메뉴 건너뛰기




Volumn 7, Issue 5, 2012, Pages 493-495

Bcl10 and methylation of fatty acids: A future therapeutic target for Type 2 diabetes?

Author keywords

fatty acids; inflammation; insulin resistance; NAFLD; obesity; Type 2 diabetes

Indexed keywords

CHYLOMICRON; DIACYLGLYCEROL; FAT DROPLET; FATTY ACID; INSULIN RECEPTOR KINASE; INTERLEUKIN 6; LIPID; PROTEIN BCL 10; PROTEIN KINASE C EPSILON; SALSALATE; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; VERY LOW DENSITY LIPOPROTEIN;

EID: 84869382804     PISSN: 17584299     EISSN: 17584302     Source Type: Journal    
DOI: 10.2217/clp.12.56     Document Type: Review
Times cited : (1)

References (21)
  • 1
    • 84860497397 scopus 로고    scopus 로고
    • Diacylglycerol activation of protein kinase Cepsilon and hepatic insulin resistance
    • Jornayvaz FR, Shulman GI. Diacylglycerol activation of protein kinase Cepsilon and hepatic insulin resistance. Cell Metab. 15(5), 574-584 (2012).
    • (2012) Cell Metab. , vol.15 , Issue.5 , pp. 574-584
    • Jornayvaz, F.R.1    Shulman, G.I.2
  • 2
    • 75449094816 scopus 로고    scopus 로고
    • Obesity and nonalcoholic fatty liver disease: Biochemical, metabolic, and clinical implications
    • Fabbrini E, Sullivan S, Klein S. Obesity and nonalcoholic fatty liver disease: Biochemical, metabolic, and clinical implications. Hepatology 51(2), 679-689 (2010).
    • (2010) Hepatology , vol.51 , Issue.2 , pp. 679-689
    • Fabbrini, E.1    Sullivan, S.2    Klein, S.3
  • 4
    • 79954996869 scopus 로고    scopus 로고
    • Hepatic insulin resistance in mice with hepatic overexpression of diacylglycerol acyltransferase 2
    • Jornayvaz FR, Birkenfeld AL, Jurczak MJ et al. Hepatic insulin resistance in mice with hepatic overexpression of diacylglycerol acyltransferase 2. Proc. Natl Acad. Sci. USA 108(14), 5748-5752 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , Issue.14 , pp. 5748-5752
    • Jornayvaz, F.R.1    Birkenfeld, A.L.2    Jurczak, M.J.3
  • 5
    • 78349242167 scopus 로고    scopus 로고
    • A high-fat, ketogenic diet causes hepatic insulin resistance in mice, despite increasing energy expenditure and preventing weight gain
    • Jornayvaz FR, Jurczak MJ, Lee HY et al. A high-fat, ketogenic diet causes hepatic insulin resistance in mice, despite increasing energy expenditure and preventing weight gain. Am. J. Physiol. Endocrinol. Metab. 299(5), e808-e815 (2010).
    • (2010) Am. J. Physiol. Endocrinol. Metab. , vol.299 , Issue.5
    • Jornayvaz, F.R.1    Jurczak, M.J.2    Lee, H.Y.3
  • 6
    • 84862907611 scopus 로고    scopus 로고
    • Thyroid hormone receptor-alpha gene knockout mice are protected from dietinduced hepatic insulin resistance
    • Jornayvaz FR, Lee HY, Jurczak MJ et al. Thyroid hormone receptor-alpha gene knockout mice are protected from dietinduced hepatic insulin resistance. Endocrinology 153(2), 583-591 (2012).
    • (2012) Endocrinology , vol.153 , Issue.2 , pp. 583-591
    • Jornayvaz, F.R.1    Lee, H.Y.2    Jurczak, M.J.3
  • 7
    • 80055057797 scopus 로고    scopus 로고
    • Apolipoprotein CIII overexpressing mice are predisposed to diet-induced hepatic steatosis and hepatic insulin resistance
    • Lee HY, Birkenfeld AL, Jornayvaz FR et al. Apolipoprotein CIII overexpressing mice are predisposed to diet-induced hepatic steatosis and hepatic insulin resistance. Hepatology 54(5), 1650-1660 (2011).
    • (2011) Hepatology , vol.54 , Issue.5 , pp. 1650-1660
    • Lee, H.Y.1    Birkenfeld, A.L.2    Jornayvaz, F.R.3
  • 8
    • 80053627289 scopus 로고    scopus 로고
    • Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease
    • Kumashiro N, Erion DM, Zhang D et al. Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease. Proc. Natl Acad. Sci. USA 108(39), 16381-16385 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , Issue.39 , pp. 16381-16385
    • Kumashiro, N.1    Erion, D.M.2    Zhang, D.3
  • 9
    • 79951697487 scopus 로고    scopus 로고
    • Liver ATP synthesis is lower and relates to insulin sensitivity in patients with Type 2 diabetes
    • Schmid AI, Szendroedi J, Chmelik M, Krssak M, Moser E, Roden M. Liver ATP synthesis is lower and relates to insulin sensitivity in patients with Type 2 diabetes. Diabetes Care 34(2), 448-453 (2011).
    • (2011) Diabetes Care , vol.34 , Issue.2 , pp. 448-453
    • Schmid, A.I.1    Szendroedi, J.2    Chmelik, M.3    Krssak, M.4    Moser, E.5    Roden, M.6
  • 10
    • 82955239838 scopus 로고    scopus 로고
    • Excessive hepatic mitochondrial TCA cycle and gluconeogenesis in humans with nonalcoholic fatty liver disease
    • Sunny NE, Parks EJ, Browning JD, Burgess SC. Excessive hepatic mitochondrial TCA cycle and gluconeogenesis in humans with nonalcoholic fatty liver disease. Cell Metab. 14(6), 804-810 (2011).
    • (2011) Cell Metab. , vol.14 , Issue.6 , pp. 804-810
    • Sunny, N.E.1    Parks, E.J.2    Browning, J.D.3    Burgess, S.C.4
  • 12
    • 80051971972 scopus 로고    scopus 로고
    • Reversal of muscle insulin resistance with exercise reduces postprandial hepatic de novo lipogenesis in insulin resistant individuals
    • Rabol R, Petersen KF, Dufour S, Flannery C, Shulman GI. Reversal of muscle insulin resistance with exercise reduces postprandial hepatic de novo lipogenesis in insulin resistant individuals. Proc. Natl Acad. Sci. USA 108(33), 13705-13709 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , Issue.33 , pp. 13705-13709
    • Rabol, R.1    Petersen, K.F.2    Dufour, S.3    Flannery, C.4    Shulman, G.I.5
  • 14
    • 78650878363 scopus 로고    scopus 로고
    • NF-kB, inflammation, and metabolic disease
    • Baker RG, Hayden MS, Ghosh S. NF-kB, inflammation, and metabolic disease. Cell Metab. 13(1), 11-22 (2011).
    • (2011) Cell Metab. , vol.13 , Issue.1 , pp. 11-22
    • Baker, R.G.1    Hayden, M.S.2    Ghosh, S.3
  • 15
    • 0035907302 scopus 로고    scopus 로고
    • Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4
    • Lee JY, Sohn KH, Rhee SH, Hwang D. Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4. J. Biol. Chem. 276(20), 16683-16689 (2001).
    • (2001) J. Biol. Chem. , vol.276 , Issue.20 , pp. 16683-16689
    • Lee, J.Y.1    Sohn, K.H.2    Rhee, S.H.3    Hwang, D.4
  • 17
    • 34250681374 scopus 로고    scopus 로고
    • CARD-Bcl10-Malt1 signalosomes: Missing link to NF-kappaB
    • Wegener E, Krappmann D. CARD-Bcl10-Malt1 signalosomes: Missing link to NF-kappaB. Sci. STKE 384, pe21 (2007).
    • (2007) Sci. STKE , vol.384 , pp. 21
    • Wegener, E.1    Krappmann, D.2
  • 18
    • 84861692219 scopus 로고    scopus 로고
    • Bcl10 links saturated fat overnutrition with hepatocellular NF-kappaB activation and insulin resistance
    • van Beek M, Oravecz-Wilson KI, Delekta PC et al. Bcl10 links saturated fat overnutrition with hepatocellular NF-kappaB activation and insulin resistance. Cell Rep. 1(5), 444-452 (2012).
    • (2012) Cell Rep. , vol.1 , Issue.5 , pp. 444-452
    • Van Beek, M.1    Oravecz-Wilson, K.I.2    Delekta, P.C.3
  • 19
    • 14644435731 scopus 로고    scopus 로고
    • Reversal of nonalcoholic hepatic steatosis, hepatic insulin resistance, and hyperglycemia by moderate weight reduction in patients with type 2 diabetes
    • DOI 10.2337/diabetes.54.3.603
    • Petersen KF, Dufour S, Befroy D, Lehrke M, Hendler RE, Shulman GI. Reversal of nonalcoholic hepatic steatosis, hepatic insulin resistance, and hyperglycemia by moderate weight reduction in patients with Type 2 diabetes. Diabetes 54(3), 603-608 (2005). (Pubitemid 40322060)
    • (2005) Diabetes , vol.54 , Issue.3 , pp. 603-608
    • Petersen, K.F.1    Dufour, S.2    Befroy, D.3    Lehrke, M.4    Hendler, R.E.5    Shulman, G.I.6
  • 20
    • 0029906375 scopus 로고    scopus 로고
    • Effects of an engineered human anti-TNF-α antibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM
    • Ofei F, Hurel S, Newkirk J, Sopwith M, Taylor R. Effects of an engineered human anti-TNF-alpha antibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM. Diabetes 45(7), 881-885 (1996). (Pubitemid 26225502)
    • (1996) Diabetes , vol.45 , Issue.3 SUPPL. , pp. 881-885
    • Ofei, F.1    Hurel, S.2    Newkirk, J.3    Sopwith, M.4    Taylor, R.5
  • 21
    • 77950885686 scopus 로고    scopus 로고
    • The effects of salsalate on glycemic control in patients with Type 2 diabetes: A randomized trial
    • Goldfine AB, Fonseca V, Jablonski KA, Pyle L, Staten MA, Shoelson SE. The effects of salsalate on glycemic control in patients with Type 2 diabetes: A randomized trial. Ann. Intern. Med. 152(6), 346-357 (2010).
    • (2010) Ann. Intern. Med. , vol.152 , Issue.6 , pp. 346-357
    • Goldfine, A.B.1    Fonseca, V.2    Jablonski, K.A.3    Pyle, L.4    Staten, M.A.5    Shoelson, S.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.