메뉴 건너뛰기




Volumn 6, Issue 10, 2012, Pages

Cytokine Responses to Novel Antigens in an Indian Population Living in an Area Endemic for Visceral Leishmaniasis

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; LEISHMANIA HOMOLOG OF RECEPTOR FOR ACTIVATED C KINASE; PARASITE ANTIGEN; PARASITE ANTIGEN J41; PARASITE ANTIGEN J89; PARASITE ANTIGEN L302.06; PARASITE ANTIGEN L37; PARASITE ANTIGEN M18; PARASITE ANTIGEN M22; PARASITE ANTIGEN M57; PARASITE ANTIGEN M63; PARASITE ANTIGEN N52; PARASITE ANTIGEN Q51; PARASITE ANTIGEN R71; PROTEIN KINASE C; TRYPAREDOXIN PEROXIDASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84869014509     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0001874     Document Type: Article
Times cited : (54)

References (49)
  • 1
    • 84861665791 scopus 로고    scopus 로고
    • Leishmaniasis worldwide and global estimates of its incidence
    • Alvar J, Velez ID, Bern C, Herrero M, Desjeux P, et al. (2012) Leishmaniasis worldwide and global estimates of its incidence. PLoS ONE 7: e35671.
    • (2012) PLoS ONE , vol.7
    • Alvar, J.1    Velez, I.D.2    Bern, C.3    Herrero, M.4    Desjeux, P.5
  • 2
    • 0023000883 scopus 로고
    • New perspectives on a subclinical form of visceral leishmaniasis
    • Badaro R, Jones TC, Carvalho EM, Sampaio D, Reed SG, et al. (1986) New perspectives on a subclinical form of visceral leishmaniasis. J Infect Dis 154: 1003-1009.
    • (1986) J Infect Dis , vol.154 , pp. 1003-1009
    • Badaro, R.1    Jones, T.C.2    Carvalho, E.M.3    Sampaio, D.4    Reed, S.G.5
  • 3
    • 0022447028 scopus 로고
    • A prospective study of visceral leishmaniasis in an endemic area of Brazil
    • Badaro R, Jones TC, Lorenco R, Cerf BJ, Sampaio D, et al. (1986) A prospective study of visceral leishmaniasis in an endemic area of Brazil. J Infect Dis 154: 639-649.
    • (1986) J Infect Dis , vol.154 , pp. 639-649
    • Badaro, R.1    Jones, T.C.2    Lorenco, R.3    Cerf, B.J.4    Sampaio, D.5
  • 5
    • 0346217977 scopus 로고    scopus 로고
    • Natural history of Leishmania (Leishmania) chagasi infection in Northeastern Brazil: long-term follow-up
    • Jeronimo SM, Teixeira MJ, Sousa A, Thielking P, Pearson RD, et al. (2000) Natural history of Leishmania (Leishmania) chagasi infection in Northeastern Brazil: long-term follow-up. Clin Infect Dis 30: 608-609.
    • (2000) Clin Infect Dis , vol.30 , pp. 608-609
    • Jeronimo, S.M.1    Teixeira, M.J.2    Sousa, A.3    Thielking, P.4    Pearson, R.D.5
  • 6
    • 79955836896 scopus 로고    scopus 로고
    • Interferon-gamma release assay (modified Quantiferon) as a potential marker of infection for Leishmania donovani, a proof of concept study
    • Gidwani K, Jones S, Kumar R, Boelaert M, Sundar S, (2011) Interferon-gamma release assay (modified Quantiferon) as a potential marker of infection for Leishmania donovani, a proof of concept study. PLoS Negl Trop Dis 5: e1042.
    • (2011) PLoS Negl Trop Dis , vol.5
    • Gidwani, K.1    Jones, S.2    Kumar, R.3    Boelaert, M.4    Sundar, S.5
  • 7
    • 80055078978 scopus 로고    scopus 로고
    • Incidence of symptomatic and asymptomatic Leishmania donovani infections in high-endemic foci in India and Nepal: a prospective study
    • Ostyn B, Gidwani K, Khanal B, Picado A, Chappuis F, et al. (2011) Incidence of symptomatic and asymptomatic Leishmania donovani infections in high-endemic foci in India and Nepal: a prospective study. PLoS Negl Trop Dis 5: e1284.
    • (2011) PLoS Negl Trop Dis , vol.5
    • Ostyn, B.1    Gidwani, K.2    Khanal, B.3    Picado, A.4    Chappuis, F.5
  • 8
    • 34347218231 scopus 로고    scopus 로고
    • The epidemiology of visceral leishmaniasis and asymptomatic leishmanial infection in a highly endemic Bangladeshi village
    • Bern C, Haque R, Chowdhury R, Ali M, Kurkjian KM, et al. (2007) The epidemiology of visceral leishmaniasis and asymptomatic leishmanial infection in a highly endemic Bangladeshi village. Am J Trop Med Hyg 76: 909-914.
    • (2007) Am J Trop Med Hyg , vol.76 , pp. 909-914
    • Bern, C.1    Haque, R.2    Chowdhury, R.3    Ali, M.4    Kurkjian, K.M.5
  • 9
    • 75649091127 scopus 로고    scopus 로고
    • Why does immunity to parasites take so long to develop?
    • Yazdanbakhsh M, Sacks DL, (2010) Why does immunity to parasites take so long to develop? Nat Rev Immunol 10: 80-81.
    • (2010) Nat Rev Immunol , vol.10 , pp. 80-81
    • Yazdanbakhsh, M.1    Sacks, D.L.2
  • 10
    • 34548543615 scopus 로고    scopus 로고
    • Interleukin-10 and the pathogenesis of human visceral leishmaniasis
    • Nylen S, Sacks D, (2007) Interleukin-10 and the pathogenesis of human visceral leishmaniasis. Trends Immunol 28: 378-384.
    • (2007) Trends Immunol , vol.28 , pp. 378-384
    • Nylen, S.1    Sacks, D.2
  • 11
    • 34250303350 scopus 로고    scopus 로고
    • Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major
    • Darrah PA, Patel DT, De Luca PM, Lindsay RW, Davey DF, et al. (2007) Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major. Nat Med 13: 843-850.
    • (2007) Nat Med , vol.13 , pp. 843-850
    • Darrah, P.A.1    Patel, D.T.2    de Luca, P.M.3    Lindsay, R.W.4    Davey, D.F.5
  • 12
    • 23444440849 scopus 로고    scopus 로고
    • IL-10 from regulatory T cells determines vaccine efficacy in murine Leishmania major infection
    • Stober C, Lange U, Roberts MTM, Alcami A, Blackwell JM, (2005) IL-10 from regulatory T cells determines vaccine efficacy in murine Leishmania major infection. J Immunol 175: 2517-2514.
    • (2005) J Immunol , vol.175 , pp. 2514-2517
    • Stober, C.1    Lange, U.2    Roberts, M.T.M.3    Alcami, A.4    Blackwell, J.M.5
  • 13
    • 43649094153 scopus 로고    scopus 로고
    • Intradermal NKT cell activation during DNA priming in heterologous prime-boost vaccination enhances T cell responses and protection against Leishmania
    • Dondji B, Deak E, Goldsmith-Pestana K, Perez-Jimenez E, Esteban M, et al. (2008) Intradermal NKT cell activation during DNA priming in heterologous prime-boost vaccination enhances T cell responses and protection against Leishmania. Eur J Immunol 38: 706-719.
    • (2008) Eur J Immunol , vol.38 , pp. 706-719
    • Dondji, B.1    Deak, E.2    Goldsmith-Pestana, K.3    Perez-Jimenez, E.4    Esteban, M.5
  • 14
    • 11144353591 scopus 로고    scopus 로고
    • A CD4(+) T-cell immune response to a conserved epitope in the circumsporozoite protein correlates with protection from natural Plasmodium falciparum infection and disease
    • Reece WH, Pinder M, Gothard PK, Milligan P, Bojang K, et al. (2004) A CD4(+) T-cell immune response to a conserved epitope in the circumsporozoite protein correlates with protection from natural Plasmodium falciparum infection and disease. Nat Med 10: 406-410.
    • (2004) Nat Med , vol.10 , pp. 406-410
    • Reece, W.H.1    Pinder, M.2    Gothard, P.K.3    Milligan, P.4    Bojang, K.5
  • 15
    • 0035433812 scopus 로고    scopus 로고
    • Successful use of a defined antigen/GM-CSF adjuvant vaccine to treat mucosal Leishmaniasis refractory to antimony: A case report
    • Badaro R, Lobo I, Nakatani M, Muinos A, Netto EM, et al. (2001) Successful use of a defined antigen/GM-CSF adjuvant vaccine to treat mucosal Leishmaniasis refractory to antimony: A case report. Braz J Infect Dis 5: 223-232.
    • (2001) Braz J Infect Dis , vol.5 , pp. 223-232
    • Badaro, R.1    Lobo, I.2    Nakatani, M.3    Muinos, A.4    Netto, E.M.5
  • 16
    • 0034605714 scopus 로고    scopus 로고
    • Autoclaved Leishmania major vaccine for prevention of visceral leishmaniasis: a randomised, double-blind, BCG-controlled trial in Sudan
    • Khalil EA, El Hassan AM, Zijlstra EE, Mukhtar MM, Ghalib HW, et al. (2000) Autoclaved Leishmania major vaccine for prevention of visceral leishmaniasis: a randomised, double-blind, BCG-controlled trial in Sudan. Lancet 356: 1565-1569.
    • (2000) Lancet , vol.356 , pp. 1565-1569
    • Khalil, E.A.1    El Hassan, A.M.2    Zijlstra, E.E.3    Mukhtar, M.M.4    Ghalib, H.W.5
  • 17
    • 67650506229 scopus 로고    scopus 로고
    • Efficacy of killed whole-parasite vaccines in the prevention of leishmaniasis: a meta-analysis
    • Noazin S, Khamesipour A, Moulton LH, Tanner M, Nasseri K, et al. (2009) Efficacy of killed whole-parasite vaccines in the prevention of leishmaniasis: a meta-analysis. Vaccine 27: 4747-4753.
    • (2009) Vaccine , vol.27 , pp. 4747-4753
    • Noazin, S.1    Khamesipour, A.2    Moulton, L.H.3    Tanner, M.4    Nasseri, K.5
  • 18
    • 0022852275 scopus 로고
    • Controlled field trials of a vaccine against New World cutaneous leishmaniasis
    • Antunes CM, Mayrink W, Magalhaes PA, Costa CA, Melo MN, et al. (1986) Controlled field trials of a vaccine against New World cutaneous leishmaniasis. Int J Epidemiol 15: 572-580.
    • (1986) Int J Epidemiol , vol.15 , pp. 572-580
    • Antunes, C.M.1    Mayrink, W.2    Magalhaes, P.A.3    Costa, C.A.4    Melo, M.N.5
  • 19
    • 0034605714 scopus 로고    scopus 로고
    • Autoclaved Leishmania major vaccine for prevention of visceral leishmaniasis: a randomised, double-blind, BCG-controlled trial in Sudan
    • Khalil EA, El Hassan AM, Zijlstra EE, Mukhtar MM, Ghalib HW, et al. (2000) Autoclaved Leishmania major vaccine for prevention of visceral leishmaniasis: a randomised, double-blind, BCG-controlled trial in Sudan. Lancet 356: 1565-1569.
    • (2000) Lancet , vol.356 , pp. 1565-1569
    • Khalil, E.A.1    El Hassan, A.M.2    Zijlstra, E.E.3    Mukhtar, M.M.4    Ghalib, H.W.5
  • 21
    • 0033524709 scopus 로고    scopus 로고
    • A randomised, double-blind, controlled trial of a killed L. major vaccine plus BCG against zoonotic cutaneous leishmaniasis in Iran
    • Momeni AZ, Jalayer T, Emamjomeh M, Khamesipour A, Zicker F, et al. (1999) A randomised, double-blind, controlled trial of a killed L. major vaccine plus BCG against zoonotic cutaneous leishmaniasis in Iran. Vaccine 17: 466-472.
    • (1999) Vaccine , vol.17 , pp. 466-472
    • Momeni, A.Z.1    Jalayer, T.2    Emamjomeh, M.3    Khamesipour, A.4    Zicker, F.5
  • 22
    • 7144254432 scopus 로고    scopus 로고
    • Randomised vaccine trial of single dose of killed Leishmania major plus BCG against anthroponotic cutaneous leishmaniasis in Bam, Iran
    • Sharifi I, FeKri AR, Aflatonian MR, Khamesipour A, Nadim A, et al. (1998) Randomised vaccine trial of single dose of killed Leishmania major plus BCG against anthroponotic cutaneous leishmaniasis in Bam, Iran. Lancet 351: 1540-1543.
    • (1998) Lancet , vol.351 , pp. 1540-1543
    • Sharifi, I.1    FeKri, A.R.2    Aflatonian, M.R.3    Khamesipour, A.4    Nadim, A.5
  • 23
    • 84861743216 scopus 로고    scopus 로고
    • Reassessment of immune correlates in human visceral leishmaniasis as defined by cytokine release in whole blood
    • Singh OP, Gidwani K, Kumar R, Nylen S, Jones SL, et al. (2012) Reassessment of immune correlates in human visceral leishmaniasis as defined by cytokine release in whole blood. Clin Vaccine Immunol 19: 961-966.
    • (2012) Clin Vaccine Immunol , vol.19 , pp. 961-966
    • Singh, O.P.1    Gidwani, K.2    Kumar, R.3    Nylen, S.4    Jones, S.L.5
  • 25
    • 33344470954 scopus 로고    scopus 로고
    • From genome to vaccines for leishmaniasis: screening 100 novel vaccine candidates against murine Leishmania major infection
    • Stober CB, Lange UG, Roberts MT, Gilmartin B, Francis R, et al. (2006) From genome to vaccines for leishmaniasis: screening 100 novel vaccine candidates against murine Leishmania major infection. Vaccine 24: 2602-2616.
    • (2006) Vaccine , vol.24 , pp. 2602-2616
    • Stober, C.B.1    Lange, U.G.2    Roberts, M.T.3    Gilmartin, B.4    Francis, R.5
  • 26
    • 0023265277 scopus 로고
    • Vaccination against cutaneous leishmaniasis in a murine model. II. Immunologic properties of protective and nonprotective subfractions of soluble promastigote extract
    • Scott P, Pearce E, Natovitz P, Sher A, (1987) Vaccination against cutaneous leishmaniasis in a murine model. II. Immunologic properties of protective and nonprotective subfractions of soluble promastigote extract. J Immunol 139: 3118-3125.
    • (1987) J Immunol , vol.139 , pp. 3118-3125
    • Scott, P.1    Pearce, E.2    Natovitz, P.3    Sher, A.4
  • 28
    • 84867918677 scopus 로고    scopus 로고
    • Cytokine responses to novel antigens in a peri-urban population in Brazil exposed to Leishmania infantum chagasi
    • Stober CB, Jeronimo SMB, Pontes NN, Miller EN, Blackwell JM, (2012) Cytokine responses to novel antigens in a peri-urban population in Brazil exposed to Leishmania infantum chagasi. Am J Trop Med Hyg in press.
    • (2012) Am J Trop Med Hyg
    • Stober, C.B.1    Jeronimo, S.M.B.2    Pontes, N.N.3    Miller, E.N.4    Blackwell, J.M.5
  • 30
    • 34247350697 scopus 로고    scopus 로고
    • Splenic accumulation of IL-10 mRNA in T cells distinct from CD4+CD25+ (Foxp3) regulatory T cells in human visceral leishmaniasis
    • Nylen S, Maurya R, Eidsmo L, Manandhar KD, Sundar S, et al. (2007) Splenic accumulation of IL-10 mRNA in T cells distinct from CD4+CD25+ (Foxp3) regulatory T cells in human visceral leishmaniasis. J Exp Med 204: 805-817.
    • (2007) J Exp Med , vol.204 , pp. 805-817
    • Nylen, S.1    Maurya, R.2    Eidsmo, L.3    Manandhar, K.D.4    Sundar, S.5
  • 31
    • 33846797935 scopus 로고    scopus 로고
    • Heterologous priming-boosting with DNA and modified vaccinia virus Ankara expressing tryparedoxin peroxidase promotes long-term memory against Leishmania major in susceptible BALB/c Mice
    • Stober CB, Lange UG, Roberts MT, Alcami A, Blackwell JM, (2007) Heterologous priming-boosting with DNA and modified vaccinia virus Ankara expressing tryparedoxin peroxidase promotes long-term memory against Leishmania major in susceptible BALB/c Mice. Infect Immun 75: 852-860.
    • (2007) Infect Immun , vol.75 , pp. 852-860
    • Stober, C.B.1    Lange, U.G.2    Roberts, M.T.3    Alcami, A.4    Blackwell, J.M.5
  • 32
    • 21044441505 scopus 로고    scopus 로고
    • Protective vaccination against experimental canine visceral leishmaniasis using a combination of DNA and protein immunization with cysteine proteinases type I and II of L. infantum
    • Rafati S, Nakhaee A, Taheri T, Taslimi Y, Darabi H, et al. (2005) Protective vaccination against experimental canine visceral leishmaniasis using a combination of DNA and protein immunization with cysteine proteinases type I and II of L. infantum. Vaccine 23: 3716-3725.
    • (2005) Vaccine , vol.23 , pp. 3716-3725
    • Rafati, S.1    Nakhaee, A.2    Taheri, T.3    Taslimi, Y.4    Darabi, H.5
  • 33
    • 68949108180 scopus 로고    scopus 로고
    • Immunization with the DNA-encoding N-terminal domain of proteophosphoglycan of Leishmania donovani generates Th1-type immunoprotective response against experimental visceral leishmaniasis
    • Samant M, Gupta R, Kumari S, Misra P, Khare P, et al. (2009) Immunization with the DNA-encoding N-terminal domain of proteophosphoglycan of Leishmania donovani generates Th1-type immunoprotective response against experimental visceral leishmaniasis. J Immunol 183: 470-479.
    • (2009) J Immunol , vol.183 , pp. 470-479
    • Samant, M.1    Gupta, R.2    Kumari, S.3    Misra, P.4    Khare, P.5
  • 34
    • 20444402610 scopus 로고    scopus 로고
    • A heterologous prime-boost vaccination regimen using ORFF DNA and recombinant ORFF protein confers protective immunity against experimental visceral leishmaniasis
    • Tewary P, Jain M, Sahani MH, Saxena S, Madhubala R, (2005) A heterologous prime-boost vaccination regimen using ORFF DNA and recombinant ORFF protein confers protective immunity against experimental visceral leishmaniasis. J Infect Dis 191: 2130-2137.
    • (2005) J Infect Dis , vol.191 , pp. 2130-2137
    • Tewary, P.1    Jain, M.2    Sahani, M.H.3    Saxena, S.4    Madhubala, R.5
  • 35
    • 84355162776 scopus 로고    scopus 로고
    • The development and clinical evaluation of second-generation leishmaniasis vaccines
    • Duthie MS, Raman VS, Piazza FM, Reed SG, (2012) The development and clinical evaluation of second-generation leishmaniasis vaccines. Vaccine 30: 134-141.
    • (2012) Vaccine , vol.30 , pp. 134-141
    • Duthie, M.S.1    Raman, V.S.2    Piazza, F.M.3    Reed, S.G.4
  • 36
    • 79955028631 scopus 로고    scopus 로고
    • A clinical trial to evaluate the safety and immunogenicity of the LEISH-F1+MPL-SE vaccine for use in the prevention of visceral leishmaniasis
    • Chakravarty J, Kumar S, Trivedi S, Rai VK, Singh A, et al. (2011) A clinical trial to evaluate the safety and immunogenicity of the LEISH-F1+MPL-SE vaccine for use in the prevention of visceral leishmaniasis. Vaccine 29: 3531-3537.
    • (2011) Vaccine , vol.29 , pp. 3531-3537
    • Chakravarty, J.1    Kumar, S.2    Trivedi, S.3    Rai, V.K.4    Singh, A.5
  • 37
    • 0035426014 scopus 로고    scopus 로고
    • Patterns and implications of naturally acquired immune responses to environmental and tuberculous mycobacterial antigens in northern Malawi
    • Black GF, Dockrell HM, Crampin AC, Floyd S, Weir RE, et al. (2001) Patterns and implications of naturally acquired immune responses to environmental and tuberculous mycobacterial antigens in northern Malawi. J Infect Dis 184: 322-329.
    • (2001) J Infect Dis , vol.184 , pp. 322-329
    • Black, G.F.1    Dockrell, H.M.2    Crampin, A.C.3    Floyd, S.4    Weir, R.E.5
  • 38
    • 0034944872 scopus 로고    scopus 로고
    • Relationship between IFN-gamma and skin test responsiveness to Mycobacterium tuberculosis PPD in healthy, non-BCG-vaccinated young adults in Northern Malawi
    • Black GF, Fine PEM, Warndorff DK, Floyd S, Weir RE, et al. (2001) Relationship between IFN-gamma and skin test responsiveness to Mycobacterium tuberculosis PPD in healthy, non-BCG-vaccinated young adults in Northern Malawi. Int J Tuberc Lung Dis 5: 664-672.
    • (2001) Int J Tuberc Lung Dis , vol.5 , pp. 664-672
    • Black, G.F.1    Fine, P.E.M.2    Warndorff, D.K.3    Floyd, S.4    Weir, R.E.5
  • 39
    • 0037140178 scopus 로고    scopus 로고
    • BCG-induced increase in interferon-gamma response to mycobacterial antigens and efficacy of BCG vaccination in Malawi and the UK: two randomised controlled studies
    • Black GF, Weir RE, Floyd S, Bliss L, Warndorff DK, et al. (2002) BCG-induced increase in interferon-gamma response to mycobacterial antigens and efficacy of BCG vaccination in Malawi and the UK: two randomised controlled studies. Lancet 359: 1393-1401.
    • (2002) Lancet , vol.359 , pp. 1393-1401
    • Black, G.F.1    Weir, R.E.2    Floyd, S.3    Bliss, L.4    Warndorff, D.K.5
  • 40
    • 0027323517 scopus 로고
    • Interleukin 10 production correlates with pathology in human Leishmania donovani infections
    • Ghalib HW, Piuvezam MR, Skeiky YA, Siddig M, Hashim FA, et al. (1993) Interleukin 10 production correlates with pathology in human Leishmania donovani infections. J Clin Invest 92: 324-329.
    • (1993) J Clin Invest , vol.92 , pp. 324-329
    • Ghalib, H.W.1    Piuvezam, M.R.2    Skeiky, Y.A.3    Siddig, M.4    Hashim, F.A.5
  • 41
    • 38449097889 scopus 로고    scopus 로고
    • IL-10- and TGF-beta-mediated susceptibility in kala-azar and post-kala-azar dermal leishmaniasis: the significance of amphotericin B in the control of Leishmania donovani infection in India
    • Saha S, Mondal S, Ravindran R, Bhowmick S, Modak D, et al. (2007) IL-10- and TGF-beta-mediated susceptibility in kala-azar and post-kala-azar dermal leishmaniasis: the significance of amphotericin B in the control of Leishmania donovani infection in India. J Immunol 179: 5592-5603.
    • (2007) J Immunol , vol.179 , pp. 5592-5603
    • Saha, S.1    Mondal, S.2    Ravindran, R.3    Bhowmick, S.4    Modak, D.5
  • 42
    • 0022369062 scopus 로고
    • Absence of gamma interferon and interleukin 2 production during active visceral leishmaniasis
    • Carvalho EM, Badaro R, Reed SG, Jones TC, Johnson WD Jr, (1985) Absence of gamma interferon and interleukin 2 production during active visceral leishmaniasis. J Clin Invest 76: 2066-2069.
    • (1985) J Clin Invest , vol.76 , pp. 2066-2069
    • Carvalho, E.M.1    Badaro, R.2    Reed, S.G.3    Jones, T.C.4    Johnson Jr., W.D.5
  • 43
    • 27744493936 scopus 로고    scopus 로고
    • IL-4 and IL-10 collude in vaccine failure for novel exacerbatory antigens in murine Leishmania major infection
    • Roberts MTM, Stober C, McKenzie AN, Blackwell JM, (2005) IL-4 and IL-10 collude in vaccine failure for novel exacerbatory antigens in murine Leishmania major infection. Infect Immun 73: 7620-7628.
    • (2005) Infect Immun , vol.73 , pp. 7620-7628
    • Roberts, M.T.M.1    Stober, C.2    McKenzie, A.N.3    Blackwell, J.M.4
  • 44
    • 79959853005 scopus 로고    scopus 로고
    • TLR1/2 activation during heterologous prime-boost vaccination (DNA-MVA) enhances CD8+ T Cell responses providing protection against Leishmania (Viannia)
    • Jayakumar A, Castilho TM, Park E, Goldsmith-Pestana K, Blackwell JM, et al. (2011) TLR1/2 activation during heterologous prime-boost vaccination (DNA-MVA) enhances CD8+ T Cell responses providing protection against Leishmania (Viannia). PLoS Negl Trop Dis 5: e1204.
    • (2011) PLoS Negl Trop Dis , vol.5
    • Jayakumar, A.1    Castilho, T.M.2    Park, E.3    Goldsmith-Pestana, K.4    Blackwell, J.M.5
  • 46
    • 0023883155 scopus 로고
    • Cutaneous leishmaniasis: The prospects for a killed vaccine
    • Greenblatt CL, (1988) Cutaneous leishmaniasis: The prospects for a killed vaccine. Parasitol Today 4: 53-54.
    • (1988) Parasitol Today , vol.4 , pp. 53-54
    • Greenblatt, C.L.1
  • 47
    • 0030822043 scopus 로고    scopus 로고
    • Vaccination with DNA encoding the immunodominant LACK parasite antigen confers protective immunity to mice infected with Leishmania major
    • Gurunathan S, Sacks DL, Brown DR, Reiner SL, Charest H, et al. (1997) Vaccination with DNA encoding the immunodominant LACK parasite antigen confers protective immunity to mice infected with Leishmania major. J Exp Med 186: 1137-1147.
    • (1997) J Exp Med , vol.186 , pp. 1137-1147
    • Gurunathan, S.1    Sacks, D.L.2    Brown, D.R.3    Reiner, S.L.4    Charest, H.5
  • 49
    • 17444429293 scopus 로고    scopus 로고
    • Second-generation vaccines against leishmaniasis
    • Coler RN, Reed SG, (2005) Second-generation vaccines against leishmaniasis. Trends Parasitol 21: 244-249.
    • (2005) Trends Parasitol , vol.21 , pp. 244-249
    • Coler, R.N.1    Reed, S.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.