메뉴 건너뛰기




Volumn 9, Issue 1, 2012, Pages

Blood-brain barrier disruption in CCL2 transgenic mice during pertussis toxin-induced brain inflammation

Author keywords

Central nervous system; Chemokine; Inflammation; Magnetic resonance imaging; Multiple sclerosis

Indexed keywords

DEXTRAN; FLUORESCENT DEXTRAN; GADOLINIUM PENTETATE; MONOCYTE CHEMOTACTIC PROTEIN 1; PERTUSSIS TOXIN; UNCLASSIFIED DRUG;

EID: 84865344876     PISSN: None     EISSN: 20458118     Source Type: Journal    
DOI: 10.1186/2045-8118-9-10     Document Type: Article
Times cited : (28)

References (31)
  • 2
    • 0025342659 scopus 로고
    • Du-Boulay EP, McDonald WI: Heterogeneity of blood-brain barrier changes in multiple sclerosis: an MRI study with gadolinium-DTPA enhancement
    • 10.1212/WNL.40.2.229, 2300240
    • Kermode AG, Tofts PS, Thompson AJ, MacManus DG, Rudge P, Kendall BE, Kingsley DP, Moseley IF. du-Boulay EP, McDonald WI: Heterogeneity of blood-brain barrier changes in multiple sclerosis: an MRI study with gadolinium-DTPA enhancement. Neurology 1990, 40:229-235. 10.1212/WNL.40.2.229, 2300240.
    • (1990) Neurology , vol.40 , pp. 229-235
    • Kermode, A.G.1    Tofts, P.S.2    Thompson, A.J.3    MacManus, D.G.4    Rudge, P.5    Kendall, B.E.6    Kingsley, D.P.7    Moseley, I.F.8
  • 3
    • 0015333994 scopus 로고
    • Cerebral vascular permeability and cellular infiltration in experimental allergic encephalomyelitis
    • 1407847, 5021707
    • Leibowitz S, Kennedy L. Cerebral vascular permeability and cellular infiltration in experimental allergic encephalomyelitis. Immunology 1972, 22:859-869. 1407847, 5021707.
    • (1972) Immunology , vol.22 , pp. 859-869
    • Leibowitz, S.1    Kennedy, L.2
  • 4
    • 0021164553 scopus 로고
    • Blood-brain and blood-spinal cord barrier permeability during the course of experimental allergic encephalomyelitis in the rat
    • 10.1016/0006-8993(84)90249-X, 6610460
    • Juhler M, Barry DI, Offner H, Konat G, Klinken L, Paulson OB. Blood-brain and blood-spinal cord barrier permeability during the course of experimental allergic encephalomyelitis in the rat. Brain Res 1984, 302:347-355. 10.1016/0006-8993(84)90249-X, 6610460.
    • (1984) Brain Res , vol.302 , pp. 347-355
    • Juhler, M.1    Barry, D.I.2    Offner, H.3    Konat, G.4    Klinken, L.5    Paulson, O.B.6
  • 5
    • 0021326142 scopus 로고
    • Blood-brain barrier in chronic relapsing experimental allergic encephalomyelitis: a correlative study between cerebrospinal fluid protein concentrations and tracer leakage in the central nervous system
    • 10.1007/BF00688469, 6730912
    • Kitz K, Lassmann H, Karcher D, Lowenthal A. Blood-brain barrier in chronic relapsing experimental allergic encephalomyelitis: a correlative study between cerebrospinal fluid protein concentrations and tracer leakage in the central nervous system. Acta Neuropathol 1984, 63:41-50. 10.1007/BF00688469, 6730912.
    • (1984) Acta Neuropathol , vol.63 , pp. 41-50
    • Kitz, K.1    Lassmann, H.2    Karcher, D.3    Lowenthal, A.4
  • 6
    • 0025218689 scopus 로고
    • Du-Boulay EP, Landon DN, McDonald WI: Duration and selectivity of blood-brain barrier breakdown in chronic relapsing experimental allergic encephalomyelitis studied by gadolinium-DTPA and protein markers
    • 10.1093/brain/113.2.365, 2328409
    • Hawkins CP, Munro PM, MacKenzie F, Kesselring J, Tofts PS. du-Boulay EP, Landon DN, McDonald WI: Duration and selectivity of blood-brain barrier breakdown in chronic relapsing experimental allergic encephalomyelitis studied by gadolinium-DTPA and protein markers. Brain 1990, 113:365-378. 10.1093/brain/113.2.365, 2328409.
    • (1990) Brain , vol.113 , pp. 365-378
    • Hawkins, C.P.1    Munro, P.M.2    MacKenzie, F.3    Kesselring, J.4    Tofts, P.S.5
  • 7
    • 0025906369 scopus 로고
    • Patterns of blood-brain barrier breakdown in inflammatory demyelination
    • 10.1093/brain/114.2.801, 2043950
    • Hawkins CP, MacKenzie F, Tofts P, du Boulay BE, McDonald WI. Patterns of blood-brain barrier breakdown in inflammatory demyelination. Brain 1991, 114:801-810. 10.1093/brain/114.2.801, 2043950.
    • (1991) Brain , vol.114 , pp. 801-810
    • Hawkins, C.P.1    MacKenzie, F.2    Tofts, P.3    du Boulay, B.E.4    McDonald, W.I.5
  • 11
    • 0037300319 scopus 로고    scopus 로고
    • The role of MCP-1 (CCL2) and CCR2 in multiple sclerosis and experimental autoimmune encephalomyelitis (EAE)
    • 10.1016/S1044-5323(02)00125-2, 12495638
    • Mahad DJ, Ransohoff RM. The role of MCP-1 (CCL2) and CCR2 in multiple sclerosis and experimental autoimmune encephalomyelitis (EAE). Semin Immunol 2003, 15:23-32. 10.1016/S1044-5323(02)00125-2, 12495638.
    • (2003) Semin Immunol , vol.15 , pp. 23-32
    • Mahad, D.J.1    Ransohoff, R.M.2
  • 12
    • 0032100683 scopus 로고    scopus 로고
    • MCP-1, MCP-2 and MCP-3 expression in multiple sclerosis lesions: an immunohistochemical and in situ hybridization study
    • 10.1016/S0165-5728(98)00002-2, 9655469
    • McManus C, Berman JW, Brett FM, Staunton H, Farrell M, Brosnan CF. MCP-1, MCP-2 and MCP-3 expression in multiple sclerosis lesions: an immunohistochemical and in situ hybridization study. J Neuroimmunol 1998, 86:20-29. 10.1016/S0165-5728(98)00002-2, 9655469.
    • (1998) J Neuroimmunol , vol.86 , pp. 20-29
    • McManus, C.1    Berman, J.W.2    Brett, F.M.3    Staunton, H.4    Farrell, M.5    Brosnan, C.F.6
  • 13
    • 0032522207 scopus 로고    scopus 로고
    • Expression of monocyte chemoattractant protein-1 and other beta-chemokines by resident glia and inflammatory cells in multiple sclerosis lesions
    • 10.1016/S0165-5728(97)00208-7, 9628469
    • Simpson JE, Newcombe J, Cuzner ML, Woodroofe MN. Expression of monocyte chemoattractant protein-1 and other beta-chemokines by resident glia and inflammatory cells in multiple sclerosis lesions. J Neuroimmunol 1998, 84:238-249. 10.1016/S0165-5728(97)00208-7, 9628469.
    • (1998) J Neuroimmunol , vol.84 , pp. 238-249
    • Simpson, J.E.1    Newcombe, J.2    Cuzner, M.L.3    Woodroofe, M.N.4
  • 14
    • 0032920496 scopus 로고    scopus 로고
    • Expression of MCP-1 by reactive astrocytes in demyelinating multiple sclerosis lesions
    • 10.1016/S0002-9440(10)65249-2, 1853444, 9916917
    • Van Der Voorn P, Tekstra J, Beelen RH, Tensen CP, Van Der Valk P, De Groot CJ. Expression of MCP-1 by reactive astrocytes in demyelinating multiple sclerosis lesions. Am J Pathol 1999, 154:45-51. 10.1016/S0002-9440(10)65249-2, 1853444, 9916917.
    • (1999) Am J Pathol , vol.154 , pp. 45-51
    • Van Der Voorn, P.1    Tekstra, J.2    Beelen, R.H.3    Tensen, C.P.4    Van Der Valk, P.5    De Groot, C.J.6
  • 16
    • 0041319041 scopus 로고    scopus 로고
    • Chemokine expression by glial cells directs leukocytes to sites of axonal injury in the CNS
    • Babcock AA, Kuziel WA, Rivest S, Owens T. Chemokine expression by glial cells directs leukocytes to sites of axonal injury in the CNS. J Neurosci 2003, 23:7922-7930.
    • (2003) J Neurosci , vol.23 , pp. 7922-7930
    • Babcock, A.A.1    Kuziel, W.A.2    Rivest, S.3    Owens, T.4
  • 17
    • 0028841168 scopus 로고
    • Controlled recruitment of monocytes and macrophages to specific organs through transgenic expression of monocyte chemoattractant protein-1
    • Fuentes ME, Durham SK, Swerdel MR, Lewin AC, Barton DS, Megill JR, Bravo R, Lira SA. Controlled recruitment of monocytes and macrophages to specific organs through transgenic expression of monocyte chemoattractant protein-1. J Immunol 1995, 155:5769-5776.
    • (1995) J Immunol , vol.155 , pp. 5769-5776
    • Fuentes, M.E.1    Durham, S.K.2    Swerdel, M.R.3    Lewin, A.C.4    Barton, D.S.5    Megill, J.R.6    Bravo, R.7    Lira, S.A.8
  • 18
    • 33750837704 scopus 로고    scopus 로고
    • Metalloproteinases control brain inflammation induced by pertussis toxin in mice overexpressing the chemokine CCL2 in the central nervous system
    • Toft-Hansen H, Buist R, Sun XJ, Schellenberg A, Peeling J, Owens T. Metalloproteinases control brain inflammation induced by pertussis toxin in mice overexpressing the chemokine CCL2 in the central nervous system. J Immunol 2006, 177:7242-7249.
    • (2006) J Immunol , vol.177 , pp. 7242-7249
    • Toft-Hansen, H.1    Buist, R.2    Sun, X.J.3    Schellenberg, A.4    Peeling, J.5    Owens, T.6
  • 19
    • 58149402415 scopus 로고    scopus 로고
    • Perivascular spaces and the two steps to neuroinflammation
    • 10.1097/NEN.0b013e31818f9ca8, 19018243
    • Owens T, Bechmann I, Engelhardt B. Perivascular spaces and the two steps to neuroinflammation. J Neuropathol Exp Neurol 2008, 67:1113-1121. 10.1097/NEN.0b013e31818f9ca8, 19018243.
    • (2008) J Neuropathol Exp Neurol , vol.67 , pp. 1113-1121
    • Owens, T.1    Bechmann, I.2    Engelhardt, B.3
  • 20
    • 0017807683 scopus 로고
    • Vascular permeability changes in the central nervous system of rats with hyperacute experimental allergic encephalomyelitis induced with the aid of a substance from Bordetella pertussis
    • 422039, 211087
    • Bergman RK, Munoz JJ, Portis JL. Vascular permeability changes in the central nervous system of rats with hyperacute experimental allergic encephalomyelitis induced with the aid of a substance from Bordetella pertussis. Infect Immun 1978, 21:627-637. 422039, 211087.
    • (1978) Infect Immun , vol.21 , pp. 627-637
    • Bergman, R.K.1    Munoz, J.J.2    Portis, J.L.3
  • 21
    • 16344368162 scopus 로고    scopus 로고
    • Diapedesis of mononuclear cells across cerebral venules during experimental autoimmune encephalomyelitis leaves tight junctions intact
    • 10.1007/s00401-004-0928-x, 15549331
    • Wolburg H, Wolburg-Buchholz K, Engelhardt B. Diapedesis of mononuclear cells across cerebral venules during experimental autoimmune encephalomyelitis leaves tight junctions intact. Acta Neuropathol 2005, 109:181-190. 10.1007/s00401-004-0928-x, 15549331.
    • (2005) Acta Neuropathol , vol.109 , pp. 181-190
    • Wolburg, H.1    Wolburg-Buchholz, K.2    Engelhardt, B.3
  • 22
    • 0347989376 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 alters expression of tight junction-associated proteins in brain microvascular endothelial cells
    • 10.1016/j.mvr.2003.07.001, 14709405
    • Song L, Pachter JS. Monocyte chemoattractant protein-1 alters expression of tight junction-associated proteins in brain microvascular endothelial cells. Microvasc Res 2004, 67:78-89. 10.1016/j.mvr.2003.07.001, 14709405.
    • (2004) Microvasc Res , vol.67 , pp. 78-89
    • Song, L.1    Pachter, J.S.2
  • 24
    • 33646823302 scopus 로고    scopus 로고
    • Protein kinase Calpha-RhoA cross-talk in CCL2-induced alterations in brain endothelial permeability
    • 10.1074/jbc.M513122200, 16439355
    • Stamatovic SM, Dimitrijevic OB, Keep RF, Andjelkovic AV. Protein kinase Calpha-RhoA cross-talk in CCL2-induced alterations in brain endothelial permeability. J Biol Chem 2006, 281:8379-8388. 10.1074/jbc.M513122200, 16439355.
    • (2006) J Biol Chem , vol.281 , pp. 8379-8388
    • Stamatovic, S.M.1    Dimitrijevic, O.B.2    Keep, R.F.3    Andjelkovic, A.V.4
  • 25
    • 17544401216 scopus 로고    scopus 로고
    • Permeabilization in a cerebral endothelial barrier model by pertussis toxin involves the PKC effector pathway and is abolished by elevated levels of cAMP
    • 10.1242/jcs.00378, 12665564
    • Bruckener KE, el Baya A, Galla HJ, Schmidt MA. Permeabilization in a cerebral endothelial barrier model by pertussis toxin involves the PKC effector pathway and is abolished by elevated levels of cAMP. J Cell Sci 2003, 116:1837-1846. 10.1242/jcs.00378, 12665564.
    • (2003) J Cell Sci , vol.116 , pp. 1837-1846
    • Bruckener, K.E.1    el Baya, A.2    Galla, H.J.3    Schmidt, M.A.4
  • 26
    • 0020446988 scopus 로고
    • Acute experimental autoimmune encephalomyelitis in mice. I. Adjuvant action of Bordetella pertussis is due to vasoactive amine sensitization and increased vascular permeability of the central nervous system
    • 10.1016/0008-8749(82)90457-9, 6891621
    • Linthicum DS, Munoz JJ, Blaskett A. Acute experimental autoimmune encephalomyelitis in mice. I. Adjuvant action of Bordetella pertussis is due to vasoactive amine sensitization and increased vascular permeability of the central nervous system. Cell Immunol 1982, 73:299-310. 10.1016/0008-8749(82)90457-9, 6891621.
    • (1982) Cell Immunol , vol.73 , pp. 299-310
    • Linthicum, D.S.1    Munoz, J.J.2    Blaskett, A.3
  • 27
    • 0027279416 scopus 로고
    • Enhancement of histamine-induced vascular leakage by pertussis toxin in SJL/J mice but not BALB/c mice
    • 10.1016/0165-5728(93)90162-R, 8331165
    • Yong T, Meininger GA, Linthicum DS. Enhancement of histamine-induced vascular leakage by pertussis toxin in SJL/J mice but not BALB/c mice. J Neuroimmunol 1993, 45:47-52. 10.1016/0165-5728(93)90162-R, 8331165.
    • (1993) J Neuroimmunol , vol.45 , pp. 47-52
    • Yong, T.1    Meininger, G.A.2    Linthicum, D.S.3
  • 28
    • 0035966659 scopus 로고    scopus 로고
    • Comparison of the timing of acute blood-brain barrier breakdown to rabbit immunoglobulin G in the cerebellum and spinal cord of mice with experimental autoimmune encephalomyelitis
    • 10.1002/1096-9861(20010129)430:1<131::AID-CNE1019>3.0.CO;2-K, 11135250
    • Tonra JR, Reiseter BS, Kolbeck R, Nagashima K, Robertson R, Keyt B, Lindsay RM. Comparison of the timing of acute blood-brain barrier breakdown to rabbit immunoglobulin G in the cerebellum and spinal cord of mice with experimental autoimmune encephalomyelitis. J Comp Neurol 2001, 430:131-144. 10.1002/1096-9861(20010129)430:1<131::AID-CNE1019>3.0.CO;2-K, 11135250.
    • (2001) J Comp Neurol , vol.430 , pp. 131-144
    • Tonra, J.R.1    Reiseter, B.S.2    Kolbeck, R.3    Nagashima, K.4    Robertson, R.5    Keyt, B.6    Lindsay, R.M.7
  • 29
    • 0027326873 scopus 로고
    • Thrombin may contribute to the pathophysiology of central nervous system injury
    • 10.1089/neu.1993.10.167, 7692071
    • Nishino A, Suzuki M, Ohtani H, Motohashi O, Umezawa K, Nagura H, Yoshimoto T. Thrombin may contribute to the pathophysiology of central nervous system injury. J Neurotrauma 1993, 10:167-179. 10.1089/neu.1993.10.167, 7692071.
    • (1993) J Neurotrauma , vol.10 , pp. 167-179
    • Nishino, A.1    Suzuki, M.2    Ohtani, H.3    Motohashi, O.4    Umezawa, K.5    Nagura, H.6    Yoshimoto, T.7
  • 30
    • 0030897819 scopus 로고    scopus 로고
    • Mechanisms of edema formation after intracerebral hemorrhage: effects of thrombin on cerebral blood flow, blood-brain barrier permeability, and cell survival in a rat model
    • 10.3171/jns.1997.86.2.0272, 9010429
    • Lee KR, Kawai N, Kim S, Sagher O, Hoff JT. Mechanisms of edema formation after intracerebral hemorrhage: effects of thrombin on cerebral blood flow, blood-brain barrier permeability, and cell survival in a rat model. J Neurosurg 1997, 86:272-278. 10.3171/jns.1997.86.2.0272, 9010429.
    • (1997) J Neurosurg , vol.86 , pp. 272-278
    • Lee, K.R.1    Kawai, N.2    Kim, S.3    Sagher, O.4    Hoff, J.T.5
  • 31
    • 0036656798 scopus 로고    scopus 로고
    • Pathophysiology of brain edema formation
    • 10.1016/S1042-3680(02)00007-4, 12486926
    • Xi G, Keep RF, Hoff JT. Pathophysiology of brain edema formation. Neurosurg Clin N Am 2002, 13:371-383. 10.1016/S1042-3680(02)00007-4, 12486926.
    • (2002) Neurosurg Clin N Am , vol.13 , pp. 371-383
    • Xi, G.1    Keep, R.F.2    Hoff, J.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.