Free fatty acids inhibit TM-EPCR expression through JNK pathway: An implication for the development of the prothrombotic state in metabolic syndrome

Journal of Thrombosis and Thrombolysis

Volumn 34, Issue 4, 2012, Pages 468-474

  Xie, Wanmu ^a,b   Zhai, Zhenguo ^a,b   Yang, Yuanhua ^a,b   Kuang, Tuguang ^a,b   Wang, Chen ^b,c  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b Beijing Institute of Respiratory Medicine   (China)

^c BEIJING HOSPITAL   (China)

Author keywords

Endothelial protein C receptor; Free fatty acids; JNK; Thrombomodulin; Thrombosis

Indexed keywords

ENDOTHELIAL PROTEIN C RECEPTOR; ENDOTHELIAL THROMBOMODULIN; FATTY ACID; PALMITIC ACID; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; THROMBOMODULIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLEEDING TIME; CONTROLLED STUDY; DEEP VEIN THROMBOSIS; ENDOTHELIUM CELL; FATTY ACID BLOOD LEVEL; HUMAN; HUMAN CELL; LIPID DIET; MALE; METABOLIC SYNDROME X; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTHROMBOTIC STATE; SIGNAL TRANSDUCTION; TAIL; THROMBOSIS; UMBILICAL VEIN ENDOTHELIAL CELL; WESTERN BLOTTING;

ANIMALS; ANTIGENS, CD; BLEEDING TIME; CELLS, CULTURED; DIETARY FATS; FATTY ACIDS, NONESTERIFIED; GENE EXPRESSION REGULATION; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MALE; MAP KINASE KINASE 4; METABOLIC SYNDROME X; MICE; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; THROMBOMODULIN; VENOUS THROMBOSIS;

EID: 84868194513     PISSN: 09295305     EISSN: 1573742X     Source Type: Journal    
DOI: 10.1007/s11239-012-0793-8     Document Type: Article

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