Activation of 5-HT7 serotonin receptors reverses metabotropic glutamate receptor-mediated synaptic plasticity in wild-type and fmr1 knockout mice, a model of fragile X syndrome

Biological Psychiatry

Volumn 72, Issue 11, 2012, Pages 924-933

  Costa, Lara ^a   Spatuzza, Michela ^b   D'Antoni, Simona ^b   Bonaccorso, Carmela M ^c   Trovato, Chiara ^c   Musumeci, Sebastiano A ^c   Leopoldo, Marcello ^d   Lacivita, Enza ^d   Catania, Maria V ^b,c   Ciranna, Lucia ^a  

^a UNIVERSITY OF CATANIA   (Italy)

^b INSTITUTE OF NEUROLOGICAL SCIENCES   (Italy)

^c OASI RESEARCH INSTITUTE IRCCS   (Italy)

^d UNIVERSITY OF BARI   (Italy)

Author keywords

5 HT7; AMPA receptor; Fmr1 KO; Fragile X; hippocampus; mGluR LTD

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 3 [2 [2 (4 METHYL 1 PIPERIDINYL)ETHYL] 1 PYRROLIDINESULFONYL]PHENOL; LP 211; METABOTROPIC RECEPTOR 2; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; SEROTONIN; SEROTONIN 7 RECEPTOR; SEROTONIN AGONIST; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; FRAGILE X SYNDROME; HIPPOCAMPUS; LONG TERM DEPRESSION; MALE; MOUSE; NERVE CELL; NONHUMAN; PRESYNAPTIC NERVE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANIMALS; DISEASE MODELS, ANIMAL; EXCITATORY POSTSYNAPTIC POTENTIALS; FRAGILE X MENTAL RETARDATION PROTEIN; FRAGILE X SYNDROME; HIPPOCAMPUS; LONG-TERM SYNAPTIC DEPRESSION; MICE; MICE, KNOCKOUT; MINIATURE POSTSYNAPTIC POTENTIALS; RECEPTORS, SEROTONIN; SEROTONIN; SEROTONIN RECEPTOR AGONISTS;

EID: 84868198902     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2012.06.008     Document Type: Article

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