Effects of the iowa and milano mutations on apolipoprotein A-I structure and dynamics determined by hydrogen exchange and mass spectrometry

Biochemistry

Volumn 51, Issue 44, 2012, Pages 8993-9001

  Chetty, Palaniappan Sevugan ^a   Ohshiro, Maki ^c   Saito, Hiroyuki ^c   Dhanasekaran, Padmaja ^a   Lund Katz, Sissel ^a   Mayne, Leland ^b   Englander, Walter ^b   Phillips, Michael C ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN A-I; ARGININE RESIDUE; HELIX BUNDLE; HIGH-DENSITY LIPOPROTEINS; HYDROGEN EXCHANGE; HYDROGEN-DEUTERIUM EXCHANGE; IN-VIVO; INTERESTING POINTS; N-TERMINAL HELIX; NON-POLAR; PLASMA LEVELS; POINT MUTATIONS; STRUCTURAL EFFECT; STRUCTURE AND DYNAMICS; SYSTEMIC AMYLOIDOSIS; WILD TYPES;

AMIDES; DEUTERIUM; HYDROGEN; MASS SPECTROMETRY; STRUCTURAL DYNAMICS;

AMINO ACIDS;

APOLIPOPROTEIN A1; ARGININE; CYSTEINE; MUTANT PROTEIN;

ALPHA HELIX; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; DEUTERIUM HYDROGEN EXCHANGE; DIMERIZATION; IOWA MUTATION; MASS SPECTROMETRY; MILANO MUTATION; MOLECULAR DYNAMICS; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN MODIFICATION; PROTEIN STABILITY; PROTEIN STRUCTURE; WILD TYPE;

AMINO ACID SEQUENCE; APOLIPOPROTEIN A-I; DEUTERIUM EXCHANGE MEASUREMENT; HUMANS; HYDROGEN; MASS SPECTROMETRY; POINT MUTATION; PROTEIN STRUCTURE, SECONDARY;

EID: 84868537375     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi300926j     Document Type: Article

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