-
2
-
-
24944526640
-
Converging on a general model of protein evolution
-
DOI 10.1016/j.tibtech.2005.07.009, PII S0167779905001988
-
Herbeck, J. T. & Wall, D. P. Converging on a general model of protein evolution. Trends Biotechnol 23, 485-7 (2005). (Pubitemid 41317910)
-
(2005)
Trends in Biotechnology
, vol.23
, Issue.10
, pp. 485-487
-
-
Herbeck, J.T.1
Wall, D.P.2
-
3
-
-
33745744354
-
Coping with the quantitative genomics 'elephant': The correlation between the gene dispensability and evolution rate
-
DOI 10.1016/j.tig.2006.04.009, PII S0168952506001363
-
Wolf, Y. I. Coping with the quantitative genomics 'elephant': The correlation between the gene dispensability and evolution rate. Trends Genet 22, 354-7 (2006). (Pubitemid 44015967)
-
(2006)
Trends in Genetics
, vol.22
, Issue.7
, pp. 354-357
-
-
Wolf, Y.I.1
-
4
-
-
33748980210
-
Evolutionary systems biology: Links between gene evolution and function
-
DOI 10.1016/j.copbio.2006.08.003, PII S0958166906001194, Systems Biology / Tissue and Cell Engineering
-
Koonin, E. V. & Wolf, Y. I. Evolutionary systems biology: links between gene evolution and function. Curr Opin Biotechnol 17, 481-7 (2006). (Pubitemid 44442925)
-
(2006)
Current Opinion in Biotechnology
, vol.17
, Issue.5
, pp. 481-487
-
-
Koonin, E.V.1
Wolf, Y.I.2
-
5
-
-
45449101500
-
Natural selection on genes that underlie human disease susceptibility
-
Blekhman, R. et al. Natural selection on genes that underlie human disease susceptibility. Curr Biol 18, 883-9 (2008).
-
(2008)
Curr Biol
, vol.18
, pp. 883-889
-
-
Blekhman, R.1
-
6
-
-
77952735087
-
Similarly strong purifying selection acts on human disease genes of all evolutionary ages
-
Cai, J. J., Borenstein, E., Chen, R. & Petrov, D. A. Similarly strong purifying selection acts on human disease genes of all evolutionary ages. Genome Biol Evol 1, 131-44 (2009).
-
(2009)
Genome Biol Evol
, vol.1
, pp. 131-144
-
-
Cai, J.J.1
Borenstein, E.2
Chen, R.3
Petrov, D.A.4
-
7
-
-
5444236355
-
Positive selection on the human genome
-
DOI 10.1093/hmg/ddh253
-
Vallender, E. J. & Lahn, B. T. Positive selection on the human genome. Hum Mol Genet 13 Spec No 2, R245-54 (2004). (Pubitemid 39359909)
-
(2004)
Human Molecular Genetics
, vol.13
, Issue.REV. ISSUE 2
-
-
Vallender, E.J.1
Lahn, B.T.2
-
8
-
-
33745121154
-
Positive natural selection in the human lineage
-
DOI 10.1126/science.1124309
-
Sabeti, P. C. et al. Positive natural selection in the human lineage. Science 312, 1614-20 (2006). (Pubitemid 43902654)
-
(2006)
Science
, vol.312
, Issue.5780
, pp. 1614-1620
-
-
Sabeti, P.C.1
Schaffner, S.F.2
Fry, B.3
Lohmueller, J.4
Varilly, P.5
Shamovsky, O.6
Palma, A.7
Mikkelsen, T.S.8
Altshuler, D.9
Lander, E.S.10
-
9
-
-
78650373804
-
Network medicine: A network-based approach to human disease
-
Barabasi, A. L., Gulbahce, N. & Loscalzo, J. Network medicine: a network-based approach to human disease. Nat Rev Genet 12, 56-68 (2011).
-
(2011)
Nat Rev Genet
, vol.12
, pp. 56-68
-
-
Barabasi, A.L.1
Gulbahce, N.2
Loscalzo, J.3
-
10
-
-
33947095027
-
A human phenome-interactome network of protein complexes implicated in genetic disorders
-
DOI 10.1038/nbt1295, PII NBT1295
-
Lage, K. et al. A human phenome-interactome network of protein complexes implicated in genetic disorders. Nat Biotechnol 25, 309-16 (2007). (Pubitemid 46402863)
-
(2007)
Nature Biotechnology
, vol.25
, Issue.3
, pp. 309-316
-
-
Lage, K.1
Karlberg, E.O.2
Storling, Z.M.3
Olason, P.I.4
Pedersen, A.G.5
Rigina, O.6
Hinsby, A.M.7
Tumer, Z.8
Pociot, F.9
Tommerup, N.10
Moreau, Y.11
Brunak, S.12
-
11
-
-
43249114206
-
Network-based global inference of human disease genes
-
Wu, X., Jiang, R., Zhang, M. Q. & Li, S. Network-based global inference of human disease genes. Mol Syst Biol 4, 189 (2008).
-
(2008)
Mol Syst Biol
, vol.4
, pp. 189
-
-
Wu, X.1
Jiang, R.2
Zhang, M.Q.3
Li, S.4
-
12
-
-
79957552475
-
Protein localization as a principal feature of the etiology and comorbidity of genetic diseases
-
Park, S. et al. Protein localization as a principal feature of the etiology and comorbidity of genetic diseases. Mol Syst Biol 7, 494 (2011).
-
(2011)
Mol Syst Biol
, vol.7
, pp. 494
-
-
Park, S.1
-
13
-
-
34547140875
-
The human disease network
-
Goh, K. I. et al. The human disease network. Proc Natl Acad Sci USA 104, 8685-90 (2007).
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 8685-8690
-
-
Goh, K.I.1
-
14
-
-
48249158278
-
The implications of human metabolic network topology for disease comorbidity
-
Lee, D. S. et al. The implications of human metabolic network topology for disease comorbidity. Proc Natl Acad Sci USA 105, 9880-5 (2008).
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 9880-9885
-
-
Lee, D.S.1
-
15
-
-
33746885883
-
Systemic determinants of gene evolution and function
-
Koonin, E. V. Systemic determinants of gene evolution and function. Mol Syst Biol 1, 2005 0021 (2005).
-
(2005)
Mol Syst Biol
, vol.1
, Issue.2005
, pp. 0021
-
-
Koonin, E.V.1
-
16
-
-
13444266370
-
Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders
-
DOI 10.1093/nar/gki033
-
Hamosh, A., Scott, A. F., Amberger, J. S., Bocchini, C. A. & McKusick, V. A. Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders. Nucleic Acids Res 33, D514-7 (2005). (Pubitemid 40207927)
-
(2005)
Nucleic Acids Research
, vol.33
-
-
Hamosh, A.1
Scott, A.F.2
Amberger, J.S.3
Bocchini, C.A.4
McKusick, V.A.5
-
17
-
-
77952208125
-
Contrasting genetic paths to morphological and physiological evolution
-
Liao, B. Y., Weng, M. P. & Zhang, J. Contrasting genetic paths to morphological and physiological evolution. Proc Natl Acad Sci USA 107, 7353-8 (2010).
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 7353-7358
-
-
Liao, B.Y.1
Weng, M.P.2
Zhang, J.3
-
18
-
-
78650680152
-
Characterization of the proteome, diseases and evolution of the human postsynaptic density
-
Bayes, A. et al. Characterization of the proteome, diseases and evolution of the human postsynaptic density. Nat Neurosci 14, 19-21 (2011).
-
(2011)
Nat Neurosci
, vol.14
, pp. 19-21
-
-
Bayes, A.1
-
19
-
-
80053215377
-
OrthoDisease: Tracking disease gene orthologs across 100 species
-
Forslund, K., Schreiber, F., Thanintorn, N. & Sonnhammer, E. L. OrthoDisease: tracking disease gene orthologs across 100 species. Brief Bioinform 12, 463-73 (2011).
-
(2011)
Brief Bioinform
, vol.12
, pp. 463-473
-
-
Forslund, K.1
Schreiber, F.2
Thanintorn, N.3
Sonnhammer, E.L.4
-
20
-
-
72849122933
-
From evolutionary genetics to human immunology: How selection shapes host defence genes
-
Barreiro, L. B. & Quintana-Murci, L. From evolutionary genetics to human immunology: how selection shapes host defence genes. Nat Rev Genet 11, 17-30 (2010).
-
(2010)
Nat Rev Genet
, vol.11
, pp. 17-30
-
-
Barreiro, L.B.1
Quintana-Murci, L.2
-
21
-
-
80053030747
-
Allergic asthma: Influence of genetic and environmental factors
-
Mukherjee, A. B. & Zhang, Z. Allergic asthma: influence of genetic and environmental factors. J Biol Chem 286, 32883-9 (2011).
-
(2011)
J Biol Chem
, vol.286
, pp. 32883-32889
-
-
Mukherjee, A.B.1
Zhang, Z.2
-
22
-
-
13444254254
-
The Mouse Genome Database (MGD): From genes to mice - A community resource for mouse biology
-
DOI 10.1093/nar/gki113
-
Eppig, J. T. et al. The Mouse Genome Database (MGD): from genes to mice-A community resource for mouse biology. Nucleic Acids Res 33, D471-5 (2005). (Pubitemid 40207917)
-
(2005)
Nucleic Acids Research
, vol.33
, Issue.DATABASE ISS.
-
-
Eppig, J.T.1
Bult, C.J.2
Kadin, J.A.3
Richardson, J.E.4
Blake, J.A.5
Anagnostopoulos, A.6
Baldarelli, R.M.7
Baya, M.8
Beal, J.S.9
Bello, S.M.10
Boddy, W.J.11
Bradt, D.W.12
Burkart, D.L.13
Butler, N.E.14
Campbell, J.15
Cassell, M.A.16
Corbani, L.E.17
Cousins, S.L.18
Dahmen, D.J.19
Dene, H.20
Diehl, A.D.21
Drabkin, H.J.22
Frazer, K.S.23
Frost, P.24
Glass, L.H.25
Goldsmith, C.W.26
Grant, P.L.27
Lennon-Pierce, M.28
Lewis, J.29
Lu, I.30
Maltais, L.J.31
McAndrews-Hill, M.32
McClellan, L.33
Miers, D.B.34
Miller, L.A.35
Ni, L.36
Ormsby, J.E.37
Qi, D.38
Reddy, T.B.K.39
Reed, D.J.40
Richards-Smith, B.41
Shaw, D.R.42
Sinclair, R.43
Smith, C.L.44
Szauter, P.45
Walker, M.B.46
Walton, D.O.47
Washburn, L.L.48
Witham, I.T.49
Zhu, Y.50
more..
-
23
-
-
0035166798
-
Acheiropodia is caused by a genomic deletion in C7orf2, the human orthologue of the Lmbr1 gene
-
DOI 10.1086/316955
-
Ianakiev, P. et al. Acheiropodia is caused by a genomic deletion in C7orf2, the human orthologue of the Lmbr1 gene. Am J Hum Genet 68, 38-45 (2001). (Pubitemid 32048360)
-
(2001)
American Journal of Human Genetics
, vol.68
, Issue.1
, pp. 38-45
-
-
Ianakiev, P.1
Van Baren, M.J.2
Daly, M.J.3
Toledo, S.P.A.4
Cavalcanti, M.G.5
Neto, J.C.6
Silveira, E.L.7
Freire-Maia, A.8
Heutink, P.9
Kilpatrick, M.W.10
Tsipouras, P.11
-
25
-
-
64349109427
-
The impact of cellular networks on disease comorbidity
-
Park, J., Lee, D. S., Christakis, N. A. & Barabasi, A. L. The impact of cellular networks on disease comorbidity. Mol Syst Biol 5, 262 (2009).
-
(2009)
Mol Syst Biol
, vol.5
, pp. 262
-
-
Park, J.1
Lee, D.S.2
Christakis, N.A.3
Barabasi, A.L.4
-
26
-
-
84864053752
-
Viral perturbations of host networks reflect disease etiology
-
Gulbahce, N. et al. Viral perturbations of host networks reflect disease etiology. PLoS Comput Biol 8, e1002531 (2012).
-
(2012)
PLoS Comput Biol
, vol.8
-
-
Gulbahce, N.1
-
27
-
-
66249129037
-
A dynamic network approach for the study of human phenotypes
-
Hidalgo, C. A., Blumm, N., Barabasi, A. L. & Christakis, N.A. A dynamic network approach for the study of human phenotypes. PLoS Comput Biol 5, e1000353 (2009).
-
(2009)
PLoS Comput Biol
, vol.5
-
-
Hidalgo, C.A.1
Blumm, N.2
Barabasi, A.L.3
Christakis, N.A.4
-
28
-
-
79955829987
-
Exploring the potential relevanceof human-specific genes to complex disease
-
Cooper, D.N. & Kehrer-Sawatzki, H.Exploring the potential relevanceof human-specific genes to complex disease. Hum Genomics 5, 99-107 (2011).
-
(2011)
Hum Genomics
, vol.5
, pp. 99-107
-
-
Cooper, D.N.1
Kehrer-Sawatzki, H.2
-
29
-
-
2442604715
-
The genetic association database
-
Becker, K. G., Barnes, K. C., Bright, T. J. & Wang, S. A. The genetic association database. Nat Genet 36, 431-2 (2004).
-
(2004)
Nat Genet
, vol.36
, pp. 431-432
-
-
Becker, K.G.1
Barnes, K.C.2
Bright, T.J.3
Wang, S.A.4
-
30
-
-
46749138206
-
Modularity in the genetic disease-phenotype network
-
Jiang, X. et al. Modularity in the genetic disease-phenotype network. FEBS Lett 582, 2549-54 (2008).
-
(2008)
FEBS Lett
, vol.582
, pp. 2549-2554
-
-
Jiang, X.1
-
31
-
-
80054976678
-
The evolution of gene expression levels in mammalian organs
-
Brawand, D. et al. The evolution of gene expression levels in mammalian organs. Nature 478, 343-8 (2011).
-
(2011)
Nature
, vol.478
, pp. 343-348
-
-
Brawand, D.1
-
32
-
-
79959898376
-
Prioritizing candidate disease genes by network-based boosting of genome-wide association data
-
Lee, I., Blom, U. M., Wang, P. I., Shim, J. E. & Marcotte, E. M. Prioritizing candidate disease genes by network-based boosting of genome-wide association data. Genome Res 21, 1109-21 (2011).
-
(2011)
Genome Res
, vol.21
, pp. 1109-1121
-
-
Lee, I.1
Blom, U.M.2
Wang, P.I.3
Shim, J.E.4
Marcotte, E.M.5
-
34
-
-
0018077606
-
Obtaining confidence intervals for the risk ratio in cohort studies
-
Katz, D., J, B., Azen, S. P. & M. C., P. Obtaining confidence interval for the risk ratio in cohort studies. Biometrics 34, 469-474 (1978). (Pubitemid 9016019)
-
(1978)
Biometrics
, vol.34
, Issue.3
, pp. 469-474
-
-
Katz, D.1
Baptista, J.2
Azen, S.P.3
Pike, M.C.4
-
35
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
Huang da, W., Sherman, B. T. & Lempicki, R. A. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4, 44-57 (2009).
-
(2009)
Nat Protoc
, vol.4
, pp. 44-57
-
-
Huang Da, W.1
Sherman, B.T.2
Lempicki, R.A.3
-
36
-
-
58549112996
-
Bioinformatics enrichment tools: Paths toward the comprehensive functional analysis of large gene lists
-
Huang da, W., Sherman, B. T. & Lempicki, R. A. Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res 37, 1-13 (2009).
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 1-13
-
-
Huang Da, W.1
Sherman, B.T.2
Lempicki, R.A.3
-
37
-
-
3242876302
-
Proteome Analyst: Custom predictions with explanations in a web-based tool for high-throughput proteome annotations
-
DOI 10.1093/nar/gkh485
-
Szafron, D. et al. Proteome Analyst: custom predictions with explanations in a web-based tool for high-throughput proteome annotations. Nucleic Acids Res 32, W365-71 (2004). (Pubitemid 38997360)
-
(2004)
Nucleic Acids Research
, vol.32
-
-
Szafron, D.1
Lu, P.2
Greiner, R.3
Wishart, D.S.4
Poulin, B.5
Eisner, R.6
Lu, Z.7
Anvik, J.8
Macdonell, C.9
Fyshe, A.10
Meeuwis, D.11
-
38
-
-
67650351540
-
Construction of functional interaction networks through consensus localization predictions of the human proteome
-
Park, S., Yang, J. S., Jang, S. K. & Kim, S. Construction of functional interaction networks through consensus localization predictions of the human proteome. J Proteome Res 8, 3367-76 (2009).
-
(2009)
J Proteome Res
, vol.8
, pp. 3367-3376
-
-
Park, S.1
Yang, J.S.2
Jang, S.K.3
Kim, S.4
|