Riccardin D-26, a synthesized macrocyclic bisbibenzyl compound, inhibits human hepatocellular carcinoma growth through induction of apoptosis in p53-dependent way

Cancer Letters

Volumn 328, Issue 1, 2013, Pages 104-113

  Yue, Bin ^a   Zhang, Yu Sheng ^a   Xu, Hui Min ^b   Zhao, Cui Rong ^a   Li, Yuan Yuan ^a   Qin, Yi Zhuo ^a   Wang, Rui Qi ^a   Sun, Di ^a   Yuan, Yi ^a   Lou, Hong Xiang ^a   Qu, Xian Jun ^a  

^a SHANDONG UNIVERSITY   (China)

^b QINGDAO UNIVERSITY   (China)

Author keywords

Apoptosis; Hepatocellular carcinoma; Macrocyclic bisbibenzyls; P53 Dependent pathway; Synthesized Riccardin D

Indexed keywords

ANTINEOPLASTIC AGENT; BIBENZYL DERIVATIVE; CYCLIN DEPENDENT KINASE INHIBITOR 1; ETOPOSIDE; PROTEIN BAX; PROTEIN P53; RICCARDIN D 26; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CANCER SIZE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG SAFETY; DRUG STRUCTURE; FEMALE; G1 PHASE CELL CYCLE CHECKPOINT; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; FEMALE; HUMANS; LIVER NEOPLASMS; MACROCYCLIC COMPOUNDS; MICE; MICE, INBRED BALB C; PHENYL ETHERS; STILBENES; TUMOR SUPPRESSOR PROTEIN P53; XENOGRAFT MODEL ANTITUMOR ASSAYS;

MUS;

EID: 84868447062     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2012.09.002     Document Type: Article

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