메뉴 건너뛰기




Volumn 23, Issue 11, 2012, Pages 1176-1185

Lentiviral Gene Therapy Against Human Immunodeficiency Virus Type 1, Using a Novel Human TRIM21-Cyclophilin A Restriction Factor

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHILIN A; CYCLOSPORIN; LENTIVIRUS VECTOR; NEUTRALIZING ANTIBODY; TRIPARTITE MOTIF PROTEIN 21 CYCLOPHILIN A; TRIPARTITE MOTIF PROTEIN 5; UNCLASSIFIED DRUG;

EID: 84869007668     PISSN: 10430342     EISSN: 15577422     Source Type: Journal    
DOI: 10.1089/hum.2012.083     Document Type: Article
Times cited : (19)

References (31)
  • 1
    • 33748944362 scopus 로고    scopus 로고
    • Proteasome inhibition reveals that a functional preintegration complex intermediate can be generated during restriction by diverse TRIM5 proteins
    • Anderson, J.L., Campbell, E.M., Wu, X., et al. (2006). Proteasome inhibition reveals that a functional preintegration complex intermediate can be generated during restriction by diverse TRIM5 proteins. J. Virol. 80, 9754-9760.
    • (2006) J. Virol. , vol.80 , pp. 9754-9760
    • Anderson, J.L.1    Campbell, E.M.2    Wu, X.3
  • 2
    • 42149136000 scopus 로고    scopus 로고
    • TRIMCyp expression in Old World primates Macaca nemestrina and Macaca fascicularis
    • Brennan, G., Kozyrev, Y., and Hu, S.L. (2008). TRIMCyp expression in Old World primates Macaca nemestrina and Macaca fascicularis. Proc. Natl. Acad. Sci. U.S.A. 105, 3569-3574.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 3569-3574
    • Brennan, G.1    Kozyrev, Y.2    Hu, S.L.3
  • 3
    • 77953406764 scopus 로고    scopus 로고
    • Extraordinary antigenicity of the human Ro52 autoantigen
    • Burbelo, P.D., Ching, K.H., Han, B.L., et al. (2010). Extraordinary antigenicity of the human Ro52 autoantigen. Am. J. Transl. Res. 2, 145-155.
    • (2010) Am. J. Transl. Res. , vol.2 , pp. 145-155
    • Burbelo, P.D.1    Ching, K.H.2    Han, B.L.3
  • 4
    • 0036252492 scopus 로고    scopus 로고
    • High-level transduction and gene expression in hematopoietic repopulating cells using a human imunodeficiency virus type 1-based lentiviral vector containing an internal spleen focus forming virus promoter
    • Demaison, C., Parsley, K., Brouns, G., et al. (2002). High-level transduction and gene expression in hematopoietic repopulating cells using a human imunodeficiency virus type 1-based lentiviral vector containing an internal spleen focus forming virus promoter. Hum. Gene Ther. 13, 803-813.
    • (2002) Hum. Gene Ther. , vol.13 , pp. 803-813
    • Demaison, C.1    Parsley, K.2    Brouns, G.3
  • 5
    • 85028120068 scopus 로고    scopus 로고
    • Ex-vivo gene therapy restores LEKTI activity and corrects the architecture of Netherton syndrome-derived skin grafts
    • Di, W.L., Larcher, F., Semenova, E., et al. (2011). Ex-vivo gene therapy restores LEKTI activity and corrects the architecture of Netherton syndrome-derived skin grafts. Mol. Ther. 19, 408-416.
    • (2011) Mol. Ther. , vol.19 , pp. 408-416
    • Di, W.L.1    Larcher, F.2    Semenova, E.3
  • 6
    • 79952262602 scopus 로고    scopus 로고
    • Targeted gene editing enters clinic
    • Ledford, H. (2011). Targeted gene editing enters clinic. Nature 471, 16.
    • (2011) Nature , vol.471 , pp. 16
    • Ledford, H.1
  • 7
    • 33751251058 scopus 로고    scopus 로고
    • Gene transfer in humans using a conditionally replicating lentiviral vector
    • Levine, B.L., Humeau, L.M., Boyer, J., et al. (2006). Gene transfer in humans using a conditionally replicating lentiviral vector. Proc. Natl. Acad. Sci. U.S.A. 103, 17372-17377.
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 17372-17377
    • Levine, B.L.1    Humeau, L.M.2    Boyer, J.3
  • 8
    • 33745231723 scopus 로고    scopus 로고
    • Functional replacement of the RING, B-box 2, and coiled-coil domains of tripartite motif 5a (TRIM5a) by heterologous TRIM domains
    • Li, X., Li, Y., Stremlau, M., et al. (2006). Functional replacement of the RING, B-box 2, and coiled-coil domains of tripartite motif 5a (TRIM5a) by heterologous TRIM domains. J. Virol. 80, 6198-6206.
    • (2006) J. Virol. , vol.80 , pp. 6198-6206
    • Li, X.1    Li, Y.2    Stremlau, M.3
  • 9
    • 37549007550 scopus 로고    scopus 로고
    • A novel fusion gene, TRIM5-Cyclophilin A in the pig-tailed macaque determines its susceptibility to HIV-1 infection
    • Liao, C.H., Kuang, Y.Q., Liu, H.L., et al. (2007). A novel fusion gene, TRIM5-Cyclophilin A in the pig-tailed macaque determines its susceptibility to HIV-1 infection. AIDS 21(Suppl. 8), S19-S26.
    • (2007) AIDS , vol.21 , Issue.SUPPL. 8
    • Liao, C.H.1    Kuang, Y.Q.2    Liu, H.L.3
  • 10
    • 78650542340 scopus 로고    scopus 로고
    • Antibodies mediate intracellular immunity through tripartite motif-containing 21 (TRIM21)
    • Mallery, D.L., McEwan, W.A., Bidgood, S.R., et al. (2010). Antibodies mediate intracellular immunity through tripartite motif-containing 21 (TRIM21). Proc. Natl. Acad. Sci. U.S.A. 107, 19985-19990.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 19985-19990
    • Mallery, D.L.1    McEwan, W.A.2    Bidgood, S.R.3
  • 11
    • 62049083710 scopus 로고    scopus 로고
    • Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34+ cells
    • Mitsuyasu, R.T., Merigan, T.C., Carr, A., et al. (2009). Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34+ cells. Nat. Med. 15, 285-292.
    • (2009) Nat. Med. , vol.15 , pp. 285-292
    • Mitsuyasu, R.T.1    Merigan, T.C.2    Carr, A.3
  • 12
    • 70349655695 scopus 로고    scopus 로고
    • Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components
    • Neagu, M.R., Ziegler, P., Pertel, T., et al. (2009). Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components. J. Clin. Invest. 119, 3035-3047.
    • (2009) J. Clin. Invest. , vol.119 , pp. 3035-3047
    • Neagu, M.R.1    Ziegler, P.2    Pertel, T.3
  • 13
    • 40349106167 scopus 로고    scopus 로고
    • Evolution of a TRIM5-CypA splice isoform in Old World monkeys
    • Newman, R.M., Hall, L., Kirmaier, A., et al. (2008). Evolution of a TRIM5-CypA splice isoform in Old World monkeys. PLoS Pathogens 4, e1000003.
    • (2008) PLoS Pathogens , vol.4
    • Newman, R.M.1    Hall, L.2    Kirmaier, A.3
  • 14
    • 4444241947 scopus 로고    scopus 로고
    • A Trim5-cyclophilin A fusion protein found in owl monkey kidney cells can restrictHIV-1
    • Nisole, S., Lynch, C., Stoye, J.P., and Yap,M.W. (2004). A Trim5-cyclophilin A fusion protein found in owl monkey kidney cells can restrictHIV-1. Proc.Natl.Acad. Sci. U.S.A. 101, 13324-13328.
    • (2004) Proc.Natl.Acad. Sci. U.S.A. , vol.101 , pp. 13324-13328
    • Nisole, S.1    Lynch, C.2    Stoye, J.P.3    Yap, M.W.4
  • 15
    • 2642709177 scopus 로고    scopus 로고
    • Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection
    • Palella, F.J., Jr., Delaney, K.M., Moorman, A.C., et al.; HIV Outpatient Study Investigators. (1998). Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. N. Engl. J. Med. 338, 853-860.
    • (1998) N. Engl. J. Med. , vol.338 , pp. 853-860
    • Palella Jr., F.J.1    Delaney, K.M.2    Moorman, A.C.3
  • 16
    • 79955377543 scopus 로고    scopus 로고
    • TRIM5 is an innate immune sensor for the retrovirus capsid lattice
    • Pertel, T., Hausmann, S., Morger, D., et al. (2011). TRIM5 is an innate immune sensor for the retrovirus capsid lattice. Nature 472, 361-365.
    • (2011) Nature , vol.472 , pp. 361-365
    • Pertel, T.1    Hausmann, S.2    Morger, D.3
  • 17
    • 70349807596 scopus 로고    scopus 로고
    • Active site remodeling switches HIV specificity of antiretroviral TRIMCyp
    • Price, A.J., Marzetta, F., Lammers, M., et al. (2009). Active site remodeling switches HIV specificity of antiretroviral TRIMCyp. Nat. Struct. Mol. Biol. 16, 1036-1042.
    • (2009) Nat. Struct. Mol. Biol. , vol.16 , pp. 1036-1042
    • Price, A.J.1    Marzetta, F.2    Lammers, M.3
  • 18
    • 33846294781 scopus 로고    scopus 로고
    • Lentiviral vectors for T-cell suicide gene therapy: Preservation of T-cell effector function after cytokine-mediated transduction
    • Qasim, W., Mackey, T., Sinclair, J., et al. (2007). Lentiviral vectors for T-cell suicide gene therapy: Preservation of T-cell effector function after cytokine-mediated transduction. Mol. Ther. 15, 355-360.
    • (2007) Mol. Ther. , vol.15 , pp. 355-360
    • Qasim, W.1    MacKey, T.2    Sinclair, J.3
  • 20
    • 3242876747 scopus 로고    scopus 로고
    • Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1
    • Sayah, D.M., Sokolskaja, E., Berthoux, L., and Luban, J. (2004). Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1. Nature 430, 569-573.
    • (2004) Nature , vol.430 , pp. 569-573
    • Sayah, D.M.1    Sokolskaja, E.2    Berthoux, L.3    Luban, J.4
  • 21
    • 35348910781 scopus 로고    scopus 로고
    • Fusion of cyclophilin A to Fv1 enables cyclosporine-sensitive restriction of human and feline immunodeficiency viruses
    • Schaller, T., Ylinen, L.M., Webb, B.L., et al. (2007). Fusion of cyclophilin A to Fv1 enables cyclosporine-sensitive restriction of human and feline immunodeficiency viruses. J. Virol. 81, 10055-10063.
    • (2007) J. Virol. , vol.81 , pp. 10055-10063
    • Schaller, T.1    Ylinen, L.M.2    Webb, B.L.3
  • 22
    • 84855278211 scopus 로고    scopus 로고
    • HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency
    • Schaller, T., Ocwieja, K.E., Rasaiyaah, J., et al. (2011). HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency. PLoS Pathogens 7, e1002439.
    • (2011) PLoS Pathogens , vol.7
    • Schaller, T.1    Ocwieja, K.E.2    Rasaiyaah, J.3
  • 23
    • 1542288934 scopus 로고    scopus 로고
    • The cytoplasmic body component TRIM5a restricts HIV-1 infection in Old World monkeys
    • Stremlau, M., Owens, C.M., Perron, M.J., et al. (2004). The cytoplasmic body component TRIM5a restricts HIV-1 infection in Old World monkeys. Nature 427, 848-853.
    • (2004) Nature , vol.427 , pp. 848-853
    • Stremlau, M.1    Owens, C.M.2    Perron, M.J.3
  • 24
    • 34447317534 scopus 로고    scopus 로고
    • The control of viral infection by tripartite motif proteins and cyclophilin A
    • Towers, G.J. (2007). The control of viral infection by tripartite motif proteins and cyclophilin A. Retrovirology 4, 40.
    • (2007) Retrovirology , vol.4 , pp. 40
    • Towers, G.J.1
  • 25
    • 0036168024 scopus 로고    scopus 로고
    • Abrogation of Ref1 retrovirus restriction in human cells
    • Towers, G., Collins, M., Takeuchi, Y. (2002) Abrogation of Ref1 retrovirus restriction in human cells. J Virol. 76, 2548-2550.
    • (2002) J Virol. , vol.76 , pp. 2548-2550
    • Towers, G.1    Collins, M.2    Takeuchi, Y.3
  • 26
    • 34247208235 scopus 로고    scopus 로고
    • Transfer of autologous gene-modified T cells in HIV-infected patients with advanced immunodeficiency and drug-resistant virus
    • van Lunzen, J., Glaunsinger, T., Stahmer, I., et al. (2007). Transfer of autologous gene-modified T cells in HIV-infected patients with advanced immunodeficiency and drug-resistant virus. Mol. Ther. 15, 1024-1033.
    • (2007) Mol. Ther. , vol.15 , pp. 1024-1033
    • Van Lunzen, J.1    Glaunsinger, T.2    Stahmer, I.3
  • 27
    • 67649836071 scopus 로고    scopus 로고
    • Sleeping beauty transposition from nonintegrating lentivirus
    • Vink, C.A., Gaspar, H.B., Gabriel, R., et al. (2009). Sleeping beauty transposition from nonintegrating lentivirus. Mol. Ther. 17, 1197-1204.
    • (2009) Mol. Ther. , vol.17 , pp. 1197-1204
    • Vink, C.A.1    Gaspar, H.B.2    Gabriel, R.3
  • 28
  • 29
    • 42149103799 scopus 로고    scopus 로고
    • Independent evolution of an antiviral TRIMCyp in rhesus macaques
    • Wilson, S.J., Webb, B.L., Ylinen, L.M., et al. (2008a). Independent evolution of an antiviral TRIMCyp in rhesus macaques. Proc. Natl. Acad. Sci. U.S.A. 105, 3557-3562.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 3557-3562
    • Wilson, S.J.1    Webb, B.L.2    Ylinen, L.M.3
  • 30
    • 42149103799 scopus 로고    scopus 로고
    • Independent evolution of an antiviral TRIMCyp in rhesus macaques
    • Wilson, S.J., Webb, B.L., Ylinen, L.M., et al. (2008b). Independent evolution of an antiviral TRIMCyp in rhesus macaques. Proc. Natl. Acad. Sci. U.S.A. 105, 3557-3562.
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 3557-3562
    • Wilson, S.J.1    Webb, B.L.2    Ylinen, L.M.3
  • 31
    • 33646595636 scopus 로고    scopus 로고
    • Proteasome inhibitors uncouple rhesus TRIM5a restriction of HIV-1 reverse transcription and infection
    • Wu, X., Anderson, J.L., Campbell, E.M., et al. (2006). Proteasome inhibitors uncouple rhesus TRIM5a restriction of HIV-1 reverse transcription and infection. Proc. Natl. Acad. Sci. U.S.A. 103, 7465-7470.
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 7465-7470
    • Wu, X.1    Anderson, J.L.2    Campbell, E.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.