Preclinical evaluation of reconsolidation blockade by clonidine as a potential novel treatment for posttraumatic stress disorder

Neuropsychopharmacology

Volumn 37, Issue 13, 2012, Pages 2789-2796

  Gamache, Karine ^a   Pitman, Roger K ^b   Nader, Karim ^a  

^a MCGILL UNIVERSITY   (Canada)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

2 adrenoreceptor agonist; clonidine; fear conditioning; memory; posttraumatic stress disorder; reconsolidation

Indexed keywords

CLONIDINE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONDITIONING; CONTROLLED STUDY; DISEASE MODEL; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFICACY; FEAR; FEMALE; LEARNING; MALE; MEMORY CONSOLIDATION; MEMORY DISORDER; MEMORY RECONSOLIDATION; NONHUMAN; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; PSYCHOPHARMACOTHERAPY; RAT; SHORT TERM MEMORY;

ACOUSTIC STIMULATION; ADRENERGIC ALPHA-2 RECEPTOR AGONISTS; ANIMALS; CLONIDINE; CONDITIONING (PSYCHOLOGY); DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; FEAR; FEMALE; MALE; RATS; RATS, SPRAGUE-DAWLEY; STRESS DISORDERS, POST-TRAUMATIC; TREATMENT OUTCOME;

EID: 84869092559     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2012.145     Document Type: Article

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