-
1
-
-
36749001029
-
The way forward in HCV treatment-finding the right path
-
Manns M.P., Foster G.R., Rockstroh J.K., Zeuzem S., Zoulim F., Houghton M. (2007) The way forward in HCV treatment-finding the right path. Nat Rev Drug Discov 6: 991-1000.
-
(2007)
Nat Rev Drug Discov
, vol.6
, pp. 991-1000
-
-
Manns, M.P.1
Foster, G.R.2
Rockstroh, J.K.3
Zeuzem, S.4
Zoulim, F.5
Houghton, M.6
-
2
-
-
67349222208
-
Metabolic factors and subsequent risk of hepatocellular carcinoma by hepatitis virus infection status: a large-scale population-based cohort study of Japanese men and women (JPHC Study Cohort II)
-
Inoue M., Kurahashi N., Iwasaki M., Tanaka Y., Mizokami M., Noda M., Tsugane S. (2009) Metabolic factors and subsequent risk of hepatocellular carcinoma by hepatitis virus infection status: a large-scale population-based cohort study of Japanese men and women (JPHC Study Cohort II). Cancer Causes Control 20: 741-50.
-
(2009)
Cancer Causes Control
, vol.20
, pp. 741-750
-
-
Inoue, M.1
Kurahashi, N.2
Iwasaki, M.3
Tanaka, Y.4
Mizokami, M.5
Noda, M.6
Tsugane, S.7
-
3
-
-
0043037223
-
High body mass index is an independent risk factor for nonresponse to antiviral treatment in chronic hepatitis C
-
Bressler B.L., Guindi M., Tomlinson G., Heathcote J. (2003) High body mass index is an independent risk factor for nonresponse to antiviral treatment in chronic hepatitis C. Hepatology 38: 639-44.
-
(2003)
Hepatology
, vol.38
, pp. 639-644
-
-
Bressler, B.L.1
Guindi, M.2
Tomlinson, G.3
Heathcote, J.4
-
4
-
-
15744381704
-
Insulin resistance impairs sustained response rate to peginterferon plus ribavirin in chronic hepatitis C patients
-
Romero-Gomez M., Del Mar Viloria M., Andrade R.J., Salmeron J., Diago M., Fernandez-Rodriguez C.M., Corpas R., Cruz M., Grande L., Vazquez L., Munoz-De-Rueda P., Lopez-Serrano P., Gila A., Gutierrez M.L., Perez C., Ruiz-Extremera A., Suarez E., Castillo J. (2005) Insulin resistance impairs sustained response rate to peginterferon plus ribavirin in chronic hepatitis C patients. Gastroenterology 128: 636-41.
-
(2005)
Gastroenterology
, vol.128
, pp. 636-641
-
-
Romero-Gomez, M.1
Del Mar Viloria, M.2
Andrade, R.J.3
Salmeron, J.4
Diago, M.5
Fernandez-Rodriguez, C.M.6
Corpas, R.7
Cruz, M.8
Grande, L.9
Vazquez, L.10
Munoz-De-Rueda, P.11
Lopez-Serrano, P.12
Gila, A.13
Gutierrez, M.L.14
Perez, C.15
Ruiz-Extremera, A.16
Suarez, E.17
Castillo, J.18
-
5
-
-
0024786438
-
Purification and characterization of the AMP-activated protein kinase. Copurification of acetyl-CoA carboxylase kinase and 3-hydroxy-3-methylglutaryl-CoA reductase kinase activities
-
Carling D., Clarke P.R., Zammit V.A., Hardie D.G. (1989) Purification and characterization of the AMP-activated protein kinase. Copurification of acetyl-CoA carboxylase kinase and 3-hydroxy-3-methylglutaryl-CoA reductase kinase activities. Eur J Biochem 186: 129-36.
-
(1989)
Eur J Biochem
, vol.186
, pp. 129-136
-
-
Carling, D.1
Clarke, P.R.2
Zammit, V.A.3
Hardie, D.G.4
-
6
-
-
85047689953
-
5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells
-
Corton J.M., Gillespie J.G., Hawley S.A., Hardie D.G. (1995) 5-aminoimidazole-4-carboxamide ribonucleoside. A specific method for activating AMP-activated protein kinase in intact cells Eur J Biochem 229: 558-65.
-
(1995)
Eur J Biochem
, vol.229
, pp. 558-565
-
-
Corton, J.M.1
Gillespie, J.G.2
Hawley, S.A.3
Hardie, D.G.4
-
7
-
-
0029944966
-
Regulation of 5'-AMP-activated protein kinase activity by the noncatalytic beta and gamma subunits
-
Dyck J.R., Gao G., Widmer J., Stapleton D., Fernandez C.S., Kemp B.E., Witters L.A. (1996) Regulation of 5'-AMP-activated protein kinase activity by the noncatalytic beta and gamma subunits. J Biol Chem 271: 17798-803.
-
(1996)
J Biol Chem
, vol.271
, pp. 17798-17803
-
-
Dyck, J.R.1
Gao, G.2
Widmer, J.3
Stapleton, D.4
Fernandez, C.S.5
Kemp, B.E.6
Witters, L.A.7
-
8
-
-
0345107247
-
Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade
-
Hawley S.A., Boudeau J., Reid J.L., Mustard K.J., Udd L., Makela T.P., Alessi D.R., Hardie D.G. (2003) Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade. J Biol 2: 28
-
(2003)
J Biol
, vol.2
, pp. 28
-
-
Hawley, S.A.1
Boudeau, J.2
Reid, J.L.3
Mustard, K.J.4
Udd, L.5
Makela, T.P.6
Alessi, D.R.7
Hardie, D.G.8
-
9
-
-
10744230065
-
LKB1 is the upstream kinase in the AMP-activated protein kinase cascade
-
Woods A., Johnstone S.R., Dickerson K., Leiper F.C., Fryer L.G., Neumann D., Schlattner U., Wallimann T., Carlson M., Carling D. (2003) LKB1 is the upstream kinase in the AMP-activated protein kinase cascade. Curr Biol 13: 2004-8.
-
(2003)
Curr Biol
, vol.13
, pp. 2004-2008
-
-
Woods, A.1
Johnstone, S.R.2
Dickerson, K.3
Leiper, F.C.4
Fryer, L.G.5
Neumann, D.6
Schlattner, U.7
Wallimann, T.8
Carlson, M.9
Carling, D.10
-
10
-
-
23044432463
-
Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase
-
Hawley S.A., Pan D.A., Mustard K.J., Ross L., Bain J., Edelman A.M., Frenguelli B.G., Hardie D.G. (2005) Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase. Cell Metab 2: 9-19.
-
(2005)
Cell Metab
, vol.2
, pp. 9-19
-
-
Hawley, S.A.1
Pan, D.A.2
Mustard, K.J.3
Ross, L.4
Bain, J.5
Edelman, A.M.6
Frenguelli, B.G.7
Hardie, D.G.8
-
11
-
-
23044437445
-
Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells
-
Woods A., Dickerson K., Heath R., Hong S.P., Momcilovic M., Johnstone S.R., Carlson M., Carling D. (2005) Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells. Cell Metab 2: 21-33.
-
(2005)
Cell Metab
, vol.2
, pp. 21-33
-
-
Woods, A.1
Dickerson, K.2
Heath, R.3
Hong, S.P.4
Momcilovic, M.5
Johnstone, S.R.6
Carlson, M.7
Carling, D.8
-
12
-
-
0029910018
-
Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase
-
Hawley S.A., Davison M., Woods A., Davies S.P., Beri R.K., Carling D., Hardie D.G. (1996) Characterization of the AMP-activated protein kinase kinase from rat liver and identification of threonine 172 as the major site at which it phosphorylates AMP-activated protein kinase. J Biol Chem 271: 27879-87.
-
(1996)
J Biol Chem
, vol.271
, pp. 27879-27887
-
-
Hawley, S.A.1
Davison, M.2
Woods, A.3
Davies, S.P.4
Beri, R.K.5
Carling, D.6
Hardie, D.G.7
-
13
-
-
0023789884
-
Identification by amino acid sequencing of three major regulatory phosphorylation sites on rat acetyl-CoA carboxylase
-
Munday M.R., Campbell D.G., Carling D., Hardie D.G. (1988) Identification by amino acid sequencing of three major regulatory phosphorylation sites on rat acetyl-CoA carboxylase. Eur J Biochem 175: 331-8.
-
(1988)
Eur J Biochem
, vol.175
, pp. 331-338
-
-
Munday, M.R.1
Campbell, D.G.2
Carling, D.3
Hardie, D.G.4
-
14
-
-
0025310576
-
Regulation of HMG-CoA reductase: identification of the site phosphorylated by the AMP-activated protein kinase in vitro and in intact rat liver
-
Clarke P.R., Hardie D.G. (1990) Regulation of HMG-CoA reductase: identification of the site phosphorylated by the AMP-activated protein kinase in vitro and in intact rat liver. EMBO J 9: 2439-46.
-
(1990)
EMBO J
, vol.9
, pp. 2439-2446
-
-
Clarke, P.R.1
Hardie, D.G.2
-
15
-
-
0037143449
-
Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis
-
Horman S., Browne G., Krause U., Patel J., Vertommen D., Bertrand L., Lavoinne A., Hue L., Proud C., Rider M. (2002) Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis. Curr Biol 12: 1419-23.
-
(2002)
Curr Biol
, vol.12
, pp. 1419-1423
-
-
Horman, S.1
Browne, G.2
Krause, U.3
Patel, J.4
Vertommen, D.5
Bertrand, L.6
Lavoinne, A.7
Hue, L.8
Proud, C.9
Rider, M.10
-
16
-
-
0034074153
-
5-aminoimidazole-4-carboxamide riboside mimics the effects of insulin on the expression of the 2 key gluconeogenic genes PEPCK and glucose-6-phosphatase
-
Lochhead P.A., Salt I.P., Walker K.S., Hardie D.G., Sutherland C. (2000) 5-aminoimidazole-4-carboxamide riboside mimics the effects of insulin on the expression of the 2 key gluconeogenic genes PEPCK and glucose-6-phosphatase. Diabetes 49: 896-903.
-
(2000)
Diabetes
, vol.49
, pp. 896-903
-
-
Lochhead, P.A.1
Salt, I.P.2
Walker, K.S.3
Hardie, D.G.4
Sutherland, C.5
-
17
-
-
33646828975
-
Insulin antagonizes ischemia-induced Thr172 phosphorylation of AMP-activated protein kinase alpha-subunits in heart via hierarchical phosphorylation of Ser485/491
-
Horman S., Vertommen D., Heath R., Neumann D., Mouton V., Woods A., Schlattner U., Wallimann T., Carling D., Hue L., Rider M.H. (2006) Insulin antagonizes ischemia-induced Thr172 phosphorylation of AMP-activated protein kinase alpha-subunits in heart via hierarchical phosphorylation of Ser485/491. J Biol Chem 281: 5335-40.
-
(2006)
J Biol Chem
, vol.281
, pp. 5335-5340
-
-
Horman, S.1
Vertommen, D.2
Heath, R.3
Neumann, D.4
Mouton, V.5
Woods, A.6
Schlattner, U.7
Wallimann, T.8
Carling, D.9
Hue, L.10
Rider, M.H.11
-
18
-
-
64549151555
-
HCV replication suppresses cellular glucose uptake through down-regulation of cell surface expression of glucose transporters
-
Kasai D., Adachi T., Deng L., Nagano-Fujii M., Sada K., Ikeda M., Kato N., Ide Y.H., Shoji I., Hotta H. (2009) HCV replication suppresses cellular glucose uptake through down-regulation of cell surface expression of glucose transporters. J Hepatol 50: 883-94.
-
(2009)
J Hepatol
, vol.50
, pp. 883-894
-
-
Kasai, D.1
Adachi, T.2
Deng, L.3
Nagano-Fujii, M.4
Sada, K.5
Ikeda, M.6
Kato, N.7
Ide, Y.H.8
Shoji, I.9
Hotta, H.10
-
19
-
-
0036893332
-
Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication
-
Blight K.J., McKeating J.A., Rice C.M. (2002) Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication. J Virol 76: 13001-14.
-
(2002)
J Virol
, vol.76
, pp. 13001-13014
-
-
Blight, K.J.1
McKeating, J.A.2
Rice, C.M.3
-
20
-
-
67849133617
-
Efficient production of infectious hepatitis C virus with adaptive mutations in cultured hepatoma cells
-
Bungyoku Y., Shoji I., Makine T., Adachi T., Hayashida K., Nagano-Fujii M., Ide Y.H., Deng L., Hotta H. (2009) Efficient production of infectious hepatitis C virus with adaptive mutations in cultured hepatoma cells. J Gen Virol 90: 1681-91.
-
(2009)
J Gen Virol
, vol.90
, pp. 1681-1691
-
-
Bungyoku, Y.1
Shoji, I.2
Makine, T.3
Adachi, T.4
Hayashida, K.5
Nagano-Fujii, M.6
Ide, Y.H.7
Deng, L.8
Hotta, H.9
-
21
-
-
44649194072
-
Hepatitis C virus NS5A protein interacts with and negatively regulates the non-receptor protein tyrosine kinase Syk
-
Inubushi S., Nagano-Fujii M., Kitayama K., Tanaka M., An C., Yokozaki H., Yamamura H., Nuriya H., Kohara M., Sada K., Hotta H. (2008) Hepatitis C virus NS5A protein interacts with and negatively regulates the non-receptor protein tyrosine kinase Syk. J Gen Virol 89: 1231-42.
-
(2008)
J Gen Virol
, vol.89
, pp. 1231-1242
-
-
Inubushi, S.1
Nagano-Fujii, M.2
Kitayama, K.3
Tanaka, M.4
An, C.5
Yokozaki, H.6
Yamamura, H.7
Nuriya, H.8
Kohara, M.9
Sada, K.10
Hotta, H.11
-
22
-
-
23044437222
-
Complete replication of hepatitis C virus in cell culture
-
Lindenbach B.D., Evans M.J., Syder A.J., Wolk B., Tellinghuisen T.L., Liu C.C., Maruyama T., Hynes R.O., Burton D.R., McKeating J.A., Rice C.M. (2005) Complete replication of hepatitis C virus in cell culture. Science 309: 623-6.
-
(2005)
Science
, vol.309
, pp. 623-626
-
-
Lindenbach, B.D.1
Evans, M.J.2
Syder, A.J.3
Wolk, B.4
Tellinghuisen, T.L.5
Liu, C.C.6
Maruyama, T.7
Hynes, R.O.8
Burton, D.R.9
McKeating, J.A.10
Rice, C.M.11
-
23
-
-
71749117376
-
Tyrosine phosphorylation of 3BP2 regulates B cell receptor-mediated activation of NFAT
-
Shukla U., Hatani T., Nakashima K., Ogi K., Sada K. (2009) Tyrosine phosphorylation of 3BP2 regulates B cell receptor-mediated activation of NFAT. J Biol Chem 284: 33719-28.
-
(2009)
J Biol Chem
, vol.284
, pp. 33719-33728
-
-
Shukla, U.1
Hatani, T.2
Nakashima, K.3
Ogi, K.4
Sada, K.5
-
24
-
-
0037105464
-
Regulation of FcepsilonRI-mediated degranulation by an adaptor protein 3BP2 in rat basophilic leukemia RBL-2H3 cells
-
Sada K., Miah S.M., Maeno K., Kyo S., Qu X., Yamamura H. (2002) Regulation of FcepsilonRI-mediated degranulation by an adaptor protein 3BP2 in rat basophilic leukemia RBL-2H3 cells. Blood 100: 2138-44.
-
(2002)
Blood
, vol.100
, pp. 2138-2144
-
-
Sada, K.1
Miah, S.M.2
Maeno, K.3
Kyo, S.4
Qu, X.5
Yamamura, H.6
-
25
-
-
1442308053
-
Negative regulation of FcepsilonRI-mediated mast cell activation by a ubiquitin-protein ligase Cbl-b
-
Qu X., Sada K., Kyo S., Maeno K., Miah S.M., Yamamura H. (2004) Negative regulation of FcepsilonRI-mediated mast cell activation by a ubiquitin-protein ligase Cbl-b. Blood 103: 1779-86.
-
(2004)
Blood
, vol.103
, pp. 1779-1786
-
-
Qu, X.1
Sada, K.2
Kyo, S.3
Maeno, K.4
Miah, S.M.5
Yamamura, H.6
-
26
-
-
77954902957
-
Enhanced hepatitis C virus genome replication and lipid accumulation mediated by inhibition of AMP-activated protein kinase
-
Mankouri J., Tedbury P.R., Gretton S., Hughes M.E., Griffin S.D., Dallas M.L., Green K.A., Hardie D.G., Peers C., Harris M. (2010) Enhanced hepatitis C virus genome replication and lipid accumulation mediated by inhibition of AMP-activated protein kinase. Proc Natl Acad Sci U S A 107: 11549-54.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 11549-11554
-
-
Mankouri, J.1
Tedbury, P.R.2
Gretton, S.3
Hughes, M.E.4
Griffin, S.D.5
Dallas, M.L.6
Green, K.A.7
Hardie, D.G.8
Peers, C.9
Harris, M.10
-
27
-
-
0019400768
-
Aminoimidazole carboxamide ribonucleoside toxicity: a model for study of pyrimidine starvation
-
Thomas C.B., Meade J.C., Holmes E.W. (1981) Aminoimidazole carboxamide ribonucleoside toxicity: a model for study of pyrimidine starvation. J Cell Physiol 107: 335-44.
-
(1981)
J Cell Physiol
, vol.107
, pp. 335-344
-
-
Thomas, C.B.1
Meade, J.C.2
Holmes, E.W.3
-
28
-
-
85047279405
-
The enzymatic synthesis of 5-amino-4-imidazolecarboxamide riboside triphosphate (ZTP)
-
Sabina R.L., Holmes E.W., Becker M.A. (1984) The enzymatic synthesis of 5-amino-4-imidazolecarboxamide riboside triphosphate (ZTP). Science 223: 1193-5.
-
(1984)
Science
, vol.223
, pp. 1193-1195
-
-
Sabina, R.L.1
Holmes, E.W.2
Becker, M.A.3
-
29
-
-
0034659785
-
Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain
-
Owen M.R., Doran E., Halestrap A.P. (2000) Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain. Biochem J 348(Pt 3): 607-14.
-
(2000)
Biochem J
, vol.348
, Issue.PART 3
, pp. 607-614
-
-
Owen, M.R.1
Doran, E.2
Halestrap, A.P.3
-
30
-
-
0034614420
-
Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I
-
El-Mir M.Y., Nogueira V., Fontaine E., Averet N., Rigoulet M., Leverve X. (2000) Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I. J Biol Chem 275: 223-8.
-
(2000)
J Biol Chem
, vol.275
, pp. 223-228
-
-
El-Mir, M.Y.1
Nogueira, V.2
Fontaine, E.3
Averet, N.4
Rigoulet, M.5
Leverve, X.6
-
31
-
-
77954933558
-
Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state
-
Foretz M., Hebrard S., Leclerc J., Zarrinpashneh E., Soty M., Mithieux G., Sakamoto K., Andreelli F., Viollet B. (2010) Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state. Clin Invest 120: 2355-69.
-
(2010)
Clin Invest
, vol.120
, pp. 2355-2369
-
-
Foretz, M.1
Hebrard, S.2
Leclerc, J.3
Zarrinpashneh, E.4
Soty, M.5
Mithieux, G.6
Sakamoto, K.7
Andreelli, F.8
Viollet, B.9
-
32
-
-
7244243810
-
Hepatitis C virus down-regulates insulin receptor substrates 1 and 2 through up-regulation of suppressor of cytokine signaling 3
-
Kawaguchi T., Yoshida T., Harada M., Hisamoto T., Nagao Y., Ide T., Taniguchi E., Kumemura H., Hanada S., Maeyama M., Baba S., Koga H., Kumashiro R., Ueno T., Ogata H., Yoshimura A., Sata M. (2004) Hepatitis C virus down-regulates insulin receptor substrates 1 and 2 through up-regulation of suppressor of cytokine signaling 3. Am J Pathol 165: 1499-508.
-
(2004)
Am J Pathol
, vol.165
, pp. 1499-1508
-
-
Kawaguchi, T.1
Yoshida, T.2
Harada, M.3
Hisamoto, T.4
Nagao, Y.5
Ide, T.6
Taniguchi, E.7
Kumemura, H.8
Hanada, S.9
Maeyama, M.10
Baba, S.11
Koga, H.12
Kumashiro, R.13
Ueno, T.14
Ogata, H.15
Yoshimura, A.16
Sata, M.17
-
33
-
-
33847316067
-
Clearance of HCV improves insulin resistance, beta-cell function, and hepatic expression of insulin receptor substrate 1 and 2
-
Kawaguchi T., Ide T., Taniguchi E., Hirano E., Itou M., Sumie S., Nagao Y., Yanagimoto C., Hanada S., Koga H., Sata M. (2007) Clearance of HCV improves insulin resistance, beta-cell function, and hepatic expression of insulin receptor substrate 1 and 2. Am J Gastroenterol 102: 570-6.
-
(2007)
Am J Gastroenterol
, vol.102
, pp. 570-576
-
-
Kawaguchi, T.1
Ide, T.2
Taniguchi, E.3
Hirano, E.4
Itou, M.5
Sumie, S.6
Nagao, Y.7
Yanagimoto, C.8
Hanada, S.9
Koga, H.10
Sata, M.11
-
34
-
-
0036851817
-
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
-
Yamauchi T., Kamon J., Minokoshi Y., Ito Y., Waki H., Uchida S., Yamashita S., Noda M., Kita S., Ueki K., Eto K., Akanuma Y., Froguel P., Foufelle F., Ferre P., Carling D., Kimura S., Nagai R., Kahn B.B., Kadowaki T. (2002) Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med 8: 1288-95.
-
(2002)
Nat Med
, vol.8
, pp. 1288-1295
-
-
Yamauchi, T.1
Kamon, J.2
Minokoshi, Y.3
Ito, Y.4
Waki, H.5
Uchida, S.6
Yamashita, S.7
Noda, M.8
Kita, S.9
Ueki, K.10
Eto, K.11
Akanuma, Y.12
Froguel, P.13
Foufelle, F.14
Ferre, P.15
Carling, D.16
Kimura, S.17
Nagai, R.18
Kahn, B.B.19
Kadowaki, T.20
more..
-
35
-
-
0346374720
-
Pioglitazone treatment activates AMP-activated protein kinase in rat liver and adipose tissue in vivo
-
Saha A.K., Avilucea P.R., Ye J.M., Assifi M.M., Kraegen E.W., Ruderman N.B. (2004) Pioglitazone treatment activates AMP-activated protein kinase in rat liver and adipose tissue in vivo. Biochem Biophys Res Commun 314: 580-5.
-
(2004)
Biochem Biophys Res Commun
, vol.314
, pp. 580-585
-
-
Saha, A.K.1
Avilucea, P.R.2
Ye, J.M.3
Assifi, M.M.4
Kraegen, E.W.5
Ruderman, N.B.6
-
36
-
-
0034773404
-
Role of AMP-activated protein kinase in mechanism of metformin action
-
Zhou G., Myers R., Li Y., Chen Y., Shen X., Fenyk-Melody J., Wu M., Ventre J., Doebber T., Fujii N., Musi N., Hirshman M.F., Goodyear L.J., Moller D.E. (2001) Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest 108: 1167-74.
-
(2001)
J Clin Invest
, vol.108
, pp. 1167-1174
-
-
Zhou, G.1
Myers, R.2
Li, Y.3
Chen, Y.4
Shen, X.5
Fenyk-Melody, J.6
Wu, M.7
Ventre, J.8
Doebber, T.9
Fujii, N.10
Musi, N.11
Hirshman, M.F.12
Goodyear, L.J.13
Moller, D.E.14
-
37
-
-
34548316984
-
The lipid droplet is an important organelle for hepatitis C virus production
-
Miyanari Y., Atsuzawa K., Usuda N., Watashi K., Hishiki T., Zayas M., Bartenschlager R., Wakita T., Hijikata M., Shimotohno K. (2007) The lipid droplet is an important organelle for hepatitis C virus production. Nature Cell Biology 9: 1089-97.
-
(2007)
Nature Cell Biology
, vol.9
, pp. 1089-1097
-
-
Miyanari, Y.1
Atsuzawa, K.2
Usuda, N.3
Watashi, K.4
Hishiki, T.5
Zayas, M.6
Bartenschlager, R.7
Wakita, T.8
Hijikata, M.9
Shimotohno, K.10
-
38
-
-
1942489017
-
Anti-HCV activities of selective polyunsaturated fatty acids
-
Leu G.Z., Lin T.Y., Hsu J.T. (2004) Anti-HCV activities of selective polyunsaturated fatty acids. Biochem Biophys Res Commun 318: 275-80.
-
(2004)
Biochem Biophys Res Commun
, vol.318
, pp. 275-280
-
-
Leu, G.Z.1
Lin, T.Y.2
Hsu, J.T.3
-
39
-
-
14044265120
-
Hepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acids
-
Kapadia S.B., Chisari F.V. (2005) Hepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acids. Proc Natl Acad Sci U S A 102: 2561-6.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 2561-2566
-
-
Kapadia, S.B.1
Chisari, F.V.2
-
40
-
-
0346103657
-
Disruption of hepatitis C virus RNA replication through inhibition of host protein geranylgeranylation
-
Ye J., Wang C., Sumpter R. Jr., Brown M.S., Goldstein J.L., Gale M. Jr. (2003) Disruption of hepatitis C virus RNA replication through inhibition of host protein geranylgeranylation. Proc Natl Acad Sci U S A 100: 15865-70.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 15865-15870
-
-
Ye, J.1
Wang, C.2
Sumpter Jr, R.3
Brown, M.S.4
Goldstein, J.L.5
Gale Jr, M.6
-
41
-
-
0035148546
-
Characterization of cell lines carrying self-replicating hepatitis C virus RNAs
-
Pietschmann T., Lohmann V., Rutter G., Kurpanek K., Bartenschlager R. (2001) Characterization of cell lines carrying self-replicating hepatitis C virus RNAs. J Virol 75: 1252-64.
-
(2001)
J Virol
, vol.75
, pp. 1252-1264
-
-
Pietschmann, T.1
Lohmann, V.2
Rutter, G.3
Kurpanek, K.4
Bartenschlager, R.5
-
42
-
-
0041888351
-
Replication of hepatitis C virus subgenomes in nonhepatic epithelial and mouse hepatoma cells
-
Zhu Q., Guo J.T., Seeger C. (2003) Replication of hepatitis C virus subgenomes in nonhepatic epithelial and mouse hepatoma cells. J Virol 77: 9204-10.
-
(2003)
J Virol
, vol.77
, pp. 9204-9210
-
-
Zhu, Q.1
Guo, J.T.2
Seeger, C.3
-
43
-
-
77954365681
-
Metformin and reduced risk of hepatocellular carcinoma in diabetic patients with chronic liver disease
-
Donadon V., Balbi M., Mas M.D., Casarin P., Zanette G. (2010) Metformin and reduced risk of hepatocellular carcinoma in diabetic patients with chronic liver disease. Liver Int 30: 750-8.
-
(2010)
Liver Int
, vol.30
, pp. 750-758
-
-
Donadon, V.1
Balbi, M.2
Mas, M.D.3
Casarin, P.4
Zanette, G.5
-
44
-
-
72549104493
-
Treatment of insulin resistance with metformin in naive genotype 1 chronic hepatitis C patients receiving peginterferon alfa-2a plus ribavirin
-
Romero-Gomez M., Diago M., Andrade R.J., Calleja J.L., Salmeron J., Fernandez-Rodriguez C.M., Sola R., Garcia-Samaniego J., Herrerias J.M., De la Mata M., Moreno-Otero R., Nunez O., Olveira A., Duran S., Planas R. (2009) Treatment of insulin resistance with metformin in naive genotype 1 chronic hepatitis C patients receiving peginterferon alfa-2a plus ribavirin. Hepatology 50: 1702-8.
-
(2009)
Hepatology
, vol.50
, pp. 1702-1708
-
-
Romero-Gomez, M.1
Diago, M.2
Andrade, R.J.3
Calleja, J.L.4
Salmeron, J.5
Fernandez-Rodriguez, C.M.6
Sola, R.7
Garcia-Samaniego, J.8
Herrerias, J.M.9
De la Mata, M.10
Moreno-Otero, R.11
Nunez, O.12
Olveira, A.13
Duran, S.14
Planas, R.15
|