Stable complex formation between serine protease inhibitor and zymogen: Coagulation factor X cleaves the Arg393-Ser394 bond in a reactive centre loop of antithrombin in the presence of heparin

Journal of Biochemistry

Volumn 152, Issue 5, 2012, Pages 463-470

  Nakatomi, Yasushi ^a   Tsuji, Manami ^a   Gokudan, Soutaro ^a   Hanada Dateki, Takako ^a   Nakashima, Teruhisa ^a   Miyazaki, Hiroki ^a   Hamamoto, Takayoshi ^a   Nakagaki, Tomohiro ^a   Tomokiyo, Kazuhiko ^a  

^a Kaketsuken   (Japan)

Author keywords

antithrombin; factor X; heparin; SDS stable complex; serpin

Indexed keywords

ANTITHROMBIN; ARGININE; BLOOD CLOTTING FACTOR 10; ENZYME PRECURSOR; HEPARIN; LOW MOLECULAR WEIGHT HEPARIN; PENTASACCHARIDE; SERINE; SERINE PROTEINASE INHIBITOR;

AMINO TERMINAL SEQUENCE; ARTICLE; CHEMICAL BOND; COMPLEX FORMATION; GEL PERMEATION CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MOLECULAR WEIGHT; POLYACRYLAMIDE GEL ELECTROPHORESIS; SEQUENCE ANALYSIS;

ANTITHROMBINS; ARGININE; ENZYME PRECURSORS; FACTOR X; HEPARIN; HUMANS; SERINE; SERINE PROTEINASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84868583648     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvs094     Document Type: Article

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