Properties of a novel PBP2A protein homolog from staphylococcus aureus strain LGA251 and its contribution to the β-lactam-resistant phenotype

Journal of Biological Chemistry

Volumn 287, Issue 44, 2012, Pages 36854-36863

  Kim, Choonkeun ^a   Milheiriço, Catarina ^b   Gardete, Susana ^a,b   Holmes, Mark A ^c   Holden, Matt T G ^d   De Lencastre, Hermínia ^a,b   Tomasz, Alexander ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA   (Portugal)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

LOW RESISTANCE; S. AUREUS; STAPHYLOCOCCUS AUREUS;

BACTERIA;

PROTEINS;

BETA LACTAM ANTIBIOTIC; CEFOXITIN; GLYCOSYLTRANSFERASE; OXACILLIN; PENICILLIN BINDING PROTEIN 2A;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; BINDING AFFINITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; EPSILOMETER TEST; ESCHERICHIA COLI; GEL MOBILITY SHIFT ASSAY; IC 50; MECI GENE; MECR GENE; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR CLONING; NONHUMAN; PHENOTYPE; PLASMID; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PURIFICATION; PROTEIN STABILITY; REGULATOR GENE; REGULATORY SEQUENCE; SEQUENCE HOMOLOGY; STAPHYLOCOCCUS AUREUS; STRAIN DIFFERENCE; THERMOSTABILITY;

AMINOACYLTRANSFERASES; BACTERIAL PROTEINS; BETA-LACTAM RESISTANCE; BORON COMPOUNDS; CEFOXITIN; CELL MEMBRANE; CLONING, MOLECULAR; ENZYME STABILITY; INHIBITORY CONCENTRATION 50; MICROBIAL SENSITIVITY TESTS; MOLECULAR WEIGHT; OXACILLIN; PENICILLINS; PHENOTYPE; PROTEIN STRUCTURE, SECONDARY; SEQUENCE HOMOLOGY, AMINO ACID; STAPHYLOCOCCUS AUREUS; SUBSTRATE SPECIFICITY;

METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS AUREUS;

EID: 84868232117     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.395962     Document Type: Article

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