Association of lower habitual physical activity level with mitochondrial and endothelial dysfunction in patients with stable coronary artery disease

Circulation Journal

Volumn 76, Issue 11, 2012, Pages 2572-2578

  Luk, Ting Hin ^a   Dai, Yuk Ling ^a   Siu, Chung Wah ^a,b   Yiu, Kai Hang ^a   Li, Sheung Wai ^c   Fong, Bonnie ^d   Wong, Wai Keung ^d   Tam, Sidney ^d   Tse, Hung Fat ^a,b  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

^c TUNG WAH HOSPITAL   (Hong Kong)

^d QUEEN MARY HOSPITAL   (Hong Kong)

Author keywords

Coronary artery disease; Endothelial function; Lactate pyruvate ratio; Physical activity

Indexed keywords

C REACTIVE PROTEIN; CREATININE; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LACTIC ACID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PYRUVIC ACID; TRIACYLGLYCEROL;

AGED; ARTERY BLOOD FLOW; ARTERY DILATATION; ARTICLE; BRACHIAL ARTERY; CARDIOVASCULAR RISK; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CROSS-SECTIONAL STUDY; DISEASE ASSOCIATION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENDOTHELIAL DYSFUNCTION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; PHYSICAL ACTIVITY; PHYSICAL CAPACITY; QUESTIONNAIRE; VASCULAR ENDOTHELIUM;

EID: 84869102095     PISSN: 13469843     EISSN: 13474820     Source Type: Journal    
DOI: 10.1253/circj.CJ-12-0364     Document Type: Article

References (35)

1. Jolliffe JA, Rees K, Taylor RS, Thompson D, Oldridge N, Ebrahim S. Exercise-based rehabilitation for coronary heart disease. Cochrane Database Syst Rev 2001; 1: CD001800.
2. Shibata Y, Hayasaka S, Yamada T, Ojima T, Ishikawa S, Kayaba K, et al; JMS Cohort Study Group. Physical activity and risk of fatal or non-fatal cardiovascular disease among CVD survivors: The JMS cohort study. Circ J 2011; 75: 1368-1372.
3. Chan SY, Mancini GBJ, Kuramoto L, Schulzer M, Frohlich J, Ignaszewski A. The prognostic importance of endothelial dysfunction and carotid atheromaburden in patients with coronary artery disease. J Am Coll Cardiol 2003; 42: 1037-1043.
4. Hosokawa S, Hiasa Y, Takahashi T, Itoh S. Effect of regular exercise on coronary endothelial function in patients with recent myocardial infarction. Circ J 2003; 67: 221-224.
5. Lim S, Despres JP, Koh KK. Prevention of atherosclerosis in overweight/ obese patients: In need of novel multi-targeted approaches. Circ J 2011; 75: 1019-1027.
6. Luk TH, Dai YL, Siu CW, Yiu KH, Chan HT, Fong DY, et al. Habitual physical activity is associated with endothelial function and endothelial progenitor cells in patients with stable coronary artery disease. Eur J Cardiovasc Prev Rehabil 2009; 16: 464-471.
7. Knight-Lozano CA, Young CG, Burow DL, Hu ZY, Uyeminami D, Pinkerton KE, et al. Cigarette smoke exposure and hypercholesterolemia increase mitochondrial damage in cardiovascular tissues. Circulation 2002; 105: 849-854.
8. Kelley DE, He J, Menshikova EV, Ritov VB. Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Diabetes 2002; 51: 2944-2950.
9. Puddu P, Puddu GM, Galletti L, Cravero E, Muscari A. Mitochondrial dysfunction as an initiating event in atherogenesis: A plausible hypothesis. Cardiology 2005; 103: 137-141.
10. Madamanchi NR, Runge MS. Mitochondrial dysfunction in atherosclerosis. Circ Res 2007; 100: 460-473.
11. Ballinger SW, Patterson C, Yan CN, Doan R, Burow DL, Young CG, et al. Hydrogen peroxide-and peroxynitrite-induced mitochondrial DNA damage and dysfunction in vascular endothelial and smooth muscle cells. Circ Res 2000; 86: 960-966.
12. Wenzel P, Schuhmacher S, Kienhofer J, Muller J, Hortmann M, Oelze M, et al. Manganese superoxide dismutase and aldehyde dehydrogenase deficiency increase mitochondrial oxidative stress and aggravate age-dependent vascular dysfunction. Cardiovasc Res 2008; 80: 280-289.
13. Dai YL, Luk TH, Siu CW, Yiu KH, Chan HT, Lee SW, et al. Mitochondrial dysfunction induced by statin contributes to endothelial dysfunction in patients with coronary artery disease. Cardiovasc Toxicol 2010; 10: 130-138.
14. De Pinieux G, Chariot P, Ammi-Said M, Louarn F, Lejonc JL, Astier A, et al. Lipid-lowering drugs and mitochondrial function: Effects of HMG-CoA reductase inhibitors on serum ubiquinone and blood lactate/ pyruvate ratio. Br J Clin Pharmacol 1996; 42: 333-337.
15. Jubrias SA, Esselman PC, Price LB, Cress ME, Conley KE. Large energetic adaptations of elderly muscle to resistance and endurance training. J Appl Physiol 2001; 90: 1663-1670.
16. Short KR, Vittone JL, Bigelow ML, Proctor DN, Rizza RA, Coenen-Schimke JM, et al. Impact of aerobic exercise training on age-related changes in insulin sensitivity and muscle oxidative capacity. Diabetes 2003; 52: 1888-1896.
17. Menshikova EV, Ritov VB, Fairfull L, Ferrell RE, Kelley DE, Goodpaster BH. Effects of exercise on mitochondrial content and function in aging human skeletal muscle. J Gerontol A Biol Sci Med Sci 2006; 61: 534-540.
18. Lau KK, Chan YH, Yiu KH, Li SW, Tam S, Lau CP, et al. Burden of carotid atherosclerosis in patients with stroke: Relationships with circulating endothelial progenitor cells and hypertension. J Hum Hypertens 2007; 21: 445-451.
19. Tan KC, Wat NM, Tam SC, Janus ED, Lam TH, Lam KS. C-reactive protein predicts the deterioration of glycemia in Chinese subjects with impaired glucose tolerance. Diabetes Care 2003; 26: 2323-2328.
20. Debray FG, Mitchell GA, Allard P, Robinson BH, Hanley JA, Lambert M. Diagnostic accuracy of blood lactate-to-pyruvate molar ratio in the differential diagnosis of congenital lactic acidosis. Clin Chem 2007; 53: 916-921.
21. Craig CL, Marshall AL, Sjostrom M, Bauman AE, Booth ML, Ainsworth BE, et al. International physical activity questionnaire: 12-country reliability and validity. Med Sci Sports Exerc 2003; 35: 1381-1395.
22. Macfarlane DJ, Lee CC, Ho EY, Chan KL, Chan DT. Reliability and validity of the Chinese version of IPAQ (short, last 7 days). J Sci Med Sport 2007; 10: 45-51.
23. Deng HB, Macfarlane DJ, Thomas GN, Lao XQ, Jiang CQ, Cheng KK, et al. Reliability and validity of the IPAQ-Chinese: The Guangzhou Biobank Cohort study. Med Sci Sports Exerc 2008; 40: 303-307.
24. Ip MS, Tse HF, Lam B, Tsang KW, Lam WK. Endothelial function in obstructive sleep apnea and response to treatment. Am J Respir Crit Care Med 2004; 169: 348-353.
25. Higashi Y, Noma K, Yoshizumi M, Kihara Y. Endothelial function and oxidative stress in cardiovascular diseases. Circ J 2009; 73: 411-418.
26. Taddei S, Galetta F, Virdis A, Ghiadoni L, Salvetti G, Franzoni F, et al. Physical activity prevents age-related impairment in nitric oxide availability in elderly athletes. Circulation 2000; 101: 2896-2901.
27. DeSouza CA, Shapiro LF, Clevenger CM, Dinenno FA, Monahan KD, Tanaka H, et al. Regular aerobic exercise prevents and restores age-related declines in endothelium-dependent vasodilation in healthy men. Circulation 2000; 102: 1351-1357.
28. Edwards DG, Schofield RS, Lennon SL, Pierce GL, Nichols WW, Braith RW. Effect of exercise training on endothelial function in men with coronary artery disease. Am J Cardiol 2004; 93: 617-620.
29. Short KR, Bigelow ML, Kahl J, Singh R, Coenen-Schimke J, Raghavakaimal S, et al. Decline in skeletal muscle mitochondrial function with aging in humans. Proc Natl Acad Sci USA 2005; 102: 5618-5623.
30. Toledo FG, Menshikova EV, Ritov VB, Azuma K, Radikova Z, DeLany J, et al. Effects of physical activity and weight loss on skeletal muscle mitochondria and relationship with glucose control in type 2 diabetes. Diabetes 2007; 56: 2142-2147.
31. Menshikova EV, Ritov VB, Ferrell RE, Azuma K, Goodpaster BH, Kelley DE. Characteristics of skeletal muscle mitochondrial biogenesis induced by moderate-intensity exercise and weight loss in obesity. J Appl Physiol 2007; 103: 21-27.
32. Ventura-Clapier R, Mettauer B, Bigard X. Beneficial effects of endurance training on cardiac and skeletal muscle energy metabolism in heart failure. Cardiovasc Res 2007; 73: 10-18.
33. Kojda G, Hambrecht R. Molecular mechanisms of vascular adaptations to exercise: Physical activity as an effective antioxidant therapy? Cardiovasc Res 2005; 67: 187-197.
34. Ascensao A, Ferreira R, Magalhaes J. Exercise-induced cardioprotection--biochemical, morphological and functional evidence in whole tissue and isolated mitochondria. Int J Cardiol 2007; 117: 16-30.
35. Tanasescu M, Leitzmann MF, Rimm EB, Willett WC, Stampfer MJ, Hu FB. Exercise type and intensity in relation to coronary heart disease in men. JAMA 2002; 288: 1994-2000.