-
1
-
-
79959959354
-
The state of the art in anti-malarial drug discovery and development
-
10.2174/156802611795429194 21401508
-
The state of the art in anti-malarial drug discovery and development. Burrows JN, Chibale K, Wells TNC, Curr Top Med Chem 2011 11 1226 1254 10.2174/156802611795429194 21401508
-
(2011)
Curr Top Med Chem
, vol.11
, pp. 1226-1254
-
-
Burrows, J.N.1
Chibale, K.2
Wells, T.N.C.3
-
2
-
-
84856367163
-
Global phenotypic screening for antimalarials
-
10.1016/j.chembiol.2012.01.004 22284359
-
Global phenotypic screening for antimalarials. Guiguemde WA, Shelat AA, Garcia-Bustos JF, Diagana TT, Gamo FJ, Guy RK, Chem Biol 2012 19 116 129 10.1016/j.chembiol.2012.01.004 22284359
-
(2012)
Chem Biol
, vol.19
, pp. 116-129
-
-
Guiguemde, W.A.1
Shelat, A.A.2
Garcia-Bustos, J.F.3
Diagana, T.T.4
Gamo, F.J.5
Guy, R.K.6
-
4
-
-
84857591058
-
P.falciparum in vitro killing rates allow to discriminate between different antimalarial mode-of-action
-
10.1371/journal.pone.0030949 22383983
-
P.falciparum in vitro killing rates allow to discriminate between different antimalarial mode-of-action. Sanz LM, Crespo B, De-Cózar C, Ding XC, Llergo JL, Burrows JN, Garcia-Bustos JF, Gamo FJ, PLoS One 2012 7 30949 10.1371/journal.pone.0030949 22383983
-
(2012)
PLoS One
, vol.7
, pp. 530949
-
-
Sanz, L.M.1
Crespo, B.2
De-Cózar, C.3
Ding, X.C.4
Llergo, J.L.5
Burrows, J.N.6
Garcia-Bustos, J.F.7
Gamo, F.J.8
-
5
-
-
0023085302
-
Cytostatic effect of DL-α-difluoromethylornithine against Plasmodium falciparum and its reversal by diamines and spermidine
-
10.1007/BF00531084 3112767
-
Cytostatic effect of DL-α-difluoromethylornithine against Plasmodium falciparum and its reversal by diamines and spermidine. Assaraf YG, Golenser J, Spira DT, Messer G, Bachrach U, Parasitol Res 1987 73 313 318 10.1007/BF00531084 3112767
-
(1987)
Parasitol Res
, vol.73
, pp. 313-318
-
-
Assaraf, Y.G.1
Golenser, J.2
Spira, D.T.3
Messer, G.4
Bachrach, U.5
-
6
-
-
9444282112
-
Antiretrovirals as antimalarial agents
-
DOI 10.1086/425584
-
Antiretrovirals as antimalarial agents. Skinner-Adams TS, McCarthy JS, Gardiner DL, Hilton PM, Andrews KT, J Infect Dis 2004 190 1998 2000 10.1086/425584 15529265 (Pubitemid 39564706)
-
(2004)
Journal of Infectious Diseases
, vol.190
, Issue.11
, pp. 1998-2000
-
-
Skinner-Adams, T.S.1
McCarthy, J.S.2
Gardiner, D.L.3
Hilton, P.M.4
Andrews, K.T.5
-
7
-
-
0031019131
-
Characterization of the potent in vitro and in vivo antimalarial activities of ionophore compounds
-
Characterization of the potent in vitro and in vivo antimalarial activities of ionophore compounds. Gumila C, Ancelin M, Delort A, Jeminet G, Vial HJ, Antimicrob Agents Chemother 1997 41 523 529 9055986 (Pubitemid 27098397)
-
(1997)
Antimicrobial Agents and Chemotherapy
, vol.41
, Issue.3
, pp. 523-529
-
-
Gumila, C.1
Ancelin, M.-L.2
Delort, A.-M.3
Jeminet, G.4
Vial, H.J.5
-
8
-
-
0018704491
-
Synchronization of Plasmodium falciparum erythrocytic stages in culture
-
DOI 10.2307/3280287
-
Synchronization of Plasmodium falciparum erythrocytic stages in culture. Lambros C, Vanderberg JP, J Parasitol 1979 65 418 420 10.2307/3280287 383936 (Pubitemid 10222999)
-
(1979)
Journal of Parasitology
, vol.65
, Issue.3
, pp. 418-420
-
-
Lambros, C.1
Vanderberg, J.P.2
-
9
-
-
0027281689
-
Parasite lactate dehydrogenase as an assay for Plasmodium falciparum drug sensitivity
-
Parasite lactate dehydrogenase as an assay for Plasmodium falciparum drug sensitivity. Makler MT, Ries JM, Williams JA, Bancroft JE, Piper RC, Gibbins BL, Hinrichs DJ, AmJTrop Med Hyg 1993 48 739 741 (Pubitemid 23238452)
-
(1993)
American Journal of Tropical Medicine and Hygiene
, vol.48
, Issue.6
, pp. 739-741
-
-
Makler, M.T.1
Ries, J.M.2
Williams, J.A.3
Bancroft, J.E.4
Piper, R.C.5
Gibbins, B.L.6
Hinrichs, D.J.7
-
10
-
-
0036162628
-
Negative selection of Plasmodium falciparum reveals targeted gene deletion by double crossover recombination
-
DOI 10.1016/S0020-7519(01)00345-9, PII S0020751901003459
-
Negative selection of Plasmodium falciparum reveals targeted gene deletion by double crossover recombination. Duraisingh MT, Triglia T, Cowman AF, Int J Parasitol 2002 32 81 89 10.1016/S0020-7519(01)00345-9 11796125 (Pubitemid 34131595)
-
(2002)
International Journal for Parasitology
, vol.32
, Issue.1
, pp. 81-89
-
-
Duraisingh, M.T.1
Triglia, T.2
Cowman, A.F.3
-
11
-
-
0030885188
-
Transformation with human dihydrofolate reductase renders malaria parasites insensitive to WR99210 but does not affect the intrinsic activity of proguanil
-
DOI 10.1073/pnas.94.20.10931
-
Transformation with human dihydrofolate reductase renders malaria parasites insensitive to WR99210 but does not affect the intrinsic activity of proguanil. Fidock D, Wellems T, Proc Natl Acad Sci 1997 94 10931 10936 10.1073/pnas.94.20.10931 9380737 (Pubitemid 27430838)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.20
, pp. 10931-10936
-
-
Fidock, D.A.1
Wellems, T.E.2
-
12
-
-
33646264098
-
A comparison of assay performance measures in screening assays
-
10.1177/1087057105285610 16490779
-
A comparison of assay performance measures in screening assays. Iversen PW, Eastwood BJ, Sittampalam SG, Cox KL, J Biomol Screen 2006 11 247 252 10.1177/1087057105285610 16490779
-
(2006)
J Biomol Screen
, vol.11
, pp. 247-252
-
-
Iversen, P.W.1
Eastwood, B.J.2
Sittampalam, S.G.3
Cox, K.L.4
-
14
-
-
41549115882
-
Stage independent chloroquine resistance and chloroquine toxicity revealed via spinning disk confocal microscopy
-
DOI 10.1016/j.molbiopara.2007.12.014, PII S0166685107003465
-
Stage independent chloroquine resistance and chloroquine toxicity revealed via spinning disk confocal microscopy. Gligorijevic B, Purdy K, Elliot DA, Cooper RA, Roepe PD, Mol Biochem Parasitol 2008 159 7 23 10.1016/j.molbiopara.2007.12.014 18281110 (Pubitemid 351469918)
-
(2008)
Molecular and Biochemical Parasitology
, vol.159
, Issue.1
, pp. 7-23
-
-
Gligorijevic, B.1
Purdy, K.2
Elliott, D.A.3
Cooper, R.A.4
Roepe, P.D.5
-
15
-
-
84872543098
-
Insights into the role of heme in the mechanism of action of antimalarials
-
in press
-
Insights into the role of heme in the mechanism of action of antimalarials. Combrinck JM, Mabotha TE, Ncokazi KK, Ambele MA, Taylor D, Smith PJ, Hoppe HC, Egan TJ, ACS Chem Biol in press
-
ACS Chem Biol
-
-
Combrinck, J.M.1
Mabotha, T.E.2
Ncokazi, K.K.3
Ambele, M.A.4
Taylor, D.5
Smith, P.J.6
Hoppe, H.C.7
Egan, T.J.8
-
16
-
-
54049112217
-
Comprehensive study of proteasome inhibitors against Plasmodium falciparum laboratory strains and field isolates from Gabon
-
10.1186/1475-2875-7-187
-
Comprehensive study of proteasome inhibitors against Plasmodium falciparum laboratory strains and field isolates from Gabon. Kreidenweiss A, Kremsner PG, Mordmüller B, Malaria J 2008 7 187 10.1186/1475-2875-7-187
-
(2008)
Malaria J
, vol.7
, pp. 187
-
-
Kreidenweiss, A.1
Kremsner, P.G.2
Mordmüller, B.3
-
17
-
-
33646202766
-
A medicinal chemistry perspective on 4-aminoquinoline antimalarial drugs
-
10.2174/156802606776743147 16719804
-
A medicinal chemistry perspective on 4-aminoquinoline antimalarial drugs. O Neill PM, Ward SA, Berry NG, Jeyadevan JP, Biagini GA, Asadollaly E, Park BK, Bray PG, Curr Top Med Chem 2006 6 479 507 10.2174/156802606776743147 16719804
-
(2006)
Curr Top Med Chem
, vol.6
, pp. 479-507
-
-
Neill P M, O.1
Ward, S.A.2
Berry, N.G.3
Jeyadevan, J.P.4
Biagini, G.A.5
Asadollaly, E.6
Park, B.K.7
Bray, P.G.8
-
18
-
-
1542745991
-
A common mechanism for blockade of heme polymerization by antimalarial quinolines
-
DOI 10.1074/jbc.273.47.31103
-
A common mechanism for blockade of haem polymerization by antimalarial quinolines. Sullivan DJ, Matile H, Ridley RG, Goldberg DE, J Biol Chem 1998 273 31103 31107 10.1074/jbc.273.47.31103 9813011 (Pubitemid 28533119)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.47
, pp. 31103-31107
-
-
Sullivan Jr., D.J.1
Matile, H.2
Ridley, R.G.3
Goldberg, D.E.4
-
19
-
-
0036471447
-
Differential effects of 4-aminoquinoline-containing antimalarial drugs on hemoglobin digestion in Plasmodium falciparum-infected erythrocytes
-
DOI 10.1016/S0006-2952(01)00878-4, PII S0006295201008784
-
Differential effects of 4-aminoquinoline-containing antimalarial drugs on hemoglobin digestion in Plasmodium falciparum. Famin O, Ginsburg H, Biochem Pharmacol 2002 63 393 398 10.1016/S0006-2952(01)00878-4 11853690 (Pubitemid 34169719)
-
(2002)
Biochemical Pharmacology
, vol.63
, Issue.3
, pp. 393-398
-
-
Famin, O.1
Ginsburg, H.2
-
20
-
-
42949158177
-
Differential effects of quinoline antimalarials on endocytosis in Plasmodium falciparum
-
DOI 10.1128/AAC.01478-07
-
Differential effects of quinoline antimalarials on endocytosis in Plasmodium falciparum. Roberts L, Egan TJ, Joiner KA, Hoppe HC, Antimicrob Agents Chemother 2008 52 1840 1842 10.1128/AAC.01478-07 18316523 (Pubitemid 351614682)
-
(2008)
Antimicrobial Agents and Chemotherapy
, vol.52
, Issue.5
, pp. 1840-1842
-
-
Roberts, L.1
Egan, T.J.2
Joiner, K.A.3
Hoppe, H.C.4
-
21
-
-
77950362015
-
The Molecular Mechanism of Action of Artemisinin - The Debate Continues
-
The Molecular Mechanism of Action of Artemisinin-The Debate Continues. ONeill PM, Barton VE, Ward SA, Molecules 2010 15 1701 1721
-
(2010)
Molecules
, vol.15
, pp. 1701-1721
-
-
Oneill, P.M.1
Barton, V.E.2
Ward, S.A.3
-
22
-
-
31944440918
-
Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malaria
-
DOI 10.1128/AAC.50.2.639-648.2006
-
Potencies of human immunodeficiency virus protease inhibitors in vitro against Plasmodium falciparum and in vivo against murine malaria. Andrews KT, Fairlie DP, Madala PK, Ray J, Wyatt DM, Hilton PM, Melville LA, Beattie L, Gardiner DL, Reid RC, Stoermer MJ, Skinner-Adams T, Berry C, McCarthy JS, Antimicrob Agents Chemother 2006 50 639 648 10.1128/AAC.50.2.639-648.2006 16436721 (Pubitemid 43190977)
-
(2006)
Antimicrobial Agents and Chemotherapy
, vol.50
, Issue.2
, pp. 639-648
-
-
Andrews, K.T.1
Fairlie, D.P.2
Madala, P.K.3
Ray, J.4
Wyatt, D.M.5
Hilton, P.M.6
Melville, L.A.7
Beattie, L.8
Gardiner, D.L.9
Reid, R.C.10
Stoermer, M.J.11
Skinner-Adams, T.12
Berry, C.13
McCarthy, J.S.14
-
23
-
-
33846563919
-
Synergistic interactions of the antiretroviral protease inhibitors saquinavir and ritonavir with chloroquine and mefloquine against Plasmodium falciparum in vitro
-
DOI 10.1128/AAC.00840-06
-
Synergistic interactions of the antiretroviral protease inhibitors saquinavir and ritonavir with chloroquine and mefloquine against Plasmodium falciparum in vitro. Skinner-Adams TS, Andrews KT, Melville L, McCarthy J, Gardiner DL, Antimicrob Agents Chemother 2007 51 759 762 10.1128/AAC.00840-06 17088482 (Pubitemid 46185303)
-
(2007)
Antimicrobial Agents and Chemotherapy
, vol.51
, Issue.2
, pp. 759-762
-
-
Skinner-Adams, T.S.1
Andrews, K.T.2
Melville, L.3
McCarthy, J.4
Gardiner, D.L.5
-
24
-
-
0026754487
-
Model ion channels: Gramicidin and alamethicin
-
1279177
-
Model ion channels: gramicidin and alamethicin. Woolley GA, Wallace BA, J Membr Biol 1992 129 109 136 1279177
-
(1992)
J Membr Biol
, vol.129
, pp. 109-136
-
-
Woolley, G.A.1
Wallace, B.A.2
-
25
-
-
34249864120
-
A proteasome for all occasions
-
DOI 10.1016/j.febslet.2007.03.053, PII S0014579307003262, Vienna Special Issue: Molecular Machines
-
A proteasome for all occasions. Hanna J, Finley D, FEBS Lett 2007 581 2854 5861 10.1016/j.febslet.2007.03.053 17418826 (Pubitemid 46874384)
-
(2007)
FEBS Letters
, vol.581
, Issue.15
, pp. 2854-2861
-
-
Hanna, J.1
Finley, D.2
-
26
-
-
17144424622
-
Translational control in stress and apoptosis
-
DOI 10.1038/nrm1618
-
Translational control in stress and apoptosis. Holcik M, Sonenberg N, Nature Rev Cell Biol 2005 6 318 327 10.1038/nrm1618 (Pubitemid 40516898)
-
(2005)
Nature Reviews Molecular Cell Biology
, vol.6
, Issue.4
, pp. 318-327
-
-
Holcik, M.1
Sonenberg, N.2
-
27
-
-
70350238200
-
Luciferase protection against proteolytic degradation: A key for improving signal in nano-system biology
-
10.1016/j.jbiotec.2009.08.015 19732802
-
Luciferase protection against proteolytic degradation: a key for improving signal in nano-system biology. Ataei F, Hosseinkhani S, Khajeh K, J Biotechnol 2009 144 83 88 10.1016/j.jbiotec.2009.08.015 19732802
-
(2009)
J Biotechnol
, vol.144
, pp. 83-88
-
-
Ataei, F.1
Hosseinkhani, S.2
Khajeh, K.3
|