Neurokinin 1 receptor mediates membrane blebbing in HEK293 cells through a Rho/Rho-associated coiled-coil kinase-dependent mechanism

Journal of Biological Chemistry

Volumn 284, Issue 14, 2009, Pages 9280-9289

  Meshki, John ^a   Douglas, Steven D ^a,b   Lai, Jian Ping ^a   Schwartz, Lynnae ^a   Kilpatrick, Laurie E ^a,b   Tuluc, Florin ^a,b,c  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; APOPTOTIC CELL DEATH; CELL SHAPES; CELL-PERMEABLE; CELLULAR MORPHOLOGY; COILED COIL; ELECTRICAL IMPEDANCE; HEK293 CELLS; INTRACELLULAR CALCIUM; KINASE INHIBITORS; MEMBRANE BLEBBING; MYOSIN LIGHT CHAIN KINASE; PHOSPHOLIPASE C; PRE-INCUBATION; PROTEIN KINASE C; PROTEIN KINASE C INHIBITORS; RECEPTOR-LIGAND INTERACTIONS; SHAPE CHANGE; SUBSTANCE-P;

CALCIUM; CALCIUM ALLOYS; CELL DEATH; MONOLAYERS; PLANTS (BOTANY);

CELL MEMBRANES;

1 (5 CHLORO 1 NAPHTHALENESULFONYL)HEXAHYDRO 1H 1,4 DIAZEPINE; 1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; APREPITANT; CALCIUM; EXOENZYME C3; LIGAND; NEUROKININ 1 RECEPTOR; NEUROKININ 1 RECEPTOR ANTAGONIST; PROTEIN KINASE C; RHO KINASE; SUBSTANCE P; MYOSIN LIGHT CHAIN; MYOSIN LIGHT CHAIN PHOSPHATASE; PROTEIN KINASE INHIBITOR; RHO GUANINE NUCLEOTIDE BINDING PROTEIN;

APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CELL SHAPE; CELL STRAIN HEK293; CELL STRUCTURE; CONTROLLED STUDY; ELECTRON MICROSCOPY; FLOW CYTOMETRY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMPEDANCE; PRIORITY JOURNAL; PROTEIN INTERACTION; WESTERN BLOTTING; CELL LINE; CELL MEMBRANE; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; INTRACELLULAR SPACE; METABOLISM; PHOSPHORYLATION; SIGNAL TRANSDUCTION; ULTRASTRUCTURE;

APOPTOSIS; CALCIUM; CELL LINE; CELL MEMBRANE; CELL SHAPE; HUMANS; INTRACELLULAR SPACE; MICROSCOPY, ELECTRON; MYOSIN LIGHT CHAINS; MYOSIN-LIGHT-CHAIN PHOSPHATASE; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; RECEPTORS, NEUROKININ-1; RHO GTP-BINDING PROTEINS; RHO-ASSOCIATED KINASES; SIGNAL TRANSDUCTION;

EID: 66149137995     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M808825200     Document Type: Article

References (60)

1. Lai, J. P., Douglas, S. D., and Ho, W. Z. (1998) J. Neuroimmunol. 86, 80-86
2. Ho, W. Z., Lai, J. P., Li, Y., and Douglas, S. D. (2002) FASEB J. 16, 616-618
3. Ho, W. Z., Lai, J. P., Zhu, X. H., Uvaydova, M., and Douglas, S. D. (1997) J. Immunol. 159, 5654-5660
4. Guo, C. J., Lai, J. P., Luo, H. M., Douglas, S. D., and Ho, W. Z. (2002) J. Neuroimmunol. 131, 160-167
5. Reed, K. L., Fruin, A. B., Gower, A. C., Stucchi, A. F., Leeman, S. E., and Becker, J. M. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 9115-9120
6. Weinstock, J. V., Blum, A., Metwali, A., Elliott, D., Bunnett, N., and Arsenescu, R. (2003) J. Immunol. 171, 3762-3767
7. Singh, L. K., Pang, X., Alexacos, N., Letourneau, R., and Theoharides, T. C. (1999) Brain Behav. Immun. 13, 225-239
8. Severini, C., Improta, G., Falconieri-Erspamer, G., Salvadori, S., and Erspamer, V. (2002) Pharmacol. Rev. 54, 285-322
9. Lai, J. P., Ho, W. Z., Kilpatrick, L. E., Wang, X., Tuluc, F., Korchak, H. M., and Douglas, S. D. (2006) Proc. Natl. Acad. Sci. U. S. A. 103, 7771-7776
10. Lai, J. P., Lai, S., Tuluc, F., Tansky, M. F., Kilpatrick, L. E., Leeman, S. E., and Douglas, S. D. (2008) Proc. Natl. Acad. Sci. U. S. A. 105, 12605-12610
11. Fong, T. M., Anderson, S. A., Yu, H., Huang, R. R., and Strader, C. D. (1992) Mol. Pharmacol. 41, 24-30
12. Chernova, I., Lai, J. P., Li, H., Schwartz, L., Tuluc, F., Korchak, H. M., Douglas, S. D., and Kilpatrick, L. E. (2009) J. Leukocyte Biol. 85, 154-164
13. Khawaja, A. M., and Rogers, D. F. (1996) Int. J. Biochem. Cell Biol. 28, 721-738
14. Kwatra, M. M., Schwinn, D. A., Schreurs, J., Blank, J. L., Kim, C. M., Benovic, J. L., Krause, J. E., Caron, M. G., and Lefkowitz, R. J. (1993) J. Biol. Chem. 268, 9161-9164
15. Nakajima, Y., Tsuchida, K., Negishi, M., Ito, S., and Nakanishi, S. (1992) J. Biol. Chem. 267, 2437-2442
16. Laniyonu, A., Sliwinski-Lis, E., and Fleming, N. (1988) FEBS Lett. 240, 186-190
17. Yang, Y. L., Yao, K. H., and Li, Z. W. (2003) Brain Res. 991, 18-25
18. Schratzberger, P., Reinisch, N., Prodinger, W. M., Kahler, C. M., Sitte, B. A., Bellmann, R., Fischer-Colbrie, R., Winkler, H., and Wiedermann, C. J. (1997) J. Immunol. 158, 3895-3901
19. Rittner, H. L., Lux, C., Labuz, D., Mousa, S. A., Schafer, M., Stein, C., and Brack, A. (2007) Anesthesiology 107, 1009-1017
20. Ruff, M. R., Wahl, S. M., and Pert, C. B. (1985) Peptides 6, Suppl. 2, 107-111
21. Dunzendorfer, S., Meierhofer, C., and Wiedermann, C. J. (1998) J. Leukocyte Biol. 64, 828-834
22. Koyama, S., Sato, E., Nomura, H., Kubo, K., Nagai, S., and Izumi, T. (1998) J. Appl. Physiol. 84, 1528-1534
23. Feistritzer, C., Clausen, J., Sturn, D. H., Djanani, A., Gunsilius, E., Wiedermann, C. J., and Kahler, C. M. (2003) Regul. Pept. 116, 119-126
24. Esteban, F., Munoz, M., Gonzalez-Moles, M. A., and Rosso, M. (2006) Cancer Metastasis Rev. 25, 137-145
25. DeFea, K. A., Vaughn, Z. D., O'Bryan, E. M., Nishijima, D., Dery, O., and Bunnett, N. W. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 11086-11091
26. Amantini, C., Mosca, M., Lucciarini, R., Perfumi, M. C., and Santoni, G. (2008) J. Pharmacol. Exp. Ther. 327, 215-225
27. Park, S. W., Yan, Y. P., Satriotomo, I., Vemuganti, R., and Dempsey, R. J. (2007) J. Neurosurg. 107, 593-599
28. Sebbagh, M., Renvoize, C., Hamelin, J., Riche, N., Bertoglio, J., and Breard, J. (2001) Nat. Cell Biol. 3, 346-352
29. Koga, Y., and Ikebe, M. (2008) Mol. Biol. Cell 19, 1062-1071
30. Eto, M., Kirkbride, J. A., and Brautigan, D. L. (2005) Cell Motil. Cytoskeleton 62, 100-109
31. Coleman, M. L., Sahai, E. A., Yeo, M., Bosch, M., Dewar, A., and Olson, M. F. (2001) Nat. Cell Biol. 3, 339-345
32. Mills, J. C., Stone, N. L., Erhardt, J., and Pittman, R. N. (1998) J. Cell Biol. 140, 627-636
33. Fackler, O. T., and Grosse, R. (2008) J. Cell Biol. 181, 879-884
34. Grynkiewicz, G., Poenie, M., and Tsien, R. Y. (1985) J. Biol. Chem. 260, 3440-3450
35. Gudima, S., He, Y., Meier, A., Chang, J., Chen, R., Jarnik, M., Nicolas, E., Bruss, V., and Taylor, J. (2007) J. Virol. 81, 3608-3617
36. Yu, N., Atienza, J. M., Bernard, J., Blanc, S., Zhu, J., Wang, X., Xu, X., and Abassi, Y. A. (2006) Anal. Chem. 78, 35-43
37. Schachter, J. B., Sromek, S. M., Nicholas, R. A., and Harden, T. K. (1997) Neuropharmacology 36, 1181-1187
38. Gao, S. Y., Li, C. Y., Chen, J., Pan, L., Saito, S., Terashita, T., Saito, K., Miyawaki, K., Shigemoto, K., Mominoki, K., Matsuda, S., and Kobayashi, N. (2004) Nephron 97, e49-e61
39. Leverrier, Y., and Ridley, A. J. (2001) Nat. Cell Biol. 3, E91-E93
40. Paluch, E., Sykes, C., Prost, J., and Bornens, M. (2006) Trends Cell Biol. 16, 5-10
41. Uehata, M., Ishizaki, T., Satoh, H., Ono, T., Kawahara, T., Morishita, T., Tamakawa, H., Yamagami, K., Inui, J., Maekawa, M., and Narumiya, S. (1997) Nature 389, 990-994
42. Totsukawa, G., Wu, Y., Sasaki, Y., Hartshorne, D. J., Yamakita, Y., Yamashiro, S., and Matsumura, F. (2004) J. Cell Biol. 164, 427-439
43. Shimizu, H., Ito, M., Miyahara, M., Ichikawa, K., Okubo, S., Konishi, T., Naka, M., Tanaka, T., Hirano, K., Hartshorne, D. J., et al. (1994) J. Biol. Chem. 269, 30407-30411
44. Shirazi, A., Iizuka, K., Fadden, P., Mosse, C., Somlyo, A. P., Somlyo, A. V., and Haystead, T. A. (1994) J. Biol. Chem. 269, 31598-31606
45. Charras, G. T. (2008) J. Microsc. (Oxf.) 231, 466-478
46. Charras, G. T., Hu, C. K., Coughlin, M., and Mitchison, T. J. (2006) J. Cell Biol. 175, 477-490
47. Martin, S. J., O'Brien, G. A., Nishioka, W. K., McGahon, A. J., Mahboubi, A., Saido, T. C., and Green, D. R. (1995) J. Biol. Chem. 270, 6425-6428
48. Amano, M., Fukata, Y., and Kaibuchi, K. (2000) Exp. Cell Res. 261, 44-51
49. Amano, M., Ito, M., Kimura, K., Fukata, Y., Chihara, K., Nakano, T., Matsuura, Y., and Kaibuchi, K. (1996) J. Biol. Chem. 271, 20246-20249
50. Williams, M. (1987) Annu. Rev. Pharmacol. Toxicol. 27, 315-345
51. Weisman, G. A., Yu, N., Liao, Z., Gonzalez, F., Erb, L., and Seye, C. I. (2006) Biotechnol. Genet. Eng. Rev. 22, 171-195
52. Morelli, A., Chiozzi, P., Chiesa, A., Ferrari, D., Sanz, J. M., Falzoni, S., Pinton, P., Rizzuto, R., Olson, M. F., and Di Virgilio, F. (2003) Mol. Biol. Cell 14, 2655-2664
53. Mizuta, K., Gallos, G., Zhu, D., Mizuta, F., Goubaeva, F., Xu, D., Panettieri, R. A., Jr., Yang, J., and Emala, C. W., Sr. (2008) Am. J. Physiol. 294, L523-L534
54. Barr, A. J., Brass, L. F., and Manning, D. R. (1997) J. Biol. Chem. 272, 2223-2229
55. Bian, D., Mahanivong, C., Yu, J., Frisch, S. M., Pan, Z. K., Ye, R. D., and Huang, S. (2006) Oncogene 25, 2234-2244
56. Nguyen, Q. D., Faivre, S., Bruyneel, E., Rivat, C., Seto, M., Endo, T., Mareel, M., Emami, S., and Gespach, C. (2002) FASEB J. 16, 565-576
57. Kurose, H. (2003) Life Sci. 74, 155-161
58. Riddick, N., Ohtani, K., and Surks, H. K. (2008) J. Cell. Biochem. 103, 1158-1170
59. Gutjahr, M. C., Rossy, J., and Niggli, V. (2005) Exp. Cell Res. 308, 422-438
60. Vemuri, G. S., Zhang, J., Huang, R., Keen, J. H., and Rittenhouse, S. E. (1996) Biochem. J. 314, 805-810