Hepatitis B virus X protein targets Bcl-2 proteins to increase intracellular calcium, required for virus replication and cell death induction

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 45, 2012, Pages 18471-18476

  Geng, Xin ^a   Huang, Chenghao ^b   Qin, Yan ^a   McCombs, Janet E ^a   Yuan, Quan ^b   Harry, Brian L ^a   Palmer, Amy E ^a   Xia, Ning Shao ^b   Xue, Ding ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b XIAMEN UNIVERSITY   (China)

Author keywords

Apoptosis; Calcium signaling; Necrosis

Indexed keywords

CALCIUM; HEPATITIS B VIRUS X PROTEIN; PROTEIN BCL 2; PROTEIN BCL XL; VIRUS RNA;

ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CELL DEATH; CONTROLLED STUDY; CYTOSOL; GENE MUTATION; GENE SILENCING; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; LIVER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; RNA INTERFERENCE; VIRUS REPLICATION;

AMINO ACID MOTIFS; ANIMALS; BCL-X PROTEIN; CALCIUM; CELL DEATH; CYTOSOL; HEP G2 CELLS; HEPATITIS B VIRUS; HEPATOCYTES; HUMANS; INTRACELLULAR SPACE; MICE; MICE, INBRED BALB C; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-BCL-2; TRANS-ACTIVATORS; VIRUS REPLICATION;

HEPATITIS B VIRUS; MAMMALIA;

EID: 84868522496     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1204668109     Document Type: Article

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