Apoptosis in human hepatoma HepG2 cells induced by corn peptides and its anti-tumor efficacy in H22 tumor bearing mice

Food and Chemical Toxicology

Volumn 51, Issue 1, 2013, Pages 297-305

  Li, Jiang Tao ^a   Zhang, Jiu Liang ^a   He, Hui ^a   Ma, Zhi Li ^a   Nie, Zhi Kui ^a   Wang, Zhen Zhen ^a   Xu, Xiao Gen ^a  

^a KEY LABORATORY OF ENVIRONMENT CORRELATIVE DIETOLOGY HUAZHONG AGRICULTURAL UNIVERSITY   (China)

Author keywords

Anti tumor; Apoptosis; Corn peptides (CPs); Hepatocellular carcinoma; Immunomodulatory

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CORN PEPTIDE; CYCLOPHOSPHAMIDE; GAMMA INTERFERON; INTERLEUKIN 2; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE S PHASE; CELL STRAIN HEPG2; CELL STRUCTURE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; HUMAN; HUMAN CELL; IMMUNE SYSTEM; IMMUNOMODULATION; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; MALE; MOUSE; NONHUMAN; SOLID TUMOR; SURVIVAL TIME; WESTERN BLOTTING;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CASPASE 3; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HEP G2 CELLS; HUMANS; INTERLEUKIN-2; MALE; MICE; MICE, INBRED BALB C; PLANT PROTEINS; S PHASE CELL CYCLE CHECKPOINTS; SPLEEN; TUMOR NECROSIS FACTOR-ALPHA; ZEA MAYS;

MUS; ZEA MAYS;

EID: 84868252159     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.09.038     Document Type: Article

References (30)

1. Benchimol S. p53-Dependent pathways of apoptosis. Cell Death Differ. 2001, 8:1049-1051.
2. Blanca H.L., Hsieh C.C., Lumen B.O. Lunasin, a novel seed peptide for cancer prevention. Peptides 2009, 30:426-430.
3. Chipuk J.E., Green D.R. p53's Believe it or not: lessons on transcription-independent death. J. Clin. Immunol. 2003, 23:355-361.
4. Chung K.Y., Saltz L.B. Adjuvant therapy of colon cancer: current status and future directions. Cancer J. 2007, 13:192-197.
5. Cohen G.M. Caspases: the executioners of apoptosis. Biochem. J. 1997, 326:1-16.
6. Daniel A.B., Maria C.A. Potential antitumor properties of a protein isolate obtained from the seeds of Amaranthus mantegazzianus. Eur. J. Nutr. 2010, 49:73-82.
7. Ding X., Zhu F.S., Gao S.G. Purification, antitumor and immunomodulatory activity of water-extractable and alkali-extractable polysaccharides from Solanum nigrum L. Food Chem. 2012, 131:677-684.
8. Drake C.G., Antonarakis E.S. Update: immunological strategies for prostate cancer. Curr. Urol. Rep. 2010, 11:202-207.
9. Gansbacher B., Bannerji R., Daniels B., Zier K., Cronin K., Gilboa E. Retroviral vector-mediated gamma-interferon gene transfer into tumor cells generates potent and long lasting antitumor immunity. Cancer Res. 1990, 50:7820-7825.
10. Gapany C., Zhao M., Arthur Z. The apoptosis protector, bcl-2 protein, is downregulated in bile duct epithelial cells of human liver allografts. J. Hepatol. 1997, 26:535-542.
11. Ghobrial M.I., Thomas E.W., Alex A.A. Targeting apoptosis pathways in cancer therapy. CA Cancer J. Clin. 2005, 55:178-194.
12. Gogvadze V., Orrenius S., Zhivotovsky B. Multiple pathways of cytochrome c release from mitochondria in apoptosis. Biochim. Biophys. Acta 2006, 1757:639-647.
13. Guo H., Sun J., He H., Yu G.C., Du J. Antihepatotoxic effect of corn peptides against Bacillus Calmette-Guerin/lipopolysaccharide-induced liver injury in mice. Food Chem. Toxicol. 2009, 10(47):2431-2435.
14. Hsu Y.L., Kuo P.L., Liu C.F., Lin C.C. Acacetin-induced cell cycle arrest and apoptosis in human non-small cell lung cancer A549 cells. Cancer Lett. 2004, 212:53-60.
15. Huang W.H., Sun J., He H., Dong H.W., Li J.T. Antihypertensive effect of corn peptides, produced by a continuous production in enzymatic membrane reactor, in spontaneously hypertensive rats. Food Chem. 2011, 4(128):968-973.
16. Kerr J.F.R., Wyllie A.H., Currie A.R. Apoptosis: a basic biological phenomenon with wide ranging implications in tissue kinetic. Br. J. Cancer 1972, 26:239.
17. Lee J.S., Hong E.K. Hericium erinaceus enhances doxorubicin-induced apoptosis in human. Cancer Lett. 2010, 297:144-154.
18. Lejeune F.J., Liénard D., Matter M., Rüegg C. Efficiency of recombinant human TNF in human cancer therapy. Cancer Immun. 2006, 6:6-16.
19. Li H.M., Hu X., Guo P., Fu P., Xu L., Zhang X.Z. Antioxidant properties and possible mode of action of corn protein peptides and zein peptides. J. Food Biochem. 2010, 34:44-60.
20. Mancini M., Nicholson D.W., Roy S., et al. The caspase-3 precursor has a cytosolic and mitochondrial distribution: implications for apoptotic signaling. J. Cell Biol. 1998, 140:1485-1495.
21. Tu J., Sun H.X., Ye Y.P. Immunomodulatory and antitumor activity of triterpenoid fractions from the rhizomes of Astilbe chinensis. J. Ethnopharmacol. 2008, 119:266-271.
22. Wang G., Zhao J., Liu J.W., Huang Y.P., Zhong J.J., Tang W. Enhancement of IL-2 and IFN-γ expression and NK cells activity involved in the anti-tumor effect of ganoderic acid in vivo. Int. Immunopharmacol. 2007, 7:864-870.
23. Xue Z.H., Liu Z.W., Wu M.C., Zhuang S.W., Yu W.C. Effect of rapeseed peptide on DNA damage and apoptosis in Hela cells. Exp. Toxicol. Pathol. 2010, 62:519-523.
24. Yamaguchi M., Takeuchi M., Ebihara K. Inhibitory effect of peptide prepared from corn gluten meal on 7,12-dimethylbenz [A] anthracene-induced mammary tumor progression in rats. Nutr. Res. 1997, 7(17):1121-1130.
25. Yao H.J., Ju R.J., Wang X.X., Zhang Y., Li R.J., Yu Y., Zhang L., Lu W.L. The antitumor efficacy of functional paclitaxel nanomicelles in treating resistant breast cancers by oral delivery. Biomaterials 2011, 12(32):3285-3302.
26. Yu J., Wang Z., Kinzler K.W., et al. PUMA mediates the apoptotic response to p53 in colorectal cancer cells. Proc. Natl. Acad. Sci. USA 2003, 100:1931-1936.
27. Yu G.C., Li J.T., He H., Huang W.H., Zhang W.J. Ultrafiltration preparation of potent bioactive corn peptide as alcohol metabolism stimulator in vivo, and study on its mechanism of action. J. Food Biochem. 2011, 10.1111/J1745-4514.2011.00613.X.
28. Yu G.C., Lv J., He H., Huang W.H., Han Y. Hepatoprotective effects of corn peptides against carbon tetrachloride-induced liver injury in mice. J. Food Biochem. 2012, 36:458-464.
29. Yuan J., Yankner B.A. Apoptosis in the nervous system. Nature 2000, 407:802-809.
30. Zhang L., Li X.L., Xua X.J., Zeng F.B. Correlation between antitumor activity, molecular weight, and conformation of lentinan. Carbohydr. Res. 2005, 340:1515-1521.