Purifying selection modulates the estimates of population differentiation and confounds genome-wide comparisons across single-nucleotide polymorphisms

Molecular Biology and Evolution

Volumn 29, Issue 12, 2012, Pages 3617-3623

  Maruki, Takahiro ^a,b   Kumar, Sudhir ^a,b   Kim, Yuseob ^a,b,c  

^a ARIZONA STATE UNIVERSITY   (United States)

^b ARIZONA STATE UNIVERSITY   (United States)

^c Ewha Womans University   (South Korea)

Author keywords

evolutionary rate; FST; minor allele frequency; population differentiation; purifying selection

Indexed keywords

COMPUTER SIMULATION; CONFERENCE PAPER; GENE FREQUENCY; GENE LOCUS; GENETIC ANALYSIS; HETEROZYGOSITY; MITOCHONDRIAL GENOME; MOLECULAR EVOLUTION; POPULATION DIFFERENTIATION; PURIFYING SELECTION; SINGLE NUCLEOTIDE POLYMORPHISM;

COMPUTER SIMULATION; GENE FREQUENCY; GENETIC LOCI; GENETICS, POPULATION; HUMANS; MODELS, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; SELECTION, GENETIC;

EID: 84869051880     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/mss187     Document Type: Conference Paper

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