Expression of the runt homology domain of RUNX1 disrupts homeostasis of hematopoietic stem cells and induces progression to myelodysplastic syndrome

Blood

Volumn 120, Issue 19, 2012, Pages 4028-4037

  Matsuura, Shinobu ^a,d   Komeno, Yukiko ^a   Stevenson, Kristen E ^b   Biggs, Joseph R ^a   Lam, Kentson ^a   Tang, Tingdong ^a   Lo, Miao Chia ^a   Cong, Xiuli ^a   Yan, Ming ^a   Neuberg, Donna S ^b   Zhang, Dong Er ^a,c  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR RUNX1;

ACUTE GRANULOCYTIC LEUKEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DISEASE COURSE; FLOW CYTOMETRY; GENE EXPRESSION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; MOUSE; MYELODYSPLASTIC SYNDROME; NEUTROPHIL; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 84868606172     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-01-404533     Document Type: Article

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