-
1
-
-
0031027531
-
Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R))
-
R.J. Kowalski, P. Giannakakou, and E. Hamel Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R)) J Biol Chem 272 1997 2534 2541
-
(1997)
J Biol Chem
, vol.272
, pp. 2534-2541
-
-
Kowalski, R.J.1
Giannakakou, P.2
Hamel, E.3
-
2
-
-
57149135866
-
Preclinical efficacy spectrum and pharmacokinetics of ixabepilone
-
F.Y. Lee, R. Smykla, K. Johnston, K. Menard, K. McGlinchey, and R.W. Peterson Preclinical efficacy spectrum and pharmacokinetics of ixabepilone Cancer Chemother Pharmacol 63 2009 201 212
-
(2009)
Cancer Chemother Pharmacol
, vol.63
, pp. 201-212
-
-
Lee, F.Y.1
Smykla, R.2
Johnston, K.3
Menard, K.4
McGlinchey, K.5
Peterson, R.W.6
-
3
-
-
0035976543
-
Hedgehog signaling: A tale of two lipids
-
P.W. Ingham Hedgehog signaling: a tale of two lipids Science 294 2001 1879 1881
-
(2001)
Science
, vol.294
, pp. 1879-1881
-
-
Ingham, P.W.1
-
4
-
-
77952898697
-
Context-dependent regulation of the GLI code in cancer by HEDGEHOG and non-HEDGEHOG signals
-
B. Stecca, and I.A.A. Ruiz Context-dependent regulation of the GLI code in cancer by HEDGEHOG and non-HEDGEHOG signals J Mol Cell Biol 2 2010 84 95
-
(2010)
J Mol Cell Biol
, vol.2
, pp. 84-95
-
-
Stecca, B.1
Ruiz, I.A.A.2
-
6
-
-
59449104701
-
Role of hedgehog signaling in ovarian cancer
-
R. Bhattacharya, J. Kwon, B. Ali, E. Wang, S. Patra, and V. Shridhar Role of hedgehog signaling in ovarian cancer Clin Cancer Res 14 2008 7659 7666
-
(2008)
Clin Cancer Res
, vol.14
, pp. 7659-7666
-
-
Bhattacharya, R.1
Kwon, J.2
Ali, B.3
Wang, E.4
Patra, S.5
Shridhar, V.6
-
7
-
-
33751337806
-
Hedgehog signal pathway is activated in ovarian carcinomas, correlating with cell proliferation: It's inhibition leads to growth suppression and apoptosis
-
X. Chen, A. Horiuchi, N. Kikuchi, R. Osada, J. Yoshida, and T. Shiozawa Hedgehog signal pathway is activated in ovarian carcinomas, correlating with cell proliferation: it's inhibition leads to growth suppression and apoptosis Cancer Sci 98 2007 68 76
-
(2007)
Cancer Sci
, vol.98
, pp. 68-76
-
-
Chen, X.1
Horiuchi, A.2
Kikuchi, N.3
Osada, R.4
Yoshida, J.5
Shiozawa, T.6
-
8
-
-
35148825636
-
Chemoresistance to paclitaxel induces epithelial-mesenchymal transition and enhances metastatic potential for epithelial ovarian carcinoma cells
-
H. Kajiyama, K. Shibata, M. Terauchi, M. Yamashita, K. Ino, and A. Nawa Chemoresistance to paclitaxel induces epithelial-mesenchymal transition and enhances metastatic potential for epithelial ovarian carcinoma cells Int J Oncol 31 2007 277 283
-
(2007)
Int J Oncol
, vol.31
, pp. 277-283
-
-
Kajiyama, H.1
Shibata, K.2
Terauchi, M.3
Yamashita, M.4
Ino, K.5
Nawa, A.6
-
9
-
-
69949124827
-
Disrupting Hedgehog may reverse advanced cancer, if only temporarily
-
Kean S. Medicine Disrupting Hedgehog may reverse advanced cancer, if only temporarily Science 325 2009 1188
-
(2009)
Science
, vol.325
, pp. 1188
-
-
Medicine, K.S.1
-
10
-
-
57749093352
-
Molecular mechanisms of patupilone resistance
-
S. Mozzetti, R. Iantomasi, I. De Maria, S. Prislei, M. Mariani, and A. Camperchioli Molecular mechanisms of patupilone resistance Cancer Res 68 2008 10197 10204
-
(2008)
Cancer Res
, vol.68
, pp. 10197-10204
-
-
Mozzetti, S.1
Iantomasi, R.2
De Maria, I.3
Prislei, S.4
Mariani, M.5
Camperchioli, A.6
-
11
-
-
10744229243
-
Bcl-2 down-regulation is a novel mechanism of paclitaxel resistance
-
C. Ferlini, G. Raspaglio, S. Mozzetti, M. Distefano, F. Filippetti, and E. Martinelli Bcl-2 down-regulation is a novel mechanism of paclitaxel resistance Mol Pharmacol 64 2003 51 58
-
(2003)
Mol Pharmacol
, vol.64
, pp. 51-58
-
-
Ferlini, C.1
Raspaglio, G.2
Mozzetti, S.3
Distefano, M.4
Filippetti, F.5
Martinelli, E.6
-
12
-
-
38349110847
-
From plasma membrane to cytoskeleton: A novel function for semaphorin 6A
-
S. Prislei, S. Mozzetti, F. Filippetti, M. De Donato, G. Raspaglio, and L. Cicchillitti From plasma membrane to cytoskeleton: a novel function for semaphorin 6A Mol Cancer Ther 7 2008 233 241
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 233-241
-
-
Prislei, S.1
Mozzetti, S.2
Filippetti, F.3
De Donato, M.4
Raspaglio, G.5
Cicchillitti, L.6
-
13
-
-
0032808138
-
Gli proteins encode context-dependent positive and negative functions: Implications for development and disease
-
A. Ruiz i Altaba Gli proteins encode context-dependent positive and negative functions: implications for development and disease Development 126 1999 3205 3216
-
(1999)
Development
, vol.126
, pp. 3205-3216
-
-
Ruiz, I.1
Altaba, A.2
-
14
-
-
38349049063
-
Hypoxia induces class III beta-tubulin gene expression by HIF-1alpha binding to its 3' flanking region
-
G. Raspaglio, F. Filippetti, S. Prislei, R. Penci, I. De Maria, and L. Cicchillitti Hypoxia induces class III beta-tubulin gene expression by HIF-1alpha binding to its 3' flanking region Gene 409 2008 100 108
-
(2008)
Gene
, vol.409
, pp. 100-108
-
-
Raspaglio, G.1
Filippetti, F.2
Prislei, S.3
Penci, R.4
De Maria, I.5
Cicchillitti, L.6
-
15
-
-
70949087325
-
Gli1 is a potential target for alleviating multidrug resistance of gliomas
-
D. Cui, Q. Xu, K. Wang, and X. Che Gli1 is a potential target for alleviating multidrug resistance of gliomas J Neurol Sci 288 2010 156 166
-
(2010)
J Neurol Sci
, vol.288
, pp. 156-166
-
-
Cui, D.1
Xu, Q.2
Wang, K.3
Che, X.4
-
16
-
-
72949103044
-
Small-molecule modulators of the Sonic Hedgehog signaling pathway
-
B.Z. Stanton, and L.F. Peng Small-molecule modulators of the Sonic Hedgehog signaling pathway Mol Biosyst 6 2010 44 54
-
(2010)
Mol Biosyst
, vol.6
, pp. 44-54
-
-
Stanton, B.Z.1
Peng, L.F.2
-
17
-
-
33744536299
-
Sonic hedgehog regulates Gli activator and repressor functions with spatial and temporal precision in the mid/hindbrain region
-
S. Blaess, J.D. Corrales, and A.L. Joyner Sonic hedgehog regulates Gli activator and repressor functions with spatial and temporal precision in the mid/hindbrain region Development 133 2006 1799 1809
-
(2006)
Development
, vol.133
, pp. 1799-1809
-
-
Blaess, S.1
Corrales, J.D.2
Joyner, A.L.3
-
18
-
-
77949876005
-
Epithelial-mesenchymal transition in ovarian cancer
-
D. Vergara, B. Merlot, J.P. Lucot, P. Collinet, D. Vinatier, and I. Fournier Epithelial-mesenchymal transition in ovarian cancer Cancer Lett 291 2010 59 66
-
(2010)
Cancer Lett
, vol.291
, pp. 59-66
-
-
Vergara, D.1
Merlot, B.2
Lucot, J.P.3
Collinet, P.4
Vinatier, D.5
Fournier, I.6
-
19
-
-
72949095668
-
Hypoxia induces a hedgehog response mediated by HIF-1alpha
-
M.F. Bijlsma, A.P. Groot, J.P. Oduro, R.J. Franken, S.H. Schoenmakers, and M.P. Peppelenbosch Hypoxia induces a hedgehog response mediated by HIF-1alpha J Cell Mol Med 13 2009 2053 2060
-
(2009)
J Cell Mol Med
, vol.13
, pp. 2053-2060
-
-
Bijlsma, M.F.1
Groot, A.P.2
Oduro, J.P.3
Franken, R.J.4
Schoenmakers, S.H.5
Peppelenbosch, M.P.6
-
20
-
-
79956219871
-
Hypoxia activates the hedgehog signaling pathway in a ligand-independent manner by upregulation of Smo transcription in pancreatic cancer
-
H. Onishi, M. Kai, S. Odate, H. Iwasaki, Y. Morifuji, and T. Ogino Hypoxia activates the hedgehog signaling pathway in a ligand-independent manner by upregulation of Smo transcription in pancreatic cancer Cancer Sci 102 2011 1144 1150
-
(2011)
Cancer Sci
, vol.102
, pp. 1144-1150
-
-
Onishi, H.1
Kai, M.2
Odate, S.3
Iwasaki, H.4
Morifuji, Y.5
Ogino, T.6
-
21
-
-
77954752064
-
Randomized phase III trial of ixabepilone plus capecitabine versus capecitabine in patients with metastatic breast cancer previously treated with an anthracycline and a taxane
-
J.A. Sparano, E. Vrdoljak, O. Rixe, B. Xu, A. Manikhas, and C. Medina Randomized phase III trial of ixabepilone plus capecitabine versus capecitabine in patients with metastatic breast cancer previously treated with an anthracycline and a taxane J Clin Oncol 28 2010 3256 3263
-
(2010)
J Clin Oncol
, vol.28
, pp. 3256-3263
-
-
Sparano, J.A.1
Vrdoljak, E.2
Rixe, O.3
Xu, B.4
Manikhas, A.5
Medina, C.6
-
22
-
-
84862510018
-
Novel drugs targeting microtubules: The role of epothilones
-
G. Ferrandina, M. Mariani, M. Andreoli, S. Shahabi, G. Scambia, and C. Ferlini Novel drugs targeting microtubules: the role of epothilones Curr Pharm Des 18 2012 2793 2803
-
(2012)
Curr Pharm des
, vol.18
, pp. 2793-2803
-
-
Ferrandina, G.1
Mariani, M.2
Andreoli, M.3
Shahabi, S.4
Scambia, G.5
Ferlini, C.6
-
23
-
-
33747827890
-
Hedgehog signal transduction: Signal integration and cross talk in development and cancer
-
N.A. Riobo, K. Lu, and C.P. Emerson Jr. Hedgehog signal transduction: signal integration and cross talk in development and cancer Cell Cycle 5 2006 1612 1615
-
(2006)
Cell Cycle
, vol.5
, pp. 1612-1615
-
-
Riobo, N.A.1
Lu, K.2
Emerson Jr., C.P.3
-
24
-
-
33751285537
-
Hedgehog: An attribute to tumor regrowth after chemoradiotherapy and a target to improve radiation response
-
J. Sims-Mourtada, J.G. Izzo, S. Apisarnthanarax, T.T. Wu, U. Malhotra, and R. Luthra Hedgehog: an attribute to tumor regrowth after chemoradiotherapy and a target to improve radiation response Clin Cancer Res 12 2006 6565 6572
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6565-6572
-
-
Sims-Mourtada, J.1
Izzo, J.G.2
Apisarnthanarax, S.3
Wu, T.T.4
Malhotra, U.5
Luthra, R.6
-
25
-
-
34548215791
-
Targeting the hedgehog pathway to mitigate treatment resistance
-
Y.J. Chen, J. Sims-Mourtada, J. Izzo, and K.S. Chao Targeting the hedgehog pathway to mitigate treatment resistance Cell Cycle 6 2007 1826 1830
-
(2007)
Cell Cycle
, vol.6
, pp. 1826-1830
-
-
Chen, Y.J.1
Sims-Mourtada, J.2
Izzo, J.3
Chao, K.S.4
-
26
-
-
82955237344
-
ABCG2 is a direct transcriptional target of hedgehog signaling and involved in stroma-induced drug tolerance in diffuse large B-cell lymphoma
-
R.R. Singh, K. Kunkalla, C. Qu, E. Schlette, S.S. Neelapu, and F. Samaniego ABCG2 is a direct transcriptional target of hedgehog signaling and involved in stroma-induced drug tolerance in diffuse large B-cell lymphoma Oncogene 30 2011 4874 4886
-
(2011)
Oncogene
, vol.30
, pp. 4874-4886
-
-
Singh, R.R.1
Kunkalla, K.2
Qu, C.3
Schlette, E.4
Neelapu, S.S.5
Samaniego, F.6
-
27
-
-
31544480393
-
Snail induction is an early response to Gli1 that determines the efficiency of epithelial transformation
-
X. Li, W. Deng, C.D. Nail, S.K. Bailey, M.H. Kraus, and J.M. Ruppert Snail induction is an early response to Gli1 that determines the efficiency of epithelial transformation Oncogene 25 2006 609 621
-
(2006)
Oncogene
, vol.25
, pp. 609-621
-
-
Li, X.1
Deng, W.2
Nail, C.D.3
Bailey, S.K.4
Kraus, M.H.5
Ruppert, J.M.6
-
28
-
-
53049097596
-
Hedgehog signaling, epithelial-to-mesenchymal transition and miRNA (review)
-
Y. Katoh, and M. Katoh Hedgehog signaling, epithelial-to-mesenchymal transition and miRNA (review) Int J Mol Med 22 2008 271 275
-
(2008)
Int J Mol Med
, vol.22
, pp. 271-275
-
-
Katoh, Y.1
Katoh, M.2
-
29
-
-
80053211466
-
Cisplatin treatment of primary and metastatic epithelial ovarian carcinomas generates residual cells with mesenchymal stem cell-like profile
-
A. Latifi, K. Abubaker, N. Castrechini, A.C. Ward, C. Liongue, and F. Dobill Cisplatin treatment of primary and metastatic epithelial ovarian carcinomas generates residual cells with mesenchymal stem cell-like profile J Cell Biochem 112 2011 2850 2864
-
(2011)
J Cell Biochem
, vol.112
, pp. 2850-2864
-
-
Latifi, A.1
Abubaker, K.2
Castrechini, N.3
Ward, A.C.4
Liongue, C.5
Dobill, F.6
-
30
-
-
53049108469
-
P70 S6 kinase promotes epithelial to mesenchymal transition through snail induction in ovarian cancer cells
-
Y.L. Pon, H.Y. Zhou, A.N. Cheung, H.Y. Ngan, and A.S. Wong p70 S6 kinase promotes epithelial to mesenchymal transition through snail induction in ovarian cancer cells Cancer Res 68 2008 6524 6532
-
(2008)
Cancer Res
, vol.68
, pp. 6524-6532
-
-
Pon, Y.L.1
Zhou, H.Y.2
Cheung, A.N.3
Ngan, H.Y.4
Wong, A.S.5
-
31
-
-
38549161093
-
Is class III beta-tubulin a predictive factor in patients receiving tubulin-binding agents
-
P. Seve, and C. Dumontet Is class III beta-tubulin a predictive factor in patients receiving tubulin-binding agents Lancet Oncol 9 2008 168 175
-
(2008)
Lancet Oncol
, vol.9
, pp. 168-175
-
-
Seve, P.1
Dumontet, C.2
-
32
-
-
33646717530
-
Class III beta-tubulin overexpression is a marker of poor clinical outcome in advanced ovarian cancer patients
-
G. Ferrandina, G.F. Zannoni, E. Martinelli, A. Paglia, V. Gallotta, and S. Mozzetti Class III beta-tubulin overexpression is a marker of poor clinical outcome in advanced ovarian cancer patients Clin Cancer Res 12 2006 2774 2779
-
(2006)
Clin Cancer Res
, vol.12
, pp. 2774-2779
-
-
Ferrandina, G.1
Zannoni, G.F.2
Martinelli, E.3
Paglia, A.4
Gallotta, V.5
Mozzetti, S.6
|