolecular size and hydrophobicity by means of diffusion-ordered 2D NMR. Anal. Chem. 66:211-15
    • (1994) Anal. Chem. , vol.66 , pp. 211-15
    • Morris, K.F.1    Stilbs, P.2    Johnson, C.S.3
  • 101
    • 58149093076 scopus 로고    scopus 로고
    • Assessment of oversulfated chondroitin sulfate in low molecular weight and unfractionated heparin diffusion ordered nuclear magnetic resonance spectroscopy method
    • Sitkowski J, Bednarek E, Bocian W, Kozerski L. 2008. Assessment of oversulfated chondroitin sulfate in low molecular weight and unfractionated heparin diffusion ordered nuclear magnetic resonance spectroscopy method. J. Med. Chem. 51:7663-65
    • (2008) J. Med. Chem. , vol.51 , pp. 7663-65
    • Sitkowski, J.1    Bednarek, E.2    Bocian, W.3    Kozerski, L.4
  • 102
    • 77954863340 scopus 로고    scopus 로고
    • An assessment of polydispersed species in unfractionated and low molecular weight heparins by diffusion ordered nuclear magnetic resonance spectroscopy method
    • Bednarek E, Sitkowski J, Bocian W, Mulloy B, Kozerski L. 2010. An assessment of polydispersed species in unfractionated and low molecular weight heparins by diffusion ordered nuclear magnetic resonance spectroscopy method. J. Pharm. Biomed. Anal. 53:302-8
    • (2010) J. Pharm. Biomed. Anal. , vol.53 , pp. 302-8
    • Bednarek, E.1    Sitkowski, J.2    Bocian, W.3    Mulloy, B.4    Kozerski, L.5
  • 105
    • 0037444518 scopus 로고    scopus 로고
    • Advancing NMR sensitivity for LC-NMR-MS using a cryoflow probe: Application to the analysis of acetaminophen metabolites in urine
    • DOI 10.1021/ac026203i
    • Spraul M, Freund AS, Nast RE, Withers RS, Maas WE, Corcoran O. 2003. Advancing NMR sensitivity for LC-NMR-MS using a cryoflow probe: application to the analysis of acetaminophen metabolites in urine. Anal. Chem. 75:1536-41 (Pubitemid 36397188)
    • (2003) Analytical Chemistry , vol.75 , Issue.6 , pp. 1536-1541
    • Spraul, M.1    Freund, A.S.2    Nast, R.E.3    Withers, R.S.4    Maas, W.E.5    Corcoran, O.6
  • 106
    • 33751021133 scopus 로고    scopus 로고
    • Extending the scope of NMR spectroscopy with microcoil probes
    • DOI 10.1002/anie.200601789
    • Schroeder FC, Gronquist M. 2006. Extending the scope of NMR spectroscopy with microcoil probes. Angew. Chem. Int. Ed. 45:7122-31 (Pubitemid 44748293)
    • (2006) Angewandte Chemie - International Edition , vol.45 , Issue.43 , pp. 7122-7131
    • Schroeder, F.C.1    Gronquist, M.2
  • 107
    • 34547431493 scopus 로고    scopus 로고
    • On-line NMR detection of microgram quantities of heparin-derived oligosaccharides and their structure elucidation by microcoil NMR
    • DOI 10.1007/s00216-007-1400-2
    • Korir AK, Larive CK. 2007. On-line NMR detection of microgram quantities of heparin-derived oligosaccharides and their structure elucidation by microcoil NMR. Anal. Bioanal. Chem. 388:1707-16 (Pubitemid 47173090)
    • (2007) Analytical and Bioanalytical Chemistry , vol.388 , Issue.8 , pp. 1707-1716
    • Korir, A.K.1    Larive, C.K.2
  • 108
    • 0038187624 scopus 로고    scopus 로고
    • Hyphenation of capillary separations with nuclear magnetic resonance spectroscopy
    • DOI 10.1016/S0021-9673(03)00447-3
    • Jayawickrama DA, Sweedler JV. 2003. Hyphenation of capillary separations with nuclear magnetic resonance spectroscopy. J. Chromatogr. A 1000:819-40 (Pubitemid 36638487)
    • (2003) Journal of Chromatography A , vol.1000 , Issue.1-2 , pp. 819-840
    • Jayawickrama, D.A.1    Sweedler, J.V.2
  • 110
    • 0000159085 scopus 로고    scopus 로고
    • High-Resolution NMR Spectroscopy of Sample Volumes from 1 nL to 10 μL
    • Lacey ME, Subramanian R, Olson DL, Webb AG, Sweedler JV. 1999. High-resolution NMR spectroscopy of sample volumes from 1 n L to 10 μL. Chem. Rev. 99:3133-52 (Pubitemid 129582907)
    • (1999) Chemical Reviews , vol.99 , Issue.10 , pp. 3133-3152
    • Lacey, M.E.1    Subramanian, R.2    Olson, D.L.3    Webb, A.G.4    Sweedler, J.V.5
  • 111
    • 0032587142 scopus 로고    scopus 로고
    • 1H NMR detection using periodic stopped-flow capillary electrophoresis
    • DOI 10.1021/ac990117+
    • Olson D, Lacey M, Webb A, Sweedler J. 1999. Nanoliter-volume 1H NMR detection using periodic stopped-flow capillary electrophoresis. Anal. Chem. 71:3070-76 (Pubitemid 29372720)
    • (1999) Analytical Chemistry , vol.71 , Issue.15 , pp. 3070-3076
    • Olson, D.L.1    Lacey, M.E.2    Webb, A.G.3    Sweedler, J.V.4
  • 112
  • 113
    • 24944591009 scopus 로고    scopus 로고
    • Separation and analysis of nanomole quantities of heparin oligosaccharides using on-line capillary isotachophoresis coupled with NMR detection
    • DOI 10.1021/ac050669u
    • Korir AK, Almeida VK, Malkin DS, Larive CK. 2005. Separation and analysis of nanomole quantities of heparin oligosaccharides using on-line capillary isotachophoresis coupled with NMR detection. Anal. Chem. 77:5998-6003 (Pubitemid 41324302)
    • (2005) Analytical Chemistry , vol.77 , Issue.18 , pp. 5998-6003
    • Korir, A.K.1    Almeida, V.K.2    Malkin, D.S.3    Larive, C.K.4
  • 114
    • 33750209984 scopus 로고    scopus 로고
    • Visualizing ion electromigration during isotachophoretic separations with capillary isotachophoresis-NMR
    • DOI 10.1021/ac061431o
    • Korir AK, Almeida VK, Larive CK. 2006. Visualizing ion electromigration during isotachophoretic separations with capillary isotachophoresis-NMR. Anal. Chem. 78:7078-87 (Pubitemid 44607548)
    • (2006) Analytical Chemistry , vol.78 , Issue.20 , pp. 7078-7087
    • Korir, A.K.1    Almeida, V.K.2    Larive, C.K.3
  • 115
    • 57849153892 scopus 로고    scopus 로고
    • Advances in the separation, sensitive detection, and characterization of heparin and heparan sulfate
    • DOI 10.1007/s00216-008-2412-2
    • Korir AK, Larive CK. 2009. Advances in the separation, sensitive detection, and characterization of heparin and heparan sulfate. Anal. Bioanal. Chem. 393:155-69 (Pubitemid 50295243)
    • (2009) Analytical and Bioanalytical Chemistry , vol.393 , Issue.1 , pp. 155-169
    • Korir, A.K.1    Larive, C.K.2
  • 116
    • 36448979956 scopus 로고    scopus 로고
    • Separation and analysis of trace degradants in a pharmaceutical formulation using on-line capillary isotachophoresis-NMR
    • DOI 10.1021/ac7016629
    • Eldridge SL, Almeida VK, Korir AK, Larive CK. 2007. Separation and analysis of trace degradants in a pharmaceutical formulation using on-line capillary isotachophoresis-NMR. Anal. Chem. 79:8446-53 (Pubitemid 350171351)
    • (2007) Analytical Chemistry , vol.79 , Issue.22 , pp. 8446-8453
    • Eldridge, S.L.1    Almeida, V.K.2    Korir, A.K.3    Larive, C.K.4
  • 117
    • 48149098245 scopus 로고    scopus 로고
    • Time-resolved dynamic nuclear polarization enhanced NMR spectroscopy
    • Bowen S, Hilty C. 2008. Time-resolved dynamic nuclear polarization enhanced NMR spectroscopy. Angew. Chem. Int. Ed. 47:5235-37
    • (2008) Angew. Chem. Int. Ed. , vol.47 , pp. 5235-37
    • Bowen, S.1    Hilty, C.2
  • 119
    • 0042868578 scopus 로고    scopus 로고
    • Principles and features of single-scan two-dimensional NMR spectroscopy
    • DOI 10.1021/ja030055b
    • Frydman L, Lupulescu A, Scherf T. 2003. Principles and features of single-scan two-dimensional NMR spectroscopy. J. Am. Chem. Soc. 125:9204-17 (Pubitemid 36903835)
    • (2003) Journal of the American Chemical Society , vol.125 , Issue.30 , pp. 9204-9217
    • Frydman, L.1    Lupulescu, A.2    Scherf, T.3
  • 120
    • 67649421621 scopus 로고    scopus 로고
    • Sequentially acquired two-dimensional NMR spectra from hyperpolarized sample
    • Zeng H, Bowen S, Hilty C. 2009. Sequentially acquired two-dimensional NMR spectra from hyperpolarized sample. J. Magn. Reson. 199:159-65
    • (2009) J. Magn. Reson. , vol.199 , pp. 159-65
    • Zeng, H.1    Bowen, S.2    Hilty, C.3
  • 121
    • 33748886858 scopus 로고    scopus 로고
    • B3LYP/6-311++G study of structure and spin-spin coupling constant in methyl 2-O-sulfo-α-l-iduronate
    • DOI 10.1016/j.carres.2006.07.010, PII S0008621506003600
    • Hricovíni M. 2006. B3LYP/6-3112+G study of structure and spin-spin coupling constant in methyl 2-O-sulfo-α-L-iduronate. Carbohydr. Res. 341:2575-80 (Pubitemid 44427780)
    • (2006) Carbohydrate Research , vol.341 , Issue.15 , pp. 2575-2580
    • Hricovini, M.1
  • 122
    • 44249097241 scopus 로고    scopus 로고
    • Depiction of the forces participating in the 2-O-sulfo-α-L-iduronic acid conformational preference in heparin sequences in aqueous solutions
    • Pol-Fachin L, Verli H. 2008. Depiction of the forces participating in the 2-O-sulfo-α-L-iduronic acid conformational preference in heparin sequences in aqueous solutions. Carbohydr. Res. 343:1435-45
    • (2008) Carbohydr. Res. , vol.343 , pp. 1435-45
    • Pol-Fachin, L.1    Verli, H.2
  • 123
    • 0030691889 scopus 로고    scopus 로고
    • NMR solution conformation of heparin-derived hexasaccharide
    • Mikhailov D, Linhardt RJ, Mayo KH. 1997. NMR solution conformation of heparin-derived hexasaccharide. Biochem. J. 328:51-61 (Pubitemid 27499439)
    • (1997) Biochemical Journal , vol.328 , Issue.1 , pp. 51-61
    • Mikhailov, D.1    Linhardt, R.J.2    Mayo, K.H.3
  • 126
    • 0033603869 scopus 로고    scopus 로고
    • Intensity-based measurement of homonuclear residual dipolar couplings from CT-COSY [9]
    • DOI 10.1021/ja9910558
    • Tian F, Bolon PJ, Prestegard JH. 1999. Intensity-based measurement of homonuclear residual dipolar couplings from CT-COSY. J. Am. Chem. Soc. 121:7712-13 (Pubitemid 29413740)
    • (1999) Journal of the American Chemical Society , vol.121 , Issue.33 , pp. 7712-7713
    • Tian, F.1    Bolon, P.J.2    Prestegard, J.H.3
  • 127
    • 70349994805 scopus 로고    scopus 로고
    • Residual dipolar coupling investigation of a heparin tetrasaccharide confirms the limited effect of flexibility of the iduronic acid on the molecular shape of heparin
    • Jin L, Hricovini M, Deakin JA, Lyon M, Uhrin D. 2009. Residual dipolar coupling investigation of a heparin tetrasaccharide confirms the limited effect of flexibility of the iduronic acid on the molecular shape of heparin. Glycobiology 19:1185-96
    • (2009) Glycobiology , vol.19 , pp. 1185-96
    • Jin, L.1    Hricovini, M.2    Deakin, J.A.3    Lyon, M.4    Uhrin, D.5
  • 128
    • 33748475886 scopus 로고    scopus 로고
    • 13C enrichment and NMR observation of acetyl groups
    • DOI 10.1529/biophysj.105.079913
    • Yu F, Prestegard JH. 2006. Structural monitoring of oligosaccharides through 13Cenrichment and NMR observation of acetyl groups. Biophys. J. 91:1952-59 (Pubitemid 44352456)
    • (2006) Biophysical Journal , vol.91 , Issue.5 , pp. 1952-1959
    • Yu, F.1    Prestegard, J.H.2


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