Local structure and global patterning of Cu2+ binding in fibrillar amyloid-β [Aβ(1-40)] Protein

Journal of the American Chemical Society

Volumn 134, Issue 44, 2012, Pages 18330-18337

  Gunderson, William A ^a   Hernández Guzmán, Jessica ^a   Karr, Jesse W ^b   Sun, Li ^a   Szalai, Veronika A ^c   Warncke, Kurt ^a  

^a EMORY UNIVERSITY   (United States)

^b SIENA COLLEGE   (United States)

^c NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER'S DISEASE; COORDINATION CHANGE; COORDINATION GEOMETRY; COORDINATION STRUCTURES; COPPER IONS; ELECTRON CHARGE; FIBRIL AXIS; HIGH CONCENTRATION; HIGH RESOLUTION; LOCAL STRUCTURE; MULTI-ELECTRON; N-TERMINALS; PULSED ELECTRON; REACTIVE OXYGEN SPECIES; REDOX CYCLING; REDOX REACTIVITY; SHEET FIBRILS; SWITCHABLE;

AMINO ACIDS; ELECTRON SPIN RESONANCE SPECTROSCOPY; METAL IONS; PARAMAGNETISM; PROTEINS;

GLYCOPROTEINS;

AMYLOID BETA PROTEIN[1-40]; COPPER ION; HISTIDINE; REACTIVE OXYGEN METABOLITE;

ARTICLE; BETA SHEET; CHEMICAL BINDING; CHEMICAL STRUCTURE; ELECTRON; ELECTRON SPIN RESONANCE; FIBER; GEOMETRY; OXIDATION REDUCTION REACTION; SIMULATION;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; BINDING SITES; COPPER; ELECTRON SPIN RESONANCE SPECTROSCOPY; HISTIDINE; HUMANS; MODELS, MOLECULAR; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; REACTIVE OXYGEN SPECIES;

EID: 84868526152     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja306946q     Document Type: Article

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