메뉴 건너뛰기




Volumn 62, Issue 11, 2012, Pages 735-741

Expression of EZH2 in renal cell carcinoma as a novel prognostic marker

Author keywords

Enhancer of zeste homolog 2; Immunohistochemistry; Kidney; Prognosis; Renal cell carcinoma

Indexed keywords

TRANSCRIPTION FACTOR EZH2;

EID: 84868316043     PISSN: 13205463     EISSN: 14401827     Source Type: Journal    
DOI: 10.1111/pin.12001     Document Type: Article
Times cited : (36)

References (33)
  • 1
    • 77952248366 scopus 로고    scopus 로고
    • Epidemiology and risk factors for kidney cancer
    • Chow WH, Dong LM, Devesa SS. Epidemiology and risk factors for kidney cancer. Nat Rev Urol 2010; 7: 245-57.
    • (2010) Nat Rev Urol , vol.7 , pp. 245-257
    • Chow, W.H.1    Dong, L.M.2    Devesa, S.S.3
  • 3
    • 0042821708 scopus 로고    scopus 로고
    • Prognostic factors in renal cell carcinoma
    • Kontak JA, Campbell SC. Prognostic factors in renal cell carcinoma. Urol Clin North Am 2003; 30: 467-80.
    • (2003) Urol Clin North Am , vol.30 , pp. 467-480
    • Kontak, J.A.1    Campbell, S.C.2
  • 4
    • 0034070298 scopus 로고    scopus 로고
    • The human EZH2 gene: Genomic organisation and revised mapping in 7q35 within the critical region for malignant myeloid disorders
    • Cardoso C, Mignon C, Hetet G, Grandchamps B, Fontes M, Colleaux L. The human EZH2 gene: Genomic organisation and revised mapping in 7q35 within the critical region for malignant myeloid disorders. Eur J Hum Genet 2000; 8: 174-80.
    • (2000) Eur J Hum Genet , vol.8 , pp. 174-180
    • Cardoso, C.1    Mignon, C.2    Hetet, G.3    Grandchamps, B.4    Fontes, M.5    Colleaux, L.6
  • 5
    • 0037423933 scopus 로고    scopus 로고
    • Polycomb, epigenomes, and control of cell identity
    • Orlando V. Polycomb, epigenomes, and control of cell identity. Cell 2003; 112: 599-606.
    • (2003) Cell , vol.112 , pp. 599-606
    • Orlando, V.1
  • 6
    • 77950602854 scopus 로고    scopus 로고
    • Histone deacetylase controls adult stem cell aging by balancing the expression of polycomb genes and jumonji domain containing 3
    • Jung JW, Lee S, Seo MS etal. Histone deacetylase controls adult stem cell aging by balancing the expression of polycomb genes and jumonji domain containing 3. Cell Mol Life Sci 2010; 67: 1165-76.
    • (2010) Cell Mol Life Sci , vol.67 , pp. 1165-1176
    • Jung, J.W.1    Lee, S.2    Seo, M.S.3
  • 7
    • 55949136562 scopus 로고    scopus 로고
    • Roles of the EZH2 histone methyltransferase in cancer epigenetics
    • Simon JA, Lange CA. Roles of the EZH2 histone methyltransferase in cancer epigenetics. Mutat Res 2008; 647: 21-9.
    • (2008) Mutat Res , vol.647 , pp. 21-29
    • Simon, J.A.1    Lange, C.A.2
  • 8
    • 17444379015 scopus 로고    scopus 로고
    • Deregulated expression of Polycomb-group oncogenes in human malignant lymphomas and epithelial tumors
    • Spec No 1
    • Raaphorst FM. Deregulated expression of Polycomb-group oncogenes in human malignant lymphomas and epithelial tumors. Hum Mol Genet 2005; 14: Spec No 1: R93-R100.
    • (2005) Hum Mol Genet , vol.14
    • Raaphorst, F.M.1
  • 9
    • 18644382388 scopus 로고    scopus 로고
    • The polycomb group protein EZH2 is involved in progression of prostate cancer
    • Varambally S, Dhanasekaran SM, Zhou M etal. The polycomb group protein EZH2 is involved in progression of prostate cancer. Nature 2002; 419: 624-9.
    • (2002) Nature , vol.419 , pp. 624-629
    • Varambally, S.1    Dhanasekaran, S.M.2    Zhou, M.3
  • 10
    • 0141816752 scopus 로고    scopus 로고
    • EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells
    • Kleer CG, Cao Q, Varambally S etal. EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells. Proc Natl Acad Sci U S A 2003; 100: 11606-11.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 11606-11611
    • Kleer, C.G.1    Cao, Q.2    Varambally, S.3
  • 12
  • 14
    • 84861112043 scopus 로고    scopus 로고
    • Systemic therapy in renal cell carcinoma: Advancing paradigms
    • Posadas EM, Figlin RA. Systemic therapy in renal cell carcinoma: Advancing paradigms. Oncology (Williston Park) 2012; 26: 290-301.
    • (2012) Oncology (Williston Park) , vol.26 , pp. 290-301
    • Posadas, E.M.1    Figlin, R.A.2
  • 15
    • 77954326508 scopus 로고    scopus 로고
    • Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
    • Suppl
    • Escudier B, Kataja V. Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 2010; 21 Suppl 5: v137-9.
    • (2010) Ann Oncol , vol.21 , Issue.5
    • Escudier, B.1    Kataja, V.2
  • 16
    • 35748937338 scopus 로고    scopus 로고
    • Integrative genomics analysis reveals silencing of beta-adrenergic signaling by polycomb in prostate cancer
    • Yu J, Cao Q, Mehra R etal. Integrative genomics analysis reveals silencing of beta-adrenergic signaling by polycomb in prostate cancer. Cancer Cell 2007; 12: 419-31.
    • (2007) Cancer Cell , vol.12 , pp. 419-431
    • Yu, J.1    Cao, Q.2    Mehra, R.3
  • 17
    • 78650412626 scopus 로고    scopus 로고
    • Epigenetic regulation of signaling pathways in cancer: Role of the histone methyltransferase EZH2
    • Tsang DP, Cheng AS. Epigenetic regulation of signaling pathways in cancer: Role of the histone methyltransferase EZH2. J Gastroenterol Hepatol 2011; 26: 19-27.
    • (2011) J Gastroenterol Hepatol , vol.26 , pp. 19-27
    • Tsang, D.P.1    Cheng, A.S.2
  • 18
    • 84856466661 scopus 로고    scopus 로고
    • The role of EZH2 in tumour progression
    • Chang CJ, Hung MC. The role of EZH2 in tumour progression. Br J Cancer 2012; 106: 243-7.
    • (2012) Br J Cancer , vol.106 , pp. 243-247
    • Chang, C.J.1    Hung, M.C.2
  • 19
    • 84859462010 scopus 로고    scopus 로고
    • ALDH1A1 is a novel EZH2 target gene in epithelial ovarian cancer identified by genome-wide approaches
    • Li H, Bitler BG, Vathipadiekal V etal. ALDH1A1 is a novel EZH2 target gene in epithelial ovarian cancer identified by genome-wide approaches. Cancer Prev Res (Phila) 2012; 5: 484-91.
    • (2012) Cancer Prev Res (Phila) , vol.5 , pp. 484-491
    • Li, H.1    Bitler, B.G.2    Vathipadiekal, V.3
  • 20
    • 50549103560 scopus 로고    scopus 로고
    • The enhancer of zeste homolog 2 gene contributes to cell proliferation and apoptosis resistance in renal cell carcinoma cells
    • Wagener N, Holland D, Bulkescher J etal. The enhancer of zeste homolog 2 gene contributes to cell proliferation and apoptosis resistance in renal cell carcinoma cells. Int J Cancer 2008; 123: 1545-50.
    • (2008) Int J Cancer , vol.123 , pp. 1545-1550
    • Wagener, N.1    Holland, D.2    Bulkescher, J.3
  • 21
    • 77957282672 scopus 로고    scopus 로고
    • Enhancer of zeste homolog 2 (EZH2) expression is an independent prognostic factor in renal cell carcinoma
    • Wagener N, Macher-Goeppinger S, Pritsch M etal. Enhancer of zeste homolog 2 (EZH2) expression is an independent prognostic factor in renal cell carcinoma. BMC Cancer 2010; 10: 524.
    • (2010) BMC Cancer , vol.10 , pp. 524
    • Wagener, N.1    Macher-Goeppinger, S.2    Pritsch, M.3
  • 22
    • 71849116150 scopus 로고    scopus 로고
    • Expression profile of the polycomb group protein enhancer of Zeste homologue 2 and its prognostic relevance in renal cell carcinoma
    • Hinz S, Weikert S, Magheli A etal. Expression profile of the polycomb group protein enhancer of Zeste homologue 2 and its prognostic relevance in renal cell carcinoma. J Urol 2009; 182: 2920-25.
    • (2009) J Urol , vol.182 , pp. 2920-2925
    • Hinz, S.1    Weikert, S.2    Magheli, A.3
  • 23
    • 33846817515 scopus 로고    scopus 로고
    • Identification of target antigens in specific immunotherapy for renal cell carcinoma
    • Komohara Y, Harada M, Arima Y etal. Identification of target antigens in specific immunotherapy for renal cell carcinoma. J Urol 2007; 177: 1157-62.
    • (2007) J Urol , vol.177 , pp. 1157-1162
    • Komohara, Y.1    Harada, M.2    Arima, Y.3
  • 24
    • 33645582536 scopus 로고    scopus 로고
    • Biomarker discovery in urogenital cancer
    • Suppl
    • Said J. Biomarker discovery in urogenital cancer. Biomarkers 2005; 10 Suppl 1: S83-6.
    • (2005) Biomarkers , vol.10 , Issue.1
    • Said, J.1
  • 25
    • 79958279832 scopus 로고    scopus 로고
    • p53-paralog DNp73 oncogene is repressed by IFNalpha/STAT2 through the recruitment of the Ezh2 polycomb group transcriptional repressor
    • Testoni B, Schinzari V, Guerrieri F, Gerbal-Chaloin S, Blandino G, Levrero M. p53-paralog DNp73 oncogene is repressed by IFNalpha/STAT2 through the recruitment of the Ezh2 polycomb group transcriptional repressor. Oncogene 2011; 30: 2670-8.
    • (2011) Oncogene , vol.30 , pp. 2670-2678
    • Testoni, B.1    Schinzari, V.2    Guerrieri, F.3    Gerbal-Chaloin, S.4    Blandino, G.5    Levrero, M.6
  • 26
    • 79959267832 scopus 로고    scopus 로고
    • Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker
    • Takawa M, Masuda K, Kunizaki M etal. Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker. Cancer Sci 2011; 102: 1298-305.
    • (2011) Cancer Sci , vol.102 , pp. 1298-1305
    • Takawa, M.1    Masuda, K.2    Kunizaki, M.3
  • 27
    • 79551541972 scopus 로고    scopus 로고
    • Down-regulation of miR-101 in endothelial cells promotes blood vessel formation through reduced repression of EZH2
    • Smits M, Mir SE, Nilsson RJ etal. Down-regulation of miR-101 in endothelial cells promotes blood vessel formation through reduced repression of EZH2. PLoS ONE 2011; 6: e16282.
    • (2011) PLoS ONE , vol.6
    • Smits, M.1    Mir, S.E.2    Nilsson, R.J.3
  • 28
    • 77955541508 scopus 로고    scopus 로고
    • Regulation of tumor angiogenesis by EZH2
    • Lu C, Han HD, Mangala LS etal. Regulation of tumor angiogenesis by EZH2. Cancer Cell 2010; 18: 185-97.
    • (2010) Cancer Cell , vol.18 , pp. 185-197
    • Lu, C.1    Han, H.D.2    Mangala, L.S.3
  • 29
    • 0142105414 scopus 로고    scopus 로고
    • EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer
    • Bracken AP, Pasini D, Capra M, Prosperini E, Colli E, Helin K. EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer. EMBO J 2003; 22: 5323-35.
    • (2003) EMBO J , vol.22 , pp. 5323-5335
    • Bracken, A.P.1    Pasini, D.2    Capra, M.3    Prosperini, E.4    Colli, E.5    Helin, K.6
  • 30
    • 84860255370 scopus 로고    scopus 로고
    • MicroRNA-26a regulates tumorigenic properties of EZH2 in human lung carcinoma cells
    • Dang X, Ma A, Yang L etal. MicroRNA-26a regulates tumorigenic properties of EZH2 in human lung carcinoma cells. Cancer Genet 2012; 205: 113-23.
    • (2012) Cancer Genet , vol.205 , pp. 113-123
    • Dang, X.1    Ma, A.2    Yang, L.3
  • 31
    • 58149239686 scopus 로고    scopus 로고
    • Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer
    • Varambally S, Cao Q, Mani RS etal. Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer. Science 2008; 322: 1695-9.
    • (2008) Science , vol.322 , pp. 1695-1699
    • Varambally, S.1    Cao, Q.2    Mani, R.S.3
  • 32
    • 80755144048 scopus 로고    scopus 로고
    • Decreased microRNA-214 levels in breast cancer cells coincides with increased cell proliferation, invasion and accumulation of the Polycomb Ezh2 methyltransferase
    • Derfoul A, Juan AH, Difilippantonio MJ, Palanisamy N, Ried T, Sartorelli V. Decreased microRNA-214 levels in breast cancer cells coincides with increased cell proliferation, invasion and accumulation of the Polycomb Ezh2 methyltransferase. Carcinogenesis 2011; 32: 1607-14.
    • (2011) Carcinogenesis , vol.32 , pp. 1607-1614
    • Derfoul, A.1    Juan, A.H.2    Difilippantonio, M.J.3    Palanisamy, N.4    Ried, T.5    Sartorelli, V.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.