-
1
-
-
79952232216
-
Global cancer statistics
-
Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin. 2011;61(2):69-90.
-
(2011)
CA Cancer J Clin
, vol.61
, Issue.2
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Ferlay, J.3
Ward, E.4
Forman, D.5
-
2
-
-
84856050530
-
Heterogeneity of breast cancer: Etiology and clinical relevance
-
Almendro V, Fuster G. Heterogeneity of breast cancer: etiology and clinical relevance. Clin Transl Oncol. 2011;13(11):767-773.
-
(2011)
Clin Transl Oncol
, vol.13
, Issue.11
, pp. 767-773
-
-
Almendro, V.1
Fuster, G.2
-
3
-
-
1842561379
-
Lobular Neoplasia
-
In Tavassoli FA, Devilee P. et al Lyon, France: IARC Press
-
Tavassoli FA, Millis RR, Boecker W, Lakhani SR. Lobular Neoplasia. In Tavassoli FA, Devilee P. et al. World Health Organization Classification of Tumours. Lyon, France: IARC Press; 2003:60-62.
-
(2003)
World Health Organization Classification of Tumours
, pp. 60-62
-
-
Tavassoli, F.A.1
Millis, R.R.2
Boecker, W.3
Lakhani, S.R.4
-
4
-
-
81555216077
-
Gene expression profiling in breast cancer: Classification, prognostication, and prediction
-
Reis-Filho JS, Pusztai L. Gene expression profiling in breast cancer: classification, prognostication, and prediction. Lancet. 2011; 378(9805):1812-1823.
-
(2011)
Lancet
, vol.378
, Issue.9805
, pp. 1812-1823
-
-
Reis-Filho, J.S.1
Pusztai, L.2
-
5
-
-
79952111066
-
Chromatin remodeling in mammary gland differentiation and breast tumorigenesis
-
Huang TH, Esteller M. Chromatin remodeling in mammary gland differentiation and breast tumorigenesis. Cold Spring Harb Perspect Biol. 2010;2(9):a004515.
-
(2010)
Cold Spring Harb Perspect Biol
, vol.2
, Issue.9
-
-
Huang, T.H.1
Esteller, M.2
-
6
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011;144(5):646-674.
-
(2011)
Cell
, vol.144
, Issue.5
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
7
-
-
0035845511
-
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
-
Sorlie T, Perou CM, Tibshirani R, et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci U S A. 2001;98(19):10869-10874.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, Issue.19
, pp. 10869-10874
-
-
Sorlie, T.1
Perou, C.M.2
Tibshirani, R.3
-
8
-
-
0037478605
-
Repeated observation of breast tumor subtypes in independent gene expression data sets
-
Sorlie T, Tibshirani R, Parker J, et al. Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc Natl Acad Sci U S A. 2003;100(14):8418-8423.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.14
, pp. 8418-8423
-
-
Sorlie, T.1
Tibshirani, R.2
Parker, J.3
-
9
-
-
0042838307
-
Breast cancer classification and prognosis based on gene expression profiles from a population-based study
-
Sotiriou C, Neo SY, McShane LM, et al. Breast cancer classification and prognosis based on gene expression profiles from a population-based study. Proc Natl Acad Sci U S A. 2003;100(18):10393-10398.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.18
, pp. 10393-10398
-
-
Sotiriou, C.1
Neo, S.Y.2
McShane, L.M.3
-
10
-
-
0034680102
-
Molecular portraits of human breast tumours
-
Perou CM, Sorlie T, Eisen MB, et al. Molecular portraits of human breast tumours. Nature. 2000;406(6797):747-752.
-
(2000)
Nature
, vol.406
, Issue.6797
, pp. 747-752
-
-
Perou, C.M.1
Sorlie, T.2
Eisen, M.B.3
-
11
-
-
33745948105
-
Intrinsic molecular signature of breast cancer in a population-based cohort of 412 patients
-
Calza S, Hall P, Auer G, et al. Intrinsic molecular signature of breast cancer in a population-based cohort of 412 patients. Breast Cancer Res. 2006;8(4):R34.
-
(2006)
Breast Cancer Res
, vol.8
, Issue.4
-
-
Calza, S.1
Hall, P.2
Auer, G.3
-
12
-
-
78951482208
-
Deconstructing the molecular portraits of breast cancer
-
Prat A, Perou CM. Deconstructing the molecular portraits of breast cancer. Mol Oncol. 2011;5(1):5-23.
-
(2011)
Mol Oncol
, vol.5
, Issue.1
, pp. 5-23
-
-
Prat, A.1
Perou, C.M.2
-
13
-
-
77953873374
-
Triplenegative breast cancer: Present challenges and new perspectives
-
for FEMME Consortium
-
Podo F, Buydens LM, Degani H, et al; for FEMME Consortium. Triplenegative breast cancer: present challenges and new perspectives. Mol Oncol. 2010;4(3):209-229.
-
(2010)
Mol Oncol
, vol.4
, Issue.3
, pp. 209-229
-
-
Podo, F.1
Buydens, L.M.2
Degani, H.3
-
14
-
-
84861527388
-
The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
-
for METABRIC Group
-
Curtis C, Shah SP, Chin SF, et al; for METABRIC Group. The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups. Nature. 2012;486(7403):346-352.
-
(2012)
Nature
, vol.486
, Issue.7403
, pp. 346-352
-
-
Curtis, C.1
Shah, S.P.2
Chin, S.F.3
-
15
-
-
84863116790
-
Defining the cellular precursors to human breast cancer
-
Keller PJ, Arendt LM, Skibinski A, et al. Defining the cellular precursors to human breast cancer. Proc Natl Acad Sci U S A. 2012;109(8): 2772-2777.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.8
, pp. 2772-2777
-
-
Keller, P.J.1
Arendt, L.M.2
Skibinski, A.3
-
16
-
-
68349130357
-
Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
-
Lim E, Vaillant F, Wu D, et al. Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers. Nat Med. 2009;15(8):907-913.
-
(2009)
Nat Med
, vol.15
, Issue.8
, pp. 907-913
-
-
Lim, E.1
Vaillant, F.2
Wu, D.3
-
17
-
-
77956218241
-
BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells
-
Molyneux G, Geyer FC, Magnay FA, et al. BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells. Cell Stem Cell. 2010;7(3):403-417.
-
(2010)
Cell Stem Cell
, vol.7
, Issue.3
, pp. 403-417
-
-
Molyneux, G.1
Geyer, F.C.2
Magnay, F.A.3
-
18
-
-
7444264020
-
The origins of estrogen receptor alphapositive and estrogen receptor alpha-negative human breast cancer
-
Allred DC, Brown P, Medina D. The origins of estrogen receptor alphapositive and estrogen receptor alpha-negative human breast cancer. Breast Cancer Res. 2004;6(6):240-245.
-
(2004)
Breast Cancer Res
, vol.6
, Issue.6
, pp. 240-245
-
-
Allred, D.C.1
Brown, P.2
Medina, D.3
-
19
-
-
84869209828
-
Stem cell plasticity in development and cancer: Epigenetic origin of cancer stem cells
-
Kundu TK, editor, Springer: Subcellular Biochemistry
-
Shah M, Allegrucci C. Stem cell plasticity in development and cancer: epigenetic origin of cancer stem cells. In: Kundu TK, editor. Epigenetics: Development and Disease. Springer: Subcellular Biochemistry; 2012:61.
-
(2012)
Epigenetics: Development and Disease
, pp. 61
-
-
Shah, M.1
Allegrucci, C.2
-
20
-
-
52549087785
-
Cancer stem cells in solid tumours: Accumulating evidence and unresolved questions
-
Visvader JE, Lindeman GJ. Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat Rev Cancer. 2008;8(10):755-768.
-
(2008)
Nat Rev Cancer
, vol.8
, Issue.10
, pp. 755-768
-
-
Visvader, J.E.1
Lindeman, G.J.2
-
21
-
-
84855332744
-
Breast-cancer stem cells-beyond semantics
-
Badve S, Nakshatri H. Breast-cancer stem cells-beyond semantics. Lancet Oncol. 2012;13(1):e43-e48.
-
(2012)
Lancet Oncol
, vol.13
, Issue.1
-
-
Badve, S.1
Nakshatri, H.2
-
22
-
-
30144432901
-
Purification and unique properties of mammary epithelial stem cells
-
Stingl J, Eirew P, Ricketson I, et al. Purification and unique properties of mammary epithelial stem cells. Nature. 2006;439(7079):993-997.
-
(2006)
Nature
, vol.439
, Issue.7079
, pp. 993-997
-
-
Stingl, J.1
Eirew, P.2
Ricketson, I.3
-
23
-
-
30144433093
-
Generation of a functional mammary gland from a single stem cell
-
Shackleton M, Vaillant F, Simpson KJ, et al. Generation of a functional mammary gland from a single stem cell. Nature. 2006; 439(7072):84-88.
-
(2006)
Nature
, vol.439
, Issue.7072
, pp. 84-88
-
-
Shackleton, M.1
Vaillant, F.2
Simpson, K.J.3
-
24
-
-
80855130470
-
Distinct stem cells contribute to mammary gland development and maintenance
-
Van Keymeulen A, Rocha AS, Ousset M, et al. Distinct stem cells contribute to mammary gland development and maintenance. Nature. 2011;479(7372):189-193.
-
(2011)
Nature
, vol.479
, Issue.7372
, pp. 189-193
-
-
van Keymeulen, A.1
Rocha, A.S.2
Ousset, M.3
-
25
-
-
57349148680
-
A method for quantifying normal human mammary epithelial stem cells with in vivo regenerative ability
-
Eirew P, Stingl J, Raouf A, et al. A method for quantifying normal human mammary epithelial stem cells with in vivo regenerative ability. Nat Med. 2008;14(12):1384-1389.
-
(2008)
Nat Med
, vol.14
, Issue.12
, pp. 1384-1389
-
-
Eirew, P.1
Stingl, J.2
Raouf, A.3
-
26
-
-
84863858993
-
The biology of human breast epithelial progenitors
-
Raouf A, Sun Y, Chatterjee S, Basak P. The biology of human breast epithelial progenitors. Semin Cell Dev Biol. 2012;23(5):606-612.
-
(2012)
Semin Cell Dev Biol
, vol.23
, Issue.5
, pp. 606-612
-
-
Raouf, A.1
Sun, Y.2
Chatterjee, S.3
Basak, P.4
-
27
-
-
84865203983
-
A restricted cell population propagates glioblastoma growth after chemotherapy
-
Chen J, Li Y, Yu TS, et al. A restricted cell population propagates glioblastoma growth after chemotherapy. Nature. 2012;488(7412):522-526.
-
(2012)
Nature
, vol.488
, Issue.7412
, pp. 522-526
-
-
Chen, J.1
Li, Y.2
Yu, T.S.3
-
28
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF. Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci U S A. 2003;100(7):3983-3988.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.7
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
29
-
-
33847419142
-
Molecular definition of breast tumor heterogeneity
-
Shipitsin M, Campbell LL, Argani P, et al. Molecular definition of breast tumor heterogeneity. Cancer Cell. Mar 2007;11(3):259-273.
-
(2007)
Cancer Cell
, vol.11
, Issue.3
, pp. 259-273
-
-
Shipitsin, M.1
Campbell, L.L.2
Argani, P.3
-
30
-
-
21344454219
-
Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties
-
Ponti D, Costa A, Zaffaroni N, et al. Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties. Cancer Res. 2005;65(13):5506-5511.
-
(2005)
Cancer Res
, vol.65
, Issue.13
, pp. 5506-5511
-
-
Ponti, D.1
Costa, A.2
Zaffaroni, N.3
-
31
-
-
48949119473
-
Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy
-
Fillmore CM, Kuperwasser C. Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy. Breast Cancer Res. 2008;10(2):R25.
-
(2008)
Breast Cancer Res
, vol.10
, Issue.2
-
-
Fillmore, C.M.1
Kuperwasser, C.2
-
32
-
-
35848955428
-
ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome
-
Ginestier C, Hur MH, Charafe-Jauffret E, et al. ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell. 2007;1(5):555-567.
-
(2007)
Cell Stem Cell
, vol.1
, Issue.5
, pp. 555-567
-
-
Ginestier, C.1
Hur, M.H.2
Charafe-Jauffret, E.3
-
33
-
-
84856088648
-
Aldehyde dehydrogenase activity is a biomarker of primitive normal human mammary luminal cells
-
Eirew P, Kannan N, Knapp DJ, et al. Aldehyde dehydrogenase activity is a biomarker of primitive normal human mammary luminal cells. Stem Cells. 2012;30(2):344-348.
-
(2012)
Stem Cells
, vol.30
, Issue.2
, pp. 344-348
-
-
Eirew, P.1
Kannan, N.2
Knapp, D.J.3
-
34
-
-
0037948854
-
In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
-
Dontu G, Abdallah WM, Foley JM, et al. In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes Dev. 2003;17(10):1253-1270.
-
(2003)
Genes Dev
, vol.17
, Issue.10
, pp. 1253-1270
-
-
Dontu, G.1
Abdallah, W.M.2
Foley, J.M.3
-
35
-
-
78549254600
-
Breast cancer stem cells: Something out of notching?
-
Harrison H, Farnie G, Brennan KR, Clarke RB. Breast cancer stem cells: something out of notching? Cancer Res. 2010;70(22):8973-8976.
-
(2010)
Cancer Res
, vol.70
, Issue.22
, pp. 8973-8976
-
-
Harrison, H.1
Farnie, G.2
Brennan, K.R.3
Clarke, R.B.4
-
36
-
-
73149110562
-
Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content
-
Pece S, Tosoni D, Confalonieri S, et al. Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content. Cell. 2010;140(1):62-73.
-
(2010)
Cell
, vol.140
, Issue.1
, pp. 62-73
-
-
Pece, S.1
Tosoni, D.2
Confalonieri, S.3
-
38
-
-
84865222310
-
Defining the mode of tumour growth by clonal analysis
-
Driessens G, Beck B, Caauwe A, Simons BD, Blanpain C. Defining the mode of tumour growth by clonal analysis. Nature. 2012;488(7412): 527-530.
-
(2012)
Nature
, vol.488
, Issue.7412
, pp. 527-530
-
-
Driessens, G.1
Beck, B.2
Caauwe, A.3
Simons, B.D.4
Blanpain, C.5
-
39
-
-
79551614327
-
Genetic predisposition directs breast cancer phenotype by dictating progenitor cell fate
-
Proia TA, Keller PJ, Gupta PB, et al. Genetic predisposition directs breast cancer phenotype by dictating progenitor cell fate. Cell Stem Cell. 2011;8(2):149-163.
-
(2011)
Cell Stem Cell
, vol.8
, Issue.2
, pp. 149-163
-
-
Proia, T.A.1
Keller, P.J.2
Gupta, P.B.3
-
40
-
-
78751676408
-
Cells of origin in cancer
-
Visvader JE. Cells of origin in cancer. Nature. 2011;469(7330): 314-322.
-
(2011)
Nature
, vol.469
, Issue.7330
, pp. 314-322
-
-
Visvader, J.E.1
-
41
-
-
84864854371
-
Lineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas
-
Schepers AG, Snippert HJ, Stange DE, et al. Lineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas. Science. 2012;337(6095):730-735.
-
(2012)
Science
, vol.337
, Issue.6095
, pp. 730-735
-
-
Schepers, A.G.1
Snippert, H.J.2
Stange, D.E.3
-
42
-
-
84865238272
-
Cancer: Resolving the stem-cell debate
-
Gilbertson RJ, Graham TA. Cancer: Resolving the stem-cell debate. Nature. 2012;488(7412):462-463.
-
(2012)
Nature
, vol.488
, Issue.7412
, pp. 462-463
-
-
Gilbertson, R.J.1
Graham, T.A.2
-
43
-
-
35148900228
-
The fuzzy math of solid tumor stem cells: A perspective
-
Kern SE, Shibata D. The fuzzy math of solid tumor stem cells: a perspective. Cancer Res. 2007;67(19):8985-8988.
-
(2007)
Cancer Res
, vol.67
, Issue.19
, pp. 8985-8988
-
-
Kern, S.E.1
Shibata, D.2
-
44
-
-
0030051051
-
Cellular changes involved in conversion of normal to malignant breast: Importance of the stromal reaction
-
Ronnov-Jessen L, Petersen OW, Bissell MJ. Cellular changes involved in conversion of normal to malignant breast: importance of the stromal reaction. Physiol Rev. 1996;76(1):69-125.
-
(1996)
Physiol Rev
, vol.76
, Issue.1
, pp. 69-125
-
-
Ronnov-Jessen, L.1
Petersen, O.W.2
Bissell, M.J.3
-
45
-
-
77954127287
-
Insights into the cell of origin in breast cancer and breast cancer stem cells
-
Lindeman GJ, Visvader JE. Insights into the cell of origin in breast cancer and breast cancer stem cells. Asia Pac J Clin Oncol. 2010;6(2):89-97.
-
(2010)
Asia Pac J Clin Oncol
, vol.6
, Issue.2
, pp. 89-97
-
-
Lindeman, G.J.1
Visvader, J.E.2
-
46
-
-
57349143739
-
Efficient tumour formation by single human melanoma cells
-
Quintana E, Shackleton M, Sabel MS, Fullen DR, Johnson TM, Morrison SJ. Efficient tumour formation by single human melanoma cells. Nature. 2008;456(7222):593-598.
-
(2008)
Nature
, vol.456
, Issue.7222
, pp. 593-598
-
-
Quintana, E.1
Shackleton, M.2
Sabel, M.S.3
Fullen, D.R.4
Johnson, T.M.5
Morrison, S.J.6
-
47
-
-
58449087260
-
Detection and analysis of mammary gland stem cells
-
Stingl J. Detection and analysis of mammary gland stem cells. J Pathol. 2009;217(2):229-241.
-
(2009)
J Pathol
, vol.217
, Issue.2
, pp. 229-241
-
-
Stingl, J.1
-
48
-
-
77953160885
-
Dynamic regulation of CD24 and the invasive, CD44posCD24neg phenotype in breast cancer cell lines
-
Meyer MJ, Fleming JM, Ali MA, Pesesky MW, Ginsburg E, Vonderhaar BK. Dynamic regulation of CD24 and the invasive, CD44posCD24neg phenotype in breast cancer cell lines. Breast Cancer Res. 2009;11(6):R82.
-
(2009)
Breast Cancer Res
, vol.11
, Issue.6
-
-
Meyer, M.J.1
Fleming, J.M.2
Ali, M.A.3
Pesesky, M.W.4
Ginsburg, E.5
Vonderhaar, B.K.6
-
49
-
-
70349123829
-
The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells
-
Cicalese A, Bonizzi G, Pasi CE, et al. The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells. Cell. 2009;138(6):1083-1095.
-
(2009)
Cell
, vol.138
, Issue.6
, pp. 1083-1095
-
-
Cicalese, A.1
Bonizzi, G.2
Pasi, C.E.3
-
50
-
-
0017167185
-
The clonal evolution of tumor cell populations
-
Nowell PC. The clonal evolution of tumor cell populations. Science. 1976;194(4260):23-28.
-
(1976)
Science
, vol.194
, Issue.4260
, pp. 23-28
-
-
Nowell, P.C.1
-
51
-
-
66249136447
-
Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis
-
Spencer SL, Gaudet S, Albeck JG, Burke JM, Sorger PK. Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis. Nature. 2009;459(7245):428-432.
-
(2009)
Nature
, vol.459
, Issue.7245
, pp. 428-432
-
-
Spencer, S.L.1
Gaudet, S.2
Albeck, J.G.3
Burke, J.M.4
Sorger, P.K.5
-
52
-
-
84860214990
-
Intra-tumour heterogeneity: A looking glass for cancer?
-
Marusyk A, Almendro V, Polyak K. Intra-tumour heterogeneity: a looking glass for cancer? Nat Rev Cancer. 2012;12(5):323-334.
-
(2012)
Nat Rev Cancer
, vol.12
, Issue.5
, pp. 323-334
-
-
Marusyk, A.1
Almendro, V.2
Polyak, K.3
-
53
-
-
75549083303
-
Tumor heterogeneity: Causes and consequences
-
Marusyk A, Polyak K. Tumor heterogeneity: causes and consequences. Biochim Biophys Acta. 2010;1805(1):105-117.
-
(2010)
Biochim Biophys Acta
, vol.1805
, Issue.1
, pp. 105-117
-
-
Marusyk, A.1
Polyak, K.2
-
54
-
-
79953766940
-
Tumour evolution inferred by singlecell sequencing
-
Navin N, Kendall J, Troge J, et al. Tumour evolution inferred by singlecell sequencing. Nature. 2011;472(7341):90-94.
-
(2011)
Nature
, vol.472
, Issue.7341
, pp. 90-94
-
-
Navin, N.1
Kendall, J.2
Troge, J.3
-
55
-
-
84862526929
-
The clonal and mutational evolution spectrum of primary triple-negative breast cancers
-
Shah SP, Roth A, Goya R, et al. The clonal and mutational evolution spectrum of primary triple-negative breast cancers. Nature. 2012; 486(7403):395-399.
-
(2012)
Nature
, vol.486
, Issue.7403
, pp. 395-399
-
-
Shah, S.P.1
Roth, A.2
Goya, R.3
-
56
-
-
84869209828
-
Stem cell plasticity in development and cancer: Epigenetic origin of cancer stem cells
-
Kundu TK, editor, New York: Springer
-
Shah M, Allegrucci C. Stem cell plasticity in development and cancer: epigenetic origin of cancer stem cells. In: Kundu TK, editor. Epigenetics: Development and Disease. Vol 61. New York: Springer; 2012.
-
(2012)
Epigenetics: Development and Disease
, vol.61
-
-
Shah, M.1
Allegrucci, C.2
-
57
-
-
34249897719
-
Restriction landmark genome scanning identifies culture-induced DNA methylation instability in the human embryonic stem cell epigenome
-
Allegrucci C, Wu YZ, Thurston A, et al. Restriction landmark genome scanning identifies culture-induced DNA methylation instability in the human embryonic stem cell epigenome. Hum Mol Genet. 2007;16(10):1253-1268.
-
(2007)
Hum Mol Genet
, vol.16
, Issue.10
, pp. 1253-1268
-
-
Allegrucci, C.1
Wu, Y.Z.2
Thurston, A.3
-
58
-
-
33747879037
-
Abnormal CpG island methylation occurs during in vitro differentiation of human embryonic stem cells
-
Shen Y, Chow J, Wang Z, Fan G. Abnormal CpG island methylation occurs during in vitro differentiation of human embryonic stem cells. Hum Mol Genet. 2006;15(17):2623-2635.
-
(2006)
Hum Mol Genet
, vol.15
, Issue.17
, pp. 2623-2635
-
-
Shen, Y.1
Chow, J.2
Wang, Z.3
Fan, G.4
-
59
-
-
33846576622
-
Epigenetic stem cell signature in cancer
-
Widschwendter M, Fiegl H, Egle D, et al. Epigenetic stem cell signature in cancer. Nat Genet. 2007;39(2):157-158.
-
(2007)
Nat Genet
, vol.39
, Issue.2
, pp. 157-158
-
-
Widschwendter, M.1
Fiegl, H.2
Egle, D.3
-
60
-
-
33846569960
-
A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing
-
Ohm JE, McGarvey KM, Yu X, et al. A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing. Nat Genet. 2007;39(2):237-242.
-
(2007)
Nat Genet
, vol.39
, Issue.2
, pp. 237-242
-
-
Ohm, J.E.1
McGarvey, K.M.2
Yu, X.3
-
61
-
-
33846649587
-
Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer
-
Schlesinger Y, Straussman R, Keshet I, et al. Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer. Nat Genet. 2007;39(2):232-236.
-
(2007)
Nat Genet
, vol.39
, Issue.2
, pp. 232-236
-
-
Schlesinger, Y.1
Straussman, R.2
Keshet, I.3
-
62
-
-
80051967505
-
Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells
-
Gupta PB, Fillmore CM, Jiang G, et al. Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells. Cell. 2011;146(4):633-644.
-
(2011)
Cell
, vol.146
, Issue.4
, pp. 633-644
-
-
Gupta, P.B.1
Fillmore, C.M.2
Jiang, G.3
-
63
-
-
79956351015
-
Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state
-
Chaffer CL, Brueckmann I, Scheel C, et al. Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state. Proc Natl Acad Sci U S A. 2011;108(19):7950-7955.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, Issue.19
, pp. 7950-7955
-
-
Chaffer, C.L.1
Brueckmann, I.2
Scheel, C.3
-
64
-
-
42649112047
-
An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
-
Ben-Porath I, Thomson MW, Carey VJ, et al. An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nat Genet. 2008;40(5):499-507.
-
(2008)
Nat Genet
, vol.40
, Issue.5
, pp. 499-507
-
-
Ben-Porath, I.1
Thomson, M.W.2
Carey, V.J.3
-
65
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
Mani SA, Guo W, Liao MJ, et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell. 2008;133(4): 704-715.
-
(2008)
Cell
, vol.133
, Issue.4
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
-
66
-
-
63049123066
-
Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
-
Polyak K, Weinberg RA. Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat Rev Cancer. 2009;9(4):265-273.
-
(2009)
Nat Rev Cancer
, vol.9
, Issue.4
, pp. 265-273
-
-
Polyak, K.1
Weinberg, R.A.2
-
67
-
-
52949122883
-
Cell type-specific DNA methylation patterns in the human breast
-
Bloushtain-Qimron N, Yao J, Snyder EL, et al. Cell type-specific DNA methylation patterns in the human breast. Proc Natl Acad Sci U S A. 2008;105(37):14076-14081.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.37
, pp. 14076-14081
-
-
Bloushtain-Qimron, N.1
Yao, J.2
Snyder, E.L.3
-
68
-
-
84866423871
-
MicroRNAs in the p53 network: Micromanagement of tumour suppression
-
Hermeking H. MicroRNAs in the p53 network: micromanagement of tumour suppression. Nat Rev Cancer. 2012;12(9):613-626.
-
(2012)
Nat Rev Cancer
, vol.12
, Issue.9
, pp. 613-626
-
-
Hermeking, H.1
-
69
-
-
68049114782
-
Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells
-
Shimono Y, Zabala M, Cho RW, et al. Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells. Cell. 2009;138(3):592-603.
-
(2009)
Cell
, vol.138
, Issue.3
, pp. 592-603
-
-
Shimono, Y.1
Zabala, M.2
Cho, R.W.3
-
70
-
-
78549249141
-
MicroRNAs, cancer and cancer stem cells
-
Zimmerman AL, Wu S. MicroRNAs, cancer and cancer stem cells. Cancer Lett. 2011;300(1):10-19.
-
(2011)
Cancer Lett
, vol.300
, Issue.1
, pp. 10-19
-
-
Zimmerman, A.L.1
Wu, S.2
-
71
-
-
81755186916
-
Jumonji/ARID1 B (JARID1B) protein promotes breast tumor cell cycle progression through epigenetic repression of microRNA let-7e
-
Mitra D, Das PM, Huynh FC, Jones FE. Jumonji/ARID1 B (JARID1B) protein promotes breast tumor cell cycle progression through epigenetic repression of microRNA let-7e. J Biol Chem. 2011;286(47):40531-40535.
-
(2011)
J Biol Chem
, vol.286
, Issue.47
, pp. 40531-40535
-
-
Mitra, D.1
Das, P.M.2
Huynh, F.C.3
Jones, F.E.4
-
72
-
-
34250320926
-
Breast cancer associated transcriptional repressor PLU-1/JARID1B interacts directly with histone deacetylases
-
Barrett A, Santangelo S, Tan K, et al. Breast cancer associated transcriptional repressor PLU-1/JARID1B interacts directly with histone deacetylases. Int J Cancer. 2007;121(2):265-275.
-
(2007)
Int J Cancer
, vol.121
, Issue.2
, pp. 265-275
-
-
Barrett, A.1
Santangelo, S.2
Tan, K.3
-
73
-
-
33646870495
-
Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions
-
Bracken AP, Dietrich N, Pasini D, Hansen KH, Helin K. Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions. Genes Dev. 2006;20(9):1123-1136.
-
(2006)
Genes Dev
, vol.20
, Issue.9
, pp. 1123-1136
-
-
Bracken, A.P.1
Dietrich, N.2
Pasini, D.3
Hansen, K.H.4
Helin, K.5
-
74
-
-
84866050864
-
Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes
-
Holm K, Grabau D, Lovgren K, et al. Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes. Mol Oncol. 2012;6(5):494-506.
-
(2012)
Mol Oncol
, vol.6
, Issue.5
, pp. 494-506
-
-
Holm, K.1
Grabau, D.2
Lovgren, K.3
-
75
-
-
34547566701
-
Transformation of different human breast epithelial cell types leads to distinct tumor phenotypes
-
Ince TA, Richardson AL, Bell GW, et al. Transformation of different human breast epithelial cell types leads to distinct tumor phenotypes. Cancer Cell. 2007;12(2):160-170.
-
(2007)
Cancer Cell
, vol.12
, Issue.2
, pp. 160-170
-
-
Ince, T.A.1
Richardson, A.L.2
Bell, G.W.3
-
76
-
-
69249087671
-
Environment-mediated drug resistance: A major contributor to minimal residual disease
-
Meads MB, Gatenby RA, Dalton WS. Environment-mediated drug resistance: a major contributor to minimal residual disease. Nat Rev Cancer. 2009;9(9):665-674.
-
(2009)
Nat Rev Cancer
, vol.9
, Issue.9
, pp. 665-674
-
-
Meads, M.B.1
Gatenby, R.A.2
Dalton, W.S.3
-
77
-
-
84882869402
-
Breast cancer stem cells: Obstacles to therapy
-
April 30, [Epub ahead of print.]
-
Smalley M, Piggott L, Clarkson R. Breast cancer stem cells: Obstacles to therapy. Cancer Lett. April 30, 2012. [Epub ahead of print.]
-
(2012)
Cancer Lett
-
-
Smalley, M.1
Piggott, L.2
Clarkson, R.3
-
78
-
-
79551600015
-
Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways
-
Takebe N, Harris PJ, Warren RQ, Ivy SP. Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways. Nat Rev Clin Oncol. 2011;8(2):97-106.
-
(2011)
Nat Rev Clin Oncol
, vol.8
, Issue.2
, pp. 97-106
-
-
Takebe, N.1
Harris, P.J.2
Warren, R.Q.3
Ivy, S.P.4
-
79
-
-
70349638289
-
Tumour-initiating cells: Challenges and opportunities for anticancer drug discovery
-
Zhou BB, Zhang H, Damelin M, Geles KG, Grindley JC, Dirks PB. Tumour-initiating cells: challenges and opportunities for anticancer drug discovery. Nat Rev Drug Discov. 2009;8(10):806-823.
-
(2009)
Nat Rev Drug Discov
, vol.8
, Issue.10
, pp. 806-823
-
-
Zhou, B.B.1
Zhang, H.2
Damelin, M.3
Geles, K.G.4
Grindley, J.C.5
Dirks, P.B.6
-
80
-
-
78650035864
-
Cancer stem cells: Problems for therapy?
-
Alison MR, Lim SM, Nicholson LJ. Cancer stem cells: problems for therapy? J Pathol. 2011;223(2):147-161.
-
(2011)
J Pathol
, vol.223
, Issue.2
, pp. 147-161
-
-
Alison, M.R.1
Lim, S.M.2
Nicholson, L.J.3
-
81
-
-
84859949726
-
Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity
-
Kim J, Villadsen R, Sorlie T, et al. Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity. Proc Natl Acad Sci U S A. 2012;109(16):6124-6129.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, Issue.16
, pp. 6124-6129
-
-
Kim, J.1
Villadsen, R.2
Sorlie, T.3
-
82
-
-
84865494894
-
Stem cells in breast tumours: Are they ready for the clinic?
-
Ablett MP, Singh JK, Clarke RB. Stem cells in breast tumours: Are they ready for the clinic? Eur J Cancer. 2012;48(14):2104-2116.
-
(2012)
Eur J Cancer
, vol.48
, Issue.14
, pp. 2104-2116
-
-
Ablett, M.P.1
Singh, J.K.2
Clarke, R.B.3
-
83
-
-
78149478781
-
Aberrant epigenetic landscape in cancer: How cellular identity goes awry
-
Berdasco M, Esteller M. Aberrant epigenetic landscape in cancer: how cellular identity goes awry. Dev Cell. 2010;19(5):698-711.
-
(2010)
Dev Cell
, vol.19
, Issue.5
, pp. 698-711
-
-
Berdasco, M.1
Esteller, M.2
-
84
-
-
78651280899
-
Epigenetic reprogramming of breast cancer cells with oocyte extracts
-
Allegrucci C, Rushton MD, Dixon JE, et al. Epigenetic reprogramming of breast cancer cells with oocyte extracts. Mol Cancer. 2011; 10(1):7.
-
(2011)
Mol Cancer
, vol.10
, Issue.1
, pp. 7
-
-
Allegrucci, C.1
Rushton, M.D.2
Dixon, J.E.3
-
85
-
-
77953365022
-
Decitabine maintains hematopoietic precursor self-renewal by preventing repression of stem cell genes by a differentiation-inducing stimulus
-
Hu Z, Negrotto S, Gu X, et al. Decitabine maintains hematopoietic precursor self-renewal by preventing repression of stem cell genes by a differentiation-inducing stimulus. Mol Cancer Ther. 2010;9(6): 1536-1543.
-
(2010)
Mol Cancer Ther
, vol.9
, Issue.6
, pp. 1536-1543
-
-
Hu, Z.1
Negrotto, S.2
Gu, X.3
-
86
-
-
84863337757
-
Transient low doses of DNA- demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells
-
Tsai HC, Li H, Van Neste L, et al. Transient low doses of DNA- demethylating agents exert durable antitumor effects on hematological and epithelial tumor cells. Cancer Cell. 2012;21(3):430-446.
-
(2012)
Cancer Cell
, vol.21
, Issue.3
, pp. 430-446
-
-
Tsai, H.C.1
Li, H.2
van Neste, L.3
|