Interstrain differences in the severity of liver injury induced by a choline- and folate-deficient diet in mice are associated with dysregulation of genes involved in lipid metabolism

FASEB Journal

Volumn 26, Issue 11, 2012, Pages 4592-4602

  Tryndyak, Volodymyr ^a   De Conti, Aline ^d   Kobets, Tetyana ^a,e   Kutanzi, Kristy ^a   Koturbash, Igor ^a   Han, Tao ^b   Fuscoe, James C ^b   Latendresse, John R ^c   Melnyk, Stepan ^f   Shymonyak, Svitlana ^e   Collins, Leonard ^e   Ross, Sharon A ^g   Rusyn, Ivan ^e   Beland, Frederick A ^a   Pogribny, Igor P ^a  

^a NCTR   (United States)

^b Division of Systems Biology   (United States)

^c NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^d UNIVERSITY OF SÃO PAULO   (Brazil)

^e University of North Carolina at Chapel Hill   (United States)

^f UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^g NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Interindividual; Nonalcoholic fatty liver; Oxidative stress

Indexed keywords

CHOLINE; FOLIC ACID; METHYL GROUP; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CATABOLISM; CONTROLLED STUDY; DIETARY INTAKE; DNA DAMAGE; DOWN REGULATION; FEEDING; LIPID METABOLISM; LIVER INJURY; MALE; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

ANIMAL FEED; ANIMALS; CHOLINE; CHOLINE DEFICIENCY; CYTOCHROME P-450 ENZYME SYSTEM; DIET; DNA DAMAGE; FATTY LIVER; FOLIC ACID; FOLIC ACID DEFICIENCY; GENE EXPRESSION REGULATION; GENETIC VARIATION; LIPID METABOLISM; MALE; MICE; MICE, INBRED STRAINS; OXIDATIVE STRESS; PROTEIN ARRAY ANALYSIS; TRANSCRIPTOME;

MUS;

EID: 84868277623     PISSN: None     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.12-209569     Document Type: Article

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