-
1
-
-
0027376439
-
Antisense oligonucleotides: Is the bullet really magical?
-
Stein C.A., Cheng Y.C. Antisense oligonucleotides Is the bullet really magical? Science. 261:1993;1004-1012.
-
(1993)
Science
, vol.261
, pp. 1004-1012
-
-
Stein, C.A.1
Cheng, Y.C.2
-
2
-
-
0030974489
-
Antisense oligodeoxyribonucleotides suppress hematologic cell growth through stepwise release of deoxyribonucleotides
-
Vaerman J.L., Moureau P., Deldime F., Lewalle P., Lammineur C., Morschhauser F., Martiat P. Antisense oligodeoxyribonucleotides suppress hematologic cell growth through stepwise release of deoxyribonucleotides. Blood. 90:1997;331-339.
-
(1997)
Blood
, vol.90
, pp. 331-339
-
-
Vaerman, J.L.1
Moureau, P.2
Deldime, F.3
Lewalle, P.4
Lammineur, C.5
Morschhauser, F.6
Martiat, P.7
-
3
-
-
0028062847
-
Inhibition of protein kinase C-α expression in mice after systemic administration of phosphorothioate antisense oligodeoxynucleotides
-
Dean N.M., McKay R. Inhibition of protein kinase C-α expression in mice after systemic administration of phosphorothioate antisense oligodeoxynucleotides. Proc Natl Acad Sci USA. 91:1994;11762-11766.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 11762-11766
-
-
Dean, N.M.1
McKay, R.2
-
4
-
-
0027070730
-
In vivo treatment of human leukemia in a scid mouse model with c-myb antisense oligodeoxynucleotides
-
Ratajczak M.Z., Kant J.A., Luger S.M., Hijiya N., Zhang J., Zon G., Gewirtz A.M. In vivo treatment of human leukemia in a scid mouse model with c-myb antisense oligodeoxynucleotides. Proc Natl Acad Sci USA. 89:1992;11823-11827.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 11823-11827
-
-
Ratajczak, M.Z.1
Kant, J.A.2
Luger, S.M.3
Hijiya, N.4
Zhang, J.5
Zon, G.6
Gewirtz, A.M.7
-
5
-
-
0028815149
-
Phosphorothioate oligodeoxynucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors, and remove it from low affinity binding sites on extracellular matrix
-
Guvakova M.A., Yakubov L.A., Vlodavsky I., Tonkinson J.L., Stein C.A. Phosphorothioate oligodeoxynucleotides bind to basic fibroblast growth factor, inhibit its binding to cell surface receptors, and remove it from low affinity binding sites on extracellular matrix. J Biol Chem. 270:1995;2620-2627.
-
(1995)
J Biol Chem
, vol.270
, pp. 2620-2627
-
-
Guvakova, M.A.1
Yakubov, L.A.2
Vlodavsky, I.3
Tonkinson, J.L.4
Stein, C.A.5
-
6
-
-
0000407290
-
Mechanism of oligonucleotide uptake by cells: Involvement of specific receptors?
-
Yakubov L.A., Deeva E.A., Zarytova V.F., Ivanova E.M., Ryte A.S., Yurchenko L.V., Vlassov V.V. Mechanism of oligonucleotide uptake by cells Involvement of specific receptors? Proc Natl Acad Sci USA. 86:1989;6454-6458.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 6454-6458
-
-
Yakubov, L.A.1
Deeva, E.A.2
Zarytova, V.F.3
Ivanova, E.M.4
Ryte, A.S.5
Yurchenko, L.V.6
Vlassov, V.V.7
-
7
-
-
0030975358
-
Mac-1 (CD11b/CD18) is a cell surface oligodeoxynucleotide binding protein
-
Benimetskaya L., Loike J.D., Khaled Z., Silverstein S.C., Cao L., Cai T.Q., Stein C.A. Mac-1 (CD11b/CD18) is a cell surface oligodeoxynucleotide binding protein. Nat Med. 3:1997;414-420.
-
(1997)
Nat Med
, vol.3
, pp. 414-420
-
-
Benimetskaya, L.1
Loike, J.D.2
Khaled, Z.3
Silverstein, S.C.4
Cao, L.5
Cai, T.Q.6
Stein, C.A.7
-
8
-
-
0030040435
-
Identification of two oligodeoxyribonucleotide binding proteins on plasma membranes of human cell lines
-
Yao G.Q., Corrias S., Cheng Y.C. Identification of two oligodeoxyribonucleotide binding proteins on plasma membranes of human cell lines. Biochem Pharmacol. 51:1996;431-436.
-
(1996)
Biochem Pharmacol
, vol.51
, pp. 431-436
-
-
Yao, G.Q.1
Corrias, S.2
Cheng, Y.C.3
-
9
-
-
0028956615
-
Binding, uptake, and intracellular trafficking of phosphorothioate-modified oligodeoxynucleotides
-
Beltinger C., Saragovi H.V., Smith R.M., LeSauteur L., Shah N., DeDionisio L., Christensen L., Raible A., Jarett L., Gewirtz A.M. Binding, uptake, and intracellular trafficking of phosphorothioate-modified oligodeoxynucleotides. J Clin Invest. 95:1995;1814-1823.
-
(1995)
J Clin Invest
, vol.95
, pp. 1814-1823
-
-
Beltinger, C.1
Saragovi, H.V.2
Smith, R.M.3
Lesauteur, L.4
Shah, N.5
DeDionisio, L.6
Christensen, L.7
Raible, A.8
Jarett, L.9
Gewirtz, A.M.10
-
10
-
-
0027092897
-
Cationic lipids enhance cellular uptake and activity of phosphorothioate antisense oligonucleotides
-
Bennett C.F., Chiang M.V., Chan H., Shoemaker J., Mirabelli C. Cationic lipids enhance cellular uptake and activity of phosphorothioate antisense oligonucleotides. Mol Pharmacol. 41:1992;1023-1033.
-
(1992)
Mol Pharmacol
, vol.41
, pp. 1023-1033
-
-
Bennett, C.F.1
Chiang, M.V.2
Chan, H.3
Shoemaker, J.4
Mirabelli, C.5
-
11
-
-
0030013694
-
Efficient transfer of genetic material into mammalian cells using Starburst polyamidoamine dendrimers
-
Kukowska-Latallo J.F., Bielinska A.J., Johnson J., Spindler R., Tomalia D.A., Baker J.R. Jr. Efficient transfer of genetic material into mammalian cells using Starburst polyamidoamine dendrimers. Proc Natl Acad Sci USA. 93:1996;4897-4902.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 4897-4902
-
-
Kukowska-Latallo, J.F.1
Bielinska, A.J.2
Johnson, J.3
Spindler, R.4
Tomalia, D.A.5
Baker J.R., Jr.6
-
12
-
-
0027161566
-
Dynamics of the internalization of phosphodiester oligodeoxynucleotides in HL60 cells
-
Stein C.A., Tonkinson J.L., Zhang L.M., Yakubov L., Gervasoni J., Taub R., Rotenberg S.A. Dynamics of the internalization of phosphodiester oligodeoxynucleotides in HL60 cells. Biochemistry. 32:1993;4855-4861.
-
(1993)
Biochemistry
, vol.32
, pp. 4855-4861
-
-
Stein, C.A.1
Tonkinson, J.L.2
Zhang, L.M.3
Yakubov, L.4
Gervasoni, J.5
Taub, R.6
Rotenberg, S.A.7
-
14
-
-
0027535742
-
Activation of the ζ isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate
-
Nakanishi H., Brewer K.A., Exton J.H. Activation of the ζ isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem. 268:1993;13-16.
-
(1993)
J Biol Chem
, vol.268
, pp. 13-16
-
-
Nakanishi, H.1
Brewer, K.A.2
Exton, J.H.3
-
15
-
-
0028114572
-
Patterns of intracellular compartmentalization, trafficking and acidification of 5′-fluorescein labeled phosphodiester and phosphorothioate oligodeoxynucleotides in HL60 cells
-
Tonkinson J.L., Stein C.A. Patterns of intracellular compartmentalization, trafficking and acidification of 5′-fluorescein labeled phosphodiester and phosphorothioate oligodeoxynucleotides in HL60 cells. Nucleic Acids Res. 22:1994;4268-4275.
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 4268-4275
-
-
Tonkinson, J.L.1
Stein, C.A.2
-
16
-
-
0028898620
-
Effects of apoprotein E on intracellular metabolism of model triglyceride-rich particles are distinct from effects on cell particle uptake
-
Schweigelshohn B., Presley J.F., Gorecki M., Vogel T., Carpentier Y.A., Maxfield F.R., Deckelbaum R.J. Effects of apoprotein E on intracellular metabolism of model triglyceride-rich particles are distinct from effects on cell particle uptake. J Biol Chem. 270:1995;1761-1769.
-
(1995)
J Biol Chem
, vol.270
, pp. 1761-1769
-
-
Schweigelshohn, B.1
Presley, J.F.2
Gorecki, M.3
Vogel, T.4
Carpentier, Y.A.5
Maxfield, F.R.6
Deckelbaum, R.J.7
-
17
-
-
0027157640
-
Selective inhibition of protein kinase C isozymes by the indolocarbazole Go 6976
-
Martiny-Baron G., Kazanietz M.G., Mischak H., Blumberg P.M., Kochs G., Hug H., Marme D., Schachtele C. Selective inhibition of protein kinase C isozymes by the indolocarbazole Go 6976. J Biol Chem. 268:1993;9194-9197.
-
(1993)
J Biol Chem
, vol.268
, pp. 9194-9197
-
-
Martiny-Baron, G.1
Kazanietz, M.G.2
Mischak, H.3
Blumberg, P.M.4
Kochs, G.5
Hug, H.6
Marme, D.7
Schachtele, C.8
-
18
-
-
0027510002
-
Inhibitors of protein kinase C. 3. Potent and highly selective bisindolylmaleimides by conformational restriction
-
Bit R.R., Davis P.D., Elliott L.H., Harris W., Hill C.H., Keech E., Kumar H., Lawton G., Maw A., Nixon J.S., Vesey D., Wadsworth J., Wilkinson S. Inhibitors of protein kinase C. 3. Potent and highly selective bisindolylmaleimides by conformational restriction. J Med Chem. 36:1993;21-29.
-
(1993)
J Med Chem
, vol.36
, pp. 21-29
-
-
Bit, R.R.1
Davis, P.D.2
Elliott, L.H.3
Harris, W.4
Hill, C.H.5
Keech, E.6
Kumar, H.7
Lawton, G.8
Maw, A.9
Nixon, J.S.10
Vesey, D.11
Wadsworth, J.12
Wilkinson, S.13
-
20
-
-
0027965006
-
Protein kinase C ζ isoform is critical for κb-dependent promoter activation by sphingomyelinase
-
Lozano J., Berra E., Municio M.M., Díaz-Meco M.T., Dominguez I., Sanz L., Moscat J. Protein kinase C ζ isoform is critical for κB-dependent promoter activation by sphingomyelinase. J Biol Chem. 269:1994;19200-19202.
-
(1994)
J Biol Chem
, vol.269
, pp. 19200-19202
-
-
Lozano, J.1
Berra, E.2
Municio, M.M.3
Díaz-Meco, M.T.4
Dominguez, I.5
Sanz, L.6
Moscat, J.7
-
21
-
-
0028321727
-
Wortmannin binds specifically to 1-phosphatidylinositol 3-kinase while inhibiting guanine nucleotide-binding protein-coupled receptor signaling in neutrophil leukocytes
-
Thelen M., Wymann M.P., Langen H. Wortmannin binds specifically to 1-phosphatidylinositol 3-kinase while inhibiting guanine nucleotide-binding protein-coupled receptor signaling in neutrophil leukocytes. Proc Natl Acad Sci USA. 91:1994;4960-4964.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 4960-4964
-
-
Thelen, M.1
Wymann, M.P.2
Langen, H.3
-
23
-
-
0028170210
-
A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)
-
Vlahos C.J., Matter W.F., Hui K.Y., Brown R.F. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J Biol Chem. 269:1994;5241-5248.
-
(1994)
J Biol Chem
, vol.269
, pp. 5241-5248
-
-
Vlahos, C.J.1
Matter, W.F.2
Hui, K.Y.3
Brown, R.F.4
-
25
-
-
0029617910
-
Evidence of a role for MEK and MAPK during signal transduction by protein kinase C ζ
-
Berra E., Díaz-Meco M.T., Lozano J., Frutos S., Municio M.M., Sanchez P., Sanz L., Moscat J. Evidence of a role for MEK and MAPK during signal transduction by protein kinase C ζ EMBO J. 14:1995;6157-6163.
-
(1995)
EMBO J
, vol.14
, pp. 6157-6163
-
-
Berra, E.1
Díaz-Meco, M.T.2
Lozano, J.3
Frutos, S.4
Municio, M.M.5
Sanchez, P.6
Sanz, L.7
Moscat, J.8
-
26
-
-
0001613219
-
Protein kinase C ζ subspecies from rat brain: Its structure, expression, and properties
-
Ono Y., Fuji T., Ogita K., Kikkawa U., Igarashi K., Nishizuka Y. Protein kinase C ζ subspecies from rat brain Its structure, expression, and properties . Proc Natl Acad Sci USA. 86:1989;3099-3103.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 3099-3103
-
-
Ono, Y.1
Fuji, T.2
Ogita, K.3
Kikkawa, U.4
Igarashi, K.5
Nishizuka, Y.6
-
27
-
-
0026672998
-
MAP kinases: Charting the regulatory pathways
-
Pelech S.L., Sanghera J.S. MAP kinases Charting the regulatory pathways . Science. 257:1992;1355-1356.
-
(1992)
Science
, vol.257
, pp. 1355-1356
-
-
Pelech, S.L.1
Sanghera, J.S.2
-
28
-
-
0026658539
-
Purification and characterization of the ζ isoform of protein kinase C from bovine kidney
-
Nakanishi H., Exton J.H. Purification and characterization of the ζ isoform of protein kinase C from bovine kidney. J Biol Chem. 267:1992;16347-16354.
-
(1992)
J Biol Chem
, vol.267
, pp. 16347-16354
-
-
Nakanishi, H.1
Exton, J.H.2
-
29
-
-
0029656248
-
Protein kinase C-ζ mediates NF-κB activation in human imunodeficiency virus-infected monocytes
-
Folgueira L., McElhinny J.R., Bren G.D., MacMorran W.S., Díaz-Meco M.T., Moscat J., Paya C.V. Protein kinase C-ζ mediates NF-κB activation in human imunodeficiency virus-infected monocytes. J Virol. 70:1996;223-231.
-
(1996)
J Virol
, vol.70
, pp. 223-231
-
-
Folgueira, L.1
McElhinny, J.R.2
Bren, G.D.3
MacMorran, W.S.4
Díaz-Meco, M.T.5
Moscat, J.6
Paya, C.V.7
-
30
-
-
0029098523
-
Overexpression of mammalian protein kinase C-ζ does not affect the growth characteristics of NIH 3T3 cells
-
Crespo P., Mischak H., Gutkind J.S. Overexpression of mammalian protein kinase C-ζ does not affect the growth characteristics of NIH 3T3 cells. Biochem Biophys Res Commun. 213:1995;266-272.
-
(1995)
Biochem Biophys Res Commun
, vol.213
, pp. 266-272
-
-
Crespo, P.1
Mischak, H.2
Gutkind, J.S.3
-
31
-
-
0027970755
-
Overexpression of protein kinase C-ζ stimulates leukemic cell differentiation
-
Ways D.K., Posekany K., deVente J., Garris T., Chen J., Hooker J., Qin W., Cook P., Fletcher D., Parker P. Overexpression of protein kinase C-ζ stimulates leukemic cell differentiation. Cell Growth Differ. 5:1994;1195-1203.
-
(1994)
Cell Growth Differ
, vol.5
, pp. 1195-1203
-
-
Ways, D.K.1
Posekany, K.2
DeVente, J.3
Garris, T.4
Chen, J.5
Hooker, J.6
Qin, W.7
Cook, P.8
Fletcher, D.9
Parker, P.10
-
32
-
-
0029143549
-
Physical association and functional relationship between protein kinase Cζ and the actin cytoskeleton
-
Gomez J., Martinez de Aragon A., Bonay P., Pitton C., Garcia A., Silva A., Fresno M., Alvarez F., Rebollo A. Physical association and functional relationship between protein kinase Cζ and the actin cytoskeleton. Eur J Immunol. 25:1995;2673-2678.
-
(1995)
Eur J Immunol
, vol.25
, pp. 2673-2678
-
-
Gomez, J.1
Martinez De Aragon, A.2
Bonay, P.3
Pitton, C.4
Garcia, A.5
Silva, A.6
Fresno, M.7
Alvarez, F.8
Rebollo, A.9
-
33
-
-
0030065968
-
Insulin leads to a parallel translocation of PI-3-kinase and protein kinase C ζ
-
Mosthaf L., Kellerer M., Muhlhofer A., Mushack J., Seffer E., Haring H.U. Insulin leads to a parallel translocation of PI-3-kinase and protein kinase C ζ Exp Clin Endocrinol Diabetes. 104:1996;19-24.
-
(1996)
Exp Clin Endocrinol Diabetes
, vol.104
, pp. 19-24
-
-
Mosthaf, L.1
Kellerer, M.2
Muhlhofer, A.3
Mushack, J.4
Seffer, E.5
Haring, H.U.6
-
34
-
-
0029811866
-
Association of phosphatidylinositol 3 kinase to protein kinase C ζ during interleukin-2 stimulation
-
Gomez J., Martinez C., Garcia A., Rebollo A. Association of phosphatidylinositol 3 kinase to protein kinase C ζ during interleukin-2 stimulation. Eur J Immunol. 26:1996;1781-1787.
-
(1996)
Eur J Immunol
, vol.26
, pp. 1781-1787
-
-
Gomez, J.1
Martinez, C.2
Garcia, A.3
Rebollo, A.4
-
35
-
-
0028979563
-
Phosphatidylinositol 3-kinase regulation of fluid phase endocytosis
-
Clague M.J., Thorpe C., Jones A.T. Phosphatidylinositol 3-kinase regulation of fluid phase endocytosis. FEBS Lett. 367:1995;272-274.
-
(1995)
FEBS Lett
, vol.367
, pp. 272-274
-
-
Clague, M.J.1
Thorpe, C.2
Jones, A.T.3
-
36
-
-
0028786852
-
Evidence for phosphatidylinositol 3-kinase as a regulator of endocytosis via activation of Rab-5
-
Li G., D'Souza-Schorey C., Barbieri M.A., Roberts R.L., Klippel A., Williams L.T., Stahl P. Evidence for phosphatidylinositol 3-kinase as a regulator of endocytosis via activation of Rab-5. Proc Natl Acad Sci USA. 92:1995;10207-10211.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 10207-10211
-
-
Li, G.1
D'Souza-Schorey, C.2
Barbieri, M.A.3
Roberts, R.L.4
Klippel, A.5
Williams, L.T.6
Stahl, P.7
-
37
-
-
15844427939
-
Wortmannin-sensitive trafficking pathways in Chinese hamster ovary cells. Differential effects on endocytosis and lysosomal sorting
-
Martys J.L., Wjasow C., Gangi D.M., Kielian M.C., McGraw T.E., Backer J.M. Wortmannin-sensitive trafficking pathways in Chinese hamster ovary cells. Differential effects on endocytosis and lysosomal sorting. J Biol Chem. 271:1996;10953-10962.
-
(1996)
J Biol Chem
, vol.271
, pp. 10953-10962
-
-
Martys, J.L.1
Wjasow, C.2
Gangi, D.M.3
Kielian, M.C.4
McGraw, T.E.5
Backer, J.M.6
-
38
-
-
0029058288
-
Phosphatidylinositol 3-kinase activity is required at a postendocytic step in platelet-derived growth factor receptor trafficking
-
Joly M., Kazlauskas A., Corvera S. Phosphatidylinositol 3-kinase activity is required at a postendocytic step in platelet-derived growth factor receptor trafficking. J Biol Chem. 270:1995;13225-13230.
-
(1995)
J Biol Chem
, vol.270
, pp. 13225-13230
-
-
Joly, M.1
Kazlauskas, A.2
Corvera, S.3
-
39
-
-
0028351218
-
Disruption of PDGF receptor trafficking by mutation of its PI-3 kinase binding sites
-
Joly M., Kazlauskas A., Fay F.S., Corvera S. Disruption of PDGF receptor trafficking by mutation of its PI-3 kinase binding sites. Science. 263:1994;684-686.
-
(1994)
Science
, vol.263
, pp. 684-686
-
-
Joly, M.1
Kazlauskas, A.2
Fay, F.S.3
Corvera, S.4
-
40
-
-
0030987371
-
Cell surface perturbations of the epidermal growth factor and vascular endothelial growth factor receptors by phosphorothioate oligodeoxynucleotides
-
Rockwell P., O'Connor W.J., King K., Goldstein N.I., Zhang L.M., Stein C.A. Cell surface perturbations of the epidermal growth factor and vascular endothelial growth factor receptors by phosphorothioate oligodeoxynucleotides. Proc Natl Acad Sci USA. 94:1997;6523-6528.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 6523-6528
-
-
Rockwell, P.1
O'Connor, W.J.2
King, K.3
Goldstein, N.I.4
Zhang, L.M.5
Stein, C.A.6
-
41
-
-
0030584097
-
Protein kinase C and its substrates
-
Liu J.P. Protein kinase C and its substrates. Mol Cell Endocrinol. 116:1996;1-29.
-
(1996)
Mol Cell Endocrinol
, vol.116
, pp. 1-29
-
-
Liu, J.P.1
-
42
-
-
0027431089
-
Molecular cloning and characterization of PKCτ, an atypical isoform of protein kinase C derived from insulin-secreting cells
-
Selbie L.A., Schmitz-Peiffer C., Sheng Y., Biden T.J. Molecular cloning and characterization of PKCτ, an atypical isoform of protein kinase C derived from insulin-secreting cells. J Biol Chem. 268:1993;24296-24302.
-
(1993)
J Biol Chem
, vol.268
, pp. 24296-24302
-
-
Selbie, L.A.1
Schmitz-Peiffer, C.2
Sheng, Y.3
Biden, T.J.4
-
43
-
-
0002154224
-
Lipid metabolism in parenteral nutrition
-
J.L. Rombeau, & M.D. Caldwell. Philadelphia: W. B. Saunders
-
Carpentier Y., Van Gossu A., Dubois D.Y., Deckelbaum R.J. Lipid metabolism in parenteral nutrition. Rombeau J.L., Caldwell M.D. Clinical Nutrition Parenteral Nutrition . 1993;35-74 W. B. Saunders, Philadelphia.
-
(1993)
Clinical Nutrition: Parenteral Nutrition
, pp. 35-74
-
-
Carpentier, Y.1
Van Gossu, A.2
Dubois, D.Y.3
Deckelbaum, R.J.4
|