Age-related loss of nitric oxide synthase in skeletal muscle causes reductions in calpain S-nitrosylation that increase myofibril degradation and sarcopenia

Aging Cell

Volumn 11, Issue 6, 2012, Pages 1036-1045

  Samengo, Giuseppina ^a   Avik, Anna ^a   Fedor, Brian ^a   Whittaker, Daniel ^a   Myung, Kyu H ^b   Wehling Henricks, Michelle ^a   Tidball, James G ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Chonnam National University   (South Korea)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Aging; Calpain; Nitric oxide; Sarcopenia; Skeletal muscle

Indexed keywords

CALPAIN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; MOUSE; MUSCLE ATROPHY; MUSCLE FIBRIL; NITROSYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN MODIFICATION; SKELETAL MUSCLE;

AGING; ANIMALS; CALCIUM-BINDING PROTEINS; CALPAIN; GENE EXPRESSION; HUMANS; MICE; MUSCLE, SKELETAL; MYOFIBRILS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE I; PROTEIN ISOFORMS; PROTEOLYSIS; SARCOPENIA;

EID: 84869152162     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12003     Document Type: Article

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