Cxcl10 enhances blood cells migration in the sub-ventricular zone of mice affected by experimental autoimmune encephalomyelitis

Molecular and Cellular Neuroscience

Volumn 43, Issue 3, 2010, Pages 268-280

  Muzio, Luca ^a   Cavasinni, Francesca ^a   Marinaro, Cinzia ^a   Bergamaschi, Andrea ^a   Bergami, Alessandra ^a   Porcheri, Cristina ^a   Cerri, Federica ^b   Dina, Giorgia ^b   Quattrini, Angelo ^b   Comi, Giancarlo ^a   Furlan, Roberto ^a   Martino, Gianvito ^a  

^a Institute of Experimental Neurology INSPE   (Italy)

^b Division of Neuroscience   (Italy)

Author keywords

Cxcl10; EAE; Macrophages; Neural stem cell niches; SvZ

Indexed keywords

CALCIUM BINDING PROTEIN; CCL1 CHEMOKINE; CD31 ANTIGEN; CD45 ANTIGEN; CXCL11 CHEMOKINE; CXCL9 CHEMOKINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLIAL FIBRILLARY ACIDIC PROTEIN; IONIZED CALCIUM BINDING ADAPTOR MOLECULE 1; LENTIVIRUS VECTOR; RANTES; STAT1 PROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CD3+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE RELEASE; DEMYELINATION; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; INFLAMMATORY INFILTRATE; LYMPHOCYTIC INFILTRATION; MACROPHAGE MIGRATION; MICROGLIA; MOUSE; MULTIPLE SCLEROSIS; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SUBVENTRICULAR ZONE; T LYMPHOCYTE ACTIVATION; UPREGULATION;

ANIMALS; BONE MARROW TRANSPLANTATION; CELL MOVEMENT; CHEMOKINE CXCL10; CHEMOKINES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; HUMANS; INTERFERON-GAMMA; LYMPHOCYTE ACTIVATION; MACROPHAGES; MICE; MICE, INBRED C57BL; MICROGLIA; MULTIPLE SCLEROSIS; PROSENCEPHALON; T-LYMPHOCYTES; TRANSPLANTATION CHIMERA; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA; MUS;

EID: 76049120423     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2009.11.008     Document Type: Article

References (50)

1. Amadio S., Pluchino S., Brini E., Morana P., Guerriero R., Boneschi F.M., Comi G., Zaratin P., Muzio V., and del Carro U. Motor evoked potentials in a mouse model of chronic multiple sclerosis. Muscle Nerve 33 (2006) 265-273
2. Bartholomaus, IKawakami N., Odoardi F., Schlager C., Miljkovic D., Ellwart J.W., Klinkert W.E., Flugel-Koch C., Issekutz T.B., Wekerle H., and Flugel A. Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions. Nature (2009) 462-94-8
3. Barraud P., Stott S., Mollgard K., Parmar M., and Bjorklund A. In vitro characterization of a human neural progenitor cell coexpressing SSEA4 and CD133. J. Neurosci. Res. 85 (2007) 250-259
4. Belmadani A., Tran P.B., Ren D., and Miller R.J. Chemokines regulate the migration of neural progenitors to sites of neuroinflammation. J. Neurosci. 26 (2006) 3182-3191
5. Butovsky O., Ziv Y., Schwartz A., Landa G., Talpalar A.E., Pluchino S., Martino G., and Schwartz M. Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells. Mol. Cell. Neurosci. 31 (2006) 149-160
6. Centonze D., Muzio L., Rossi S., Cavasinni F., De Chiara V., Bergami A., Musella A., D'Amelio M., Cavallucci V., Martorana A., et al. Inflammation triggers synaptic alteration and degeneration in experimental autoimmune encephalomyelitis. J. Neurosci. 29 (2009) 3442-3452
7. Consiglio A., Quattrini A., Martino S., Bensadoun J.C., Dolcetta D., Trojani A., Benaglia G., Marchesini S., Cestari V., Oliverio A., Bordignon C., and Naldini L. In vivo gene therapy of metachromatic leukodystrophy by lentiviral vectors: correction of neuropathology and protection against learning impairments in affected mice. Nat. Med. (2001) 3-310-316
8. Engelhardt B. The blood-central nervous system barriers actively control immune cell entry into the central nervous system. Curr. Pharm. Des. 14 (2008) 1555-1565
9. Engelhardt B., Wolburg-Buchholz K., and Wolburg H. Involvement of the choroid plexus in central nervous system inflammation. Microsc. Res. Tech. 52 (2001) 112-129
10. Imitola J., Raddassi K., Park K.I., Mueller F.J., Nieto M., Teng Y.D., Frenkel D., Li J., Sidman R.L., Walsh C.A., et al. Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1{alpha}/CXC chemokine receptor 4 pathway. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 18117-18122
11. Kreutzberg G.W. Microglia: a sensor for pathological events in the CNS. Trends Neurosci 19 (1996) 312-318
12. Luster A.D., Unkeless J.C., and Ravetch J.V. Gamma-interferon transcriptionally regulates an early-response gene containing homology to platelet proteins. Nature 315 (1985) 672-676
13. Martino G., and Pluchino S. The therapeutic potential of neural stem cells. Nat. Rev., Neurosci 7 (2006) 395-406
14. Martino G., and Pluchino S. Neural stem cells: guardians of the brain. Nat. Cell Biol. 9 (2007) 1031-1034
15. Mennicken F., Maki R., de Souza E.B., and Quirion R. Chemokines and chemokine receptors in the CNS: a possible role in neuroinflammation and patterning. Trends Pharmacol. Sci. 20 (1999) 73-78
16. Merkler D., Ernsting T., Kerschensteiner M., Bruck W., and Stadelmann C. A new focal EAE model of cortical demyelination: multiple sclerosis-like lesions with rapid resolution of inflammation and extensive remyelination. Brain 129 (2006) 1972-1983
17. Mirzadeh Z., Merkle F.T., Soriano-Navarro M., Garcia-Verdugo J.M., and Alvarez-Buylla A. Neural stem cells confer unique pinwheel architecture to the ventricular surface in neurogenic regions of the adult brain. Cell Stem Cell 3 (2008) 265-278
18. Monje M.L., Toda H., and Palmer T.D. Inflammatory blockade restores adult hippocampal neurogenesis. Science 302 (2003) 1760-1765
19. Owens T., Wekerle H., and Antel J. Genetic models for CNS inflammation. Nat. Med. 7 (2001) 161-166
20. Pluchino S., Quattrini A., Brambilla E., Gritti A., Salani G., Dina G., Galli R., Del Carro U., Amadio S., Bergami A., et al. Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis. Nature 422 (2003) 688-694
21. Pluchino S., Zanotti L., Rossi B., Brambilla E., Ottoboni L., Salani G., Martinello M., Cattalini A., Bergami A., Furlan R., et al. Neurosphere-derived multipotent precursors promote neuroprotection by an immunomodulatory mechanism. Nature 436 (2005) 266-271
22. Pluchino S., Muzio L., Imitola J., Deleidi M., Alfaro-Cervello C., Salani G., Porcheri C., Brambilla E., Cavasinni F., Bergamaschi A., et al. Persistent inflammation alters the function of the endogenous brain stem cell compartment. Brain 131 (2008) 2564-2578
23. Politi L.S., Bacigaluppi M., Brambilla E., Cadioli M., Falini A., Comi G., Scotti G., Martino G., and Pluchino S. Magnetic-resonance-based tracking and quantification of intravenously injected neural stem cell accumulation in the brains of mice with experimental multiple sclerosis. Stem Cells (Dayton, Ohio) 25 (2007) 2583-2592
24. Ransohoff R.M., Kivisakk P., and Kidd G. Three or more routes for leukocyte migration into the central nervous system. Nat. Rev. Immunol. 3 (2003) 569-581
25. Reynolds B.A., and Weiss S. Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 255 (1992) 1707-1710
26. Robin A.M., Zhang Z.G., Wang L., Zhang R.L., Katakowski M., Zhang L., Wang Y., Zhang C., and Chopp M. Stromal cell-derived factor 1alpha mediates neural progenitor cell motility after focal cerebral ischemia. J. Cereb. Blood Flow Metab. 26 (2006) 125-134
27. Salomon I., Netzer N., Wildbaum G., Schif-Zuck S., Maor G., and Karin N. Targeting the function of IFN-gamma-inducible protein 10 suppresses ongoing adjuvant arthritis. J. Immunol. 169 (2002) 2685-2693
28. Sanai N., Tramontin A.D., Quinones-Hinojosa A., Barbaro N.M., Gupta N., Kunwar S., Lawton M.T., McDermott M.W., Parsa A.T., Manuel-Garcia Verdugo J., et al. Unique astrocyte ribbon in adult human brain contains neural stem cells but lacks chain migration. Nature 427 (2004) 740-744
29. Schaefer B.C., Schaefer M.L., Kappler J.W., Marrack P., and Kedl R.M. Observation of antigen-dependent CD8+ T-cell/ dendritic cell interactions in vivo. Cell Immunol. 214 (2001) 110-122
30. Schwartz M., Butovsky O., Bruck W., and Hanisch U.K. Microglial phenotype: is the commitment reversible?. Trends Neurosci. 29 (2006) 68-74
31. Shen Q., Wang Y., Kokovay E., Lin G., Chuang S.M., Goderie S.K., Roysam B., and Temple S. Adult SVZ stem cells lie in a vascular niche: a quantitative analysis of niche cell-cell interactions. Cell Stem Cell 3 (2008) 289-300
32. Simard A.R., and Rivest S. Bone marrow stem cells have the ability to populate the entire central nervous system into fully differentiated parenchymal microglia. FASEB J. 18 (2004) 998-1000
33. Simard A.R., Soulet D., Gowing G., Julien J.P., and Rivest S. Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease. Neuron 49 (2006) 489-502
34. Stamatovic S.M., Keep R.F., Kunkel S.L., and Andjelkovic A.V. Potential role of MCP-1 in endothelial cell tight junction 'opening': signaling via Rho and Rho kinase. J. Cell Sci. 116 (2003) 4615-4628
35. Stamatovic S.M., Shakui P., Keep R.F., Moore B.B., Kunkel S.L., Van Rooijen N., and Andjelkovic A.V. Monocyte chemoattractant protein-1 regulation of blood-brain barrier permeability. J. Cereb. Blood Flow Metab. 25 (2005) 593-606
36. Stark G.R., Kerr I.M., Williams B.R., Silverman R.H., and Schreiber R.D. How cells respond to interferons. Annu. Rev. Biochem. 67 (1998) 227-264
37. Takahashi T., Nowakowski R.S., and Caviness Jr. V.S. BUdR as an S-phase marker for quantitative studies of cytokinetic behaviour in the murine cerebral ventricular zone. J. Neurocytol. 21 (1992) 185-197
38. Takahashi T., Nowakowski R.S., and Caviness Jr. V.S. Cell cycle parameters and patterns of nuclear movement in the neocortical proliferative zone of the fetal mouse. J. Neurosci. 13 (1993) 820-833
39. Takahashi T., Nowakowski R.S., and Caviness Jr. V.S. Mode of cell proliferation in the developing mouse neocortex. Proc. Natl. Acad. Sci. U. S. A. 91 (1994) 375-379
40. Taub D.D., Lloyd A.R., Conlon K., Wang J.M., Ortaldo J.R., Harada A., Matsushima K., Kelvin D.J., and Oppenheim J.J. Recombinant human interferon-inducible protein 10 is a chemoattractant for human monocytes and T lymphocytes and promotes T cell adhesion to endothelial cells. J. Exp. Med. 177 (1993) 1809-1814
41. Tavazoie M., Van der Veken L., Silva-Vargas V., Louissaint M., Colonna L., Zaidi B., Garcia-Verdugo J.M., and Doetsch F. A specialized vascular niche for adult neural stem cells. Cell Stem Cell 3 (2008) 279-288
42. Tran P.B., and Miller R.J. Chemokine receptors: signposts to brain development and disease. Nat. Rev. Neurosci. 4 (2003) 444-455
43. Tran P.B., Ren D., Veldhouse T.J., and Miller R.J. Chemokine receptors are expressed widely by embryonic and adult neural progenitor cells. J. Neurosci. Res. 76 (2004) 20-34
44. Tran P.B., Banisadr G., Ren D., Chenn A., and Miller R.J. Chemokine receptor expression by neural progenitor cells in neurogenic regions of mouse brain. J. Comp. Neurol. 500 (2007) 1007-1033
45. Wang Y., Imitola J., Rasmussen S., O'Connor K.C., and Khoury S.J. Paradoxical dysregulation of the neural stem cell pathway sonic hedgehog-Gli1 in autoimmune encephalomyelitis and multiple sclerosis. Ann. Neurol. 64 (2008) 417-427
46. Wildbaum G., and Karin N. Augmentation of natural immunity to a pro-inflammatory cytokine (TNF-alpha) by targeted DNA vaccine confers long-lasting resistance to experimental autoimmune encephalomyelitis. Gene Ther. 6 (1999) 1128-1138
47. Yeruva S., Ramadori G., and Raddatz D. NF-kappaB-dependent synergistic regulation of CXCL10 gene expression by IL-1beta and IFN-gamma in human intestinal epithelial cell lines. Int. J. Colorectal Dis. 23 (2008) 305-317
48. Yuan H., Gaber M.W., McColgan T., Naimark M.D., Kiani M.F., and Merchant T.E. Radiation-induced permeability and leukocyte adhesion in the rat blood-brain barrier: modulation with anti-ICAM-1 antibodies. Brain Res. 969 (2003) 59-69
49. Ziv Y., Ron N., Butovsky O., Landa G., Sudai E., Greenberg N., Cohen H., Kipnis J., and Schwartz M. Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood. Nat. Neurosci. 9 (2006) 268-275
50. Zou Y.R., Kottmann A.H., Kuroda M., Taniuchi I., and Littman D.R. Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature 393 (1998) 595-599