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Volumn 38, Issue 2, 2012, Pages 318-325

The substance P/neurokinin-1 receptor system in lung cancer: Focus on the antitumor action of neurokinin-1 receptor antagonists

Author keywords

Apoptosis; Aprepitant; L 732,138; L 733,060; Non small cell lung cancer; Small cell lung cancer

Indexed keywords

APREPITANT; NEUROKININ 1 RECEPTOR; NEUROKININ 1 RECEPTOR ANTAGONIST; SMALL INTERFERING RNA; SUBSTANCE P;

EID: 84868700225     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2012.09.024     Document Type: Article
Times cited : (66)

References (33)
  • 1
    • 65649138814 scopus 로고    scopus 로고
    • A constitutively active form of neurokinin 1 receptor and neurokinin 1 receptor-mediated apoptosis in glioblastomas
    • T. Akazawa, S.G. Kwatra, L.E. Goldsmith, M.D. Richardson, E.A. Cox, and J.H. Sampom A constitutively active form of neurokinin 1 receptor and neurokinin 1 receptor-mediated apoptosis in glioblastomas J Neurochem 109 2009 1079 1086
    • (2009) J Neurochem , vol.109 , pp. 1079-1086
    • Akazawa, T.1    Kwatra, S.G.2    Goldsmith, L.E.3    Richardson, M.D.4    Cox, E.A.5    Sampom, J.H.6
  • 2
    • 77958174965 scopus 로고    scopus 로고
    • Aprepitant use in children, adolescents, and young adults for the control of chemotherapy-induced nausea and vomiting (CINV)
    • M.R. Choi, C. Jiles, and N.L. Seibel Aprepitant use in children, adolescents, and young adults for the control of chemotherapy-induced nausea and vomiting (CINV) J Pediatr Hematol Oncol 32 2010 e268 e271
    • (2010) J Pediatr Hematol Oncol , vol.32
    • Choi, M.R.1    Jiles, C.2    Seibel, N.L.3
  • 3
    • 0033856662 scopus 로고    scopus 로고
    • Syndecan-1 expression is up-regulated in pancreatic but not in other gastrointestinal cancers
    • J.R. Conejo, J. Kleeff, A. Koliopanos, K. Matsuda, Z.W. Zhu, and H. Goecke Syndecan-1 expression is up-regulated in pancreatic but not in other gastrointestinal cancers Int J Cancer 88 2000 12 20
    • (2000) Int J Cancer , vol.88 , pp. 12-20
    • Conejo, J.R.1    Kleeff, J.2    Koliopanos, A.3    Matsuda, K.4    Zhu, Z.W.5    Goecke, H.6
  • 4
    • 0034718604 scopus 로고    scopus 로고
    • The proliferative and antiapoptotic effects of substance P are facilitated by formation of a beta-arrestin-dependent scaffolding complex
    • K.A. DeFea, Z.D. Vaughn, E.M. O'Bryan, D. Nishijima, O. Dery, and N.W. Bunnett The proliferative and antiapoptotic effects of substance P are facilitated by formation of a beta-arrestin-dependent scaffolding complex Proc Natl Acad Sci USA 97 2000 11086 11091
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 11086-11091
    • Defea, K.A.1    Vaughn, Z.D.2    O'Bryan, E.M.3    Nishijima, D.4    Dery, O.5    Bunnett, N.W.6
  • 5
    • 33646558897 scopus 로고    scopus 로고
    • A role for substance P in cancer promotion and progression: A mechanism to counteract intracellular death signals following oncogene activation or DNA damage
    • F. Esteban, M. Muñoz, M.A. González-Moles, and M. Rosso A role for substance P in cancer promotion and progression: a mechanism to counteract intracellular death signals following oncogene activation or DNA damage Cancer Metast Rev 25 2006 137 145
    • (2006) Cancer Metast Rev , vol.25 , pp. 137-145
    • Esteban, F.1    Muñoz, M.2    González-Moles, M.A.3    Rosso, M.4
  • 6
    • 0027281553 scopus 로고
    • Stimulation of angiogenesis by substance P an interleukin-1 in the rat and its inhibition by NK1 or interleukin-1 receptor antagonists
    • T.P. Fan, D.E. Hu, S. Guard, G.A. Gresham, and K.J. Watling Stimulation of angiogenesis by substance P an interleukin-1 in the rat and its inhibition by NK1 or interleukin-1 receptor antagonists Br J Pharmacol 110 1993 43 49
    • (1993) Br J Pharmacol , vol.110 , pp. 43-49
    • Fan, T.P.1    Hu, D.E.2    Guard, S.3    Gresham, G.A.4    Watling, K.J.5
  • 7
    • 0038137331 scopus 로고    scopus 로고
    • Neurokinin-1 receptor expression and its potential effects on tumor growth in human pancreatic cancer
    • H. Friess, Z. Zhu, V. Liard, X. Shi, S.V. Shrikhande, and L. Wang Neurokinin-1 receptor expression and its potential effects on tumor growth in human pancreatic cancer Lab Invest 83 2003 731 742
    • (2003) Lab Invest , vol.83 , pp. 731-742
    • Friess, H.1    Zhu, Z.2    Liard, V.3    Shi, X.4    Shrikhande, S.V.5    Wang, L.6
  • 9
    • 0029071971 scopus 로고
    • Substance-P receptors in human primary neoplasms: Tumoral and vascular localization
    • I.M. Hennig, J.A. Laissue, U. Horisberger, and J.C. Reubi Substance-P receptors in human primary neoplasms: tumoral and vascular localization Int J Cancer 61 1995 786 792
    • (1995) Int J Cancer , vol.61 , pp. 786-792
    • Hennig, I.M.1    Laissue, J.A.2    Horisberger, U.3    Reubi, J.C.4
  • 10
    • 43649108815 scopus 로고    scopus 로고
    • Targeting growth factors in lung cancer
    • P.H. Hodkinson, A. MacKinnon, and T. Sethi Targeting growth factors in lung cancer Chest 133 2008 1209 1216
    • (2008) Chest , vol.133 , pp. 1209-1216
    • Hodkinson, P.H.1    MacKinnon, A.2    Sethi, T.3
  • 11
    • 4544321026 scopus 로고    scopus 로고
    • Induction of a metastatogenic tumor cell type by neurotransmitters and its pharmacological inhibition by established drugs
    • K. Lang, T.L. Drell, A. Lindecke, B. Niggemann, C. Kaltschmidt, and K.S. Zaenker Induction of a metastatogenic tumor cell type by neurotransmitters and its pharmacological inhibition by established drugs Int J Cancer 112 2004 231 238
    • (2004) Int J Cancer , vol.112 , pp. 231-238
    • Lang, K.1    Drell, T.L.2    Lindecke, A.3    Niggemann, B.4    Kaltschmidt, C.5    Zaenker, K.S.6
  • 12
    • 0026801445 scopus 로고
    • Broad spectrum neuropeptide antagonists inhibit the growth of small cell lung cancer in vivo
    • S. Langdon, T. Sethi, A. Ritchie, M. Muir, J. Smyth, and E. Rozengurt Broad spectrum neuropeptide antagonists inhibit the growth of small cell lung cancer in vivo Cancer Res 52 1992 4554 4557
    • (1992) Cancer Res , vol.52 , pp. 4554-4557
    • Langdon, S.1    Sethi, T.2    Ritchie, A.3    Muir, M.4    Smyth, J.5    Rozengurt, E.6
  • 13
    • 0029961467 scopus 로고
    • Substance P-induced mitogenesis in human astrocytoma cells correlates with activation of the mitogen-activated protein kinase signaling pathway
    • W. Luo, T.R. Sharif, and M. Sharif Substance P-induced mitogenesis in human astrocytoma cells correlates with activation of the mitogen-activated protein kinase signaling pathway Cancer Res 56 1995 4983 4991
    • (1995) Cancer Res , vol.56 , pp. 4983-4991
    • Luo, W.1    Sharif, T.R.2    Sharif, M.3
  • 14
    • 66149137995 scopus 로고    scopus 로고
    • Neurokinin 1 receptor mediates membrane blebbing in HEK293 cells through a Rho/Rho-associated coiled-coil kinase-dependent mechanism
    • J. Meshki, S.D. Douglas, J.P. Lai, L. Schwartz, L.E. Kilpatrick, and F. Tuluc Neurokinin 1 receptor mediates membrane blebbing in HEK293 cells through a Rho/Rho-associated coiled-coil kinase-dependent mechanism J Biol Chem 284 2009 9280 9289
    • (2009) J Biol Chem , vol.284 , pp. 9280-9289
    • Meshki, J.1    Douglas, S.D.2    Lai, J.P.3    Schwartz, L.4    Kilpatrick, L.E.5    Tuluc, F.6
  • 16
    • 84861738830 scopus 로고    scopus 로고
    • The NK-1 receptor is expressed in human leukemia and is involved in the antitumor action of aprepitant and other NK-1 receptor antagonists on acute lymphoblastic leukemia cell lines
    • M. Muñoz, A. González-Ortega, and R. Coveñas The NK-1 receptor is expressed in human leukemia and is involved in the antitumor action of aprepitant and other NK-1 receptor antagonists on acute lymphoblastic leukemia cell lines Invest New Drugs 30 2012 529 540
    • (2012) Invest New Drugs , vol.30 , pp. 529-540
    • Muñoz, M.1    González-Ortega, A.2    Coveñas, R.3
  • 17
    • 3042799978 scopus 로고    scopus 로고
    • Antitumoural action of NK1 receptor antagonist L-733,060 on human melanoma cell lines
    • M. Muñoz, A. Pérez, M. Rosso, C. Zamarriego, and R. Rosso Antitumoural action of NK1 receptor antagonist L-733,060 on human melanoma cell lines Melanoma Res 14 2004 183 188
    • (2004) Melanoma Res , vol.14 , pp. 183-188
    • Muñoz, M.1    Pérez, A.2    Rosso, M.3    Zamarriego, C.4    Rosso, R.5
  • 18
    • 40549118238 scopus 로고    scopus 로고
    • NK-1 receptor antagonists induce apoptosis and counteract substance P-related mitogenesis in human laryngeal cancer cell line HEp-2
    • M. Muñoz, M. Rosso, F.J. Aguilar, M.A. González-Moles, M. Redondo, and F. Esteban NK-1 receptor antagonists induce apoptosis and counteract substance P-related mitogenesis in human laryngeal cancer cell line HEp-2 Invest New Drugs 26 2008 111 118
    • (2008) Invest New Drugs , vol.26 , pp. 111-118
    • Muñoz, M.1    Rosso, M.2    Aguilar, F.J.3    González-Moles, M.A.4    Redondo, M.5    Esteban, F.6
  • 19
    • 77950639335 scopus 로고    scopus 로고
    • A new frontier in the treatment of cancer: NK-1 receptor antagonists
    • M. Muñoz, M. Rosso, and R. Coveñas A new frontier in the treatment of cancer: NK-1 receptor antagonists Curr Med Chem 17 2010 504 516
    • (2010) Curr Med Chem , vol.17 , pp. 504-516
    • Muñoz, M.1    Rosso, M.2    Coveñas, R.3
  • 20
    • 79953669021 scopus 로고    scopus 로고
    • The NK-1 receptor: A new target in cancer therapy
    • M. Muñoz, M. Rosso, and R. Coveñas The NK-1 receptor: a new target in cancer therapy Curr Drug Targets 12 2011 909 921
    • (2011) Curr Drug Targets , vol.12 , pp. 909-921
    • Muñoz, M.1    Rosso, M.2    Coveñas, R.3
  • 21
    • 34347273792 scopus 로고    scopus 로고
    • Neurokinin-1 receptors located in human retinoblastoma cell lines: Antitumor action of its antagonist, L-732,138
    • M. Muñoz, M. Rosso, R. Coveñas, I. Montero, M.A. González-Moles, and M.J. Robles Neurokinin-1 receptors located in human retinoblastoma cell lines: antitumor action of its antagonist, L-732,138 Invest Ophthalmol Vis Sci 48 2007 2775 2781
    • (2007) Invest Ophthalmol Vis Sci , vol.48 , pp. 2775-2781
    • Muñoz, M.1    Rosso, M.2    Coveñas, R.3    Montero, I.4    González-Moles, M.A.5    Robles, M.J.6
  • 22
    • 23044450652 scopus 로고    scopus 로고
    • The NK1 receptor is involved in the antitumoural action of L-733,060 and in the mitogenic action of substance P on neuroblastoma and glioma cell lines
    • M. Muñoz, M. Rosso, A. Pérez, R. Coveñas, C. Zamarriego, and J.I. Piruat The NK1 receptor is involved in the antitumoural action of L-733,060 and in the mitogenic action of substance P on neuroblastoma and glioma cell lines Neuropeptides 39 2005 427 432
    • (2005) Neuropeptides , vol.39 , pp. 427-432
    • Muñoz, M.1    Rosso, M.2    Pérez, A.3    Coveñas, R.4    Zamarriego, C.5    Piruat, J.I.6
  • 23
    • 77955151651 scopus 로고    scopus 로고
    • The NK-1 receptor is expressed in human melanoma and is involved in the antitumor action of the NK-1 receptor antagonist aprepitant on melanoma cell lines
    • M. Muñoz, M. Rosso, M.J. Robles-Frias, M.V. Salinas-Martín, and R. Coveñas The NK-1 receptor is expressed in human melanoma and is involved in the antitumor action of the NK-1 receptor antagonist aprepitant on melanoma cell lines Lab Invest 90 2010 1259 1269
    • (2010) Lab Invest , vol.90 , pp. 1259-1269
    • Muñoz, M.1    Rosso, M.2    Robles-Frias, M.J.3    Salinas-Martín, M.V.4    Coveñas, R.5
  • 24
    • 33747199597 scopus 로고    scopus 로고
    • Tachykinins and their receptors in human malignancies
    • C. Palma Tachykinins and their receptors in human malignancies Curr Drug Targets 7 2006 1043 1052
    • (2006) Curr Drug Targets , vol.7 , pp. 1043-1052
    • Palma, C.1
  • 25
    • 0032920530 scopus 로고    scopus 로고
    • Substance P activates responses correlated with tumor growth in human glioma cells line bearing tachykinin NK1 receptors
    • C. Palma, F. Nardelli, S. Manzini, and C.A. Maggi Substance P activates responses correlated with tumor growth in human glioma cells line bearing tachykinin NK1 receptors Br J Cancer 79 1999 236 243
    • (1999) Br J Cancer , vol.79 , pp. 236-243
    • Palma, C.1    Nardelli, F.2    Manzini, S.3    Maggi, C.A.4
  • 26
    • 0028174947 scopus 로고
    • 11] Substance P induces apoptosis in lung cancer cell lines in vitro
    • 11] Substance P induces apoptosis in lung cancer cell lines in vitro Biochem Biophys Res Commun 199 1994 1313 1319
    • (1994) Biochem Biophys Res Commun , vol.199 , pp. 1313-1319
    • Reeve, J.G.1    Bleehen, N.M.2
  • 27
    • 0037937249 scopus 로고    scopus 로고
    • Enhancement of angiogenesis by endogenous substance P release and neurokinin-1 receptors during neurogenic inflammation
    • H.C. Seegers, V.C. Hood, B.L. Kidd, S.C. Cruwys, and D.A. Walsch Enhancement of angiogenesis by endogenous substance P release and neurokinin-1 receptors during neurogenic inflammation J Pharmacol Exp Ther 306 2003 8 12
    • (2003) J Pharmacol Exp Ther , vol.306 , pp. 8-12
    • Seegers, H.C.1    Hood, V.C.2    Kidd, B.L.3    Cruwys, S.C.4    Walsch, D.A.5
  • 28
    • 0026681259 scopus 로고
    • Growth of small cell lung cancer cells: Stimulation by multiple neuropeptides and inhibition by broad spectrum antagonists in vitro and in vivo
    • T. Sethi, S. Langdon, J. Smyth, and E. Rozengurt Growth of small cell lung cancer cells: stimulation by multiple neuropeptides and inhibition by broad spectrum antagonists in vitro and in vivo Cancer Res 52 1992 2737 2742
    • (1992) Cancer Res , vol.52 , pp. 2737-2742
    • Sethi, T.1    Langdon, S.2    Smyth, J.3    Rozengurt, E.4
  • 30
    • 0034602721 scopus 로고    scopus 로고
    • Increased expression of preprotachykinin-I and neurokinin receptors in human breast cancer cells: Implications for bone marrow metastasis
    • D. Singh, D.D. Joshi, M. Hameed, J. Qian, P. Gascón, and P.B. Maloof Increased expression of preprotachykinin-I and neurokinin receptors in human breast cancer cells: implications for bone marrow metastasis Proc Natl Acad Sci USA 97 2000 1388 1393
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 1388-1393
    • Singh, D.1    Joshi, D.D.2    Hameed, M.3    Qian, J.4    Gascón, P.5    Maloof, P.B.6
  • 31
    • 0029848744 scopus 로고    scopus 로고
    • Innervation and neurokinin receptors during angiogenesis in the rat sponge granuloma
    • D.A. Walsh, D.E. Hu, P.I. Mapp, J.M. Polak, D.R. Blake, and T.P. Fan Innervation and neurokinin receptors during angiogenesis in the rat sponge granuloma J Histochem Cytochem 28 1996 759 769
    • (1996) J Histochem Cytochem , vol.28 , pp. 759-769
    • Walsh, D.A.1    Hu, D.E.2    Mapp, P.I.3    Polak, J.M.4    Blake, D.R.5    Fan, T.P.6
  • 32
    • 0024163078 scopus 로고
    • 11] substance P, a potent bombesin antagonist in murine Swiss 3T3 cells, inhibits the growth of human small cell lung cancer cells in vitro
    • 11] substance P, a potent bombesin antagonist in murine Swiss 3T3 cells, inhibits the growth of human small cell lung cancer cells in vitro Proc Natl Acad Sci USA 85 1988 1859 1863
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 1859-1863
    • Woll, P.J.1    Rozengurt, E.2


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