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Volumn 122, Issue 11, 2012, Pages 4203-4212

Obesity-programmed mice are rescued by early genetic intervention

Author keywords

[No Author keywords available]

Indexed keywords

PROOPIOMELANOCORTIN; TAMOXIFEN;

EID: 84868618690     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI62543     Document Type: Article
Times cited : (87)

References (44)
  • 1
    • 77950020302 scopus 로고    scopus 로고
    • WHO Geneva, Switzerland: World Health Organization
    • WHO. Factsheet no. 311: Obesity and Overweight. Geneva, Switzerland: World Health Organization; 2011.
    • (2011) Factsheet No. 311: Obesity and Overweight
  • 2
    • 25844457693 scopus 로고    scopus 로고
    • Obesity
    • DOI 10.1016/S0140-6736(05)67483-1, PII S0140673605674831
    • Haslam DW, James WP. Obesity. Lancet. 2005;366(9492):1197-1209. (Pubitemid 41393598)
    • (2005) Lancet , vol.366 , Issue.9492 , pp. 1197-1209
    • Haslam, D.W.1    James, W.P.T.2
  • 3
    • 58149480226 scopus 로고    scopus 로고
    • Molecular physiology of weight regulation in mice and humans
    • Leibel RL. Molecular physiology of weight regulation in mice and humans. Int J Obes (Lond). 2008;32(suppl 7):S98-S108.
    • (2008) Int J Obes (Lond) , vol.32 , Issue.SUPPL. 7
    • Leibel, R.L.1
  • 5
    • 0028127126 scopus 로고
    • Recovery of initial body weight and composition after long-term massive overfeeding in men
    • Pasquet P, Apfelbaum M. Recovery of initial body weight and composition after long-term massive overfeeding in men. Am J Clin Nutr. 1994;60(6):861-863. (Pubitemid 24377266)
    • (1994) American Journal of Clinical Nutrition , vol.60 , Issue.6 , pp. 861-863
    • Pasquet, P.1    Apfelbaum, M.2
  • 7
    • 70149113665 scopus 로고    scopus 로고
    • Adaptive reduction in thermogenesis and resistance to lose fat in obese men
    • Tremblay A, Chaput JP. Adaptive reduction in thermogenesis and resistance to lose fat in obese men. Br J Nutr. 2009;102(4):488-492.
    • (2009) Br J Nutr , vol.102 , Issue.4 , pp. 488-492
    • Tremblay, A.1    Chaput, J.P.2
  • 8
    • 34249821944 scopus 로고    scopus 로고
    • Pharmacological treatment of the overweight patient
    • DOI 10.1124/pr.59.2.2
    • Bray GA, Greenway FL. Pharmacological treatment of the overweight patient. Pharmacol Rev. 2007;59(2):151-184. (Pubitemid 46855438)
    • (2007) Pharmacological Reviews , vol.59 , Issue.2 , pp. 151-184
    • Bray, G.A.1    Greenway, F.L.2
  • 9
    • 78349310530 scopus 로고    scopus 로고
    • Long-term weight loss maintenance in the United States
    • Kraschnewski JL, et al. Long-term weight loss maintenance in the United States. Int J Obes (Lond). 2010;34(11):1644-1654.
    • (2010) Int J Obes (Lond) , vol.34 , Issue.11 , pp. 1644-1654
    • Kraschnewski, J.L.1
  • 10
    • 34250155983 scopus 로고    scopus 로고
    • Increases in morbid obesity in the USA: 2000-2005
    • DOI 10.1016/j.puhe.2007.01.006, PII S0033350607000121
    • Sturm R. Increases in morbid obesity in the USA: 2000-2005. Public Health. 2007;121(7):492-496. (Pubitemid 46895458)
    • (2007) Public Health , vol.121 , Issue.7 , pp. 492-496
    • Sturm, R.1
  • 11
    • 0018908253 scopus 로고
    • Persistent obesity in rats following a period of consumption of a mixed, high energy diet
    • Rolls BJ, Rowe EA, Turner RC. Persistent obesity in rats following a period of consumption of a mixed, high energy diet. J Physiol. 1980;298:415-427. (Pubitemid 10111744)
    • (1980) Journal of Physiology , vol.VOL 298 , pp. 415-427
    • Rolls, B.J.1    Rowe, E.A.2    Turner, R.C.3
  • 13
    • 65549169894 scopus 로고    scopus 로고
    • Persistent diet-induced obesity in male C57BL/6 mice resulting from temporary obesigenic diets
    • Guo J, Jou W, Gavrilova O, Hall KD. Persistent diet-induced obesity in male C57BL/6 mice resulting from temporary obesigenic diets. PLoS One. 2009;4(4):e5370.
    • (2009) PLoS One , vol.4 , Issue.4
    • Guo, J.1    Jou, W.2    Gavrilova, O.3    Hall, K.D.4
  • 14
    • 0037220421 scopus 로고    scopus 로고
    • Allostasis: A neural behavioral perspective
    • DOI 10.1016/S0018-506X(02)00035-1
    • Schulkin J. Allostasis: a neural behavioral perspective. Horm Behav. 2003;43(1):21-27. (Pubitemid 36293271)
    • (2003) Hormones and Behavior , vol.43 , Issue.1 , pp. 21-27
    • Schulkin, J.1
  • 15
    • 66049102943 scopus 로고    scopus 로고
    • The control of food intake: Behavioral versus molecular perspectives
    • Woods SC. The control of food intake: behavioral versus molecular perspectives. Cell Metab. 2009;9(6):489-498.
    • (2009) Cell Metab , vol.9 , Issue.6 , pp. 489-498
    • Woods, S.C.1
  • 16
    • 34147119799 scopus 로고    scopus 로고
    • The Hormonal Control of Food Intake
    • DOI 10.1016/j.cell.2007.04.001, PII S0092867407004473
    • Coll AP, Farooqi IS, O'Rahilly S. The hormonal control of food intake. Cell. 2007;129(2):251-262. (Pubitemid 46574977)
    • (2007) Cell , vol.129 , Issue.2 , pp. 251-262
    • Coll, A.P.1    Farooqi, I.S.2    O'Rahilly, S.3
  • 17
    • 27844481977 scopus 로고    scopus 로고
    • Subfunctionalization of expression and peptide domains following the ancient duplication of the proopiomelanocortin gene in teleost fishes
    • DOI 10.1093/molbev/msi236
    • de Souza FS, Bumaschny VF, Low MJ, Rubinstein M. Subfunctionalization of expression and peptide domains following the ancient duplication of the proopiomelanocortin gene in teleost fishes. Mol Biol Evol. 2005;22(12):2417- 2427. (Pubitemid 41661378)
    • (2005) Molecular Biology and Evolution , vol.22 , Issue.12 , pp. 2417-2427
    • De Souza, F.S.J.1    Bumaschny, V.F.2    Low, M.J.3    Rubinstein, M.4
  • 18
    • 16244381143 scopus 로고    scopus 로고
    • Identification of neuronal enhancers of the proopiomelanocortin gene by transgenic mouse analysis and phylogenetic footprinting
    • de Souza FS, et al. Identification of neuronal enhancers of the proopiomelanocortin gene by transgenic mouse analysis and phylogenetic footprinting. Mol Cell Biol. 2005;25(8):3076-3086.
    • (2005) Mol Cell Biol , vol.25 , Issue.8 , pp. 3076-3086
    • De Souza, F.S.1
  • 21
    • 0032863468 scopus 로고    scopus 로고
    • Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin
    • DOI 10.1038/12506
    • Yaswen L, Diehl N, Brennan MB, Hochgeschwender U. Obesity in the mouse model of proopiomelanocortin deficiency responds to peripheral melanocortin. Nat Med. 1999;5(9):1066-1070. (Pubitemid 29439581)
    • (1999) Nature Medicine , vol.5 , Issue.9 , pp. 1066-1070
    • Yaswen, L.1    Diehl, N.2    Brennan, M.B.3    Hochgeschwender, U.4
  • 22
    • 0031838353 scopus 로고    scopus 로고
    • Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans
    • DOI 10.1038/509
    • Krude H, Biebermann H, Luck W, Horn R, Brabant G, Gruters A. Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans. Nat Genet. 1998;19(2):155-157. (Pubitemid 28248796)
    • (1998) Nature Genetics , vol.19 , Issue.2 , pp. 155-157
    • Krude, H.1    Biebermann, H.2    Luck, W.3    Horn, R.4    Brabant, G.5    Gruters, A.6
  • 23
    • 77951666149 scopus 로고    scopus 로고
    • Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats
    • Johnson PM, Kenny PJ. Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats. Nat Neurosci. 2010;13(5):635-641.
    • (2010) Nat Neurosci , vol.13 , Issue.5 , pp. 635-641
    • Johnson, P.M.1    Kenny, P.J.2
  • 25
    • 0037090881 scopus 로고    scopus 로고
    • Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: A tool for temporally regulated gene activation/inactivation in the mouse
    • DOI 10.1006/dbio.2002.0597
    • Hayashi S, McMahon AP. Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse. Dev Biol. 2002;244(2):305-318. (Pubitemid 34450645)
    • (2002) Developmental Biology , vol.244 , Issue.2 , pp. 305-318
    • Hayashi, S.1    McMahon, A.P.2
  • 26
    • 74249095268 scopus 로고    scopus 로고
    • Central leptin receptor action and resistance in obesity
    • Bjorbaek C. Central leptin receptor action and resistance in obesity. J Investig Med. 2009;57(7):789-794.
    • (2009) J Investig Med , vol.57 , Issue.7 , pp. 789-794
    • Bjorbaek, C.1
  • 27
    • 35948981635 scopus 로고    scopus 로고
    • Ancient exaptation of a CORE-SINE retroposon into a highly conserved mammalian neuronal enhancer of the proopiomelanocortin gene
    • DOI 10.1371/journal.pgen.0030166
    • Santangelo AM, de Souza FS, Franchini LF, Bumaschny VF, Low MJ, Rubinstein M. Ancient exaptation of a CORE-SINE retroposon into a highly conserved mammalian neuronal enhancer of the proopiomelanocortin gene. PLoS Genet. 2007;3(10):1813-1826. (Pubitemid 350072048)
    • (2007) PLoS Genetics , vol.3 , Issue.10 , pp. 1813-1826
    • Santangelo, A.M.1    De Souza, F.S.J.2    Franchini, L.F.3    Bumaschny, V.F.4    Low, M.J.5    Rubinstein, M.6
  • 29
    • 79551555006 scopus 로고    scopus 로고
    • Melanocortin-4 receptors expressed by cholinergic neurons regulate energy balance and glucose homeostasis
    • Rossi J, et al. Melanocortin-4 receptors expressed by cholinergic neurons regulate energy balance and glucose homeostasis. Cell Metab. 2011;13(2):195-204.
    • (2011) Cell Metab , vol.13 , Issue.2 , pp. 195-204
    • Rossi, J.1
  • 30
    • 38449087113 scopus 로고    scopus 로고
    • In vivo evidence for inverse agonism of Agouti-related peptide in the central nervous system of proopiomelanocortin-deficient mice
    • Tolle V, Low MJ. In vivo evidence for inverse agonism of Agouti-related peptide in the central nervous system of proopiomelanocortin-deficient mice. Diabetes. 2008;57(1):86-94.
    • (2008) Diabetes , vol.57 , Issue.1 , pp. 86-94
    • Tolle, V.1    Low, M.J.2
  • 31
    • 77449101244 scopus 로고    scopus 로고
    • A recurring problem with the analysis of energy expenditure in genetic models expressing lean and obese phenotypes
    • Butler AA, Kozak LP. A recurring problem with the analysis of energy expenditure in genetic models expressing lean and obese phenotypes. Diabetes. 2010;59(2):323-329.
    • (2010) Diabetes , vol.59 , Issue.2 , pp. 323-329
    • Butler, A.A.1    Kozak, L.P.2
  • 32
    • 78751532080 scopus 로고    scopus 로고
    • Toward a more complete (and less controversial) understanding of energy expenditure and its role in obesity pathogenesis
    • Kaiyala KJ, Schwartz MW. Toward a more complete (and less controversial) understanding of energy expenditure and its role in obesity pathogenesis. Diabetes. 2011;60(1):17-23.
    • (2011) Diabetes , vol.60 , Issue.1 , pp. 17-23
    • Kaiyala, K.J.1    Schwartz, M.W.2
  • 36
    • 80052922112 scopus 로고    scopus 로고
    • Hunger states switch a flip-flop memory circuit via a synaptic AMPK-dependent positive feedback loop
    • Yang Y, Atasoy D, Su HH, Sternson SM. Hunger states switch a flip-flop memory circuit via a synaptic AMPK-dependent positive feedback loop. Cell. 2011;146(6):992-1003.
    • (2011) Cell , vol.146 , Issue.6 , pp. 992-1003
    • Yang, Y.1    Atasoy, D.2    Su, H.H.3    Sternson, S.M.4
  • 37
    • 43549114292 scopus 로고    scopus 로고
    • Mechanisms of leptin action and leptin resistance
    • DOI 10.1146/annurev.physiol.70.113006.100707
    • Myers MG, Cowley MA, Munzberg H. Mechanisms of leptin action and leptin resistance. Annu Rev Physiol. 2008;70:537-556. (Pubitemid 351738191)
    • (2008) Annual Review of Physiology , vol.70 , pp. 537-556
    • Myers, M.G.1    Cowley, M.A.2    Munzberg, H.3
  • 38
    • 33845867730 scopus 로고    scopus 로고
    • Inactivation of signal transducer and activator of transcription 3 in proopiomelanocortin (Pomc) neurons causes decreased Pomc expression, mild obesity, and defects in compensatory refeeding
    • DOI 10.1210/en.2006-1119
    • Xu AW, Ste-Marie L, Kaelin CB, Barsh GS. Inactivation of signal transducer and activator of transcription 3 in proopiomelanocortin (Pomc) neurons causes decreased pomc expression, mild obesity, and defects in compensatory refeeding. Endocrinology. 2007;148(1):72-80. (Pubitemid 46021439)
    • (2007) Endocrinology , vol.148 , Issue.1 , pp. 72-80
    • Xu, A.W.1    Ste-Marie, L.2    Kaelin, C.B.3    Barsh, G.S.4
  • 39
    • 0242694039 scopus 로고    scopus 로고
    • Gender Differences in the Control of Energy Homeostasis
    • Woods SC, Gotoh K, Clegg DJ. Gender differences in the control of energy homeostasis. Exp Biol Med (Maywood). 2003;228(10):1175-1180. (Pubitemid 37413676)
    • (2003) Experimental Biology and Medicine , vol.228 , Issue.10 , pp. 1175-1180
    • Woods, S.C.1    Gotoh, K.2    Clegg, D.J.3
  • 40
    • 0344406153 scopus 로고    scopus 로고
    • Differential sensitivity to central leptin and insulin in male and female rats
    • DOI 10.2337/diabetes.52.3.682
    • Clegg DJ, Riedy CA, Smith KA, Benoit SC, Woods SC. Differential sensitivity to central leptin and insulin in male and female rats. Diabetes. 2003;52(3):682-687. (Pubitemid 36323575)
    • (2003) Diabetes , vol.52 , Issue.3 , pp. 682-687
    • Clegg, D.J.1    Riedy, C.A.2    Smith, K.A.B.3    Benoit, S.C.4    Woods, S.C.5
  • 42
    • 79955934209 scopus 로고    scopus 로고
    • The estrogen receptor alpha colocalizes with proopiomelanocortin in hypothalamic neurons and binds to a conserved motif present in the neuron-specific enhancer nPE2
    • de Souza FS, Nasif S, Lopez-Leal R, Levi DH, Low MJ, Rubinsten M. The estrogen receptor alpha colocalizes with proopiomelanocortin in hypothalamic neurons and binds to a conserved motif present in the neuron-specific enhancer nPE2. Eur J Pharmacol. 2011;660(1):181-187.
    • (2011) Eur J Pharmacol , vol.660 , Issue.1 , pp. 181-187
    • De Souza, F.S.1    Nasif, S.2    Lopez-Leal, R.3    Levi, D.H.4    Low, M.J.5    Rubinsten, M.6
  • 44
    • 0034842640 scopus 로고    scopus 로고
    • Site- and time-specific gene targeting in the mouse
    • DOI 10.1006/meth.2001.1159
    • Metzger D, Chambon P. Site- and time-specific gene targeting in the mouse. Methods. 2001;24(1):71-80. (Pubitemid 32846445)
    • (2001) Methods , vol.24 , Issue.1 , pp. 71-80
    • Metzger, D.1    Chambon, P.2


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