Nuclear envelope-associated dynein drives prophase centrosome separation and enables Eg5-independent bipolar spindle formation

EMBO Journal

Volumn 31, Issue 21, 2012, Pages 4179-4190

  Raaijmakers, Jonne A ^a,b   Van Heesbeen, Roy G H P ^a,b   Meaders, Johnathan L ^a   Geers, Erica F ^a   Fernandez Garcia, Belen ^a   Medema, René H ^a,b   Tanenbaum, Marvin E ^a,c  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

centrosome separation; dynein; Eg5; resistance; spindle

Indexed keywords

DYNEIN ADENOSINE TRIPHOSPHATASE; KINESIN; KINESIN 12; KINESIN 5; UNCLASSIFIED DRUG;

ARTICLE; CELL NUCLEUS MEMBRANE; CENTROSOME; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; M PHASE CELL CYCLE CHECKPOINT; MOTOR ACTIVITY; PRIORITY JOURNAL; PROPHASE; PROTEIN FUNCTION;

BLOTTING, WESTERN; BONE NEOPLASMS; CENTROSOME; COLONY-FORMING UNITS ASSAY; DYNEINS; FLOW CYTOMETRY; HELA CELLS; HUMANS; KINESIN; MITOSIS; MITOTIC SPINDLE APPARATUS; NUCLEAR ENVELOPE; OSTEOSARCOMA; PROPHASE; RNA, SMALL INTERFERING;

EID: 84868537751     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2012.272     Document Type: Article

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