D-serine ameliorates neonatal polyI:C treatment-induced emotional and cognitive impairments in adult mice

Journal of Pharmacological Sciences

Volumn 120, Issue 3, 2012, Pages 213-227

  Nagai, Taku ^a   Yu, Jinghua ^a   Kitahara, Yuko ^a   Nabeshima, Toshitaka ^b   Yamada, Kiyofumi ^a,c  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b MEIJO UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Cognition; D amino acid oxidase; D serine; Emotion; PolyI:C

Indexed keywords

DEXTRO AMINO ACID OXIDASE; DEXTRO SERINE; DIZOCILPINE; MESSENGER RNA; POLYINOSINIC POLYCYTIDYLIC ACID; SERINE;

AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; DOSE RESPONSE; EMOTIONAL DISORDER; ENZYME ACTIVITY; HIPPOCAMPUS; MOUSE; NEWBORN; NONHUMAN; OPEN FIELD TEST; PREFRONTAL CORTEX; PREPULSE INHIBITION; RECOGNITION; SENSORY GATING; SOCIAL INTERACTION; STARTLE REFLEX;

EID: 84869408132     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.12142FP     Document Type: Article

References (64)

1. Atladóttir HO, Thorsen P, Østergaard L, Schendel DE, Lemcke S, Abdallah M, et al. Maternal infection requiring hospitalization during pregnancy and autism spectrum disorders. J Autism Dev Disord. 2010;40:1423-1430.
2. Brown AS, Derkits EJ. Prenatal infection and schizophrenia: a review of epidemiologic and translational studies. Am J Psychiatry. 2010;167:261-280.
3. Leask SJ, Done DJ, Crow TJ. Adult psychosis, common childhood infections and neurological soft signs in a national birth cohort. Br J Psychiatry. 2002;181:387-392. (Pubitemid 35333105)
4. Gattaz WF, Abrahão AL, Foccacia R. Childhood meningitis, brain maturation and the risk of psychosis. Eur Arch Psychiatry Clin Neurosci. 2004;254:23-26. (Pubitemid 39310545)
5. Koponen H, Rantakallio P, Veijola J, Jones P, Jokelainen J, Isohanni M. Childhood central nervous system infections and risk for schizophrenia. Eur Arch Psychiatry Clin Neurosci. 2004;254:9-13. (Pubitemid 39310543)
6. Brown AS. The risk for schizophrenia from childhood and adult infections. Am J Psychiatry. 2008;165:7-10. (Pubitemid 351704543)
7. Meyer U, Feldon J. Epidemiology-driven neurodevelopmental animal models of schizophrenia. Prog Neurobiol. 2010;90:285-326.
8. Patterson PH. Maternal infection and immune involvement in autism. Trends Mol Med. 2011;17:389-394.
9. Wang T, Town T, Alexopoulou L, Anderson JF, Fikrig E, Flavell RA. Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis. Nat Med. 2004;10:1366-1373. (Pubitemid 40022719)
10. Shi L, Fatemi SH, Sidwell RW, Patterson PH. Maternal influenza infection causes marked behavioral and pharmacological changes in the offspring. J Neurosci. 2003;23:297-302. (Pubitemid 36050430)
11. Meyer U, Feldon J, Schedlowski M, Yee BK. Towards an immuno-precipitated neurodevelopmental animal model of schizophrenia. Neurosci Biobehav Rev. 2005;29:913-947. (Pubitemid 41097394)
12. Meyer U, Nyffeler M, Engler A, Urwyler A, Schedlowski M, Knuesel I, et al. The time of prenatal immune challenge determines the specificity of inflammation-mediated brain and behavioral pathology. J Neurosci. 2006;26:4752-4762. (Pubitemid 44315314)
13. Patterson PH. Maternal effects on schizophrenia risk. Science. 2007;318:576-577. (Pubitemid 350017607)
14. Ibi D, Nagai T, Kitahara Y, Mizoguchi H, Koike H, Shiraki A, et al. Neonatal polyI:C treatment in mice results in schizophrenia-like behavioral and neurochemical abnormalities in adulthood. Neurosci Res. 2009;64:297-305.
15. Yu J, Nagai T, Ibi D, Kitahara Y, Nabeshima T, Yamada K. Nicotine ameliorates emotional and cognitive impairments induced by neonatal polyI:C treatment in mice. Open Behav Sci J. 2010;4:9-18.
16. Clancy B, Darlington RB, Finlay BL. Translating developmental time across mammalian species. Neuroscience. 2001;105:7-17. (Pubitemid 32722089)
17. Virgintino D, Maiorano E, Errede M, Vimercati A, Greco P, Selvaggi L, et al. Astroglia-microvessel relationship in the developing human telencephalon. Int J Dev Biol. 1998;42:1165-1168. (Pubitemid 28561899)
18. Hashimoto A, Oka T, Nishikawa T. Anatomical distribution and postnatal changes in endogenous free D-aspartate and D-serine in rat brain and periphery. Eur J Neurosci. 1995;7:1657-1663.
19. Hashimoto K, Fukushima T, Shimizu E, Komatsu N, Watanabe H, Shinoda N, et al. Decreased serum levels of D-serine in patients with schizophrenia: evidence in support of the N-methyl-D-aspartate receptor hypofunction hypothesis of schizophrenia. Arch Gen Psychiatry. 2003;60:572-576. (Pubitemid 36682314)
20. Hashimoto K, Engberg G, Shimizu E, Nordin C, Lindström LH, Iyo M. Reduced D-serine to total serine ratio in the cerebrospinal fluid of drug naive schizophrenic patients. Prog Neuropsychopharmacol Biol Psychiatry. 2005;29:767-769. (Pubitemid 40897791)
21. Yamada K, Ohnishi T, Hashimoto K, Ohba H, Iwayama-Shigeno Y, Toyoshima M, et al. Identification of multiple serine racemase (SRR) mRNA isoforms and genetic analyses of SRR and DAO in schizophrenia and D-serine levels. Biol Psychiatry. 2005;57:1493-1503. (Pubitemid 40805378)
22. Bendikov I, Nadri C, Amar S, Panizzutti R, De Miranda J, Wolosker H, et al. A CSF and postmortem brain study of D-serine metabolic parameters in schizophrenia. Schizophr Res. 2007;9:41-51. (Pubitemid 46177566)
23. Tsai G, Yang P, Chung LC, Lange N, Coyle JT. D-serine added to antipsychotics for the treatment of schizophrenia. Biol Psychiatry. 1998;44:1081-1089. (Pubitemid 28547143)
24. Lane HY, Liu YC, Huang CL, Chang YC, Liau CH, Perng CH, et al. Sarcosine (N-methylglycine) treatment for acute schizophrenia: a randomized, double-blind study. Biol Psychiatry. 2008;63:9-12. (Pubitemid 350234891)
25. Kantrowitz JT, Malhotra AK, Cornblatt B, Silipo G, Balla A, Suckow RF, et al. High dose D-serine in the treatment of schizophrenia. Schizophr Res. 2010;121:125-130.
26. Nishikawa T. Analysis of free D-serine in mammals and its biological relevance. J Chromatogr B Analyt Technol Biomed Life Sci. 2011;879:3169-3183.
27. Fadda E, Danysz W, Wroblewski JT, Costa E. Glycine and D-serine increase the affinity of N-methyl-D-aspartate sensitive glutamate binding sites in rat brain synaptic membranes. Neuropharmacology. 1988;27:1183-1185. (Pubitemid 18261183)
28. Hashimoto K, Fujita Y, Horio M, Kunitachi S, Iyo M, Ferraris D, et al. Co-administration of a D-amino acid oxidase inhibitor potentiates the efficacy of D-serine in attenuating prepulse inhibition deficits after administration of dizocilpine. Biol Psychiatry. 2009;65:1103-1106.
29. Vezzani A, Serafini R, Stasi MA, Caccia S, Conti I, Tridico RV, et al. Kinetics of MK-801 and its effect on quinolinic acid-induced seizures and neurotoxicity in rats. J Pharmacol Exp Ther. 1989; 249:278-283. (Pubitemid 19115820)
30. Ferraris D, Duvall B, Ko YS, Thomas AG, Rojas C, Majer P, et al. Synthesis and biological evaluation of D-amino acid oxidase inhibitors. J Med Chem. 2008;51:3357-3359. (Pubitemid 351874993)
31. Takahashi K, Nagai T, Kamei H, Maeda K, Matsuya T, Arai S, et al. Neural circuits containing pallidotegmental GABAergic neurons are involved in the prepulse inhibition of the startle reflex in mice. Biol Psychiatry. 2007;62:148-157. (Pubitemid 46963245)
32. Lee PR, Brady DL, Shapiro RA, Dorsa DM, Koenig JI. Social interaction deficits caused by chronic phencyclidine administration are reversed by oxytocin. Neuropsychopharmacology. 2005;30:1883-1894. (Pubitemid 41486413)
33. Nagai T, Takuma K, Kamei H, Ito Y, Nakamichi N, Ibi D, et al. Dopamine D1 receptors regulate protein synthesis-dependent long-term recognition memory via extracellular signal-regulated kinase 1/2 in the prefrontal cortex. Learn Mem. 2007;14:117-125. (Pubitemid 46495188)
34. Tremolizzo L, Doueiri MS, Dong E, Grayson DR, Davis J, Pinna G, et al. Valproate corrects the schizophrenia-like epigenetic behavioral modifications induced by methionine in mice. Biol Psychiatry. 2005;57:500-509. (Pubitemid 40311985)
35. Ibi D, Takuma K, Koike H, Mizoguchi H, Tsuritani K, Kuwahara Y, et al. Social isolation rearing-induced impairment of the hippocampal neurogenesis is associated with deficits in spatial memory and emotion-related behaviors in juvenile mice. J Neurochem. 2008;105:921-932. (Pubitemid 351562741)
36. Watanabe T, Motomura Y, Suga T. A new colorimetric determination of D-amino acid oxidase and urate oxidase activity. Anal Biochem. 1978;86:310-315. (Pubitemid 9050400)
37. Konno R, Yasumura Y. Mouse mutant deficient in D-amino acid oxidase activity. Genetics. 1983;103:277-285. (Pubitemid 13147202)
38. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951; 193:265-275.
39. Lisman JE, Coyle JT, Green RW, Javitt DC, Benes FM, Heckers S, et al. Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia. Trends Neurosci. 2008;31:234-242.
40. Luby ED, Cohen BD, Rosenbaum G, Gottlieb JS, Kelley R. Study of a new schizophrenomimetic drug; sernyl. AMA Arch Neurol Psychiatry. 1959;81:363-369.
41. Lahti AC, Holcomb HH, Medoff DR, Tamminga CA. Ketamine activates psychosis and alters limbic blood flow in schizophrenia. Neuroreport. 1995;6:869-872.
42. Malhotra AK, Pinals DA, Adler CM, Elman I, Clifton A, Pickar D, et al. Ketamine-induced exacerbation of psychotic symptoms and cognitive impairment in neuroleptic-free schizophrenics. Neuropsychopharmacology. 1997;17:141-150. (Pubitemid 27365955)
43. Javitt DC, Zukin SR. Recent advances in the phencyclidine model of schizophrenia. Am J Psychiatry. 1991;148:1301-1308.
44. Krystal JH, Karper LP, Seibyl JP, Freeman GK, Delaney R, Bremner JD, et al. Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses. Arch Gen Psychiatry. 1994;51:199-214. (Pubitemid 24081509)
45. Krystal JH, Bennett A, Abi-Saab D, Belger A, Karper LP, D'Souza DC, et al. Dissociation of ketamine effects on rule acquisition and rule implementation: possible relevance to NMDA receptor contributions to executive cognitive functions. Biol Psychiatry. 2000;47:137-143. (Pubitemid 30069737)
46. Gilmour G, Dix S, Fellini L, Gastambide F, Plath N, Steckler T, et al. NMDA receptors, cognition and schizophrenia - Testing the validity of the NMDA receptor hypofunction hypothesis. Neuropharmacology. 2012;62:1401-1412.
47. Bayer SA, Altman J, Russo RJ, Zhang X. Timetables of neurogenesis in the human brain based on experimentally determined patterns in the rat. Neurotoxicology. 1993;14:83-144. (Pubitemid 23195769)
48. Lipina T, Labrie V, Weiner I, Roder J. Modulators of the glycine site on NMDA receptors, D-serine and ALX 5407, display similar beneficial effects to clozapine in mouse models of schizophrenia. Psychopharmacology. 2005;179:54-67. (Pubitemid 40576692)
49. Vuillermot S, Weber L, Feldon J, Meyer U. A longitudinal examination of the neurodevelopmental impact of prenatal immune activation in mice reveals primary defects in dopaminergic development relevant to schizophrenia. J Neurosci. 2010;30:1270-1287.
50. Winter C, Djodari-Irani A, Sohr R, Morgenstern R, Feldon J, Juckel G, et al. Prenatal immune activation leads to multiple changes in basal neurotransmitter levels in the adult brain: implications for brain disorders of neurodevelopmental origin such as schizophrenia. Int J Neuropsychopharmacol. 2009;12:513-524.
51. Kakegawa W, Miyoshi Y, Hamase K, Matsuda S, Matsuda K, Kohda K, et al. D-serine regulates cerebellar LTD and motor coordination through the δ2 glutamate receptor. Nat Neurosci. 2011;14:603-611.
52. Xia M, Liu Y, Figueroa DJ, Chiu CS, Wei N, Lawlor AM, et al. Characterization and localization of a human serine racemase. Brain Res Mol Brain Res. 2004;125:96-104. (Pubitemid 38757395)
53. Moreno S, Nardacci R, Cimini A, Cerù MP. Immunocytochemical localization of D-amino acid oxidase in rat brain. J Neurocytol. 1999;28:169-185. (Pubitemid 30123547)
54. Wang LZ, Zhu XZ. Spatiotemporal relationships among D-serine, serine racemase, and D-amino acid oxidase during mouse post-natal development. Acta Pharmacol Sin. 2003;24:965-974.
55. Chumakov I, Blumenfeld M, Guerassimenko O, Cavarec L, Palicio M, Abderrahim H, et al. Genetic and physiological data implicating the new human gene G72 and the gene for d-amino acid oxidase in schizophrenia. Proc Natl Acad Sci U S A. 2002;99:13675-13680. (Pubitemid 35215440)
56. Schumacher J, Jamra RA, Freudenberg J, Becker T, Ohlraun S, Otte AC, et al. Examination of G72 and d-amino-acid oxidase as genetic risk factors for schizophrenia and bipolar affective disorder. Mol Psychiatry. 2004;9:203-207. (Pubitemid 38299535)
57. Goltsov AY, Loseva JG, Andreeva TV, Grigorenko AP, Abramova LI, Kaleda VG, et al. Polymorphism in the 5'-promoter region of serine racemase gene in schizophrenia. Mol Psychiatry. 2006;11:325-326.
58. Morita Y, Ujike H, Tanaka Y, Otani K, Kishimoto M, Morio A, et al. A genetic variant of the serine racemase gene is associated with schizophrenia. Biol Psychiatry. 2007;61:1200-1203. (Pubitemid 46669458)
59. Detera-Wadleigh SD, McMahon FJ. G72/G30 in schizophrenia and bipolar disorder: review and meta-analysis. Biol Psychiatry. 2006;60:106-114. (Pubitemid 44026593)
60. Basu AC, Tsai GE, Ma CL, Ehmsen JT, Mustafa AK, Han L, et al. Targeted disruption of serine racemase affects glutamatergic neurotransmission and behavior. Mol Psychiatry. 2009;14:719-727.
61. DeVito LM, Balu DT, Kanter BR, Lykken C, Basu AC, Coyle JT, et al. Serine racemase deletion disrupts memory for order and alters cortical dendritic morphology. Genes Brain Behav. 2011;10:210-222.
62. Labrie V, Fukumura R, Rastogi A, Fick LJ, Wang W, Boutros PC, et al. Serine racemase is associated with schizophrenia susceptibility in humans and in a mouse model. Hum Mol Genet. 2009;18:3227-3243.
63. Labrie V, Duffy S, Wang W, Barger SW, Baker GB, Roder JC. Genetic inactivation of D-amino acid oxidase enhances extinction and reversal learning in mice. Learn Mem. 2009;16:28-37.
64. Labrie V, Wang W, Barger SW, Baker GB, Roder JC. Genetic loss of D-amino acid oxidase activity reverses schizophrenia-like phenotypes in mice. Genes Brain Behav. 2010;9:11-25.