T-5224, a selective inhibitor of c-Fos/activator protein-1, attenuates lipopolysaccharide-induced liver injury in mice

Biotechnology Letters

Volumn 34, Issue 12, 2012, Pages 2175-2182

  Izuta, Shinichiro ^a   Ueki, Masaaki ^a   Ueno, Masaki ^b   Nishina, Kahoru ^c   Shiozawa, Shunichi ^d   Maekawa, Nobuhiro ^c  

^a KOBE UNIVERSITY HOSPITAL   (Japan)

^b KAGAWA UNIVERSITY   (Japan)

^c KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d KYUSHU UNIVERSITY BEPPU HOSPITAL   (Japan)

Author keywords

Cytokine; Endotoxemia; High mobility group box 1; Liver injury; Transcription factor activator protein 1; Tumor necrosis factor alpha

Indexed keywords

ACTIVATOR PROTEIN-1; CYTOKINES; ENDOTOXEMIA; HIGH-MOBILITY GROUPS; LIVER INJURIES; TUMOR NECROSIS FACTOR-ALPHA;

AMINO ACIDS; BODY FLUIDS; GLYCOPROTEINS; MACROPHAGES; TISSUE; TRANSCRIPTION FACTORS;

MAMMALS;

3 (5 (4 (CYCLOPENTYLOXY) 2 HYDROXYBENZOYL) 2 ((3 HYDROXY 1,2 BENZISOXAZOL 6 YL)METHOXY)PHENYL)PROPIONIC ACID; 3-(5-(4-(CYCLOPENTYLOXY)-2-HYDROXYBENZOYL)-2-((3-HYDROXY-1,2-BENZISOXAZOL-6-YL)METHOXY)PHENYL)PROPIONIC ACID; BENZOPHENONE DERIVATIVE; CYTOKINE; ENZYME; GASTROINTESTINAL AGENT; ISOXAZOLE DERIVATIVE; LIPOPOLYSACCHARIDE;

ANIMAL; ANIMAL HEPATITIS; ARTICLE; BLOOD; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; DRUG EFFECT; LIVER; MOUSE; PATHOLOGY; SURVIVAL; TOXIC HEPATITIS;

ANIMALS; BENZOPHENONES; CYTOKINES; DISEASE MODELS, ANIMAL; DRUG-INDUCED LIVER INJURY; ENZYMES; GASTROINTESTINAL AGENTS; HEPATITIS, ANIMAL; ISOXAZOLES; LIPOPOLYSACCHARIDES; LIVER; MICE; SURVIVAL ANALYSIS;

MUS;

EID: 84868503027     PISSN: 01415492     EISSN: 15736776     Source Type: Journal    
DOI: 10.1007/s10529-012-1022-4     Document Type: Article

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