Antioxidant and anti-hyperglycemic potential of pulp extracts of Irvingia wombolu fruits

Biology and Medicine

Volumn 4, Issue 1, 2012, Pages 10-19

  Matsinkou, R S ^a   Ngondi, J L ^a   Kuate, D ^a,c   Mbofung, C ^b   Oben, J E ^a  

^a UNIVERSITY OF YAOUNDÉ I   (Cameroon)

^b UNIVERSITY OF NGAOUNDERE   (Cameroon)

^c UNIVERSITY OF DSCHANG   (Cameroon)

Author keywords

Diabetes; I. Wombolu; Irvingia wombolu; Oxidative stress; Plant extracts; Polyphenols

Indexed keywords

EID: 84868275485     PISSN: None     EISSN: 09748369     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Agbor L, 1994. Marketing trends and potentials for Irvingia gabonensis products in Nigeria. Proceedings of ICRAF-IITA Conference on Irvingia gabonensis, May 3-5, Ibadan, Nigeria.
2. Assmann G, 1979. Current diagnosis of hyperlipidemias. Internist (Berl), 20(11): 559-564.
3. Bailey CJ, Flatt PR, 1986. Animal models of diabetes. In: Nattras M. [Ed.], Recent Advances in Diabetes II. Churchill Livingstone, Edinburg, UK, 71-89.
4. Benzie IFF, Strain JJ, 1996. The Ferric Reducing Ability of Plasma (FRAP) as a measure of antioxidant power: The FRAP assay. Analytical Biochemistry. 239: 70-76.
5. Bhattaram VA, Ceraefe M, Kohlest C, Vest M, Deundorf H, 2002. Pharmacokinetics and bioavailability of herbal medicinal products. Phytomedicine, 9: 1-36.
6. Bopanna KN, Kannan J, Sushma G, Balaraman R, Rathod SP, 1997. Antidiabetic and antihyperlipidemic effect of neem seed kernel powder on alloxan diabetic rabbits. Indian Journal of Pharmacology, 29: 162-167.
7. Brand-Williams W, Cuvelier ME, Berset C, 1995. Use of a free radical method to evaluate antioxidant activity. Lebensmittel-Wissenschaft und-Technologie, 28: 25-30.
8. Denis TCP, Madeira VMC, Almeida MLM, 1994. Action of phenolic derivates (acetaminophane, salycilate, and 5-aminosalycilate) as inhibitors of membrane lipid peroxydation and as peroxyl radical scavengers. Archives of Biochemistry and Biophysics, 40: 945-948.
9. Ejiofor MAN, Onwubuke SN, Okafor JC, 1987. Developing improved methods of processing and utilization of kernels of Irvingia gabonensis (var. gabonensis and var. excelsa). The International Tree Crops Journal, 4: 283-290.
10. Evans JL, Goldfine ID, Maddux BA, Grodsky GM, 2002. Oxidative stress and stress-activated signalling pathways: A unifying hypothesis of type 2 diabetes. Endocrine Reviews, 23(5): 599-622.
11. Fuhrman B, Aviram M, 2001. Flavonoids protect LDL from oxidation and attenuate atherosclerosis. Current Opinion in Lipidology, 12: 41-48.
12. Gülcin I, Beydemir S, Alici HA, Elmastas M, Büyükokuroglu ME, 2004. In vitro antioxidant properties of morphine. Pharmacogical Research, 49: 59-66.
13. Halliwell B, 1991. Reactive oxygen species in living systems: source, biochemistry, and role in human disease. American Journal of Medicine, 91(3C): 14S-22S.
14. Halliwell B, Gutteridge JM, Aruoma OI, 1987. The deoxyribose method: a simple "test-tube" assay for determination of rate constants for reactions of hydroxyl radicals. Analytical Biochemistry, 165: 215-219.
15. Hou Z, Zhang Z, Wu H, 2005. Effect of Sanguis draxonis (a Chinese traditional herb) on the formation of insulin resistance in rats. Diabetes Research and Clinical Practice, 68: 3-11.
16. Jacobs NJ, Vandemark PJ, 1975. The purification and properties of the alpha-glycerophosphate-oxidizing enzyme of Streptococcus faecalis 10C1. Archives of Biochemistry and Biophysics, 88: 250-255.
17. Junod A, Lambert AE, Stauffacher W, Renold AE, 1969. Diabetogenic action of streptozotocin: Relationship of dose to metabolic response. Journal of Clinical Investigation, 48: 2129-2139.
18. Katalinié V, Milos M, Musi I, Boban M, 2004. Antioxidant effectiveness of selected wines in comparison with (+)-catechin. Food Chemistry, 86: 593-600.
19. Loew D, Kaszkin M, 2002. Approaching the problem of bioequivalence of herbal medicinal products. Phytotherapy Research, 16: 705-711.
20. Lyra R, Oliveira M, Lins D, Cavalcanti N, 2006. Prevention of type 2 diabetes mellitus. Arq. Bras. Endocrinology and Metabolism, 50: 239-249.
21. Mahinda W, Shahidi F, 2000. Scavenging of reactive-oxygen species and DPPH free radicals by extracts of borage and evening primrose meals. Food Chemistry, 70: 17-26.
22. Marshal JW, Bangert SK, 2004. In: Clinical Chemistry: Disorders of carbohydrates metabolism, 5th Edn.. Elsevier Limited, 191-217.
23. Ngondi JL, Fossouo Z, Djiotsa EJ, Oben J, 2006. Glycaemic variations after administration of Irvingia gabonensis seeds fractions in normoglycemic rats. African Journal of Traditional Complementary and. Alternative Medicines, 4: 94-110.
24. Oviasogie PO, Okoro D, Ndiokwere CL, 2009. Determination of total phenolic amount of some edible fruits and vegetables. African Journal of Biotechnology, 8 (12): 2819-2820.
25. Rahman MM, Grover MF, 2005. Serum lipid peroxydation and antioxidant enzyme levels in male and female diabetic patients. Singapore Medicinal Journal. 46 (7): 322.
26. Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans CA, 1999. Antioxidant activity applying an improved ABTS radical cation decolourization assay. Free Radical Biology and Medicine, 26 (9-10): 1231-1237.
27. Retnam VJ, Nerurkar SV, Gupta MH, Bhandarkar SD, Taskar SP, 1983. Plasma lipids and lipoproteins in treated diabetics. Journal of Postgraduate Medicine, 29: 193-200.
28. Richmond W, 1973. Preparation and properties of a cholesterol oxidase from Nocardia sp. and its application to the enzymatic assay of total cholesterol in serum, Clinical Chemistry, 19: 476-482.
29. Robertson RP, 2004. Chronic oxidative stress as a central mechanism for glucose toxicity in pancreatic islet beta cells in diabetes. The Journal of Biological Chemistry, 279 (41): 42351-42354.
30. Shih KC, Kwak CF, Hwa CM, 1997. Acipimox attenuates hypertriglyceredemia in dislipidemic non-insulin dependent diabetes mellitus patients without perturbation of insulin sensitivity and glycemic control. Diabetes Research and Clinical Practice, 36 (2): 113-119.
31. Singleton VL, Orthofer R, Lamuela-Raventòs RM, 1999. Analysis of total phenols and other oxidation substrates and other oxidation substrates and antioxidants by means of Folin-Ciocalteu reagent. Methods in Enzymology, 299: 152-178.
32. Suckling KE, Jackson B, 1993. Animal models of human lipid metabolism. Progress in Lipid Research, 32: 124.
33. Trease GE, Evans WC, 1983. Pharmacognosy, 12th Edn., Bailliere Tindal, London.
34. Yagi K, 1976. Simple Fluorometric Assay for lipoperoxide in blood plasma. Medical Biochemistry, 15: 212-216.