Abnormal sympathetic reactivity to the cold pressor test in overweight humans

American Journal of Hypertension

Volumn 25, Issue 12, 2012, Pages 1236-1241

  Park, Jeanie ^a,b   Middlekauff, Holly R ^c   Campese, Vito M ^d  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ATLANTA VA MEDICAL CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

blood pressure; hypertension; overweight; physiological stress response; sympathetic nervous system

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; COLD PRESSOR TEST; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DISEASE PREDISPOSITION; FEMALE; HAND GRIP; HUMAN; MALE; NEUROGRAPHY; NEUROLOGIC DISEASE; OBESITY; PRIORITY JOURNAL; SYMPATHETIC REFLEX; SYSTOLIC BLOOD PRESSURE;

ADULT; BLOOD PRESSURE; BODY MASS INDEX; CASE-CONTROL STUDIES; COLD-SHOCK RESPONSE; EXERCISE TEST; FEMALE; HAND STRENGTH; HEART; HEART RATE; HUMANS; HYPERTENSION; MALE; MUSCLE, SKELETAL; OVERWEIGHT; PREDICTIVE VALUE OF TESTS; RISK FACTORS; SYMPATHETIC NERVOUS SYSTEM;

EID: 84869229488     PISSN: 08957061     EISSN: 19417225     Source Type: Journal    
DOI: 10.1038/ajh.2012.115     Document Type: Article

References (39)

1. Yan LL, Daviglus ML, Liu K, Stamler J, Wang R, Pirzada A, Garside DB, Dyer AR, Van Horn L, Liao Y, Fries JF, Greenland P. Midlife body mass index and hospitalization and mortality in older age. JAMA 2006; 295:190-198. (Pubitemid 43076438)
2. Garrison RJ, Kannel WB, Stokes J 3rd, Castelli WP. Incidence and precursors of hypertension in young adults: the Framingham Offspring Study. Prev Med 1987; 16:235-251. (Pubitemid 17067798)
3. Matsukawa T, Gotoh E, Uneda S, Miyajima E, Shionoiri H, Tochikubo O, Ishii M. Augmented sympathetic nerve activity in response to stressors in young borderline hypertensive men. Acta Physiol Scand 1991; 141:157-165.
4. Calhoun DA, Mutinga ML. Race, family history of hypertension, and sympathetic response to cold pressor testing. Blood Press 1997; 6:209-213. (Pubitemid 27368486)
5. Matthews KA, Woodall KL, Allen MT. Cardiovascular reactivity to stress predicts future blood pressure status. Hypertension 1993; 22:479-485. (Pubitemid 23292153)
6. Matthews KA, Salomon K, Brady SS, Allen MT. Cardiovascular reactivity to stress predicts future blood pressure in adolescence. Psychosom Med 2003; 65:410-415. (Pubitemid 36628894)
7. Steptoe A, Marmot M. Impaired cardiovascular recovery following stress predicts 3-year increases in blood pressure. J Hypertens 2005; 23:529-536. (Pubitemid 40684710)
8. Victor RG, Leimbach WN Jr, Seals DR, Wallin BG, Mark AL. Effects of the cold pressor test on muscle sympathetic nerve activity in humans. Hypertension 1987; 9:429-436. (Pubitemid 17068758)
9. Treiber FA, Kamarck T, Schneiderman N, Sheffield D, Kapuku G, Taylor T. Cardiovascular reactivity and development of preclinical and clinical disease states. Psychosom Med 2003; 65:46-62. (Pubitemid 36143196)
10. Grassi G, Facchini A, Trevano FQ, Dell'Oro R, Arenare F, Tana F, Bolla G, Monzani A, Robuschi M, Mancia G. Obstructive sleep apnea-dependent and-independent adrenergic activation in obesity. Hypertension 2005; 46:321-325. (Pubitemid 41099164)
11. Alvarez GE, Beske SD, Ballard TP, Davy KP. Sympathetic neural activation in visceral obesity. Circulation 2002; 106:2533-2536. (Pubitemid 35340687)
12. Grassi G, Seravalle G, Dell'Oro R, Turri C, Bolla GB, Mancia G. Adrenergic and reflex abnormalities in obesity-related hypertension. Hypertension 2000; 36:538-542.
13. Mano T, Iwase S, Toma S. Microneurography as a tool in clinical neurophysiology to investigate peripheral neural traffic in humans. Clin Neurophysiol 2006; 117:2357-2384. (Pubitemid 44548487)
14. Delius W, Hagbarth KE, Hongell A, Wallin BG. General characteristics of sympathetic activity in human muscle nerves. Acta Physiol Scand 1972; 84:65-81.
15. Delius W, Hagbarth KE, Hongell A, Wallin BG. Manoeuvres affecting sympathetic outflow in human muscle nerves. Acta Physiol Scand 1972; 84:82-94.
16. Mark AL, Victor RG, Nerhed C, Wallin BG. Microneurographic studies of the mechanisms of sympathetic nerve responses to static exercise in humans. Circ Res 1985; 57:461-469. (Pubitemid 16217989)
17. Ogden CL, Carroll MD, Curtin LR, McDowell MA, Tabak CJ, Flegal KM. Prevalence of overweight and obesity in the United States, 1999-2004. JAMA 2006; 295:1549-1555.
18. Fontaine KR, Redden DT, Wang C, Westfall AO, Allison DB. Years of life lost due to obesity. JAMA 2003; 289:187-193. (Pubitemid 36068706)
19. Morgan DA, Anderson EA, Mark AL. Renal sympathetic nerve activity is increased in obese Zucker rats. Hypertension 1995; 25:834-838.
20. Kuniyoshi FH, Trombetta IC, Batalha LT, Rondon MU, Laterza MC, Gowdak MM, Barretto AC, Halpern A, Villares SM, Lima EG, Negrão CE. Abnormal neurovascular control during sympathoexcitation in obesity. Obes Res 2003; 11:1411-1419. (Pubitemid 41127364)
21. Eikelis N, Esler M. The neurobiology of human obesity. Exp Physiol 2005; 90:673-682. (Pubitemid 41406055)
22. Grassi G, Dell'Oro R, Facchini A, Quarti Trevano F, Bolla GB, Mancia G. Effect of central and peripheral body fat distribution on sympathetic and baroreflex function in obese normotensives. J Hypertens 2004; 22:2363-2369. (Pubitemid 39620287)
23. Grassi G, Cattaneo BM, Seravalle G, Colombo M, Cavagnini F, Mancia G. Obesity and the sympathetic nervous system. Blood Press Suppl 1996; 1:43-46. (Pubitemid 26145370)
24. Huggett RJ, Burns J, Mackintosh AF, Mary DA. Sympathetic neural activation in nondiabetic metabolic syndrome and its further augmentation by hypertension. Hypertension 2004; 44:847-852. (Pubitemid 39577410)
25. Grassi G, Seravalle G, Quarti-Trevano F, Scopelliti F, Dell'Oro R, Bolla G, Mancia G. Excessive sympathetic activation in heart failure with obesity and metabolic syndrome: characteristics and mechanisms. Hypertension 2007; 49:535-541.
26. Grassi G, Seravalle G, Quarti-Trevano F, Dell'Oro R, Bolla G, Mancia G. Effects of hypertension and obesity on the sympathetic activation of heart failure patients. Hypertension 2003; 42:873-877. (Pubitemid 37413723)
27. Abate NI, Mansour YH, Tuncel M, Arbique D, Chavoshan B, Kizilbash A, Howell-Stampley T, Vongpatanasin W, Victor RG. Overweight and sympathetic overactivity in black Americans. Hypertension 2001; 38:379-383. (Pubitemid 34225669)
28. Lambert E, Straznicky N, Eikelis N, Esler M, Dawood T, Masuo K, Schlaich M, Lambert G. Gender differences in sympathetic nervous activity: influence of body mass and blood pressure. J Hypertens 2007; 25:1411-1419. (Pubitemid 46918828)
29. Jones PP, Snitker S, Skinner JS, Ravussin E. Gender differences in muscle sympathetic nerve activity: effect of body fat distribution. Am J Physiol 1996; 270:E363-E366.
30. Negrão CE, Trombetta IC, Batalha LT, Ribeiro MM, Rondon MU, Tinucci T, Forjaz CL, Barretto AC, Halpern A, Villares SM. Muscle metaboreflex control is diminished in normotensive obese women. Am J Physiol Heart Circ Physiol 2001; 281:H469-H475.
31. Wood DL, Sheps SG, Elveback LR, Schirger A. Cold pressor test as a predictor of hypertension. Hypertension 1984; 6:301-306. (Pubitemid 14091456)
32. Calhoun DA, Mutinga ML, Collins AS, Wyss JM, Oparil S. Normotensive blacks have heightened sympathetic response to cold pressor test. Hypertension 1993; 22:801-805. (Pubitemid 23358085)
33. Pasini FL, Capecchi PL, Colafati M, Randisi P, Puccetti L, Di Perri T. Systemic adenosine increase during cold pressor test is dependent on sympathetic activation. Clin Exp Pharmacol Physiol 1999; 26:774-778. (Pubitemid 29476990)
34. Park J, Campese VM, Middlekauff HR. Exercise pressor reflex in humans with end-stage renal disease. Am J Physiol Regul Integr Comp Physiol 2008; 295:R1188-R1194.
35. Delaney EP, Greaney JL, Edwards DG, Rose WC, Fadel PJ, Farquhar WB. Exaggerated sympathetic and pressor responses to handgrip exercise in older hypertensive humans: role of the muscle metaboreflex. Am J Physiol Heart Circ Physiol 2010; 299:H1318-H1327.
36. Seals DR, Victor RG. Regulation of muscle sympathetic nerve activity during exercise in humans. Exerc Sport Sci Rev 1991; 19:313-349.
37. Seals DR, Victor RG, Mark AL. Plasma norepinephrine and muscle sympathetic discharge during rhythmic exercise in humans. J Appl Physiol 1988; 65:940-944.
38. Wallin BG, Thompson JM, Jennings GL, Esler MD. Renal noradrenaline spillover correlates with muscle sympathetic activity in humans. J Physiol (Lond) 1996; 491 (Pt 3):881-887. (Pubitemid 26107257)
39. Wallin BG, Esler M, Dorward P, Eisenhofer G, Ferrier C, Westerman R, Jennings G. Simultaneous measurements of cardiac noradrenaline spillover and sympathetic outflow to skeletal muscle in humans. J Physiol (Lond) 1992; 453:45-58.