-
1
-
-
4544327298
-
ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction; A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Revise the 1999 Guidelines for the Management of patients with acute myocardial infarction)
-
Antman EM, Anbe DT, Armstrong PW, et al. ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction; a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Revise the 1999 Guidelines for the Management of patients with acute myocardial infarction). J Am Coll Cardiol, 2004; 44: E1-E211.
-
(2004)
J Am Coll Cardiol
, vol.44
-
-
Antman, E.M.1
Anbe, D.T.2
Armstrong, P.W.3
-
2
-
-
34548545280
-
ACC/AHA 2007 guidelines for the management of patients with unstable angina/non ST-elevation myocardial infarction: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines
-
(Writing Committee to Revise the 2002 Guidelines for the Management of Patients with Unstable Angina/Non ST-Elevation Myocardial Infarction): Developed in collaboration with the American College of Emergency Physicians the Society for Cardiovascular Angiography and Interventions, and the Society of Thoracic Surgeons: Endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation and the Society for Academic Emergency Medicine
-
Anderson JL, Adams CD, Antman EM, et al. ACC/AHA 2007 guidelines for the management of patients with unstable angina/non ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines for the Management of Patients With Unstable Angina/Non ST-Elevation Myocardial Infarction): developed in collaboration with the American College of Emergency Physicians, the Society for Cardiovascular Angiography and Interventions, and the Society of Thoracic Surgeons: endorsed by the American Association of Cardiovascular and Pulmonary Rehabilitation and the Society for Academic Emergency Medicine. Circulation, 2007; 116: e148-e304.
-
(2007)
Circulation
, vol.116
-
-
Anderson, J.L.1
Adams, C.D.2
Antman, E.M.3
-
3
-
-
57349189353
-
Management of acute myocardial infarction in patients presenting with persistent ST-segment elevation: The Task Force on the Management of ST-Segment Elevation Acute Myocardial Infarction of the European Society of Cardiology
-
Van de Werf F, Bax J, Betriu A, et al. Management of acute myocardial infarction in patients presenting with persistent ST-segment elevation: the Task Force on the Management of ST-Segment Elevation Acute Myocardial Infarction of the European Society of Cardiology. Eur Heart J, 2008; 29: 2909-2945.
-
(2008)
Eur Heart J
, vol.29
, pp. 2909-2945
-
-
Van De Werf, F.1
Bax, J.2
Betriu, A.3
-
4
-
-
34547772153
-
Guidelines for the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes
-
Bassand JP, Hamm CW, Ardissino D, et al. Guidelines for the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes. Eur Heart J, 2007; 28: 1598-1660.
-
(2007)
Eur Heart J
, vol.28
, pp. 1598-1660
-
-
Bassand, J.P.1
Hamm, C.W.2
Ardissino, D.3
-
5
-
-
18044388905
-
Preclinical and clinical studies with selective reversible direct P2Y12 antagonists
-
van Giezen JJ, Humphries RG,. Preclinical and clinical studies with selective reversible direct P2Y12 antagonists. Semin Thromb Hemost, 2005; 31: 195-204.
-
(2005)
Semin Thromb Hemost
, vol.31
, pp. 195-204
-
-
Van Giezen, J.J.1
Humphries, R.G.2
-
6
-
-
77954468084
-
Pharmacokinetics, pharmacodynamics, tolerability and safety of single ascending doses of ticagrelor, a reversibly binding oral P2Y(12) receptor antagonist, in healthy subjects
-
Teng R, Butler K,. Pharmacokinetics, pharmacodynamics, tolerability and safety of single ascending doses of ticagrelor, a reversibly binding oral P2Y(12) receptor antagonist, in healthy subjects. Eur J Clin Pharmacol, 2010; 66: 487-496.
-
(2010)
Eur J Clin Pharmacol
, vol.66
, pp. 487-496
-
-
Teng, R.1
Butler, K.2
-
7
-
-
33646261670
-
Pharmacodynamics, pharmacokinetics, and safety of the oral reversible P2Y12 antagonist AZD6140 with aspirin in patients with atherosclerosis: A double-blind comparison to clopidogrel with aspirin
-
Husted S, Emanuelsson H, Heptinstall S, Sandset PM, Wickens M, Peters G,. Pharmacodynamics, pharmacokinetics, and safety of the oral reversible P2Y12 antagonist AZD6140 with aspirin in patients with atherosclerosis: a double-blind comparison to clopidogrel with aspirin. Eur Heart J, 2006; 27: 1038-1047.
-
(2006)
Eur Heart J
, vol.27
, pp. 1038-1047
-
-
Husted, S.1
Emanuelsson, H.2
Heptinstall, S.3
Sandset, P.M.4
Wickens, M.5
Peters, G.6
-
8
-
-
73949112820
-
Randomized double-blind assessment of the ONSET and OFFSET of the antiplatelet effects of ticagrelor versus clopidogrel in patients with stable coronary artery disease: The ONSET/OFFSET study
-
Gurbel PA, Bliden KP, Butler K, et al. Randomized double-blind assessment of the ONSET and OFFSET of the antiplatelet effects of ticagrelor versus clopidogrel in patients with stable coronary artery disease: the ONSET/OFFSET study. Circulation, 2009; 120: 2577-2585.
-
(2009)
Circulation
, vol.120
, pp. 2577-2585
-
-
Gurbel, P.A.1
Bliden, K.P.2
Butler, K.3
-
9
-
-
69249213604
-
Ticagrelor binds to human P2Y(12) independently from ADP but antagonizes ADP-induced receptor signaling and platelet aggregation
-
van Giezen JJ, Nilsson L, Berntsson P, et al. Ticagrelor binds to human P2Y(12) independently from ADP but antagonizes ADP-induced receptor signaling and platelet aggregation. J Thromb Haemost, 2009; 7: 1556-1565.
-
(2009)
J Thromb Haemost
, vol.7
, pp. 1556-1565
-
-
Van Giezen, J.J.1
Nilsson, L.2
Berntsson, P.3
-
10
-
-
67649356342
-
Direct oral P2Y12 receptor antagonist AZD6140 potently and reversibly binds to the rh-P2Y12 receptor expressed on CHO-K1 cells
-
(abst P207)
-
van Giezen JJJ, Berntsson P, Wissing BM,. Direct oral P2Y12 receptor antagonist AZD6140 potently and reversibly binds to the rh-P2Y12 receptor expressed on CHO-K1 cells. Arterioscler Thromb Vasc Biol, 2008; 28: e-72 (abst P207).
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
-
-
Van Giezen, J.J.J.1
Berntsson, P.2
Wissing, B.M.3
-
11
-
-
77955992168
-
Absorption, distribution, metabolism, and excretion of ticagrelor in healthy subjects
-
Teng R, Oliver S, Hayes MA, Butler K,. Absorption, distribution, metabolism, and excretion of ticagrelor in healthy subjects. Drug Metab Dispos, 2010; 38: 1514-1521.
-
(2010)
Drug Metab Dispos
, vol.38
, pp. 1514-1521
-
-
Teng, R.1
Oliver, S.2
Hayes, M.A.3
Butler, K.4
-
12
-
-
77953498801
-
Pharmacokinetics, pharmacodynamics, safety and tolerability of multiple ascending doses of ticagrelor in healthy volunteers
-
Butler K, Teng R,. Pharmacokinetics, pharmacodynamics, safety and tolerability of multiple ascending doses of ticagrelor in healthy volunteers. Br J Clin Pharmacol, 2010; 70: 65-77.
-
(2010)
Br J Clin Pharmacol
, vol.70
, pp. 65-77
-
-
Butler, K.1
Teng, R.2
-
13
-
-
35548995394
-
Safety, tolerability, and initial efficacy of AZD6140, the first reversible oral adenosine diphosphate receptor antagonist, compared with clopidogrel, in patients with non-ST-segment elevation acute coronary syndrome: Primary results of the DISPERSE-2 trial
-
Cannon CP, Husted S, Harrington RA, et al. Safety, tolerability, and initial efficacy of AZD6140, the first reversible oral adenosine diphosphate receptor antagonist, compared with clopidogrel, in patients with non-ST-segment elevation acute coronary syndrome: primary results of the DISPERSE-2 trial. J Am Coll Cardiol, 2007; 50: 1844-1851.
-
(2007)
J Am Coll Cardiol
, vol.50
, pp. 1844-1851
-
-
Cannon, C.P.1
Husted, S.2
Harrington, R.A.3
-
14
-
-
35548933800
-
Inhibition of platelet aggregation by AZD6140, a reversible oral P2Y12 receptor antagonist, compared with clopidogrel in patients with acute coronary syndromes
-
Storey RF, Husted S, Harrington RA, et al. Inhibition of platelet aggregation by AZD6140, a reversible oral P2Y12 receptor antagonist, compared with clopidogrel in patients with acute coronary syndromes. J Am Coll Cardiol, 2007; 50: 1852-1856.
-
(2007)
J Am Coll Cardiol
, vol.50
, pp. 1852-1856
-
-
Storey, R.F.1
Husted, S.2
Harrington, R.A.3
-
15
-
-
77958003916
-
Inhibitory effects of ticagrelor compared with clopidogrel on platelet function in patients with acute coronary syndromes: The PLATO (PLATelet inhibition and patient Outcomes) PLATELET Substudy
-
Storey RF, Angiolillo DJ, Patil SB, et al. Inhibitory effects of ticagrelor compared with clopidogrel on platelet function in patients with acute coronary syndromes: the PLATO (PLATelet inhibition and patient Outcomes) PLATELET Substudy. J Am Coll Cardiol, 2010; 56: 1456-1462.
-
(2010)
J Am Coll Cardiol
, vol.56
, pp. 1456-1462
-
-
Storey, R.F.1
Angiolillo, D.J.2
Patil, S.B.3
-
16
-
-
70149101223
-
Ticagrelor versus clopidogrel in patients with acute coronary syndromes
-
Wallentin L, Becker RC, Budaj A, et al. Ticagrelor versus clopidogrel in patients with acute coronary syndromes. N Engl J Med, 2009; 361: 1045-1057.
-
(2009)
N Engl J Med
, vol.361
, pp. 1045-1057
-
-
Wallentin, L.1
Becker, R.C.2
Budaj, A.3
-
17
-
-
77953201509
-
Anticoagulant therapy for percutaneous coronary intervention
-
Rao SV, Ohman EM,. Anticoagulant therapy for percutaneous coronary intervention. Circ Cardiovasc Interv, 2010; 3: 80-88.
-
(2010)
Circ Cardiovasc Interv
, vol.3
, pp. 80-88
-
-
Rao, S.V.1
Ohman, E.M.2
-
18
-
-
0018924505
-
Effect of heparin and heparin fractions on platelet aggregation
-
Salzman EW, Rosenberg RD, Smith MH, Lindon JN, Favreau L,. Effect of heparin and heparin fractions on platelet aggregation. J Clin Invest, 1980; 65: 64-73.
-
(1980)
J Clin Invest
, vol.65
, pp. 64-73
-
-
Salzman, E.W.1
Rosenberg, R.D.2
Smith, M.H.3
Lindon, J.N.4
Favreau, L.5
-
19
-
-
0015819385
-
The potentiation of platelet aggregation and adhesion by heparin in vitro and in vivo
-
Thomson C, Forbes CD, Prentice CR,. The potentiation of platelet aggregation and adhesion by heparin in vitro and in vivo. Clin Sci Mol Med, 1973; 45: 485-494.
-
(1973)
Clin Sci Mol Med
, vol.45
, pp. 485-494
-
-
Thomson, C.1
Forbes, C.D.2
Prentice, C.R.3
-
20
-
-
0015278353
-
The platelet aggregating effect of eight commercial heparins
-
Eika C,. The platelet aggregating effect of eight commercial heparins. Scand J Haematol, 1972; 9: 480-482.
-
(1972)
Scand J Haematol
, vol.9
, pp. 480-482
-
-
Eika, C.1
-
21
-
-
0036624483
-
Decreased platelet reactivity in blood anticoagulated with bivalirudin or enoxaparin compared with unfractionated heparin: Implications for coronary intervention
-
Aggarwal A, Sobel BE, Schneider DJ,. Decreased platelet reactivity in blood anticoagulated with bivalirudin or enoxaparin compared with unfractionated heparin: implications for coronary intervention. J Thromb Thrombolysis, 2002; 13: 161-165.
-
(2002)
J Thromb Thrombolysis
, vol.13
, pp. 161-165
-
-
Aggarwal, A.1
Sobel, B.E.2
Schneider, D.J.3
-
22
-
-
0030664732
-
Differential effects of anticoagulants on the activation of platelets ex vivo
-
Schneider DJ, Tracy PB, Mann KG, Sobel BE,. Differential effects of anticoagulants on the activation of platelets ex vivo. Circulation, 1997; 96: 2877-2883.
-
(1997)
Circulation
, vol.96
, pp. 2877-2883
-
-
Schneider, D.J.1
Tracy, P.B.2
Mann, K.G.3
Sobel, B.E.4
-
23
-
-
77955846807
-
Determination of ticagrelor and two metabolites in plasma samples by liquid chromatography and mass spectrometry
-
Sillen H, Cook M, Davis P,. Determination of ticagrelor and two metabolites in plasma samples by liquid chromatography and mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci, 2010; 878: 2299-2306.
-
(2010)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.878
, pp. 2299-2306
-
-
Sillen, H.1
Cook, M.2
Davis, P.3
-
25
-
-
84855931347
-
Evaluation and characterization of the ticagrelor effects on serum and urinary uric acid in healthy volunteers
-
Butler K, Teng R,. Evaluation and characterization of the ticagrelor effects on serum and urinary uric acid in healthy volunteers. Clin Pharmacol Ther, 2012; 91: 264-271.
-
(2012)
Clin Pharmacol Ther
, vol.91
, pp. 264-271
-
-
Butler, K.1
Teng, R.2
-
26
-
-
79955964309
-
Heparin promotes platelet responsiveness by potentiating alphaIIbbeta3-mediated outside-in signaling
-
Gao C, Boylan B, Fang J, Wilcox DA, Newman DK, Newman PJ,. Heparin promotes platelet responsiveness by potentiating alphaIIbbeta3-mediated outside-in signaling. Blood, 2011; 117: 4946-4952.
-
(2011)
Blood
, vol.117
, pp. 4946-4952
-
-
Gao, C.1
Boylan, B.2
Fang, J.3
Wilcox, D.A.4
Newman, D.K.5
Newman, P.J.6
-
27
-
-
0345487533
-
Platelet activation with unfractionated heparin at therapeutic concentrations and comparisons with a low-molecular-weight heparin and with a direct thrombin inhibitor
-
Xiao Z, Theroux P,. Platelet activation with unfractionated heparin at therapeutic concentrations and comparisons with a low-molecular-weight heparin and with a direct thrombin inhibitor. Circulation, 1998; 97: 251-256.
-
(1998)
Circulation
, vol.97
, pp. 251-256
-
-
Xiao, Z.1
Theroux, P.2
-
28
-
-
33646580358
-
Heparin resistance and increased platelet activation in coronary surgery patients treated with enoxaparin preoperatively
-
Pleym H, Videm V, Wahba A, et al. Heparin resistance and increased platelet activation in coronary surgery patients treated with enoxaparin preoperatively. Eur J Cardiothorac Surg, 2006; 29: 933-940.
-
(2006)
Eur J Cardiothorac Surg
, vol.29
, pp. 933-940
-
-
Pleym, H.1
Videm, V.2
Wahba, A.3
-
29
-
-
0022899526
-
Comparison of the effects of low molecular weight heparin and unfractionated heparin on activation of human platelets in vitro
-
Westwick J, Scully MF, Poll C, Kakkar VV,. Comparison of the effects of low molecular weight heparin and unfractionated heparin on activation of human platelets in vitro. Thromb Res, 1986; 42: 435-447.
-
(1986)
Thromb Res
, vol.42
, pp. 435-447
-
-
Westwick, J.1
Scully, M.F.2
Poll, C.3
Kakkar, V.V.4
-
30
-
-
0031007008
-
The platelet proaggregating and potentiating effects of unfractionated heparin, low molecular weight heparin and heparinoid in intensive care patients and healthy controls
-
Burgess JK, Chong BH,. The platelet proaggregating and potentiating effects of unfractionated heparin, low molecular weight heparin and heparinoid in intensive care patients and healthy controls. Eur J Haematol, 1997; 58: 279-285.
-
(1997)
Eur J Haematol
, vol.58
, pp. 279-285
-
-
Burgess, J.K.1
Chong, B.H.2
-
31
-
-
2942700120
-
Attenuation of platelet reactivity by enoxaparin compared with unfractionated heparin in patients undergoing haemodialysis
-
Aggarwal A, Whitaker DA, Rimmer JM, et al. Attenuation of platelet reactivity by enoxaparin compared with unfractionated heparin in patients undergoing haemodialysis. Nephrol Dial Transplant, 2004; 19: 1559-1563.
-
(2004)
Nephrol Dial Transplant
, vol.19
, pp. 1559-1563
-
-
Aggarwal, A.1
Whitaker, D.A.2
Rimmer, J.M.3
-
32
-
-
0038506232
-
A whole blood flow cytometric determination of platelet activation by unfractionated and low molecular weight heparin in vitro
-
Klein B, Faridi A, von Tempelhoff GF, Heilmann L, Mittermayer C, Rath W,. A whole blood flow cytometric determination of platelet activation by unfractionated and low molecular weight heparin in vitro. Thromb Res, 2002; 108: 291-296.
-
(2002)
Thromb Res
, vol.108
, pp. 291-296
-
-
Klein, B.1
Faridi, A.2
Von Tempelhoff, G.F.3
Heilmann, L.4
Mittermayer, C.5
Rath, W.6
-
33
-
-
0032807806
-
Prolonged heparin administration during clopidogrel treatment in healthy subjects
-
Caplain H, D'Honneur G, Cariou R,. Prolonged heparin administration during clopidogrel treatment in healthy subjects. Semin Thromb Hemost, 1999; 25 (Suppl 2): 61-64.
-
(1999)
Semin Thromb Hemost
, vol.25
, Issue.SUPPL. 2
, pp. 61-64
-
-
Caplain, H.1
D'Honneur, G.2
Cariou, R.3
-
35
-
-
0038291841
-
Clopidogrel and warfarin: Absence of interaction in patients receiving long-term anticoagulant therapy for non-valvular atrial fibrillation
-
Lidell C, Svedberg LE, Lindell P, Bandh S, Job B, Wallentin L,. Clopidogrel and warfarin: absence of interaction in patients receiving long-term anticoagulant therapy for non-valvular atrial fibrillation. Thromb Haemost, 2003; 89: 842-846.
-
(2003)
Thromb Haemost
, vol.89
, pp. 842-846
-
-
Lidell, C.1
Svedberg, L.E.2
Lindell, P.3
Bandh, S.4
Job, B.5
Wallentin, L.6
-
36
-
-
77952400164
-
Oral anticoagulation with coumarin derivatives and antiplatelet effects of clopidogrel
-
Sibbing D, von Beckerath N, Morath T, et al. Oral anticoagulation with coumarin derivatives and antiplatelet effects of clopidogrel. Eur Heart J, 2010; 31: 1205-1211.
-
(2010)
Eur Heart J
, vol.31
, pp. 1205-1211
-
-
Sibbing, D.1
Von Beckerath, N.2
Morath, T.3
-
37
-
-
0033678468
-
Identification and biological activity of the active metabolite of clopidogrel
-
Savi P, Pereillo JM, Uzabiaga MF, et al. Identification and biological activity of the active metabolite of clopidogrel. Thromb Haemost, 2000; 84: 891-896.
-
(2000)
Thromb Haemost
, vol.84
, pp. 891-896
-
-
Savi, P.1
Pereillo, J.M.2
Uzabiaga, M.F.3
-
38
-
-
36348943475
-
Common polymorphisms of CYP2C19 and CYP2C9 affect the pharmacokinetic and pharmacodynamic response to clopidogrel but not prasugrel
-
Brandt JT, Close SL, Iturria SJ, et al. Common polymorphisms of CYP2C19 and CYP2C9 affect the pharmacokinetic and pharmacodynamic response to clopidogrel but not prasugrel. J Thromb Haemost, 2007; 5: 2429-2436.
-
(2007)
J Thromb Haemost
, vol.5
, pp. 2429-2436
-
-
Brandt, J.T.1
Close, S.L.2
Iturria, S.J.3
-
39
-
-
57349097594
-
Pharmacogenetic differences between warfarin, acenocoumarol and phenprocoumon
-
Beinema M, Brouwers JR, Schalekamp T, Wilffert B,. Pharmacogenetic differences between warfarin, acenocoumarol and phenprocoumon. Thromb Haemost, 2008; 100: 1052-1057.
-
(2008)
Thromb Haemost
, vol.100
, pp. 1052-1057
-
-
Beinema, M.1
Brouwers, J.R.2
Schalekamp, T.3
Wilffert, B.4
-
40
-
-
2942562619
-
Identification of cytochromes P450 2C9 and 3A4 as the major catalysts of phenprocoumon hydroxylation in vitro
-
Ufer M, Svensson JO, Krausz KW, Gelboin HV, Rane A, Tybring G,. Identification of cytochromes P450 2C9 and 3A4 as the major catalysts of phenprocoumon hydroxylation in vitro. Eur J Clin Pharmacol, 2004; 60: 173-182.
-
(2004)
Eur J Clin Pharmacol
, vol.60
, pp. 173-182
-
-
Ufer, M.1
Svensson, J.O.2
Krausz, K.W.3
Gelboin, H.V.4
Rane, A.5
Tybring, G.6
-
41
-
-
46449103184
-
The biotransformation of prasugrel, a new thienopyridine prodrug, by the human carboxylesterases 1 and 2
-
Williams ET, Jones KO, Ponsler GD, et al. The biotransformation of prasugrel, a new thienopyridine prodrug, by the human carboxylesterases 1 and 2. Drug Metab Dispos, 2008; 36: 1227-1232.
-
(2008)
Drug Metab Dispos
, vol.36
, pp. 1227-1232
-
-
Williams, E.T.1
Jones, K.O.2
Ponsler, G.D.3
-
42
-
-
34247256797
-
Cytochrome P450 3A inhibition by ketoconazole affects prasugrel and clopidogrel pharmacokinetics and pharmacodynamics differently
-
Farid NA, Payne CD, Small DS, et al. Cytochrome P450 3A inhibition by ketoconazole affects prasugrel and clopidogrel pharmacokinetics and pharmacodynamics differently. Clin Pharmacol Ther, 2007; 81: 735-741.
-
(2007)
Clin Pharmacol Ther
, vol.81
, pp. 735-741
-
-
Farid, N.A.1
Payne, C.D.2
Small, D.S.3
-
43
-
-
78349232464
-
Effect of intrinsic and extrinsic factors on the clinical pharmacokinetics and pharmacodynamics of prasugrel
-
Small DS, Farid NA, Payne CD, et al. Effect of intrinsic and extrinsic factors on the clinical pharmacokinetics and pharmacodynamics of prasugrel. Clin Pharmacokinet, 2010; 49: 777-798.
-
(2010)
Clin Pharmacokinet
, vol.49
, pp. 777-798
-
-
Small, D.S.1
Farid, N.A.2
Payne, C.D.3
-
44
-
-
75749102996
-
Metabolism and disposition of the thienopyridine antiplatelet drugs ticlopidine, clopidogrel, and prasugrel in humans
-
Farid NA, Kurihara A, Wrighton SA,. Metabolism and disposition of the thienopyridine antiplatelet drugs ticlopidine, clopidogrel, and prasugrel in humans. J Clin Pharmacol, 2010; 50: 126-142.
-
(2010)
J Clin Pharmacol
, vol.50
, pp. 126-142
-
-
Farid, N.A.1
Kurihara, A.2
Wrighton, S.A.3
|